Platform for micro-invasive membrane-free biochemical sampling of brain interstitial fluid.

abstract：:Massive declines in population abundances of marine animals have been documented over century-long time scales. However, analogous loss of spatial extent of habitat-forming organisms is less well known because georeferenced data are rare over long time scales, particularly in subtidal, tropical marine regions. We use ...

journal_title：Science advances

authors： McClenachan L,O'Connor G,Neal BP,Pandolfi JM,Jackson JBC

更新日期：2017-09-06 00:00:00

abstract：:In retinal detachment (RD), photoreceptor death and permanent vision loss are caused by neurosensory retina separating from the retinal pigment epithelium because of subretinal fluid (SRF), and successful surgical reattachment is not predictive of total visual recovery. As retinal iron overload exacerbates cell death ...

journal_title：Science advances

authors： Daruich A,Le Rouzic Q,Jonet L,Naud MC,Kowalczuk L,Pournaras JA,Boatright JH,Thomas A,Turck N,Moulin A,Behar-Cohen F,Picard E

更新日期：2019-01-09 00:00:00

abstract：:The Mott transition-a metal-insulator transition caused by repulsive Coulomb interactions between electrons-is a central issue in condensed matter physics because it is the mother earth of various attractive phenomena. Outstanding examples are high-Tc (critical temperature) cuprates and manganites exhibiting colossal ...

journal_title：Science advances

authors： Itou T,Watanabe E,Maegawa S,Tajima A,Tajima N,Kubo K,Kato R,Kanoda K

更新日期：2017-08-11 00:00:00

abstract：:A sulfide-oxidizing microorganism, Desulfurivibrio alkaliphilus (DA), generates a consistent enrichment of sulfur-34 (34S) in the produced sulfate of +12.5 per mil or greater. This observation challenges the general consensus that the microbial oxidation of sulfide does not result in large 34S enrichments and suggests...

journal_title：Science advances

authors： Pellerin A,Antler G,Holm SA,Findlay AJ,Crockford PW,Turchyn AV,Jørgensen BB,Finster K

更新日期：2019-07-24 00:00:00

abstract：:Wächtershäuser's proposal of the autotrophic origin of life theory and subsequent laboratory demonstrations of relevant organic reactions have opened a new gate for the exploration of the origin of life. However, this scenario remains controversial because, at present, it requires a high pressure of CO as a source of ...

journal_title：Science advances

authors： Kitadai N,Nakamura R,Yamamoto M,Takai K,Li Y,Yamaguchi A,Gilbert A,Ueno Y,Yoshida N,Oono Y

更新日期：2018-04-04 00:00:00

abstract：:The tetrapod neuronal protein ARC and its Drosophila melanogaster homolog, dARC1, have important but differing roles in neuronal development. Both are thought to originate through exaptation of ancient Ty3/Gypsy retrotransposon Gag, with their novel function relying on an original capacity for self-assembly and encaps...

journal_title：Science advances

authors： Cottee MA,Letham SC,Young GR,Stoye JP,Taylor IA

更新日期：2020-01-01 00:00:00

abstract：:Poor transport of neuropharmaceutics through central nervous system (CNS) barriers limits the development of effective treatments for CNS disorders. We present the facile synthesis of a novel neuroinflammation-targeting polyethylene glycol-based dendrimer (PEGOL-60) using an efficient click chemistry approach. PEGOL-6...

journal_title：Science advances

authors： Sharma A,Sharma R,Zhang Z,Liaw K,Kambhampati SP,Porterfield JE,Lin KC,DeRidder LB,Kannan S,Kannan RM

更新日期：2020-01-22 00:00:00

abstract：:A growing body of empirical evidence is revealing the value of nature experience for mental health. With rapid urbanization and declines in human contact with nature globally, crucial decisions must be made about how to preserve and enhance opportunities for nature experience. Here, we first provide points of consensu...

journal_title：Science advances

authors： Bratman GN,Anderson CB,Berman MG,Cochran B,de Vries S,Flanders J,Folke C,Frumkin H,Gross JJ,Hartig T,Kahn PH Jr,Kuo M,Lawler JJ,Levin PS,Lindahl T,Meyer-Lindenberg A,Mitchell R,Ouyang Z,Roe J,Scarlett L,Smith JR,

更新日期：2019-07-24 00:00:00

abstract：:Gravel-bed river floodplains in mountain landscapes disproportionately concentrate diverse habitats, nutrient cycling, productivity of biota, and species interactions. Although stream ecologists know that river channel and floodplain habitats used by aquatic organisms are maintained by hydrologic regimes that mobilize...

journal_title：Science advances

authors： Hauer FR,Locke H,Dreitz VJ,Hebblewhite M,Lowe WH,Muhlfeld CC,Nelson CR,Proctor MF,Rood SB

更新日期：2016-06-24 00:00:00

abstract：:Glass-forming ability (GFA) is the ability of a liquid to avoid crystallization during cooling. Metal-organic frameworks (MOFs) are a new class of glass formers (1-3), with hitherto unknown dynamic and thermodynamic properties. We report the discovery of a new series of tetrahedral glass systems, zeolitic imidazolate ...

