Increased daylight availability reduces length of hospitalisation in depressive patients.

abstract：:In a recent randomized, double-blind, placebo-controlled trial, we established a robust efficacy (Cohen's d = 2.17) of osmotic release oral system-methylphenidate (OROS-methylphenidate) delivered 72 mg daily for 5 weeks versus placebo on attention deficit hyperactivity disorder (ADHD) symptoms, global severity and glo...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Ginsberg Y,Hirvikoski T,Grann M,Lindefors N

更新日期：2012-12-01 00:00:00

abstract：:Proof of efficacy of a psychotropic medicinal product is the key point of clinical psychopharmacology. This especially concerns the licensing of a new compound, but apart from this special case, lots of efficacy questions need to be answered in clinical psychopharmacology, such as, e.g. the question of the efficacy of...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Möller HJ,Broich K

更新日期：2010-02-01 00:00:00

abstract：:The present article outlines the different conception of catatonia from its initial description by Kahlbaum to current viewpoints. Originally considered to be an independent disease entity characterized by mental and motor abnormalities, catatonia was later viewed as a subtype of schizophrenia as it is the case in cur...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Pfuhlmann B,Stöber G

更新日期：2001-01-01 00:00:00

abstract：:For the functional psychoses of late life, epidemiological information comes from two sources: studies of persons who have reached psychiatric services; and surveys of elderly persons sampled from the general population. A conspectus of published data from both sources leads to the following conclusions: States phenom...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Henderson AS,Kay DW

更新日期：1997-01-01 00:00:00

abstract：:Smooth-pursuit eye-tracking performance was examined in 100 schizophrenic patients and various control groups under both attention-enhancing and attention-distracting conditions. The level of attentional demand was varied by introducing a secondary reaction time task that directed attention either toward or away from ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schlenker R,Cohen R,Berg P,Hubman W,Mohr F,Watzl H,Werther P

更新日期：1994-01-01 00:00:00

abstract：:The Trial Criteria in Schizophrenia Working Group was convened in November 2007 to define consensus criteria for clinical trials in patients suffering from acute schizophrenia with special focus on placebo-controlled trials and withdrawal conditions. Clinical trials involving patients give rise to ethical and medico-l...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Riedel M,Leucht S,Rüther E,Schmauß M,Möller HJ

更新日期：2012-03-01 00:00:00

abstract：:Working memory and information processing abnormalities are often reported in schizophrenia. The aim of this study was to examine visual backward masking (BM) functions in remitted schizophrenia-spectrum patients with spared working memory functions. Seventy-two patients with DSM-IV schizophrenia-spectrum disorders we...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kéri S,Szendi I,Kelemen O,Benedek G,Janka Z

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:The present study aims to assess the factor structure of the DSM-IV Premenstrual Dysphoric Disorder (PMDD) symptoms and its relationship with depressive symptoms. METHODS:We evaluated retrospectively PMDD symptoms in 513 female college students, through a self-reporting questionnaire based on DSM-IV criteri...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Teng CT,Filho AH,Artes R,Gorenstein C,Andrade LH,Wang YP

更新日期：2005-02-01 00:00:00

abstract：:In this review, we discuss current structural and functional imaging data on ADHD in a neurological and neuroanatomical framework. At present, the literature on adult ADHD is somewhat sparse, and so results from imaging have to therefore be considered mainly from the childhood or adolescence perspective. Most work has...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schneider M,Retz W,Coogan A,Thome J,Rösler M

更新日期：2006-09-01 00:00:00

abstract：:Compounds targeting serotonin (5-HT) are widely used as antidepressants. However, the role of 5-HT in mediating the effects of electroconvulsive seizure (ECS) therapy remains undefined. Using Tph2-/- mice depleted of brain 5-HT, we studied the effects of ECS on behavior and neurobiology. ECS significantly prolonged th...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kronenberg G,Petermann M,Dormann C,Bader M,Gass P,Hellweg R,Klempin F

更新日期：2018-12-01 00:00:00

abstract：:The impact of obsessive-compulsive symptoms on functioning in schizophrenia is still debated. This study investigated the relationship between OC symptoms and functioning along a severity gradient of obsessive-compulsive dimension. Sixty patients affected by schizophrenia completed the SCID-IV, the Positive and Negati...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tonna M,Ottoni R,Paglia F,Ossola P,De Panfilis C,Marchesi C

