The Mediterranean Overflow in the Gulf of Cadiz: A rugged journey.

abstract：:Large-scale modes of climate variability can force widespread crop yield anomalies and are therefore often presented as a risk to food security. We quantify how modes of climate variability contribute to crop production variance. We find that the El Niño Southern Oscillation (ENSO), the Indian Ocean Dipole (IOD), trop...

journal_title：Science advances

authors： Anderson WB,Seager R,Baethgen W,Cane M,You L

更新日期：2019-07-03 00:00:00

abstract：:Bacterial chemotaxis-a fundamental example of directional navigation in the living world-is key to many biological processes, including the spreading of bacterial infections. Many bacterial species were recently reported to exhibit several distinct swimming modes-the flagella may, for example, push the cell body or wr...

journal_title：Science advances

authors： Alirezaeizanjani Z,Großmann R,Pfeifer V,Hintsche M,Beta C

更新日期：2020-05-27 00:00:00

abstract：:The integration of structure and function for tissue engineering scaffolds is of great importance in mimicking native bone tissue. However, the complexity of hierarchical structures, the requirement for mechanical properties, and the diversity of bone resident cells are the major challenges in constructing biomimetic ...

journal_title：Science advances

authors： Zhang M,Lin R,Wang X,Xue J,Deng C,Feng C,Zhuang H,Ma J,Qin C,Wan L,Chang J,Wu C

更新日期：2020-03-20 00:00:00

abstract：:Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is an unexplained incapacitating illness that may affect up to 4 million people in the United States alone. There are no validated laboratory tests for diagnosis or management despite global efforts to find biomarkers of disease. We considered the possibility...

journal_title：Science advances

authors： Hornig M,Montoya JG,Klimas NG,Levine S,Felsenstein D,Bateman L,Peterson DL,Gottschalk CG,Schultz AF,Che X,Eddy ML,Komaroff AL,Lipkin WI

更新日期：2015-02-01 00:00:00

abstract：:SWI/SNF (switch/sucrose nonfermenting) complexes regulate transcription through chromatin remodeling and opposing gene silencing by Polycomb group (PcG) proteins. Genes encoding SWI/SNF components are critical for normal development and frequently mutated in human cancer. We characterized the in vivo contributions of ...

journal_title：Science advances

authors： van der Vaart A,Godfrey M,Portegijs V,van den Heuvel S

更新日期：2020-05-20 00:00:00

abstract：:Plants produce a myriad of taxonomically restricted specialized metabolites. This diversity-and our ability to correlate genotype with phenotype-makes the evolution of these ecologically and medicinally important compounds interesting and experimentally tractable. Trichomes of tomato and other nightshade family plants...

journal_title：Science advances

authors： Leong BJ,Lybrand DB,Lou YR,Fan P,Schilmiller AL,Last RL

更新日期：2019-04-24 00:00:00

abstract：:Quantum phenomena have the potential to speed up the solution of hard optimization problems. For example, quantum annealing, based on the quantum tunneling effect, has recently been shown to scale exponentially better with system size than classical simulated annealing. However, current realizations of quantum anneale...

journal_title：Science advances

authors： Nigg SE,Lörch N,Tiwari RP

更新日期：2017-04-07 00:00:00

abstract：:Characterizing and understanding the emergence of multiple macroscopically ordered electronic phases through subtle tuning of temperature, pressure, and chemical doping has been a long-standing central issue for complex materials research. We report the first comprehensive studies of optical doping-induced emergence o...

journal_title：Science advances

authors： Han TR,Zhou F,Malliakas CD,Duxbury PM,Mahanti SD,Kanatzidis MG,Ruan CY

更新日期：2015-06-26 00:00:00

abstract：:Mass loss from the West Antarctic ice shelves and glaciers has been linked to basal melt by ocean heat flux. The Totten Ice Shelf in East Antarctica, which buttresses a marine-based ice sheet with a volume equivalent to at least 3.5 m of global sea-level rise, also experiences rapid basal melt, but the role of ocean f...

journal_title：Science advances

authors： Rintoul SR,Silvano A,Pena-Molino B,van Wijk E,Rosenberg M,Greenbaum JS,Blankenship DD

更新日期：2016-12-16 00:00:00

abstract：:Using a cell-based assay monitoring differential protein transport in the secretory pathway coupled to high-content screening, we have identified three molecules that specifically reduce the delivery of the major co-receptor for HIV-1, CCR5, to the plasma membrane. They have no effect on the closely related receptors ...

journal_title：Science advances

authors： Boncompain G,Herit F,Tessier S,Lescure A,Del Nery E,Gestraud P,Staropoli I,Fukata Y,Fukata M,Brelot A,Niedergang F,Perez F