journal_title：Science advances

authors： Qiao A,Bennett TD,Tao H,Krajnc A,Mali G,Doherty CM,Thornton AW,Mauro JC,Greaves GN,Yue Y

更新日期：2018-03-09 00:00:00

abstract：:Bacterial chemotaxis-a fundamental example of directional navigation in the living world-is key to many biological processes, including the spreading of bacterial infections. Many bacterial species were recently reported to exhibit several distinct swimming modes-the flagella may, for example, push the cell body or wr...

journal_title：Science advances

authors： Alirezaeizanjani Z,Großmann R,Pfeifer V,Hintsche M,Beta C

更新日期：2020-05-27 00:00:00

abstract：:Solar-thermal desalination (STD) is a potentially low-cost, sustainable approach for providing high-quality fresh water in the absence of water and energy infrastructures. Despite recent efforts to advance STD by improving heat-absorbing materials and system designs, the best strategies for maximizing STD performance ...

journal_title：Science advances

authors： Wang Z,Horseman T,Straub AP,Yip NY,Li D,Elimelech M,Lin S

更新日期：2019-07-26 00:00:00

abstract：:Can mating influence cognitive functions such as learning and memory in a permanent way? We have addressed this question using a combined behavioral and in vivo imaging approach, finding that aversive long-term memory performance strongly increases in Drosophila females in response to sperm transfer following mating. ...

journal_title：Science advances

authors： Scheunemann L,Lampin-Saint-Amaux A,Schor J,Preat T

更新日期：2019-11-20 00:00:00

abstract：:Predator-prey interactions revealed by vertebrate trace fossils are extremely rare. We present footprint evidence from White Sands National Monument in New Mexico for the association of sloth and human trackways. Geologically, the sloth and human trackways were made contemporaneously, and the sloth trackways show evid...

journal_title：Science advances

authors： Bustos D,Jakeway J,Urban TM,Holliday VT,Fenerty B,Raichlen DA,Budka M,Reynolds SC,Allen BD,Love DW,Santucci VL,Odess D,Willey P,McDonald HG,Bennett MR

更新日期：2018-04-25 00:00:00

abstract：:The pathways and transformations of dense water overflows, which depend on small-scale interactions between flow dynamics and erosional-depositional processes, are a central piece in the ocean's large-scale circulation. A novel, high-resolution current and hydrographic data set highlights the intricate pathway travell...

journal_title：Science advances

authors： Sánchez-Leal RF,Bellanco MJ,Fernández-Salas LM,García-Lafuente J,Gasser-Rubinat M,González-Pola C,Hernández-Molina FJ,Pelegrí JL,Peliz A,Relvas P,Roque D,Ruiz-Villarreal M,Sammartino S,Sánchez-Garrido JC

更新日期：2017-11-15 00:00:00

abstract：:Selective nerve transfers surgically rewire motor neurons and are used in extremity reconstruction to restore muscle function or to facilitate intuitive prosthetic control. We investigated the neurophysiological effects of rewiring motor axons originating from spinal motor neuron pools into target muscles with lower i...

journal_title：Science advances

authors： Bergmeister KD,Aman M,Muceli S,Vujaklija I,Manzano-Szalai K,Unger E,Byrne RA,Scheinecker C,Riedl O,Salminger S,Frommlet F,Borschel GH,Farina D,Aszmann OC

更新日期：2019-01-02 00:00:00

abstract：:Nanomaterials often surprise us with unexpected phenomena. Here, we report a discovery of the anti-twinning deformation, previously thought impossible, in nanoscale body-centered cubic (BCC) tungsten crystals. By conducting in situ transmission electron microscopy nanomechanical testing, we observed the nucleation and...

journal_title：Science advances

authors： Wang J,Zeng Z,Wen M,Wang Q,Chen D,Zhang Y,Wang P,Wang H,Zhang Z,Mao SX,Zhu T

更新日期：2020-06-03 00:00:00

abstract：:Climatic conditions shift gradually over millennia, altering the rates at which carbon (C) is fixed from the atmosphere and stored in the soil. However, legacy impacts of past climates on current soil C stocks are poorly understood. We used data from more than 5000 terrestrial sites from three global and regional data...

journal_title：Science advances

authors： Delgado-Baquerizo M,Eldridge DJ,Maestre FT,Karunaratne SB,Trivedi P,Reich PB,Singh BK

更新日期：2017-04-12 00:00:00

abstract：:Optogenetics is a paradigm-changing new method to study and manipulate the behavior of cells with light. Following major advances of the used genetic constructs over the last decade, the light sources required for optogenetic control are now receiving increased attention. We report a novel optogenetic illumination pla...

journal_title：Science advances

authors： Steude A,Witts EC,Miles GB,Gather MC

更新日期：2016-05-06 00:00:00

abstract：:We present an ab initio computational approach for the calculation of resonant Raman intensities, including both excitonic and nonadiabatic effects. Our diagrammatic approach, which we apply to two prototype, semiconducting layered materials, allows a detailed analysis of the impact of phonon-mediated exciton-exciton ...

