Persistent optical gating of a topological insulator.

abstract：:Microbial fuel cells (MFCs) are able to directly convert about 50 to 90% of energy from oxidation of organic matters in waste to electricity and have great potential application in broad fields such as wastewater treatment. Unfortunately, the power density of the MFCs at present is significantly lower than the theoret...

journal_title：Science advances

authors： Zhao S,Li Y,Yin H,Liu Z,Luan E,Zhao F,Tang Z,Liu S

更新日期：2015-11-13 00:00:00

abstract：:Cellular cross-talk between ubiquitination and other posttranslational modifications contributes to the regulation of numerous processes. One example is ADP-ribosylation of the carboxyl terminus of ubiquitin by the E3 DTX3L/ADP-ribosyltransferase PARP9 heterodimer, but the mechanism remains elusive. Here, we show that...

journal_title：Science advances

authors： Chatrin C,Gabrielsen M,Buetow L,Nakasone MA,Ahmed SF,Sumpton D,Sibbet GJ,Smith BO,Huang DT

更新日期：2020-09-18 00:00:00

abstract：:The ability of cytosolic lipopolysaccharide (LPS) to activate caspase-11-dependent nonclassical inflammasome is intricately controlled to avoid excessive inflammatory responses. However, very little is known about the regulatory role of various metabolic pathways in the control of caspase-11 activation. Here, we demon...

journal_title：Science advances

authors： Chen R,Zeng L,Zhu S,Liu J,Zeh HJ,Kroemer G,Wang H,Billiar TR,Jiang J,Tang D,Kang R

更新日期：2019-05-22 00:00:00

abstract：:Asymmetric interactions such as entropic (e.g., encoded by nonspherical shapes) or surface forces (e.g., encoded by patterned surface chemistry or DNA hybridization) provide access to functional states of colloidal matter, but versatile approaches for engineering asymmetric van der Waals interactions have the potentia...

journal_title：Science advances

authors： Fuster HA,Wang X,Wang X,Bukusoglu E,Spagnolie SE,Abbott NL

更新日期：2020-06-19 00:00:00

abstract：:Telomerase is a ribonucleoprotein complex that catalyzes addition of telomeric DNA repeats to maintain telomeres in replicating cells. Here, we demonstrate that the telomerase protein hTERT performs an additional role at telomeres that is independent of telomerase catalytic activity yet essential for telomere integrit...

journal_title：Science advances

authors： Perera ON,Sobinoff AP,Teber ET,Harman A,Maritz MF,Yang SF,Pickett HA,Cesare AJ,Arthur JW,MacKenzie KL,Bryan TM

更新日期：2019-10-02 00:00:00

abstract：:The tendency to see life as zero-sum exacerbates political conflicts. Six studies (N = 3223) examine the relationship between political ideology and zero-sum thinking: the belief that one party's gains can only be obtained at the expense of another party's losses. We find that both liberals and conservatives view life...

journal_title：Science advances

authors： Davidai S,Ongis M

更新日期：2019-12-18 00:00:00

abstract：:Sodium/potassium-transporting adenosine triphosphatase (Na+/K+-ATPase) is one of the most abundant cell membrane proteins and is essential for eukaryotes. Endogenous negative regulators have long been postulated to play an important role in regulating the activity and stability of Na+/K+-ATPase, but characterization o...

journal_title：Science advances

authors： Chin AC,Gao Z,Riley AM,Furkert D,Wittwer C,Dutta A,Rojas T,Semenza ER,Felder RA,Pluznick JL,Jessen HJ,Fiedler D,Potter BVL,Snyder SH,Fu C

更新日期：2020-10-28 00:00:00

abstract：:Low-dimensional perovskites offer a rare opportunity to investigate lattice dynamics and charge carrier behavior in bulk quantum-confined solids, in addition to them being the leading materials in optoelectronic applications. In particular, zero-dimensional (0D) inorganic perovskites of the Cs4PbX6 (X = Cl, Br, or I) ...

journal_title：Science advances

authors： Yin J,Maity P,De Bastiani M,Dursun I,Bakr OM,Brédas JL,Mohammed OF

更新日期：2017-12-15 00:00:00

abstract：:Dynamic modulation of soft helix in terms of the molecular organization, handedness, and pitch length could result in a sophisticated control over its functions, opening numerous possibilities toward the exploration of previously unidentified applications. Here, we report a dynamic and reversible transformation of a s...

journal_title：Science advances

authors： Yuan CL,Huang W,Zheng ZG,Liu B,Bisoyi HK,Li Y,Shen D,Lu Y,Li Q

更新日期：2019-10-04 00:00:00

abstract：:The fabrication of three-dimensional (3D) objects by polymer self-assembly in solution is extremely challenging. Here, multi-tori mesostructures were obtained from the crystallization-driven self-assembly of a coil-crystalline block copolymer (BCP) in mixed solvents. The formation of these structures follows a multist...

journal_title：Science advances

authors： Guerin G,Cruz M,Yu Q

更新日期：2020-04-15 00:00:00

abstract：:We present a framework for quantifying the spatial and temporal co-occurrence of climate stresses in a nonstationary climate. We find that, globally, anthropogenic climate forcing has doubled the joint probability of years that are both warm and dry in the same location (relative to the 1961-1990 baseline). In additio...

