HEAT SHOCK FACTOR A8a Modulates Flavonoid Synthesis and Drought Tolerance.

Abstract:

:Drought is an important environmental factor affecting the growth and production of agricultural crops and fruits worldwide, including apple (Malus domestica). Heat shock factors (HSFs) have well-documented functions in stress responses, but their roles in flavonoid synthesis and the flavonoid-mediated drought response mechanism remain elusive. In this study, we demonstrated that a drought-responsive HSF, designated MdHSFA8a, promotes the accumulation of flavonoids, scavenging of reactive oxygen species, and plant survival under drought conditions. A chaperone, HEAT SHOCK PROTEIN90 (HSP90), interacted with MdHSFA8a to inhibit its binding activity and transcriptional activation. However, under drought stress, the MdHSP90-MdHSFA8a complex dissociated and the released MdHSFA8a further interacted with the APETALA2/ETHYLENE RESPONSIVE FACTOR family transcription factor RELATED TO AP2.12 to activate downstream gene activity. In addition, we demonstrated that MdHSFA8a participates in abscisic acid-induced stomatal closure and promotes the expression of abscisic acid signaling-related genes. Collectively, these findings provide insight into the mechanism by which stress-inducible MdHSFA8a modulates flavonoid synthesis to regulate drought tolerance.

journal_name

Plant Physiol

journal_title

Plant physiology

authors

Wang N,Liu W,Yu L,Guo Z,Chen Z,Jiang S,Xu H,Fang H,Wang Y,Zhang Z,Chen X

doi

10.1104/pp.20.01106

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

1273-1290

issue

3

eissn

0032-0889

issn

1532-2548

pii

pp.20.01106

journal_volume

184

pub_type

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