Abstract：
:It has been proposed that certain psychotic symptoms associated with schizophrenia reflect a deficit in the ability to appreciate other people's mental states (Frith, 1992). This notion is tested using a newly devised task examining the capacity to infer intentions behind indirect speech. The findings support the notion that some patients with schizophrenia have difficulties with tasks requiring 'theory of mind' skills and that this deficiency is symptom specific. The findings are discussed with reference to the cognitive skills which may be involved in the performance of tasks requiring social inferences.
journal_name
Schizophr Resjournal_title
Schizophrenia researchauthors
Corcoran R,Mercer G,Frith CDdoi
10.1016/0920-9964(95)00024-gsubject
Has Abstractpub_date
1995-09-01 00:00:00pages
5-13issue
1eissn
0920-9964issn
1573-2509pii
092099649500024Gjournal_volume
17pub_type
杂志文章abstract：OBJECTIVE:The aim of this study was to test the goodness-of-fit of all previously published five-factor models of the Positive and Negative Syndrome Scale (PANSS). METHODS:We used confirmatory factor analysis (CFA) with a large data set (N = 5769). RESULTS:The different subsamples were tested for heterogeneity and we...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2006.04.001
更新日期：2006-07-01 00:00:00
abstract：:The presence of delusions is considered a key feature of psychosis, but despite the psychopathological centrality of the concept of delusion, its definition and comprehension is a matter of continuing debate. In recent years studies showing that delusions are common in the general population have accumulated and chall...
journal_title：Schizophrenia research
pub_type： 杂志文章,评审
doi：10.1016/j.schres.2019.10.043
更新日期：2020-02-01 00:00:00
abstract：:Recent trials support the hypothesis of the role of inflammation in the pathogenesis of schizophrenia. The overall therapeutic benefit of anti-inflammatory medication, in particular cyclo-oxygenase-2 (COX-2) inhibitors in schizophrenia, is still controversial. There are suggestions that therapy with COX-2 inhibitors m...
journal_title：Schizophrenia research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.schres.2010.04.015
更新日期：2010-08-01 00:00:00
abstract：:Characterizing a pattern of cognitive dysfunction in early onset schizophrenic patients may illuminate neurodevelopmental contributions to the illness. A cohort of chronically institutionalized schizophrenic patients with a variable range of age of onset (range 7-29 years) was administered a comprehensive battery of n...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/0920-9964(95)00065-8
更新日期：1996-05-01 00:00:00
abstract：:Increased rates of comorbid physical illness have been commonly reported in patients with schizophrenia. However, there are fewer data on dental disease in these patients. We systematically evaluated existing data on the oral health survey of schizophrenia patients through meta-analysis. Using the available databases,...
journal_title：Schizophrenia research
pub_type： 杂志文章,meta分析
doi：10.1016/j.schres.2018.04.031
更新日期：2018-11-01 00:00:00
abstract：:The current study examined whether patterns of emotional response are differentially associated with symptom presentation and functional outcome in individuals with schizophrenia. Participants included 49 outpatients with schizophrenia and 50 demographically matched controls. All participants rated their emotional res...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2011.01.010
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:The Recovery Assessment Scale (RAS) is one of the most widely used measurements of recovery in mental health research. To date, no data have been available concerning the psychometric characteristics of the RAS in homeless people with severe mental illness. The aim of this study was to provide new data regard...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2015.10.007
更新日期：2015-12-01 00:00:00
abstract：:Schizophrenia is a heterogeneous spectrum disorder often associated with detrimental negative symptoms. In recent years, computational approaches to psychiatry have attracted growing attention. Negative symptoms have shown some overlap with general cognitive impairments and were also linked to impaired motivational pr...
journal_title：Schizophrenia research
pub_type： 杂志文章,评审
doi：10.1016/j.schres.2016.10.004
更新日期：2017-08-01 00:00:00
abstract：:Schizophrenia is modelled as a neurodevelopmental disease with high heritability. However, established markers like cortical thickness and grey matter volume are heavily influenced by post-onset changes and thus provide limited possibility of accessing early pathologies. Gyrification on the other side is assumed to be...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2018.07.014
更新日期：2018-12-01 00:00:00
abstract：:Many children of a schizophrenic parent may inherit a portion of the genetic risk factors for schizophrenia. The frequency of DSM-IV psychopathology in children of a schizophrenic parent and the frequency and type of mental health treatment accessed by these youths is not well understood. Twenty-eight adults with schi...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(00)00043-8
更新日期：2001-05-30 00:00:00
abstract：:Estrogen has been shown in animal studies to modulate both the dopamine and serotonin neurotransmitter systems - the main neurotransmitters implicated in the pathogenesis of schizophrenia. A double blind, 28 day, placebo-controlled study was conducted with three groups of women of child-bearing age (N=12 in each group...
journal_title：Schizophrenia research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0920-9964(00)00088-8
更新日期：2001-03-01 00:00:00
abstract：:Schizophrenia is associated with structural brain abnormalities that are likely to be present before disease onset. It remains unclear to what extent these represent general vulnerability indicators or are associated with the developing clinical state itself. It also remains unclear whether such state or trait alterat...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2014.12.003
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:Functional remission (FR) is an intermediate and necessary step toward recovery, but is understudied in first-episode psychosis (FEP). We aimed to examine the rate and predictors of FR in FEP patients in the context of a randomized-controlled trial (RCT) comparing a 1-year extension of early intervention (Ex...