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:The study of familial aggregation of major mental disorders in a national population. METHOD:Within a Danish register-based cohort study, aggregation of mental disorders was analysed in all case-probands with first psychiatric contact before the age of 19 years in the time period between 1 April 1969 and 29 ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Steinhausen HC,Foldager L,Perto G,Munk-Jørgensen P

更新日期：2009-08-01 00:00:00

abstract：:Three groups of married women were studied with each defined by their experience of a different stressful incident (the target event). In the first (the Coronary Group), the husband had suffered a non-fatal myocardial infarction whilst in the second (the Bereaved Group), he had recently died. In the third (the Refuge ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Miller PM,Surtees PG

更新日期：1993-01-01 00:00:00

abstract：:Sustainable observations suggest that suicidal behaviour by itself may have biological correlates, among which those related to the serotonergic synapse hold the key position. Based on the association of suicide and serotonergic dysfunction, it was proposed that genetic mechanisms affecting suicidal behaviour could be...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Stefulj J,Büttner A,Kubat M,Zill P,Balija M,Eisenmenger W,Bondy B,Jernej B

更新日期：2004-08-01 00:00:00

abstract：:A significant comorbidity between attention-deficit/hyperactivity disorder (ADHD) and affective disorders has been consistently reported in adults. Less data regarding the role of personality traits and the influence of ADHD co-occurrence on clinical characteristics and outcome of mood disorders are currently availabl...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Di Nicola M,Sala L,Romo L,Catalano V,Even C,Dubertret C,Martinotti G,Camardese G,Mazza M,Tedeschi D,Callea A,De Risio L,Guelfi JD,Rouillon F,Janiri L,Gorwood P

更新日期：2014-08-01 00:00:00

abstract：AIM:This study examined the extent to which fathers' and infants' interaction behavior were related to children's externalizing behavior problems at age 8 and 11 years. METHODS:In a prospective longitudinal study of children at risk for later psychopathology, 72 fathers and their 3-month-old children were videotaped a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trautmann-Villalba P,Gschwendt M,Schmidt MH,Laucht M

更新日期：2006-09-01 00:00:00

abstract：:Obstetric complications play a role in the pathophysiology of schizophrenia. However, the biological consequences during neurodevelopment until adulthood are unknown. Microarrays have been used for expression profiling in four brain regions of a rat model of neonatal hypoxia as a common factor of obstetric complicatio...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sommer JU,Schmitt A,Heck M,Schaeffer EL,Fendt M,Zink M,Nieselt K,Symons S,Petroianu G,Lex A,Herrera-Marschitz M,Spanagel R,Falkai P,Gebicke-Haerter PJ

更新日期：2010-11-01 00:00:00

abstract：:The description of the heterogeneous phenomenological, pathophysiological, and etiological nature of schizophrenia is under way; however, the relationships between heterogeneity levels are still unclear. We performed a robust cross-sectional study, including a systematic neuropsychological battery, assessment of clini...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Szendi I,Racsmány M,Cimmer C,Csifcsák G,Kovács ZA,Szekeres G,Galsi G,Tóth F,Nagy A,Garab EA,Boda K,Gulyás G,Kiss JG,Dombi J,Pléh C,Janka Z

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Knowledge about psychopathologic presentations of mania in current clinical practice has to be refined in order to improve diagnosis and treatment. METHODS:One thousand ninety manic patients included in the French National Study EPIMAN-II Mille were submitted to a cluster analysis on the basis of multiple v...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Azorin JM,Kaladjian A,Adida M,Hantouche E,Hameg A,Lancrenon S,Akiskal HS

更新日期：2008-12-01 00:00:00

abstract：:Three adult schizophrenic patients without a previous history of epilepsy are reported who, during clozapine treatment, developed paroxysmal EEG patterns and generalized myoclonic jerks without alteration of consciousness. These seizures were phenomenologically identical to those occurring in juvenile myoclonic epilep...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gouzoulis E,Grunze H,von Bardeleben U

