Abstract：
:Enhancing work function is now widely considered a core element of comprehensive schizophrenia treatment. While research efforts have illuminated factors that influence how well patients perform at work, less is known about the factors influencing the subjective experience of work. It is not known how, and to what extent, symptoms, cognitive deficits or metacognitive capacities impact job satisfaction and whether treatment can have an effect on job satisfaction. To explore this issue, data from a trial in which participants in a six-month vocational program were assigned to either a standard support group or a cognitive behavioral group therapy, and asked to fill in weekly self-reports of job satisfaction was analyzed. Work satisfaction and the consistency of these ratings were compared between the two groups and the moderating influence of metacognitive capacity was analyzed. A significant interaction effect revealed that higher metacognitive capacity predicted higher average job satisfaction only in the CBT group. Additionally, higher metacognitive capacity led to a more varied appraisal of work satisfaction only in the support group.
journal_name
Schizophr Resjournal_title
Schizophrenia researchauthors
de Jong S,Renard SB,van Donkersgoed RJ,van der Gaag M,Wunderink L,Pijnenborg GH,Lysaker PHdoi
10.1016/j.schres.2014.04.017subject
Has Abstractpub_date
2014-08-01 00:00:00pages
107-11issue
1-3eissn
0920-9964issn
1573-2509pii
S0920-9964(14)00189-3journal_volume
157pub_type
杂志文章abstract：BACKGROUND:Aberrations in body perception are common in psychotic disorders. The insula and temporoparietal junction (TPJ) are involved in body ownership and spatial perception suggesting that abnormal structure of these regions might be related to the expression of perceptual aberrations in psychosis. METHODS:58 indi...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2016.10.005
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:The 22q11.2 deletion syndrome (22q11DS) is one of the highest known risk factors for schizophrenia and recent findings have highlighted the clinical relevance of ultra-high risk (UHR) criteria in this population. However, studies in other at-risk populations have shown that the presence of negative symptoms ...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2018.10.014
更新日期：2019-04-01 00:00:00
abstract：:While the long-term administration of antipsychotics is known to cause dopamine supersensitivity psychosis (DSP), recent studies revealed that DSP helps form the foundation of treatment resistance. Electroconvulsive shock (ES) is one of the more effective treatments for treatment-resistant schizophrenia. The objective...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2020.11.062
更新日期：2021-01-08 00:00:00
abstract：OBJECTIVES:Recent reports of antibodies to heat shock proteins 60kDa (HSP60) and HSP70 suggested that antibodies to the heat shock protein that plays a protective role against environmental stresses in a cell might be related to the pathogenesis of schizophrenia, although the antibody to HSP90 had not yet been identifi...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(00)00091-8
更新日期：2001-10-01 00:00:00
abstract：:Glutamate was quantified by proton magnetic resonance spectroscopy ((1)H-MRS) in the medial frontal lobes of 15 adult siblings of individuals with schizophrenia (HR) and 14 healthy volunteers (HV), all of whom also completed a Continuous Performance Test (CPT). Subjects were free of psychopathology but the HR group sh...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2007.11.028
更新日期：2008-02-01 00:00:00
abstract：:Valid criteria to identify young people who are believed to be at ultra high risk (UHR) of developing a psychotic episode were developed over the last decade. The first randomized controlled trial of treatment in a UHR cohort indicated that specific pharmacotherapy and psychotherapy delayed onset of disorder, and poss...
journal_title：Schizophrenia research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.schres.2007.05.018
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVE:Supported employment is the evidence-based treatment of choice for assisting individuals with severe mental illness to achieve competitive employment, but few supported employment programs specifically target older clients with psychiatric illness. The purpose of this study was to evaluate the efficacy of sup...
journal_title：Schizophrenia research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.schres.2011.11.036
更新日期：2012-03-01 00:00:00
abstract：:Few studies have been conducted examining cytokines in cerebrospinal fluid of patients compared to healthy volunteers. The goals of this study were: 1) to report original data detailing cytokine levels in the cerebrospinal fluid (CSF) of 10 patients with a schizophrenia spectrum disorder (SSD) diagnosis and 10 healthy...
journal_title：Schizophrenia research
pub_type： 杂志文章,meta分析
doi：10.1016/j.schres.2018.07.019
更新日期：2018-12-01 00:00:00
abstract：:Stigma may undermine the well-being of young people at risk of psychosis. We therefore measured self-labeling, stigma variables and well-being at baseline and again one year later among 77 at-risk participants. An increase in self-labeling during this period predicted heightened stigma stress after one year and a decr...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2014.07.016
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:While the functional disconnectivity hypothesis of schizophrenia has received considerable attention, fewer studies have investigated the contribution of genotype to structural connectivity between brain regions either in schizophrenia patients or in healthy controls. In this study, we obtained diffusion ten...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2014.03.003
更新日期：2014-05-01 00:00:00
abstract：:Recovery-oriented practices that promote client-centered care, collaboration, and functional outcome have been recommended to improve treatment engagement, especially for individuals with serious mental illness (SMI). Psychological well-being (PWB) is related to recovery and refers to experiencing purpose and meaning ...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2016.11.032
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVE:Amoxapine is marketed as an antidepressant. However, its receptor occupancy, in vitro and in vivo, and its effects in pre-clinical models are very similar to atypical antipsychotics. To examine if this leads to an atypical antipsychotic effect in the clinical context, the authors examined the antipsychotic an...
journal_title：Schizophrenia research
pub_type： 临床试验,杂志文章
doi：10.1016/s0920-9964(01)00342-5
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND:Randomized trials targeting cannabis use disorders in patients with psychosis have generally been unsuccessful. One of the largest such trials was the CapOpus trial, which had an impact on the number of monthly joints used, but not on the number of days with cannabis use or positive or negative symptoms. OB...
