High-level eucaryotic in vivo expression of biologically active measles virus hemagglutinin by using an adenovirus type 5 helper-free vector system.

abstract：:We have previously demonstrated that open reading frame (ORF) 50 and ORF 57 encode transcriptional regulating genes in herpesvirus saimiri. ORF 50, a homolog of Epstein-Barr virus R protein, is a sequence-specific transactivator, whereas ORF 57 acts posttranscriptionally. In this report, we demonstrate that the ORF 57...

journal_title：Journal of virology

authors： Whitehouse A,Cooper M,Hall KT,Meredith DM

更新日期：1998-03-01 00:00:00

abstract：:The development of vaccines against bluetongue, a prevalent livestock disease, has been focused on surface antigens that induce strong neutralizing antibody responses. Because of their antigenic variability, these vaccines are usually serotype restricted. We now show that a single highly conserved nonstructural protei...

journal_title：Journal of virology

authors： Marín-López A,Calvo-Pinilla E,Barriales D,Lorenzo G,Brun A,Anguita J,Ortego J

更新日期：2018-07-31 00:00:00

abstract：:The DA strain of Theiler's murine encephalomyelitis virus persists in the white matter of the spinal cords of susceptible mice. Previous results showed that the difference in susceptibility to viral persistence between the susceptible SJL/J strain and the resistant B10.S strain was due to multiple non-H-2 loci. The re...

journal_title：Journal of virology

authors： Aubagnac S,Brahic M,Bureau JF

更新日期：2002-06-01 00:00:00

abstract：:It was recently shown that the 7a protein of severe acute respiratory syndrome coronavirus induces biochemical changes associated with apoptosis. In this study, the mechanism by which the 7a protein induces apoptosis was examined. The 7a protein was tested for the ability to inhibit cellular gene expression because se...

journal_title：Journal of virology

authors： Kopecky-Bromberg SA,Martinez-Sobrido L,Palese P

更新日期：2006-01-01 00:00:00

abstract：:We have found that interleukin-4 (IL-4) abrogated constitutive beta interferon (IFN-beta) synthesis in mouse macrophages. Analysis of endogenous IFN mRNA by reverse transcription-PCR clearly documented the presence of IFN-beta but not of IFN-alpha transcripts in RNA from bone marrow-derived macrophages (BMM). Culture ...

journal_title：Journal of virology

authors： Nickolaus P,Zawatzky R

更新日期：1994-10-01 00:00:00

abstract：:In vivo decay rates for the individual T7 early mRNA species were determined. The physical half-lives, measured at 37 C, range from 1.1 min for gene 0.7 RNA to 4.5 min for gene 0.3 RNA. Physical half-lives, as observed after rifampin inhibition of RNA synthesis and polyacylamide electrophoresis of RNAs, are approximat...

journal_title：Journal of virology

authors： Hercules K,Jovanovich S,Sauerbrier W

更新日期：1976-02-01 00:00:00

abstract：:The herpes simplex virus (HSV) capsid is released into the cytoplasm after fusion of viral and host membranes, whereupon dynein-dependent trafficking along microtubules targets it to the nuclear envelope. Binding of the capsid to the nuclear pore complex (NPC) is mediated by the capsid protein pUL25 and the capsid-tet...

journal_title：Journal of virology

authors： Huffman JB,Daniel GR,Falck-Pedersen E,Huet A,Smith GA,Conway JF,Homa FL

更新日期：2017-07-12 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) requires that its genome be reverse transcribed into double-stranded DNA for productive infection of cells. This process requires not only reverse transcriptase but also the nucleocapsid protein (NC), which functions as a nucleic acid chaperone. Reverse transcription general...

journal_title：Journal of virology

authors： Thomas JA,Bosche WJ,Shatzer TL,Johnson DG,Gorelick RJ

更新日期：2008-10-01 00:00:00

abstract：:We evaluated the ability of human coronaviruses to infect primary cultures of human neural cells. Double immunofluorescence with antibodies to virus and cell markers showed infection of fetal astrocytes and of adult microglia and astrocytes by strain OC43. RNA amplification revealed infection of fetal astrocytes, adul...

journal_title：Journal of virology

authors： Bonavia A,Arbour N,Yong VW,Talbot PJ

更新日期：1997-01-01 00:00:00

abstract：:The genome of a canine parvovirus isolate strain (CPV-N) was cloned, and the DNA sequence was determined. The entire genome, including ends, was 5,323 nucleotides in length. The terminal repeat at the 3' end of the genome shared similar structural characteristics but limited homology with the rodent parvoviruses. The ...

