Enzymatic radioiodination of the envelope proteins of avian myeloblastosis virus.

abstract：:Vesicular stomatitis virus (VSV) is a prototype nonsegmented, negative-sense virus used to examine viral functions of a broad family of viruses, including human pathogens. Here we demonstrate that S(2) VSV, an isolate with a small plaque phenotype compared to other Indiana strain viruses, has a transcription defect re...

journal_title：Journal of virology

authors： Hodges EN,Heinrich BS,Connor JH

更新日期：2012-08-01 00:00:00

abstract：:The matrix (M) protein of vesicular stomatitis virus (VSV) is a potent inhibitor in vivo of transcription by all three host RNA polymerases (RNAP). In the case of host RNA polymerase II (RNAPII), the inhibition is due to lack of activity of the TATA-binding protein (TBP), which is a subunit of the basal transcription ...

journal_title：Journal of virology

authors： Yuan H,Puckett S,Lyles DS

更新日期：2001-05-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of PRRS, which has important impacts on the pig industry. PRRSV infection results in disruption of the swine leukocyte antigen class I (SLA-I) antigen presentation pathway. In this study, highly pathogenic PRRSV (HP-PRRSV) infection inh...

journal_title：Journal of virology

authors： Qi P,Liu K,Wei J,Li Y,Li B,Shao D,Wu Z,Shi Y,Tong G,Qiu Y,Ma Z

更新日期：2017-02-14 00:00:00

abstract：:Herpes simplex virus 1 (HSV-1) genomes are associated with the repressive heterochromatic marks H3K9me2/me3 and H3K27me3 during latency. Previous studies have demonstrated that inhibitors of H3K9me2/me3 histone demethylases reduce the ability of HSV-1 to reactivate from latency. Here we demonstrate that GSK-J4, a spec...

journal_title：Journal of virology

authors： Messer HG,Jacobs D,Dhummakupt A,Bloom DC

更新日期：2015-03-01 00:00:00

abstract：:The human foamy virus (HFV) contains within the U3 region of its long terminal repeat (LTR) three perfect consensus sequences for the binding of the inducible transcription factor AP-1. Results of DNase I footprint protection and gel retardation assays demonstrated that proteins in extracts of HeLa and BHK-21 cells as...

journal_title：Journal of virology

authors： Maurer B,Serfling E,ter Meulen V,Rethwilm A

更新日期：1991-11-01 00:00:00

abstract：:Host-virus interactions control disease progression in human immunodeficiency virus-infected human beings and in nonhuman primates infected with simian or simian/human immunodeficiency viruses (SHIV). These interactions evolve rapidly during acute infection and are key to the mechanisms of viral persistence and AIDS. ...

journal_title：Journal of virology

authors： Wallace M,Waterman PM,Mitchen JL,Djavani M,Brown C,Trivedi P,Horejsh D,Dykhuizen M,Kitabwalla M,Pauza CD

更新日期：1999-12-01 00:00:00

abstract：:Changes in T-cell function are a hallmark of human immunodeficiency virus type 1 (HIV-1) infection, but the pathogenic mechanisms leading to these changes are unclear. We examined the gene expression profiles in ex vivo human CD4+ and CD8+ T cells from untreated HIV-1-infected individuals at different clinical stages ...

journal_title：Journal of virology

authors： Hyrcza MD,Kovacs C,Loutfy M,Halpenny R,Heisler L,Yang S,Wilkins O,Ostrowski M,Der SD

更新日期：2007-04-01 00:00:00

abstract：:The Vif protein of human immunodeficiency virus type 1 (HIV-1) is important for virion infectivity. Previous studies have shown that vif-defective virions exhibit structural abnormalities in the virus core and are defective in the ability to complete proviral DNA synthesis in acutely infected cells. We developed novel...

journal_title：Journal of virology

authors： Ohagen A,Gabuzda D

更新日期：2000-12-01 00:00:00

abstract：:We have developed a complementation assay, using transiently transfected COS cells, to facilitate a molecular analysis of the herpes simplex virus type 1 glycoprotein gH. When infected by a gH-null syncytial virus, COS cells expressing wild-type gH generate infectious progeny virions and form a syncytium with neighbor...

journal_title：Journal of virology

authors： Wilson DW,Davis-Poynter N,Minson AC

更新日期：1994-11-01 00:00:00

abstract：:Reovirus encephalitis in mice was used as a model system to investigate astrocyte activation (astrogliosis) following viral infection of the brain. Reovirus infection resulted in astrogliosis, as evidenced by increased expression of glial fibrillary acidic protein (GFAP), and the upregulation of genes that have been p...