journal_title：Science advances

authors： Sarhadi A,Ausín MC,Wiper MP,Touma D,Diffenbaugh NS

更新日期：2018-11-28 00:00:00

abstract：:Dysregulated physical stresses are generated during tumorigenesis that affect the surrounding compliant tissues including adipocytes. However, the effect of physical stressors on the behavior of adipocytes and their cross-talk with tumor cells remain elusive. Here, we demonstrate that compression of cells, resulting f...

journal_title：Science advances

authors： Li Y,Mao AS,Seo BR,Zhao X,Gupta SK,Chen M,Han YL,Shih TY,Mooney DJ,Guo M

更新日期：2020-01-22 00:00:00

abstract：:Two-dimensional (2D) layered hybrid organic-inorganic halide perovskite semiconductors form natural "multiple quantum wells" that have strong spin-orbit coupling due to the heavy elements in their building blocks. This may lead to "Rashba splitting" close to the extrema in the electron bands. We have used a plethora o...

journal_title：Science advances

authors： Zhai Y,Baniya S,Zhang C,Li J,Haney P,Sheng CX,Ehrenfreund E,Vardeny ZV

更新日期：2017-07-28 00:00:00

abstract：:Ontogenetic studies provide clues for understanding important paleobiological aspects of extinct species. When compared to that of modern humans, the adult Neanderthal thorax was shorter, deeper, and wider. This is related to the wide Neanderthal body and is consistent with their hypothetical large requirements for en...

journal_title：Science advances

authors： García-Martínez D,Bastir M,Gómez-Olivencia A,Maureille B,Golovanova L,Doronichev V,Akazawa T,Kondo O,Ishida H,Gascho D,Zollikofer CPE,de León MP,Heuzé Y

更新日期：2020-10-07 00:00:00

abstract：:It has been proposed that Mars' moons formed from a disk produced by a large impact with the planet. However, whether such an event could produce tiny Phobos and Deimos remains unclear. Using a hybrid N-body model of moon accumulation that includes a full treatment of moon-moon dynamical interactions, we first identif...

journal_title：Science advances

authors： Canup R,Salmon J

更新日期：2018-04-18 00:00:00

abstract：:Topological superconductors are exotic phases of matter featuring robust surface states that could be leveraged for topological quantum computation. A useful guiding principle for the search of topological superconductors is to relate the topological invariants with the behavior of the pairing order parameter on the n...

journal_title：Science advances

authors： Ono S,Po HC,Watanabe H

更新日期：2020-05-01 00:00:00

abstract：:The search for topological superconductors (TSCs) is one of the most urgent contemporary problems in condensed matter systems. TSCs are characterized by a full superconducting gap in the bulk and topologically protected gapless surface (or edge) states. Within each vortex core of TSCs, there exists the zero-energy Maj...

journal_title：Science advances

authors： Guan SY,Chen PJ,Chu MW,Sankar R,Chou F,Jeng HT,Chang CS,Chuang TM

更新日期：2016-11-23 00:00:00

abstract：:Transcriptional status determines the HIV replicative state in infected patients. However, the transcriptional mechanisms for proviral replication control remain unclear. In this study, we show that, apart from its function in HIV integration, LEDGF/p75 differentially regulates HIV transcription in latency and provira...

journal_title：Science advances

authors： Gao R,Bao J,Yan H,Xie L,Qin W,Ning H,Huang S,Cheng J,Zhi R,Li Z,Tucker B,Chen Y,Zhang K,Wu X,Liu Z,Gao X,Hu D

更新日期：2020-05-13 00:00:00

abstract：:Ascomycota, the largest and most well-studied phylum of fungi, contains three subphyla: Saccharomycotina (budding yeasts), Pezizomycotina (filamentous fungi), and Taphrinomycotina (fission yeasts). Despite its importance, we lack a comprehensive genome-scale phylogeny or understanding of the similarities and differenc...

journal_title：Science advances

authors： Shen XX,Steenwyk JL,LaBella AL,Opulente DA,Zhou X,Kominek J,Li Y,Groenewald M,Hittinger CT,Rokas A

更新日期：2020-11-04 00:00:00

abstract：:For natural microswimmers, the interplay of swimming activity and external flow can promote robust directed motion, for example, propulsion against (upstream rheotaxis) or perpendicular to the direction of flow. These effects are generally attributed to their complex body shapes and flagellar beat patterns. Using cata...

journal_title：Science advances

authors： Katuri J,Uspal WE,Simmchen J,Miguel-López A,Sánchez S

更新日期：2018-01-26 00:00:00

abstract：:Calcium homeostasis modulator 1 (CALHM1) is a voltage-gated ATP release channel that plays an important role in neural gustatory signaling and the pathogenesis of Alzheimer's disease. Here, we present a cryo-electron microscopy structure of full-length Ca2+-free CALHM1 from Danio rerio at an overall resolution of 3.1 ...

