Geoelectrochemical CO production: Implications for the autotrophic origin of life.

abstract：:Biodiversity loss is a social and ecological emergency, and calls have been made for the global expansion of protected areas (PAs) to tackle this crisis. It is unclear, however, where best to locate new PAs to protect biodiversity cost-effectively. To answer this question, we conducted a spatial meta-analysis by overl...

journal_title：Science advances

authors： Yang R,Cao Y,Hou S,Peng Q,Wang X,Wang F,Tseng TH,Yu L,Carver S,Convery I,Zhao Z,Shen X,Li S,Zheng Y,Liu H,Gong P,Ma K

更新日期：2020-09-09 00:00:00

abstract：:Stimulation of Escherichia coli by exponential ramps of chemoattractants generates step changes in the concentration of the response regulator, CheY-P. Because flagellar motors are ultrasensitive, this should change the fraction of time that motors spin clockwise, the CWbias. However, early work failed to show changes...

journal_title：Science advances

authors： Lele PP,Shrivastava A,Roland T,Berg HC

更新日期：2015-10-16 00:00:00

abstract：:Engineering the thermal conductivity of amorphous materials is highly essential for the thermal management of future electronic devices. Here, we demonstrate the impact of ultrafine nanostructuring on the thermal conductivity reduction of amorphous silicon nitride (a-Si3N4) thin films, in which the thermal transport i...

journal_title：Science advances

authors： Tambo N,Liao Y,Zhou C,Ashley EM,Takahashi K,Nealey PF,Naito Y,Shiomi J

更新日期：2020-09-25 00:00:00

abstract：:Coastal vertical land motion affects projections of sea-level rise, and subsidence exacerbates flooding hazards. Along the ~1350-km California coastline, records of high-resolution vertical land motion rates are scarce due to sparse instrumentation, and hazards to coastal communities are underestimated. Here, we consi...

journal_title：Science advances

authors： Blackwell E,Shirzaei M,Ojha C,Werth S

更新日期：2020-07-31 00:00:00

abstract：:A novel, thin-film platform that preserves live viruses, bacteria, antibodies, and enzymes without refrigeration for extended periods of time is described. Studies with recombinant adenovirus in an optimized formulation that supports recovery of live virus through 16 freeze-thaw cycles revealed that production of an a...

journal_title：Science advances

authors： Bajrovic I,Schafer SC,Romanovicz DK,Croyle MA

更新日期：2020-03-04 00:00:00

abstract：:N6-methyladenine (6mdA) is a widespread DNA modification in bacteria. More recently, 6mdA has also been characterized in mammalian DNA. However, measurements of 6mdA abundance and profiles are often very dissimilar between studies, even when performed on DNA from identical mammalian cell types. Using comprehensive bio...

journal_title：Science advances

authors： Douvlataniotis K,Bensberg M,Lentini A,Gylemo B,Nestor CE

更新日期：2020-03-18 00:00:00

abstract：:Nitrogen oxides (NO x ) emitted from human activities are believed to regulate the atmospheric oxidation capacity of the troposphere. However, observational evidence is limited for the low-to-median NO x concentrations prevalen...

journal_title：Science advances

authors： Liu Y,Seco R,Kim S,Guenther AB,Goldstein AH,Keutsch FN,Springston SR,Watson TB,Artaxo P,Souza RAF,McKinney KA,Martin ST

更新日期：2018-04-11 00:00:00

abstract：:Since its first discovery in 2004, graphene has been found to host a plethora of unusual electronic transport phenomena, making it a fascinating system for fundamental studies in condensed matter physics as well as offering tremendous opportunities for future electronic and sensing devices. Typically, electronic trans...

journal_title：Science advances

authors： Tetienne JP,Dontschuk N,Broadway DA,Stacey A,Simpson DA,Hollenberg LCL

更新日期：2017-04-26 00:00:00

abstract：:The homotrimeric molecular chaperone Skp of Gram-negative bacteria facilitates the transport of outer membrane proteins across the periplasm. It has been unclear how its activity is modulated during its functional cycle. Here, we report an atomic-resolution characterization of the Escherichia coli Skp monomer-trimer t...

journal_title：Science advances

authors： Mas G,Burmann BM,Sharpe T,Claudi B,Bumann D,Hiller S

更新日期：2020-10-21 00:00:00

abstract：:Spider silk fiber rapidly assembles from spidroin protein in soluble state via an incompletely understood mechanism. Here, we present an integrated model for silk formation that incorporates the effects of multiple chemical and physical gradients on the different spidroin functional domains. Central to the process is ...

journal_title：Science advances

authors： Malay AD,Suzuki T,Katashima T,Kono N,Arakawa K,Numata K

更新日期：2020-11-04 00:00:00

abstract：:The formation of the Isthmus of Panama stands as one of the greatest natural events of the Cenozoic, driving profound biotic transformations on land and in the oceans. Some recent studies suggest that the Isthmus formed many millions of years earlier than the widely recognized age of approximately 3 million years ago ...