journal_title：Journal of virology

authors： Reed AP,Jones EV,Miller TJ

更新日期：1988-01-01 00:00:00

abstract：:The first morphological evidence of African swine fever virus (ASFV) assembly is the appearance of precursor viral membranes, thought to derive from the endoplasmic reticulum, within the assembly sites. We have shown previously that protein p54, a viral structural integral membrane protein, is essential for the genera...

journal_title：Journal of virology

authors： Suárez C,Gutiérrez-Berzal J,Andrés G,Salas ML,Rodríguez JM

更新日期：2010-08-01 00:00:00

abstract：:Purified avian myeloblastosis virus was iodinated by the lactoperoxidase method. Disruption of the labeled virions and chromatography of the viral proteins showed that radioiodine was associated only with the glycoproteins of the viral envelope. Reaction of the radiolabeled virus with antiviral antibody followed by mi...

journal_title：Journal of virology

authors： Fritz RB

更新日期：1974-01-01 00:00:00

abstract：:In an attempt to generate broadly cross-reactive, neutralizing monoclonal antibodies (MAbs) to simian immunodeficiency virus (SIV), we compared two immunization protocols using different preparations of oligomeric SIV envelope (Env) glycoproteins. In the first protocol, mice were immunized with soluble gp140 (sgp140) ...

journal_title：Journal of virology

authors： Edinger AL,Ahuja M,Sung T,Baxter KC,Haggarty B,Doms RW,Hoxie JA

更新日期：2000-09-01 00:00:00

abstract：:The family Caliciviridae is divided into four genera and consists of single-stranded RNA viruses with hosts ranging from humans to a wide variety of animals. Human caliciviruses are the major cause of outbreaks of acute nonbacterial gastroenteritis, whereas animal caliciviruses cause various host-dependent illnesses w...

journal_title：Journal of virology

authors： Chen R,Neill JD,Noel JS,Hutson AM,Glass RI,Estes MK,Prasad BV

更新日期：2004-06-01 00:00:00

abstract：UNLABELLED:A hallmark of Ebola virus (EBOV) infection is the formation of viral inclusions in the cytoplasm of infected cells. These viral inclusions contain the EBOV nucleocapsids and are sites of viral replication and nucleocapsid maturation. Although there is growing evidence that viral inclusions create a protected...

journal_title：Journal of virology

authors： Nelson EV,Schmidt KM,Deflubé LR,Doğanay S,Banadyga L,Olejnik J,Hume AJ,Ryabchikova E,Ebihara H,Kedersha N,Ha T,Mühlberger E

更新日期：2016-07-27 00:00:00

abstract：:Leishmania RNA virus (LRV) is a double-stranded RNA virus that infects some strains of the protozoan parasite leishmania As with other totiviruses, LRV presumably expresses its polymerase by a ribosomal frameshift, resulting in a capsid-polymerase fusion protein. We have demonstrated previously that an LRV capsid-poly...

journal_title：Journal of virology

authors： Carrion R Jr,Ro YT,Patterson JL

更新日期：2003-10-01 00:00:00

abstract：:Papilloma virus DNA from a laryngeal papilloma was cloned in phage lambda L 47 and characterized after cleavage with different restriction enzymes. Hybridization with the DNAs of human papilloma virus types 1, 2, 3, 4, 5, and 8 showed no homology under stringent hybridization conditions. Human papilloma virus type 6 D...

journal_title：Journal of virology

authors： Gissmann L,Diehl V,Schultz-Coulon HJ,zur Hausen H

更新日期：1982-10-01 00:00:00

abstract：:During lytic infection, herpes simplex virus subverts the host cell RNA polymerase II transcription machinery to efficiently express its own genome while repressing the expression of most cellular genes. The mechanism by which RNA polymerase II is directed to the viral delayed-early and late genes is still unresolved....

journal_title：Journal of virology

authors： Rice SA,Long MC,Lam V,Spencer CA

更新日期：1994-02-01 00:00:00

abstract：:The late 19S RNAs of simian virus 40 (SV40) are functionally polycistronic, i.e., all encode both VP2 and VP3. The VP3-coding sequences are situated in the same reading frame as the VP2-coding sequences, within the carboxy-terminal two-thirds of the VP2-coding sequences. To test whether VP3 is produced by proteolytic ...

journal_title：Journal of virology

authors： Sedman SA,Mertz JE

更新日期：1988-03-01 00:00:00

abstract：UNLABELLED:The disease mechanisms associated with onset and secondary effects of rotavirus (RV) diarrhea remain to be determined and may not be identical. In this study, we investigated whether onset of RV diarrhea is associated with increased intestinal permeability and/or motility. To study the transit time, fluoresc...