更新日期：2019-10-16 00:00:00

abstract：:Spatial patterns of gene expression in living organisms orchestrate cell decisions in development, homeostasis, and disease. However, most methods for reconstructing gene patterning in 3D cell culture and artificial tissues are restricted by patterning depth and scale. We introduce a depth- and scale-flexible method t...

journal_title：Science advances

authors： Corbett DC,Fabyan WB,Grigoryan B,O'Connor CE,Johansson F,Batalov I,Regier MC,DeForest CA,Miller JS,Stevens KR

更新日期：2020-09-30 00:00:00

abstract：:Understanding the remarkable excitonic effects and controlling the exciton binding energies in two-dimensional (2D) semiconductors are crucial in unlocking their full potential for use in future photonic and optoelectronic devices. Here, we demonstrate large excitonic effects and gate-tunable exciton binding energies ...

journal_title：Science advances

authors： Qiu Z,Trushin M,Fang H,Verzhbitskiy I,Gao S,Laksono E,Yang M,Lyu P,Li J,Su J,Telychko M,Watanabe K,Taniguchi T,Wu J,Neto AHC,Yang L,Eda G,Adam S,Lu J

更新日期：2019-07-19 00:00:00

abstract：:Neural organoids provide a powerful tool for investigating neural development, modeling neural diseases, screening drugs, and developing cell-based therapies. Somatic cells have previously been reprogrammed by transcription factors (TFs) into sensory ganglion (SG) neurons but not SG organoids. We identify a combinatio...

journal_title：Science advances

authors： Xiao D,Deng Q,Guo Y,Huang X,Zou M,Zhong J,Rao P,Xu Z,Liu Y,Hu Y,Shen Y,Jin K,Xiang M

更新日期：2020-05-29 00:00:00

abstract：:Since Darwin's conception of sexual selection theory, scientists have struggled to identify the evolutionary forces underlying the pervasive differences between male and female behavior, morphology, and physiology. The Darwin-Bateman paradigm predicts that anisogamy imposes stronger sexual selection on males, which, i...

journal_title：Science advances

authors： Janicke T,Häderer IK,Lajeunesse MJ,Anthes N

更新日期：2016-02-12 00:00:00

abstract：:Redox flow batteries (RFBs) are considered one of the most promising large-scale energy storage technologies. However, conventional RFBs suffer from low energy density due to the low solubility of the active materials in electrolyte. On the basis of the redox targeting reactions of battery materials, the redox flow li...

journal_title：Science advances

authors： Jia C,Pan F,Zhu YG,Huang Q,Lu L,Wang Q

更新日期：2015-11-27 00:00:00

abstract：:We examine the low-temperature states supported by the quasiperiodic host-guest structure of elemental bismuth at high pressure, Bi-III. Our electronic transport and magnetization experiments establish Bi-III as a rare example of type II superconductivity in an element, with a record upper critical field of ~ 2.5 T, u...

journal_title：Science advances

authors： Brown P,Semeniuk K,Wang D,Monserrat B,Pickard CJ,Grosche FM

更新日期：2018-04-13 00:00:00

abstract：:Band structure theory plays an essential role in exploring physics in both solid-state systems and photonics. Here, we demonstrate a direct experimental measurement of the dynamic band structure in a synthetic space including the frequency axis of light, realized in a ring resonator under near-resonant dynamic modulat...

journal_title：Science advances

authors： Li G,Zheng Y,Dutt A,Yu D,Shan Q,Liu S,Yuan L,Fan S,Chen X

更新日期：2021-01-08 00:00:00

abstract：:How mechanical forces regulate plant growth is a fascinating and long-standing question. After germination underground, buried seedlings have to dynamically adjust their growth to respond to mechanical stimulation from soil barriers. Here, we designed a lid touch assay and used atomic force microscopy to investigate t...

journal_title：Science advances

authors： Wu Q,Li Y,Lyu M,Luo Y,Shi H,Zhong S

更新日期：2020-11-27 00:00:00

abstract：:Natural genetic variation affects circadian rhythms across the evolutionary tree, but the underlying molecular mechanisms are poorly understood. We investigated population-level, molecular circadian clock variation by generating >700 tissue-specific transcriptomes of Drosophila melanogaster (w1118 ) and 141 Drosophila...

journal_title：Science advances

authors： Litovchenko M,Meireles-Filho ACA,Frochaux MV,Bevers RPJ,Prunotto A,Anduaga AM,Hollis B,Gardeux V,Braman VS,Russeil JMC,Kadener S,Dal Peraro M,Deplancke B

更新日期：2021-01-29 00:00:00

abstract：:Yearly, a quarter billion people are infected and a half a million killed by the mosquito-borne disease malaria. Lack of real-time observational tools for continuously assessing the unperturbed mosquito flight activity in situ limits progress toward improved vector control. We deployed a high-resolution entomological ...

journal_title：Science advances

authors： Brydegaard M,Jansson S,Malmqvist E,Mlacha YP,Gebru A,Okumu F,Killeen GF,Kirkeby C