journal_title：Science advances

authors： O'Dea A,Lessios HA,Coates AG,Eytan RI,Restrepo-Moreno SA,Cione AL,Collins LS,de Queiroz A,Farris DW,Norris RD,Stallard RF,Woodburne MO,Aguilera O,Aubry MP,Berggren WA,Budd AF,Cozzuol MA,Coppard SE,Duque-Caro H,Finne

更新日期：2016-08-17 00:00:00

abstract：:Dendritic cells (DCs) are adept at cross-presentation and initiation of antigen-specific immunity. Clinically, however, DCs produced by in vitro differentiation of monocytes in the presence of exogenous cytokines have been met with limited success. We hypothesized that DCs produced in a physiological manner may be mor...

journal_title：Science advances

authors： Han P,Hanlon D,Arshad N,Lee JS,Tatsuno K,Robinson E,Filler R,Sobolev O,Cote C,Rivera-Molina F,Toomre D,Fahmy T,Edelson R

更新日期：2020-03-11 00:00:00

abstract：:Interaction of swimming bacteria with flows controls their ability to explore complex environments, crucial to many societal and environmental challenges and relevant for microfluidic applications such as cell sorting. Combining experimental, numerical, and theoretical analysis, we present a comprehensive study of the...

journal_title：Science advances

authors： Jing G,Zöttl A,Clément É,Lindner A

更新日期：2020-07-10 00:00:00

abstract：:Altered cerebral glucose uptake is one of the hallmarks of Alzheimer's disease (AD). A dynamic glucose-enhanced (DGE) magnetic resonance imaging (MRI) approach was developed to simultaneously monitor d-glucose uptake and clearance in both brain parenchyma and cerebrospinal fluid (CSF). We observed substantially higher...

journal_title：Science advances

authors： Huang J,van Zijl PCM,Han X,Dong CM,Cheng GWY,Tse KH,Knutsson L,Chen L,Lai JHC,Wu EX,Xu J,Chan KWY

更新日期：2020-05-13 00:00:00

abstract：:Rising temperatures in the Arctic Ocean region are responsible for changes such as reduced ice cover, permafrost thawing, and increased river discharge, which, together, alter nutrient and carbon cycles over the vast Arctic continental shelf. We show that the concentration of radium-228, sourced to seawater through se...

journal_title：Science advances

authors： Kipp LE,Charette MA,Moore WS,Henderson PB,Rigor IG

更新日期：2018-01-03 00:00:00

abstract：:Mobile genetic elements, such as human endogenous retroviruses (HERVs), produce proteins that regulate brain cell functions and synaptic transmission and have been implicated in the etiology of neurological and neurodevelopmental psychiatric disorders. However, the mechanisms by which these proteins of retroviral orig...

journal_title：Science advances

authors： Johansson EM,Bouchet D,Tamouza R,Ellul P,Morr AS,Avignone E,Germi R,Leboyer M,Perron H,Groc L

更新日期：2020-07-17 00:00:00

abstract：:Active materials are capable of converting free energy into directional motion, giving rise to notable dynamical phenomena. Developing a general understanding of their structure in relation to the underlying nonequilibrium physics would provide a route toward control of their dynamic behavior and pave the way for pote...

journal_title：Science advances

authors： Kumar N,Zhang R,de Pablo JJ,Gardel ML

更新日期：2018-10-12 00:00:00

abstract：:The prenatal origins of heart disease in offspring have been established. However, research in species with developmental milestones comparable to humans is lacking, preventing translation of this knowledge to clinical contexts. Using sheep and chickens, two species with similar cardiovascular developmental milestones...

journal_title：Science advances

authors： Botting KJ,Skeffington KL,Niu Y,Allison BJ,Brain KL,Itani N,Beck C,Logan A,Murray AJ,Murphy MP,Giussani DA

更新日期：2020-08-19 00:00:00

abstract：:Oxygen isotope speleothem records exhibit coherent variability over the pan-Asian summer monsoon (AM) region. The hydroclimatic representation of these oxygen isotope records for the AM, however, has remained poorly understood. Here, combining an isotope-enabled Earth system model in transient experiments with proxy r...

journal_title：Science advances

authors： He C,Liu Z,Otto-Bliesner BL,Brady EC,Zhu C,Tomas R,Clark PU,Zhu J,Jahn A,Gu S,Zhang J,Nusbaumer J,Noone D,Cheng H,Wang Y,Yan M,Bao Y

更新日期：2021-01-22 00:00:00

abstract：:A sulfide-oxidizing microorganism, Desulfurivibrio alkaliphilus (DA), generates a consistent enrichment of sulfur-34 (34S) in the produced sulfate of +12.5 per mil or greater. This observation challenges the general consensus that the microbial oxidation of sulfide does not result in large 34S enrichments and suggests...

journal_title：Science advances

authors： Pellerin A,Antler G,Holm SA,Findlay AJ,Crockford PW,Turchyn AV,Jørgensen BB,Finster K