journal_title：Schizophrenia research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.schres.2016.03.016
更新日期：2016-05-01 00:00:00
abstract：:Studies defining the course and outcome of individuals experiencing their first episode (FE) of psychosis generally report an improvement in symptoms and functioning. Today, many FE patients are treated in specialized early psychosis programs. Little is known what happens to these individuals after discharge from thes...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2008.08.032
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:Reduced procreation among men with schizophrenia has been reported consistently when compared with female patients, but the cause is unknown. Reports on Caucasian individuals predominate in the published literature. Therefore, analyses were conducted concurrently among independent Indian and US samples in the...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2003.08.009
更新日期：2004-06-01 00:00:00
abstract：:Previous transcriptome analyses of brain samples provided several insights into the pathophysiology of schizophrenia. In this study, we aimed to re-investigate gene expression datasets from seven brain regions of patients with schizophrenia and healthy controls by adopting a unified approach. After adjustment for conf...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2020.06.032
更新日期：2020-09-01 00:00:00
abstract：:Past studies have shown that schizophrenic men tend to be impaired on the olfactory identification task. We examined individual differences in the olfactory function in relation to schizotypy. Healthy individuals who might carry latent liability for schizophrenia participated in olfactory identification and acuity tas...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(97)00045-5
更新日期：1997-08-29 00:00:00
abstract：:Increased sulcal widening in the prefrontal cortex of patients with schizophrenia may be associated with a poor treatment response to clozapine. To further evaluate this, we examined data from patients treated with clozapine in our center. Patients with the greatest degree of improvement (n=26) and those with no impro...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(00)00130-4
更新日期：2001-03-30 00:00:00
abstract：:Defeatist beliefs and amotivation are prominent obstacles in vocational rehabilitation for people with serious mental illnesses (SMI). The CBT-based Indianapolis Vocational Intervention Program (IVIP) was specifically designed to reduce defeatist beliefs related to work functioning. In the current study, we examined t...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2016.10.036
更新日期：2017-04-01 00:00:00
abstract：INTRODUCTION:Childhood abuse and neglect are risk factors for psychotic symptoms. Early adversities may contribute to alterations in neuro/social cognition, which in turn is associated with psychosis. This study explored the possible mediating/moderating role of neuro/social cognition between childhood abuse and neglec...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2018.11.028
更新日期：2019-04-01 00:00:00
abstract：:Stigma may undermine the well-being of young people at risk of psychosis. We therefore measured self-labeling, stigma variables and well-being at baseline and again one year later among 77 at-risk participants. An increase in self-labeling during this period predicted heightened stigma stress after one year and a decr...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2014.07.016
更新日期：2014-09-01 00:00:00
abstract：:The EPSILON project (European Psychistric Services: Inputs Linked to Outcomes and Needs) is a cross-sectional study of the clinical and social characteristics, needs, satisfaction with services, quality of life, and service utilisation and costs for people with schizophrenia in five European sites (Amsterdam, Copenhag...
journal_title：Schizophrenia research
pub_type： 杂志文章,多中心研究
doi：10.1016/s0920-9964(01)00318-8
更新日期：2002-10-01 00:00:00
abstract：:Since the recognition that adults with velocardiofacial syndrome (VCFS), which is associated with hemizygous interstitial deletions of chromosome 22q11, frequently show psychotic symptoms, deletion of the 22q11.2 region has been proposed as a common genetic abnormality associated with schizophrenia. In studies of schi...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(00)00192-4
更新日期：2001-12-01 00:00:00
abstract：BACKGROUND:Appropriate expression of emotions and correct perception of emotional expression in others are important social skills which may be impaired in schizophrenia and contribute to poor social adjustment. We examined the relationship between expression of emotions as measured by affective flattening and other ne...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(00)00093-1
更新日期：2001-12-01 00:00:00
abstract：:Research into the neurobiological processes that may lead to the onset of schizophrenia places growing emphasis on the glutamatergic system and brain development. Preclinical studies have shown that neurodevelopmental, genetic, and environmental factors contribute to glutamatergic dysfunction and schizophrenia-related...
journal_title：Schizophrenia research
pub_type： 杂志文章,评审
doi：10.1016/j.schres.2020.09.013
更新日期：2020-09-01 00:00:00
abstract：:Social perception and mentalizing are fundamental social cognitive abilities that are related to functioning and are impaired in schizophrenia. A novel approach to examine the relationship between social cognition and community functioning is to first functionally categorize individuals with schizophrenia and then eva...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2016.01.029
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Cannabis and cocaine are the most common illicit drugs for which people are treated in addiction services in Latin America. Much research has suggested that the use of cannabis increases the risk of schizophrenia; there is less evidence concerning cocaine. The aim of the present study was to establish the re...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2017.04.010
更新日期：2018-04-01 00:00:00
abstract：:The author previously proposed that schizophrenia has similar cytokine expression compared to melanoma, a neural crest cell tumor. One possible tumor model of schizophrenia includes anti-NMDA receptor encephalitis, a paraneoplastic syndrome. While examining the possible relationship of neural crest cell tumors to schi...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2016.08.012
更新日期：2016-10-01 00:00:00
abstract：INTRODUCTION:This study investigates the effect of exposure to "The Troubles" (the period of civil unrest from 1968 onwards) in Northern Ireland on symptomatology in people with schizophrenia. METHOD:Eighty-two participants were assessed on a number of psychiatric rating scales and on measures of trauma, including an ...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2008.02.012
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:Formal thought disorder (FTD) is a core feature of psychosis, however there are gaps in our knowledge about its prevalence and factor structure. We had two aims: first, to establish the factor structure of FTD; second, to explore the clinical utility of dimensions of FTD in order to further the understanding...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2015.07.049
更新日期：2015-10-01 00:00:00