journal_title：Science advances

authors： Ren Y,Wen T,Xi Z,Li S,Lu J,Zhang X,Yang X,Shen Y

更新日期：2020-07-17 00:00:00

abstract：:The picture of how a gap closes in a semiconductor has been radically transformed by topological concepts. Instead of the gap closing and immediately reopening, topological arguments predict that, in the absence of inversion symmetry, a metallic phase protected by Weyl nodes persists over a finite interval of the tuni...

journal_title：Science advances

authors： Liang T,Kushwaha S,Kim J,Gibson Q,Lin J,Kioussis N,Cava RJ,Ong NP

更新日期：2017-05-31 00:00:00

abstract：:Presently, the Indian Ocean (IO) resides in a climate state that prevents strong year-to-year climate variations. This may change under greenhouse warming, but the mechanisms remain uncertain, thus limiting our ability to predict future changes in climate extremes. Using climate model simulations, we uncover the emerg...

journal_title：Science advances

authors： DiNezio PN,Puy M,Thirumalai K,Jin FF,Tierney JE

更新日期：2020-05-06 00:00:00

abstract：:Can a diverse crowd of individuals whose interests focus on distinct issues related to racial identity, class, gender, and sexuality mobilize around a shared issue? If so, how does this process work in practice? To date, limited research has explored intersectionality as a mobilization tool for social movements. This ...

journal_title：Science advances

authors： Fisher DR,Dow DM,Ray R

更新日期：2017-09-20 00:00:00

abstract：:NSF (N-ethylmaleimide-sensitive factor) and α-SNAP (α-soluble NSF attachment protein) bind to the SNARE (soluble NSF attachment protein receptor) complex, the minimum machinery to mediate membrane fusion, to form a 20S complex, which disassembles the SNARE complex for reuse. We report the cryo-EM structures of the α-S...

journal_title：Science advances

authors： Huang X,Sun S,Wang X,Fan F,Zhou Q,Lu S,Cao Y,Wang QW,Dong MQ,Yao J,Sui SF

更新日期：2019-04-10 00:00:00

abstract：:Tumor-associated macrophages (TAMs) influence lung tumor development by inducing immunosuppression. Transcriptome analysis of TAMs isolated from human lung tumor tissues revealed an up-regulation of the Wnt/β-catenin pathway. These findings were reproduced in a newly developed in vitro "trained" TAM model. Pharmacolog...

journal_title：Science advances

authors： Sarode P,Zheng X,Giotopoulou GA,Weigert A,Kuenne C,Günther S,Friedrich A,Gattenlöhner S,Stiewe T,Brüne B,Grimminger F,Stathopoulos GT,Pullamsetti SS,Seeger W,Savai R

更新日期：2020-06-05 00:00:00

abstract：:Climatic conditions shift gradually over millennia, altering the rates at which carbon (C) is fixed from the atmosphere and stored in the soil. However, legacy impacts of past climates on current soil C stocks are poorly understood. We used data from more than 5000 terrestrial sites from three global and regional data...

journal_title：Science advances

authors： Delgado-Baquerizo M,Eldridge DJ,Maestre FT,Karunaratne SB,Trivedi P,Reich PB,Singh BK

更新日期：2017-04-12 00:00:00

abstract：:The formation of the Isthmus of Panama stands as one of the greatest natural events of the Cenozoic, driving profound biotic transformations on land and in the oceans. Some recent studies suggest that the Isthmus formed many millions of years earlier than the widely recognized age of approximately 3 million years ago ...

journal_title：Science advances

authors： O'Dea A,Lessios HA,Coates AG,Eytan RI,Restrepo-Moreno SA,Cione AL,Collins LS,de Queiroz A,Farris DW,Norris RD,Stallard RF,Woodburne MO,Aguilera O,Aubry MP,Berggren WA,Budd AF,Cozzuol MA,Coppard SE,Duque-Caro H,Finne

更新日期：2016-08-17 00:00:00

abstract：:Holoprosencephaly (HPE) is a congenital forebrain defect often associated with embryonic lethality and lifelong disabilities. Currently, therapeutic and diagnostic options are limited by lack of knowledge of potential disease-causing mutations. We have identified a new mutation in the PRDM15 gene (C844Y) associated wi...

journal_title：Science advances

authors： Mzoughi S,Di Tullio F,Low DHP,Motofeanu CM,Ong SLM,Wollmann H,Wun CM,Kruszka P,Muenke M,Hildebrandt F,Dunn NR,Messerschmidt DM,Guccione E

更新日期：2020-01-10 00:00:00

abstract：:V1-ATPase is an ATP-driven rotary motor that is composed of a ring-shaped A3B3 complex and a central DF shaft. The nucleotide-free A3B3 complex of Enterococcus hirae, composed of three identical A1B1 heterodimers, showed a unique asymmetrical structure, probably due to the strong binding of the N-terminal barrel domai...

journal_title：Science advances

authors： Maruyama S,Suzuki K,Imamura M,Sasaki H,Matsunami H,Mizutani K,Saito Y,Imai FL,Ishizuka-Katsura Y,Kimura-Someya T,Shirouzu M,Uchihashi T,Ando T,Yamato I,Murata T

更新日期：2019-01-30 00:00:00