更新日期：1991-01-01 00:00:00

abstract：:Negative symptoms were examined in 150 primarily first-admission patients diagnosed with schizophrenia, schizoaffective disorder, psychotic depression, psychotic bipolar disorder, and 'other' psychoses. The analysis focused on patients who were rated on the Scale for the Assessment of Negative Symptoms (SANS) within 4...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Fennig S,Bromet EJ,Galambos N,Putnam K

更新日期：1996-01-01 00:00:00

abstract：:Cognitive impairment is one of the core symptoms of schizophrenia. Multiple domains of cognition are affected in patients with schizophrenia, which has a major effect on the functional outcome. Recent studies indicate that SNPs in the gamma-aminobutyric acid type A receptor beta 2 subunit (GABRB2) gene are associated ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Zhang Q,Zhang X,Song S,Wang S,Wang X,Yu H,Han H,Zhou X,Li G,Wu Y

更新日期：2020-06-01 00:00:00

abstract：:Apathy is a frequent and debilitating condition with few treatment options available in schizophrenia patients. Despite evidence of its multidimensional structure, most of past studies have explored apathy through a categorical approach. The main objective of this study was to identify the cognitive, emotional, motiva...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Raffard S,Bortolon C,Yazbek H,Lançon C,Benoit M,Norton J,Capdevielle D

更新日期：2019-12-01 00:00:00

abstract：:DTNBP1 is one of the most established susceptibility genes for schizophrenia, and hippocampal volume reduction is one of the major neuropathological findings in this severe disorder. Consistent with these findings, the encoded protein dysbindin-1 has been shown to be diminished in glutamatergic hippocampal neurons in ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trost S,Platz B,Usher J,Scherk H,Wobrock T,Ekawardhani S,Meyer J,Reith W,Falkai P,Gruber O

更新日期：2013-02-01 00:00:00

abstract：:The novel coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The escalating number of SARS-CoV-2-infected individuals has conferred the viral spread with the status of global pandemic. However, there are no prophylactic or therapeutic drugs available on the m...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hashimoto K

更新日期：2021-01-05 00:00:00

abstract：:Evidence suggests that the anterior cingulate cortex (ACC) plays a key role in the development of posttraumatic stress disorder (PTSD). Owing to the region's highly variable patterns, three different studies of PTSD have yielded inconsistent volume reductions. Accordingly, in order to measure the correct borders and v...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jatzko A,Vogler C,Demirakca T,Ruf M,Malchow B,Falkai P,Braus DF,Ende G,Schmitt A

更新日期：2013-10-01 00:00:00

abstract：:Increases in seizure threshold (ST) over a course of brief pulse ECT can be predicted by decreases in EEG quality, informing ECT dose adjustment to maintain adequate supra-threshold dosing. ST increases also occur over a course of right unilateral ultrabrief (RUL UB) ECT, but no data exist on the relationship between ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gálvez V,Hadzi-Pavlovic D,Waite S,Loo CK

更新日期：2017-12-01 00:00:00

abstract：:Research on emotional expression in adult schizophrenia patients has indicated an impairment of the patients' facial expressions during social interaction. However, it is unclear whether schizophrenia adolescent-onset patients show comparable disturbances in facial expression. Our aim was to analyze facial emotions in...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Lotzin A,Haack-Dees B,Resch F,Romer G,Ramsauer B

更新日期：2013-09-01 00:00:00

abstract：:Depressive disorders are influenced by a complex interplay between genetic and environmental factors. Multiple studies support a role of serotonergic pathways in the pathophysiology of depressive disorders. As a rate-limiting enzyme of serotonin synthesis in the brain, tryptophan hydroxylase 2 (TPH2) represents a plau...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Van der Auwera S,Janowitz D,Schulz A,Homuth G,Nauck M,Völzke H,Rose M,Meyer zu Schwabedissen H,Freyberger HJ,Grabe HJ

更新日期：2014-11-01 00:00:00

abstract：:Spontaneous Parkinsonism (SP) in schizophrenia-related disorders is poorly characterized. The objective of this study was to examine the concordance and clinical validity of alternative definitions of SP in patients with nonaffective psychotic disorders. Two-hundred drug-naive patients with nonaffective psychotic diso...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Peralta V,Basterra V,Campos MS,de Jalón EG,Moreno-Izco L,Cuesta MJ

更新日期：2012-03-01 00:00:00