更新日期：2020-05-13 00:00:00

abstract：:Among the existing elemental characterization techniques, particle-induced x-ray emission (PIXE) and energy-dispersive x-ray (EDX) spectroscopy are two of the most widely used in different scientific and technological fields. Here, we present the first quantitative laser-driven PIXE and laser-driven EDX experimental i...

journal_title：Science advances

authors： Mirani F,Maffini A,Casamichiela F,Pazzaglia A,Formenti A,Dellasega D,Russo V,Vavassori D,Bortot D,Huault M,Zeraouli G,Ospina V,Malko S,Apiñaniz JI,Pérez-Hernández JA,De Luis D,Gatti G,Volpe L,Pola A,Passoni M

更新日期：2021-01-15 00:00:00

abstract：:The Mott transition-a metal-insulator transition caused by repulsive Coulomb interactions between electrons-is a central issue in condensed matter physics because it is the mother earth of various attractive phenomena. Outstanding examples are high-Tc (critical temperature) cuprates and manganites exhibiting colossal ...

journal_title：Science advances

authors： Itou T,Watanabe E,Maegawa S,Tajima A,Tajima N,Kubo K,Kato R,Kanoda K

更新日期：2017-08-11 00:00:00

abstract：:Development of composite indicators for integrated health in populations typically relies on a priori assumptions rather than model-free, data-driven evidence. Traditional variable selection processes tend not to consider relatedness and redundancy among variables, instead considering only individual correlations. In ...

journal_title：Science advances

authors： Servadio JL,Convertino M

更新日期：2018-02-02 00:00:00

abstract：:Fractures and faults riddle the Earth's crust on all scales, and the deformation associated with them is presumed to have had significant effects on its petrological and structural evolution. However, despite the abundance of directly observable earthquake activity, unequivocal evidence for seismic slip rates along an...

journal_title：Science advances

authors： Austrheim H,Dunkel KG,Plümper O,Ildefonse B,Liu Y,Jamtveit B

更新日期：2017-02-22 00:00:00

abstract：:Nucleosynthetic isotope variability among solar system objects provides insights into the accretion history of terrestrial planets. We report on the nucleosynthetic Fe isotope composition (μ54Fe) of various meteorites and show that the only material matching the terrestrial composition is CI (Ivuna-type) carbonaceous ...

journal_title：Science advances

authors： Schiller M,Bizzarro M,Siebert J

更新日期：2020-02-12 00:00:00

abstract：:Confined to a two-dimensional plane, electrons in a strong magnetic field travel along the edge in one-dimensional quantum Hall channels that are protected against backscattering. These channels can be used as solid-state analogs of monochromatic beams of light, providing a unique platform for studying electron interf...

journal_title：Science advances

authors： Wei DS,van der Sar T,Sanchez-Yamagishi JD,Watanabe K,Taniguchi T,Jarillo-Herrero P,Halperin BI,Yacoby A

更新日期：2017-08-18 00:00:00

abstract：:Adenosine and its receptors play a key role in bone homeostasis and regeneration. Extracellular adenosine is generated from CD39 and CD73 activity in the cell membrane, through conversion of adenosine triphosphate to adenosine monophosphate (AMP) and AMP to adenosine, respectively. Despite the relevance of CD39/CD73 t...

journal_title：Science advances

authors： Shih YV,Liu M,Kwon SK,Iida M,Gong Y,Sangaj N,Varghese S

更新日期：2019-08-21 00:00:00

abstract：:The high-lying vibrational states of the magnesium dimer (Mg2), which has been recognized as an important system in studies of ultracold and collisional phenomena, have eluded experimental characterization for half a century. Until now, only the first 14 vibrational states of Mg2 have been experimentally resolved, alt...

journal_title：Science advances

authors： Yuwono SH,Magoulas I,Piecuch P

更新日期：2020-04-03 00:00:00

abstract：:Planarians exhibit traits of cephalization but are unique among bilaterians in that they ingest food by means of goal-directed movements of a trunk-positioned pharynx, following protrusion of the pharynx out of the body, raising the question of how planarians control such a complex set of body movements for achieving ...

journal_title：Science advances

authors： Miyamoto M,Hattori M,Hosoda K,Sawamoto M,Motoishi M,Hayashi T,Inoue T,Umesono Y

更新日期：2020-04-08 00:00:00

abstract：:Functionally graded materials (FGMs) enable applications in fields such as biomedicine and architecture, but their fabrication suffers from shortcomings in gradient continuity, interfacial bonding, and directional freedom. In addition, most commercial design software fail to incorporate property gradient data, hinderi...

journal_title：Science advances

authors： Giachini PAGS,Gupta SS,Wang W,Wood D,Yunusa M,Baharlou E,Sitti M,Menges A

更新日期：2020-02-21 00:00:00