Abstract:
:Ciliary oscillations driven by molecular motors cause fluid motion at micron scale. Stable oscillations require a substantial source of dissipation to balance the energy input of motors. Conventionally, it stems from external fluid. We show, in contrast, that external fluid friction is negligible compared to internal elastic stress through a simultaneous measurement of motion and flow field of an isolated and active Chlamydomonas cilium beating near the instability threshold. Consequently, internal friction emerges as the sole source of dissipation for ciliary oscillations. We combine these experimental insights with theoretical modeling of active filaments to show that an instability to oscillations takes place when active stresses are strain softening and shear thinning. Together, our results reveal a counterintuitive mechanism of ciliary beating and provide a general experimental and theoretical methodology to analyze other active filaments, both biological and synthetic ones.
journal_name
Sci Advjournal_title
Science advancesauthors
Mondal D,Adhikari R,Sharma Pdoi
10.1126/sciadv.abb0503subject
Has Abstractpub_date
2020-08-12 00:00:00pages
eabb0503issue
33issn
2375-2548pii
abb0503journal_volume
6pub_type
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