journal_title：Journal of virology

authors： Clarke P,Zhuang Y,Berens HM,Leser JS,Tyler KL

更新日期：2019-05-01 00:00:00

abstract：:The inclusion of Mimiviridae members in the putative monophyletic nucleocytoplasmic large DNA virus (NCLDV) group is based on genomic and phylogenomic patterns. This shows that, along with other viral families, they share a set of genes known as core or "hallmark genes," including the gene for the major capsid protein...

journal_title：Journal of virology

authors： Boratto PVM,Dornas FP,da Silva LCF,Rodrigues RAL,Oliveira GP,Cortines JR,Drumond BP,Abrahão JS

更新日期：2018-01-02 00:00:00

abstract：:Reverse transcription in hepatitis B viruses is initiated through a unique protein priming mechanism whereby the viral reverse transcriptase (RT) first assembles into a ribonucleoprotein (RNP) complex with its RNA template and then initiates DNA synthesis de novo using the RT itself as a protein primer. RNP formation ...

journal_title：Journal of virology

authors： Hu J,Anselmo D

更新日期：2000-12-01 00:00:00

abstract：:The human airway epithelium (HAE) represents the entry port of many human respiratory viruses, including human coronaviruses (HCoVs). Nowadays, four HCoVs, HCoV-229E, HCoV-OC43, HCoV-HKU1, and HCoV-NL63, are known to be circulating worldwide, causing upper and lower respiratory tract infections in nonhospitalized and ...

journal_title：Journal of virology

authors： Dijkman R,Jebbink MF,Koekkoek SM,Deijs M,Jónsdóttir HR,Molenkamp R,Ieven M,Goossens H,Thiel V,van der Hoek L

更新日期：2013-06-01 00:00:00

abstract：:DBA/2 mice carry a single endogenous ecotropic murine leukemia provirus designated Emv-3. Although this provirus appears to be nondefective by genomic restriction enzyme mapping, weanling mice do not produce virus and only about one-third of adult mice ever express virus. 5-Iododeoxyuridine and 5-azacytidine, two pote...

journal_title：Journal of virology

authors： Copeland NG,Jenkins NA,Nexø B,Schultz AM,Rein A,Mikkelsen T,Jørgensen P

更新日期：1988-02-01 00:00:00

abstract：:Bovine leukemia virus (BLV) from either persistently infected bat cells or fetal lamb kidney cells induced rapid syncytium formation in F81 indicator cells. Distinct syncytia were seen within 2 h after inoculation of cells with highly concentrated (500-fold) cell-free BLV preparations and within 4 to 8 h when unconcen...

journal_title：Journal of virology

authors： Graves DC,Jones LV

更新日期：1981-06-01 00:00:00

abstract：:The interaction of papillomavirus E2 proteins with cellular Brd4 protein is important for transcriptional regulation of viral genes and partitioning of viral genomes. Bovine papillomavirus type 1 (BPV-1) E2 binds cellular chromatin in complex with Brd4 in both mitotic and interphase cells. To identify specific sites o...

journal_title：Journal of virology

authors： Jang MK,Kwon D,McBride AA

更新日期：2009-03-01 00:00:00

abstract：:During Epstein-Barr virus (EBV) latent infection of B lymphocytes in vitro, six EBV nuclear antigens (EBNAs) are expressed from one of two promoters, Cp and Wp, whose activities are mutually exclusive. Upon infection, Wp is initially active, followed by a switch to Cp for the duration of latency. In this study, the im...

journal_title：Journal of virology

authors： Puglielli MT,Desai N,Speck SH

更新日期：1997-01-01 00:00:00

abstract：:Chick embryo cells became more sensitive to the action of interferon the longer they remained in culture. This phenomenon was found even before confluency had been reached. The relative insensitivity of newly seeded cells was not due to a loss of receptors. Cells synthesizing deoxyribonucleic acid (DNA) at a high rate...

journal_title：Journal of virology

authors： Rossman TG,Vilcek J

更新日期：1969-07-01 00:00:00

abstract：:A pediatric human immunodeficiency virus type 1 (HIV-1) vaccine would be desirable to protect infants against HIV-1 transmission from breast-feeding. Such a vaccine would need to induce protective immunity at mucosal surfaces in neonates as soon as possible after birth. Recombinant adenovirus (rAd) vectors have been s...

journal_title：Journal of virology

authors： Liu J,Li H,Iampietro MJ,Barouch DH

更新日期：2012-08-01 00:00:00

abstract：:The virion host shutoff protein (vhs) of herpes simplex virus (HSV) triggers global shutoff of host protein synthesis and accelerated mRNA turnover during virus infection and induces endoribonucleolytic cleavage of exogenous RNA substrates when it is produced in a rabbit reticulocyte (RRL) in vitro translation system....