journal_title：Journal of virology

authors： Istrate C,Hagbom M,Vikström E,Magnusson KE,Svensson L

更新日期：2014-03-01 00:00:00

abstract：:The phenotypic properties of ICP27 temperature-sensitive and deletion mutants and the results of transient expression assays have demonstrated that ICP27 has a modulatory effect on viral gene expression induced by ICPs 0 and 4. In order to identify the regions of the ICP27 molecule that are responsible for its enhanci...

journal_title：Journal of virology

authors： McMahan L,Schaffer PA

更新日期：1990-07-01 00:00:00

abstract：:The phenomenon of prion strains with distinct biological characteristics has been hypothesized to be involved in the structural diversity of abnormal prion protein (PrP(Sc)). However, the molecular basis of the transmission of strain properties remains poorly understood. Real-time quaking-induced conversion (RT-QUIC) ...

journal_title：Journal of virology

authors： Sano K,Atarashi R,Ishibashi D,Nakagaki T,Satoh K,Nishida N

更新日期：2014-10-01 00:00:00

abstract：:Since most human immunodeficiency virus (HIV) infections are initiated following mucosal exposure to the virus, the anatomic containment or abortion of an HIV infection is likely to require vaccine-elicited cellular immune responses in those mucosal sites. Studying vaccine-elicited mucosal immune responses has been pr...

journal_title：Journal of virology

authors： Baig J,Levy DB,McKay PF,Schmitz JE,Santra S,Subbramanian RA,Kuroda MJ,Lifton MA,Gorgone DA,Wyatt LS,Moss B,Huang Y,Chakrabarti BK,Xu L,Kong WP,Yang ZY,Mascola JR,Nabel GJ,Carville A,Lackner AA,Veazey RS,Letvin N

更新日期：2002-11-01 00:00:00

abstract：:The minor glycoproteins from hepatitis B surface antigen, GP33 and GP36, contain at their carboxy-terminal part the sequence of the major protein P24. They have 55 additional amino acids at the amino-terminal part which are coded by the pre-S region of the viral DNA. ...

journal_title：Journal of virology

authors： Stibbe W,Gerlich WH

更新日期：1983-05-01 00:00:00

abstract：:Herpesviruses are important pathogens of humans and other animals. Herpesvirus infectious clones that can reconstitute phenotypically wild-type (wt) virus are extremely valuable tools for elucidating the roles of specific genes in virus pathophysiology as well as for making vaccines. Ictalurid herpesvirus 1 (channel c...

journal_title：Journal of virology

authors： Kunec D,Hanson LA,van Haren S,Nieuwenhuizen IF,Burgess SC

更新日期：2008-04-01 00:00:00

abstract：:Hepatitis delta antigen (HDAg) is the only known protein of hepatitis delta virus and was previously shown to localize in the nucleoplasm of infected liver cells. In this study, nuclear localization signals of HDAg were defined by expressing various domains of the antigen in both hepatic and nonhepatic cells as beta-g...

journal_title：Journal of virology

authors： Chang MF,Chang SC,Chang CI,Wu K,Kang HY

更新日期：1992-10-01 00:00:00

abstract：:Human papillomaviruses (HPV) link their life cycles to epithelial differentiation and induce productive replication of viral DNA in suprabasal cells. Viral-DNA amplification requires cells to remain active in the cell cycle upon differentiation. This is in contrast to normal cells, which lose proliferative capability ...

journal_title：Journal of virology

authors： Melar-New M,Laimins LA

更新日期：2010-05-01 00:00:00

abstract：:During primary varicella-zoster virus (VZV) infection, it is presumed that virus is transmitted from mucosal sites to regional lymph nodes, where T cells become infected. The cell type responsible for VZV transport from the mucosa to the lymph nodes has not been defined. In this study, we assessed the susceptibility o...

journal_title：Journal of virology

authors： Abendroth A,Morrow G,Cunningham AL,Slobedman B

更新日期：2001-07-01 00:00:00

abstract：:Fluorosulfonylbenzoyl 5'-adenosine (FSBA) bound to one site in simian virus 40 large T antigen (T) and covalently modified greater than 95% of the molecules in a complete reaction. This analog for ATP specifically cross-links to the Mg-phosphate pocket in ATP-binding sites. Cyanogen bromide cleavage and tryptic digest...

journal_title：Journal of virology

authors： Bradley MK

更新日期：1990-10-01 00:00:00

abstract：:The development of antiviral drug resistance is an important problem in the treatment of human immunodeficiency virus type 1 (HIV-1) infection. Potent antiretroviral therapy is currently used for treatment, and typically consists of at least two reverse transcriptase (RT) inhibitors. We have previously reported that b...

journal_title：Journal of virology

authors： Chen R,Yokoyama M,Sato H,Reilly C,Mansky LM

更新日期：2005-09-01 00:00:00