journal_title：Schizophrenia research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.schres.2013.10.014
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Appropriate expression of emotions and correct perception of emotional expression in others are important social skills which may be impaired in schizophrenia and contribute to poor social adjustment. We examined the relationship between expression of emotions as measured by affective flattening and other ne...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/s0920-9964(00)00093-1
更新日期：2001-12-01 00:00:00
abstract：:Numerous studies have described attenuated event-related potential (ERP) component amplitudes in schizophrenia (e.g., P300, Mismatch Negativity (MMN), Error Negativity/Error-Related Negativity (Ne/ERN)). Functional magnetic resonance imaging (fMRI) studies have typically shown decreased recruitment of diverse brain ar...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2009.09.036
更新日期：2009-12-01 00:00:00
abstract：:Recent studies suggest that both executive dysfunction and personality traits combine with symptoms to affect the social outcome of persons with schizophrenia. This study was designed to investigate how personality traits influence executive function in schizophrenia. Forty-four patients with schizophrenia and twenty-...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2008.06.002
更新日期：2008-09-01 00:00:00
abstract：:EEGs were recorded from 32 channels in 30 normal males, ages 16-22. Delta activity decreased throughout this age range. This decrease was greatest in the left frontal and temporal regions; no occipital lead showed this pattern. Relative EEG amplitude analysis, based on normalized maps, revealed decreases with age acro...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/0920-9964(92)90039-8
更新日期：1992-07-01 00:00:00
abstract：:Schizophrenia is an illness characterized by positive symptoms, negative symptoms, and cognitive impairments. Cognitive impairments occur before the onset of psychosis and could reflect glutamatergic dysregulation. Thus, identifying associations between genetic variations in genes coding for glutamatergic receptors an...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2020.06.019
更新日期：2020-07-02 00:00:00
abstract：:Cholesterol metabolism is vital for brain function. Previous work in cultured cells has shown that a number of psychotropic drugs inhibit the activity of 7-dehydrocholesterol reductase (DHCR7), an enzyme that catalyzes the final steps in cholesterol biosynthesis. This leads to the accumulation of 7-dehydrocholesterol ...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2017.02.001
更新日期：2017-09-01 00:00:00
abstract：:Characterizing a pattern of cognitive dysfunction in early onset schizophrenic patients may illuminate neurodevelopmental contributions to the illness. A cohort of chronically institutionalized schizophrenic patients with a variable range of age of onset (range 7-29 years) was administered a comprehensive battery of n...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/0920-9964(95)00065-8
更新日期：1996-05-01 00:00:00
abstract：:A key predictor of whether or not an individual who hears voices (auditory verbal hallucinations; AVH) meets criteria for a psychiatric diagnosis is the level of negative content of the voices (e.g., threats, criticism, abuse). Yet the factors that contribute to negative voice-content are still not well understood. Th...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2018.03.030
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Anomalies in visual and auditory perception represent an important aspect of the symptomatic manifestation of schizophrenia (ScZ). However, there are currently no instruments available that allow the assessment of the full range of auditory and visual abnormalities using a self-report measure. METHODS:We de...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2019.03.016
更新日期：2019-07-01 00:00:00
abstract：:Previous studies have indicated that schizophrenic patients have olfactory deficits. The question as to whether olfactory deficits are due to chronic effects of medication has not been addressed. This is the first paper to report that never-medicated schizophrenic patients also have olfactory deficits. Twenty four nor...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/0920-9964(93)90008-7
更新日期：1993-03-01 00:00:00
abstract：:Studying Klinefelter syndrome (47,XXY), a genetically defined disorder characterized by the presence of an additional X chromosome, can reveal insights into genotype-phenotype associations. Increased vulnerability to psychiatric disorders characterized by difficulties in social interactions, such as schizophrenia and ...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2006.02.020
更新日期：2006-06-01 00:00:00
abstract：:Here, we used data from large genome-wide association studies to test the presence of causal relationships, conducting a Mendelian randomization analysis; and shared molecular mechanisms, calculating the genetic correlation, among schizophrenia, type 2 diabetes (T2D), and impaired glucose homeostasis. Although our Men...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2017.10.033
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:The aim of this study is to determine the rate of persistent negative symptoms according to different criteria during two years of follow-up after first-episode schizophrenia. METHODS:The study sample consisted of 105 patients with first-episode schizophrenia who completed at least 12 months of follow-up pe...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2014.07.021
更新日期：2014-09-01 00:00:00
abstract：:Deficits in emotion perception are common in people with schizophrenia and current research has focused on improving these deficits. In our previous research, we demonstrated that directing attention to salient facial features via attention shaping can improve these deficits among inpatients. In this study, we examine...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2010.05.011
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:The main goal of the present study was to analyze levels of cytokines of the interleukin family (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8 and IL-10), interferon-gamma (IFN-γ), monocyte chemoattractant protein-1 (MCP1), tumor necrosis factor-alpha (TNF-α), and vascular endothelial and endothelial growth factors (V...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2015.08.027
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:Following encouraging results in the early detection of psychotic disorders, interest in the early detection of affective, especially bipolar disorders, has recently been renewed. However, the differentiation between affective disorders with and without psychotic features is often missing, although it has bee...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2012.04.001
更新日期：2012-07-01 00:00:00
abstract：:The purpose of the present study was to investigate the patterns of interregional correlations of serotonin transporter (SERT) availability with glucose metabolism using 7-Tesla magnetic resonance imaging (MRI) and high-resolution positron emission tomography (PET) with 11C-3-amino-4-(2-dimethylaminomethylphenylthio)b...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2016.10.020
更新日期：2017-04-01 00:00:00