journal_title：Science advances

authors： Reichardt S,Wirtz L

更新日期：2020-08-07 00:00:00

abstract：:Characterizing and understanding the emergence of multiple macroscopically ordered electronic phases through subtle tuning of temperature, pressure, and chemical doping has been a long-standing central issue for complex materials research. We report the first comprehensive studies of optical doping-induced emergence o...

journal_title：Science advances

authors： Han TR,Zhou F,Malliakas CD,Duxbury PM,Mahanti SD,Kanatzidis MG,Ruan CY

更新日期：2015-06-26 00:00:00

abstract：:Predicted changes in the intensity and frequency of climate extremes urge a better mechanistic understanding of the stress response of microbially mediated carbon (C) and nutrient cycling processes. We analyzed the resistance and resilience of microbial C, nitrogen (N), and phosphorus (P) cycling processes and microbi...

journal_title：Science advances

authors： Mooshammer M,Hofhansl F,Frank AH,Wanek W,Hämmerle I,Leitner S,Schnecker J,Wild B,Watzka M,Keiblinger KM,Zechmeister-Boltenstern S,Richter A

更新日期：2017-05-03 00:00:00

abstract：:Porous membranes with ultrafast ion permeation and high ion selectivity are highly desirable for efficient mineral separation, water purification, and energy conversion, but it is still a huge challenge to efficiently separate monatomic ions of the same valence and similar sizes using synthetic membranes. We report me...

journal_title：Science advances

authors： Zhang H,Hou J,Hu Y,Wang P,Ou R,Jiang L,Liu JZ,Freeman BD,Hill AJ,Wang H

更新日期：2018-02-09 00:00:00

abstract：:Intrinsic immune defenses mediated by restriction factors inhibit productive viral infections. Select viruses rapidly establish latent infections and, with gene expression profiles that imply cell-autonomous intrinsic defenses, may be the most effective immune control measure against latent reservoirs. We illustrate t...

journal_title：Science advances

authors： Lee SH,Albright ER,Lee JH,Jacobs D,Kalejta RF

更新日期：2015-11-27 00:00:00

abstract：:Ciliary oscillations driven by molecular motors cause fluid motion at micron scale. Stable oscillations require a substantial source of dissipation to balance the energy input of motors. Conventionally, it stems from external fluid. We show, in contrast, that external fluid friction is negligible compared to internal ...

journal_title：Science advances

authors： Mondal D,Adhikari R,Sharma P

更新日期：2020-08-12 00:00:00

abstract：:Fluid catalytic cracking (FCC) particles account for 40 to 45% of worldwide gasoline production. The hierarchical complex particle pore structure allows access of long-chain feedstock molecules into active catalyst domains where they are cracked into smaller, more valuable hydrocarbon products (for example, gasoline)....

journal_title：Science advances

authors： Meirer F,Kalirai S,Morris D,Soparawalla S,Liu Y,Mesu G,Andrews JC,Weckhuysen BM

更新日期：2015-04-03 00:00:00

abstract：:Nanoparticles have been extensively used for inflammation imaging and photodynamic therapy of cancer. However, the major translational barriers to most nanoparticle-based imaging and therapy applications are the limited depth of tissue penetration, inevitable requirement of external irradiation, and poor biocompatibil...

journal_title：Science advances

authors： Xu X,An H,Zhang D,Tao H,Dou Y,Li X,Huang J,Zhang J

更新日期：2019-01-09 00:00:00

abstract：:In traditional models of heteroepitaxy, the substrate serves mainly as a crystalline template for the thin-film lattice, dictating the initial roughness of the film and the degree of coherent strain. Here, performing in situ surface x-ray diffraction during the heteroepitaxial growth of LaTiO3 on SrTiO3 (001), we find...

journal_title：Science advances

authors： Cook S,Letchworth-Weaver K,Tung IC,Andersen TK,Hong H,Marks LD,Fong DD

更新日期：2019-04-12 00:00:00

abstract：:Since its first discovery in 2004, graphene has been found to host a plethora of unusual electronic transport phenomena, making it a fascinating system for fundamental studies in condensed matter physics as well as offering tremendous opportunities for future electronic and sensing devices. Typically, electronic trans...

journal_title：Science advances

authors： Tetienne JP,Dontschuk N,Broadway DA,Stacey A,Simpson DA,Hollenberg LCL

更新日期：2017-04-26 00:00:00

abstract：:The spin-polarized surface states of topological insulators (TIs) are attractive for applications in spintronics and quantum computing. A central challenge with these materials is to reliably tune the chemical potential of their electrons with respect to the Dirac point and the bulk bands. We demonstrate persistent, b...

journal_title：Science advances

authors： Yeats AL,Pan Y,Richardella A,Mintun PJ,Samarth N,Awschalom DD

更新日期：2015-10-09 00:00:00