Abstract:
:The recent recognition that humans possess active depots of brown adipose tissue has boosted the interest in this tissue as a potential target for the prevention and treatment of obesity and related metabolic disorders. Furthermore, it was also revealed that brown adipose tissue (BAT) in humans may consist of so-called beige or brite adipocytes. So far, cold exposure is recognised as the strongest activator of BAT in humans, but there is much ongoing research focused on finding alternative activators of BAT. The consequences of long-term BAT activation and/or cold exposure on metabolic health are still unknown, and this represents an area of intensive research. This is one of a series of commentaries under the banner '50 years forward', giving personal opinions on future perspectives in diabetes, to celebrate the 50th anniversary of Diabetologia (1965-2015).
journal_name
Diabetologiajournal_title
Diabetologiaauthors
Schrauwen P,van Marken Lichtenbelt WD,Spiegelman BMdoi
10.1007/s00125-015-3611-ysubject
Has Abstractpub_date
2015-08-01 00:00:00pages
1704-7issue
8eissn
0012-186Xissn
1432-0428journal_volume
58pub_type
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