更新日期：2019-07-24 00:00:00

abstract：:The Paris Agreement aims to mitigate the potential impacts of climate change on ecological and social systems. Using an ensemble of climate-marine ecosystem and economic models, we explore the effects of implementing the Agreement on fish, fishers, and seafood consumers worldwide. We find that implementing the Agreeme...

journal_title：Science advances

authors： Sumaila UR,Tai TC,Lam VWY,Cheung WWL,Bailey M,Cisneros-Montemayor AM,Chen OL,Gulati SS

更新日期：2019-02-27 00:00:00

abstract：:An understanding of the normal state in the high-temperature superconducting cuprates is crucial to the ultimate understanding of the long-standing problem of the origin of the superconductivity itself. This so-called "strange metal" state is thought to be associated with a quantum critical point (QCP) hidden beneath ...

journal_title：Science advances

authors： Sarkar T,Mandal PR,Poniatowski NR,Chan MK,Greene RL

更新日期：2019-05-17 00:00:00

abstract：:Photonic crystal nanocavities, which have modal volumes of the order of a cubic wavelength in the material, are of great interest as flexible platforms for manipulating photons. Recent developments in ultra-high quality factor nanocavities with long photon lifetimes have encouraged us to develop an ultra-compact and f...

journal_title：Science advances

authors： Konoike R,Nakagawa H,Nakadai M,Asano T,Tanaka Y,Noda S

更新日期：2016-05-20 00:00:00

abstract：:Human settlement of the Caribbean represents the only example in the Americas of peoples colonizing islands that were not visible from surrounding mainland areas or other islands. Unfortunately, many interpretive models have relied on radiocarbon determinations that do not meet standard criteria for reporting because ...

journal_title：Science advances

authors： Napolitano MF,DiNapoli RJ,Stone JH,Levin MJ,Jew NP,Lane BG,O'Connor JT,Fitzpatrick SM

更新日期：2019-12-18 00:00:00

abstract：:The natural, prehuman abundance of most large predators is unknown because of the lack of historical data and a limited understanding of the natural factors that control their populations. Determining the supportable predator biomass at a given location (that is, the predator carrying capacity) would help managers to ...

journal_title：Science advances

authors： Valdivia A,Cox CE,Bruno JF

更新日期：2017-03-01 00:00:00

abstract：:Homologous recombination is exquisitely activated only during specific cell phases. In the G1 phase, homologous recombination activity is completely suppressed. According to previous reports, the activation of homologous recombination during specific cell phases depends on the kinase activity of cyclin-dependent kinas...

journal_title：Science advances

authors： Lim G,Chang Y,Huh WK

更新日期：2020-02-07 00:00:00

abstract：:Hydrogen sulfide (H2S) is a gasotransmitter and a potential therapeutic agent. However, molecular targets relevant to its therapeutic actions remain enigmatic. Sulfide-quinone oxidoreductase (SQR) irreversibly oxidizes H2S. Therefore, SQR is assumed to inhibit H2S signaling. We now report that SQR-mediated oxidation o...

journal_title：Science advances

authors： Jia J,Wang Z,Zhang M,Huang C,Song Y,Xu F,Zhang J,Li J,He M,Li Y,Ao G,Hong C,Cao Y,Chin YE,Hua ZC,Cheng J

更新日期：2020-08-26 00:00:00

abstract：:Diets rich in sugar, salt, and fat alter taste perception and food preference, contributing to obesity and metabolic disorders, but the molecular mechanisms through which this occurs are unknown. Here, we show that in response to a high sugar diet, the epigenetic regulator Polycomb Repressive Complex 2.1 (PRC2.1) pers...

journal_title：Science advances

authors： Vaziri A,Khabiri M,Genaw BT,May CE,Freddolino PL,Dus M

更新日期：2020-11-11 00:00:00

abstract：:Ammonia synthesis consumes 3 to 5% of the world's natural gas, making it a significant contributor to greenhouse gas emissions. Strategies for synthesizing ammonia that are not dependent on the energy-intensive and methane-based Haber-Bosch process are critically important for reducing global energy consumption and mi...

journal_title：Science advances

authors： Song Y,Johnson D,Peng R,Hensley DK,Bonnesen PV,Liang L,Huang J,Yang F,Zhang F,Qiao R,Baddorf AP,Tschaplinski TJ,Engle NL,Hatzell MC,Wu Z,Cullen DA,Meyer HM 3rd,Sumpter BG,Rondinone AJ

更新日期：2018-04-27 00:00:00

abstract：:We have developed a way to map brain-wide networks using focal pulsed infrared neural stimulation in ultrahigh-field magnetic resonance imaging (MRI). The patterns of connections revealed are similar to those of connections previously mapped with anatomical tract tracing methods. These include connections between cort...

journal_title：Science advances

authors： Xu AG,Qian M,Tian F,Xu B,Friedman RM,Wang J,Song X,Sun Y,Chernov MM,Cayce JM,Jansen ED,Mahadevan-Jansen A,Zhang X,Chen G,Roe AW

更新日期：2019-04-24 00:00:00