journal_title：Journal of virology

authors： Lu P,Jones FE,Saffran HA,Smiley JR

更新日期：2001-02-01 00:00:00

abstract：:Koi herpesvirus (KHV) is the causative agent of a lethal disease in koi and common carp. In the present study, we describe the cloning of the KHV genome as a stable and infectious bacterial artificial chromosome (BAC) clone that can be used to produce KHV recombinant strains. This goal was achieved by the insertion of...

journal_title：Journal of virology

authors： Costes B,Fournier G,Michel B,Delforge C,Raj VS,Dewals B,Gillet L,Drion P,Body A,Schynts F,Lieffrig F,Vanderplasschen A

更新日期：2008-05-01 00:00:00

abstract：:Sindbis virus was iodinated by using the enzyme lactoperoxidase, an iodination technique which labels only surface proteins. By this technique, the two viral glycoproteins are labeled, and the internal viral protein is not. The two glycoproteins are iodinated to strikingly different extents. This difference in suscept...

journal_title：Journal of virology

authors： Sefton BM,Wickus GG,Burge BW

更新日期：1973-05-01 00:00:00

abstract：:The genome of all densoviruses (DNVs) so far isolated from mosquitoes or mosquito cell lines consists of a 4-kb single-stranded DNA molecule with a monosense organization (genus Brevidensovirus, subfamily Densovirinae). We previously reported the isolation of a Culex pipiens DNV (CpDNV) that differs significantly from...

journal_title：Journal of virology

authors： Baquerizo-Audiot E,Abd-Alla A,Jousset FX,Cousserans F,Tijssen P,Bergoin M

更新日期：2009-07-01 00:00:00

abstract：:Ribonucleic acid extracted from influenza virus was labeled at the 3' termini with (3)H and analyzed by polyacrylamide gel electrophoresis. Influenza virus was found to contain a minimum of seven and possibly as many as 10 polynucleotide chains, most of which appear to terminate at the 3' end in uridine. ...

journal_title：Journal of virology

authors： Lewandowski LJ,Content J,Leppla SH

更新日期：1971-11-01 00:00:00

abstract：:L2 cells infected with vesicular stomatitis virus under single-cycle conditions have been studied by scanning electron microscopy after preparation by the critical point drying technique. Three dimensional images of intact cells show bullet-shaped vesicular stomatitis virus virions budding singly and in radiating clus...

journal_title：Journal of virology

authors： Holmes KV

更新日期：1975-02-01 00:00:00

abstract：:Dengue virus (DENV) and hepatitis C virus (HCV), members of the family Flaviviridae, are global human health concerns. As positive-strand RNA viruses, they each replicate in the cytoplasm of infected cells and induce distinct membranous replication compartments where most, if not all, steps of the viral life cycle occ...

journal_title：Journal of virology

authors： Chatel-Chaix L,Bartenschlager R

更新日期：2014-06-01 00:00:00

abstract：:Avian influenza A viruses, such as the highly pathogenic avian H5N1 viruses, sporadically enter the human population but often do not transmit between individuals. In rare cases, however, they establish a new lineage in humans. In addition to well-characterized barriers to cell entry, one major hurdle which avian viru...

journal_title：Journal of virology

authors： Mänz B,Schwemmle M,Brunotte L

更新日期：2013-07-01 00:00:00

abstract：UNLABELLED:Demonstrating direct interactions between host and virus proteins during infection is a major goal and challenge for the field of virology. Most protein interactions are not binary or easily amenable to structural determination. Using infectious preparations of a polerovirus (Potato leafroll virus [PLRV]) an...

journal_title：Journal of virology

authors： DeBlasio SL,Chavez JD,Alexander MM,Ramsey J,Eng JK,Mahoney J,Gray SM,Bruce JE,Cilia M

更新日期：2015-12-09 00:00:00

abstract：:Herpesviruses are members of a diverse family of viruses that colonize all vertebrates from fish to mammals. Although more than one hundred herpesviruses exist, all are nearly identical architecturally, with a genome consisting of a linear double-stranded DNA molecule (100 to 225 kbp) protected by an icosahedral capsi...

journal_title：Journal of virology

authors： Morissette G,Flamand L

更新日期：2010-12-01 00:00:00

abstract：UNLABELLED:SSV-type integrases, encoded by fuselloviruses which infect the hyperthermophilic archaea of the Sulfolobales, are archaeal members of the tyrosine recombinase family. These integrases catalyze viral integration into and excision from a specific site on the host genome. In the present study, we have establis...

journal_title：Journal of virology

authors： Zhan Z,Zhou J,Huang L

更新日期：2015-11-01 00:00:00