Abstract:
:We present a framework for quantifying the spatial and temporal co-occurrence of climate stresses in a nonstationary climate. We find that, globally, anthropogenic climate forcing has doubled the joint probability of years that are both warm and dry in the same location (relative to the 1961-1990 baseline). In addition, the joint probability that key crop and pasture regions simultaneously experience severely warm conditions in conjunction with dry years has also increased, including high statistical confidence that human influence has increased the probability of previously unprecedented co-occurring combinations. Further, we find that ambitious emissions mitigation, such as that in the United Nations Paris Agreement, substantially curbs increases in the probability that extremely hot years co-occur with low precipitation simultaneously in multiple regions. Our methodology can be applied to other climate variables, providing critical insight for a number of sectors that are accustomed to deploying resources based on historical probabilities.
journal_name
Sci Advjournal_title
Science advancesauthors
Sarhadi A,Ausín MC,Wiper MP,Touma D,Diffenbaugh NSdoi
10.1126/sciadv.aau3487subject
Has Abstractpub_date
2018-11-28 00:00:00pages
eaau3487issue
11issn
2375-2548pii
aau3487journal_volume
4pub_type
杂志文章相关文献
Science Advances文献大全abstract::Spider silk fiber rapidly assembles from spidroin protein in soluble state via an incompletely understood mechanism. Here, we present an integrated model for silk formation that incorporates the effects of multiple chemical and physical gradients on the different spidroin functional domains. Central to the process is ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abb6030
更新日期:2020-11-04 00:00:00
abstract::The tetrapod neuronal protein ARC and its Drosophila melanogaster homolog, dARC1, have important but differing roles in neuronal development. Both are thought to originate through exaptation of ancient Ty3/Gypsy retrotransposon Gag, with their novel function relying on an original capacity for self-assembly and encaps...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aay6354
更新日期:2020-01-01 00:00:00
abstract::High-entropy alloys exhibit exceptional mechanical properties at cryogenic temperatures, due to the activation of twinning in addition to dislocation slip. The coexistence of multiple deformation pathways raises an important question regarding how individual deformation mechanisms compete or synergize during plastic d...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aax4002
更新日期:2020-03-27 00:00:00
abstract::A growing body of empirical evidence is revealing the value of nature experience for mental health. With rapid urbanization and declines in human contact with nature globally, crucial decisions must be made about how to preserve and enhance opportunities for nature experience. Here, we first provide points of consensu...
journal_title:Science advances
pub_type: 杂志文章,评审
doi:10.1126/sciadv.aax0903
更新日期:2019-07-24 00:00:00
abstract::Neurodegeneration in mitochondrial disorders is considered irreversible because of limited metabolic plasticity in neurons, yet the cell-autonomous implications of mitochondrial dysfunction for neuronal metabolism in vivo are poorly understood. Here, we profiled the cell-specific proteome of Purkinje neurons undergoin...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aba8271
更新日期:2020-08-28 00:00:00
abstract::Rising sea levels will have overwhelmingly negative impacts on coastal communities globally. With previous research focused on how sea-level rise (SLR) affects storm-induced flooding, we show that SLR will also increase both the frequency and the intensity of tsunami-induced flooding, another significant coastal hazar...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aat1180
更新日期:2018-08-15 00:00:00
abstract::Local thermal magnetization fluctuations in Li-doped MnTe are found to increase its thermopower α strongly at temperatures up to 900 K. Below the Néel temperature (TN ~ 307 K), MnTe is antiferromagnetic, and magnon drag contributes αmd to the thermopower, which scales as ~T3. Magnon drag persists into the paramagnetic...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aat9461
更新日期:2019-09-13 00:00:00
abstract::The human bronchial epithelium is composed of multiple distinct cell types that cooperate to defend against environmental insults. While studies have shown that smoking alters bronchial epithelial function and morphology, its precise effects on specific cell types and overall tissue composition are unclear. We used si...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaw3413
更新日期:2019-12-11 00:00:00
abstract::Deep CO2 emissions characterize many nonvolcanic, seismically active regions worldwide, and the involvement of deep CO2 in the earthquake cycle is now generally recognized. However, no long-time records of such emissions have been published, and the temporal relations between earthquake occurrence and tectonic CO2 rel...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abc2938
更新日期:2020-08-26 00:00:00
abstract::Hydroxyapatite (HA) has been widely applied in bone repair because of its superior biocompatibility. Recently, a proliferation-suppressive effect of HA nanoparticles (n-HA) against various cancer cells was reported. This study was aimed at assessing the translational value of n-HA both as a bone-regenerating material ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aax6946
更新日期:2019-08-02 00:00:00
abstract::Recent research on piezoelectric materials is predominantly devoted to enhancing the piezoelectric coefficient, but overlooks its sign, largely because almost all of them exhibit positive longitudinal piezoelectricity. The only experimentally known exception is ferroelectric polymer poly(vinylidene fluoride) and its c...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aav3780
更新日期:2019-04-19 00:00:00
abstract::Developing cost-effective, active, and durable electrocatalysts is one of the most important issues for the commercialization of fuel cells. Ultrathin Pt-Mo-Ni nanowires (NWs) with a diameter of ~2.5 nm and lengths of up to several micrometers were synthesized via a H2-assisted solution route (HASR). This catalyst was...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1603068
更新日期:2017-08-30 00:00:00
abstract::Kv2.1 channels mediate cell death-enabling loss of cytosolic potassium in neurons following plasma membrane insertion at somatodendritic clusters. Overexpression of the carboxyl terminus (CT) of the cognate channel Kv2.2 is neuroprotective by disrupting Kv2.1 surface clusters. Here, we define a seven-amino acid declus...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaz8110
更新日期:2020-07-01 00:00:00
