Abstract：
:Many children of a schizophrenic parent may inherit a portion of the genetic risk factors for schizophrenia. The frequency of DSM-IV psychopathology in children of a schizophrenic parent and the frequency and type of mental health treatment accessed by these youths is not well understood. Twenty-eight adults with schizophrenia were identified and 43 of their 6--15 year old children recruited. Clinical diagnoses, based on a structured DSM-IV interview; severity of impairment, based on the Child Global Assessment Scale; and treatment histories were obtained. Seventy-four per cent of children-with-a-schizophrenic-parent met diagnostic criteria for a current Axis I psychiatric disorder. The most common diagnostic categories included attention deficit/hyperactivity disorder (40%), any anxiety disorder (23%), and any depressive disorder (12%). Psychosis was present in 9% of this childhood sample. Of those children with a psychiatric diagnosis, 47% demonstrated current moderate or severe impairment. Approximately half of the children had received mental health evaluations and 26% had experienced at least one psychiatric medication trial. Children-with-a-schizophrenic-parent have frequent, often impairing, psychiatric problems. Despite this high prevalence, mental health evaluation and treatment is of similar frequency and type to other at-risk populations. The effectiveness and appropriateness of standard treatments remain unstudied in children-with-a-schizophrenic-parent.
journal_name
Schizophr Resjournal_title
Schizophrenia researchauthors
Ross RG,Compagnon Ndoi
10.1016/s0920-9964(00)00043-8subject
Has Abstractpub_date
2001-05-30 00:00:00pages
121-9issue
1-2eissn
0920-9964issn
1573-2509pii
S0920-9964(00)00043-8journal_volume
50pub_type
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pub_type： 杂志文章,多中心研究
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pub_type： 杂志文章
doi：10.1016/j.schres.2007.08.024
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pub_type： 杂志文章,评审
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更新日期：2005-04-01 00:00:00
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journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2016.02.006
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pub_type： 杂志文章,meta分析,评审
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：1992-04-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/j.schres.2006.07.006
更新日期：2006-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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更新日期：2007-08-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章,随机对照试验
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更新日期：2019-01-01 00:00:00