abstract::Crop diversification required to meet demands for food security and industrial use is often challenged by breeding time and amenability of varieties to genome modification. Cassava is one such crop. Grown for its large starch-rich storage roots, it serves as a staple food and a commodity in the multibillion-dollar sta...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aat6086
更新日期:2018-09-05 00:00:00
abstract::For natural microswimmers, the interplay of swimming activity and external flow can promote robust directed motion, for example, propulsion against (upstream rheotaxis) or perpendicular to the direction of flow. These effects are generally attributed to their complex body shapes and flagellar beat patterns. Using cata...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aao1755
更新日期:2018-01-26 00:00:00
abstract::Metabolic engineering uses enzymes to produce small molecules with industrial, pharmaceutical, and energy applications. However, efforts to optimize enzymatic pathways for commercial production are limited by the throughput of assays for quantifying metabolic intermediates and end products. We developed a multiplexed ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaw9180
更新日期:2019-06-05 00:00:00
abstract::Wächtershäuser's proposal of the autotrophic origin of life theory and subsequent laboratory demonstrations of relevant organic reactions have opened a new gate for the exploration of the origin of life. However, this scenario remains controversial because, at present, it requires a high pressure of CO as a source of ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aao7265
更新日期:2018-04-04 00:00:00
abstract::Genetically modified pigs for biomedical applications have been mainly generated using the somatic cell nuclear transfer technique; however, this approach requires complex micromanipulation techniques and sometimes increases the risks of both prenatal and postnatal death by faulty epigenetic reprogramming of a donor s...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1600803
更新日期:2016-09-14 00:00:00
abstract::Photonic crystal nanocavities, which have modal volumes of the order of a cubic wavelength in the material, are of great interest as flexible platforms for manipulating photons. Recent developments in ultra-high quality factor nanocavities with long photon lifetimes have encouraged us to develop an ultra-compact and f...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1501690
更新日期:2016-05-20 00:00:00
abstract::Demyelinating diseases involve loss of myelin sheaths and eventually lead to neurological problems. Unfortunately, the precise mechanisms remain unknown, and there are no effective therapies. To overcome these limitations, a reliable and physiologically relevant in vitro model is required. Here, we present a three-dim...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abd9749
更新日期:2021-01-29 00:00:00
abstract::A sulfide-oxidizing microorganism, Desulfurivibrio alkaliphilus (DA), generates a consistent enrichment of sulfur-34 (34S) in the produced sulfate of +12.5 per mil or greater. This observation challenges the general consensus that the microbial oxidation of sulfide does not result in large 34S enrichments and suggests...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaw1480
更新日期:2019-07-24 00:00:00
abstract::Bioengineered three-dimensional (3D) matrices expand our experimental repertoire to study tumor growth and progression in a biologically relevant, yet controlled, manner. Here, we used peptide amphiphiles (PAs) to coassemble with and organize extracellular matrix (ECM) proteins producing tunable 3D models of the tumor...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abb3298
更新日期:2020-10-02 00:00:00
abstract::The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function and neuronal activity are largely unexplored. Here, we established an integrated screening strategy to discover lncRNAs implicated in neurotransmitter and synaptic vesicle release. With this approach, we ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aay2670
更新日期:2019-12-18 00:00:00
abstract::We reveal an intriguing manifestation of topology, which appears in the depletion rate of topological states of matter in response to an external drive. This phenomenon is presented by analyzing the response of a generic two-dimensional (2D) Chern insulator subjected to a circular time-periodic perturbation. Because o...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1701207
更新日期:2017-08-18 00:00:00
abstract::How mechanical forces regulate plant growth is a fascinating and long-standing question. After germination underground, buried seedlings have to dynamically adjust their growth to respond to mechanical stimulation from soil barriers. Here, we designed a lid touch assay and used atomic force microscopy to investigate t...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abc9294
更新日期:2020-11-27 00:00:00
abstract::Adenosine and its receptors play a key role in bone homeostasis and regeneration. Extracellular adenosine is generated from CD39 and CD73 activity in the cell membrane, through conversion of adenosine triphosphate to adenosine monophosphate (AMP) and AMP to adenosine, respectively. Despite the relevance of CD39/CD73 t...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aax1387
更新日期:2019-08-21 00:00:00
abstract::Neurochemical dysregulation underlies many pathologies and can be monitored by measuring the composition of brain interstitial fluid (ISF). Existing in vivo tools for sampling ISF do not enable measuring large rare molecules, such as proteins and neuropeptides, and thus cannot generate a complete picture of the neuroc...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abb0657
更新日期:2020-09-25 00:00:00
abstract::Focal adjustment and zooming are universal features of cameras and advanced optical systems. Such tuning is usually performed longitudinally along the optical axis by mechanical or electrical control of focal length. However, the recent advent of ultrathin planar lenses based on metasurfaces (metalenses), which opens ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aap9957
更新日期:2018-02-23 00:00:00
abstract::Neurodegenerative disorders are caused by progressive neuronal loss, and there is no complete treatment available yet. Neuroinflammation is a common feature across neurodegenerative disorders and implicated in the progression of neurodegeneration. Dysregulated activation of microglia causes neuroinflammation and has b...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abc1428
更新日期:2020-11-13 00:00:00
abstract::Cues sent by political elites are known to influence public attitudes and behavior. Polarization in elite rhetoric may hinder effective responses to public health crises, when accurate information and rapid behavioral change can save lives. We examine polarization in cues sent to the public by current members of the U...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abc2717
更新日期:2020-07-10 00:00:00