Comparison of biological activity of phenolic fraction from roots of Alhagi maurorum with properties of commercial phenolic extracts and resveratrol.

abstract：:In recent years, there has been exponential growth in the interest in microvesicles, which is reflected by the number of publications. Initially referred to as "platelet dust" by Peter Wolf in 1967, platelet microvesicles (PMV) are now recognized as important mediators of intercellular communication. There are example...

journal_title：Platelets

authors： Edelstein LC

更新日期：2017-05-01 00:00:00

abstract：:Prostaglandins stimulate cyclic AMP synthesis in platelets, leading to inhibition of platelet aggregation. Prostaglandin receptors have been identified but knowledge of their pharmacology is limited by the lack of antagonists. Kinetic measurements of prostaglandinregulated cyclic AMP formation provide useful informati...

journal_title：Platelets

authors： Ashby B

更新日期：1990-01-01 00:00:00

abstract：:Activated platelets serve as a catalyst for thrombin generation and a source of vasoactive and mitogenic factors affecting vascular remodeling. Oral menopausal hormone treatments (MHT) may carry greater thrombotic risk than transdermal products. This study compared effects of oral and transdermal MHT on platelet chara...

journal_title：Platelets

authors： Miller VM,Lahr BD,Bailey KR,Heit JA,Harman SM,Jayachandran M

更新日期：2016-01-01 00:00:00

abstract：:To study the possibility of using thrombin generation tests in platelet-rich and platelet-poor plasma for evaluation of dual antiplatelet therapy efficacy in patients with coronary artery disease (CAD), following percutaneous coronary intervention. Venous blood was analyzed from CAD patients aged 53-75 years who had u...

journal_title：Platelets

authors： Berezovskaya G,Smirnova O,Malev E,Khromov-Borisov N,Klokova E,Karpenko M,Papayan L,Petrishchev N

更新日期：2018-03-01 00:00:00

abstract：:Familial bleeding problems are frequently difficult to diagnose because currently used clinical tests cannot identify intracellular molecular defects of platelets. Using platelet proteomics, a comprehensive analytical tool, we diagnosed a family with severe bleeding problems of unknown origin with Quebec Platelet Diso...

journal_title：Platelets

authors： Maurer-Spurej E,Kahr WH,Carter CJ,Pittendreigh C,Cameron M,Cyr TD

更新日期：2008-08-01 00:00:00

abstract：:Microparticles (MPs) are blebs released from cellular surfaces during activation/apoptosis. They are procoagulant, pro-inflammatory and could contribute to pathogenesis of deep venous thrombosis (DVT). This study compared the number, cellular origin and procoagulant activity of MPs on DVT patients in different clinica...

journal_title：Platelets

authors： Flores-Nascimento MC,Beltrame MP,De Paula EV,Montalvão SL,Pereira FG,Orsi FL,Lorand-Metze I,Annichino-Bizzacchi JM

更新日期：2009-09-01 00:00:00

abstract：:It has recently been demonstrated that both initiators and inhibitors (viz iloprost) of aggregation stimulate the uptake of [(45)Ca(2+)] by human platelets. Since it was postulated that this calcium uptake reflects changes associated with signal transduction, we investigated the role of cAMP-dependent protein kinases ...

journal_title：Platelets

authors： Gill J,Jeremy JY,Mikhailidis DP

更新日期：1993-01-01 00:00:00

abstract：:In this study, we have examined whether the platelet Fc-receptor, FcγRII (CD32), is associated with either of the two major platelet membrane glycoproteins, the GPIb-IX complex and the GPIIb-IIIa complex. Monoclonal and polyclonal anti-GPIb-IX complex antibodies inhibited to only a moderate degree (< 40%) the binding ...

journal_title：Platelets

authors： Berndt MC,Mazurov AV,Vinogradov DV,Burns GF,Chesterman CN

更新日期：1993-01-01 00:00:00

abstract：:Avian influenza A (H7N9) is a serve zoonosis with a high mortality rate. Timely and effective diagnosis and early warning is crucial for the clinical treatment of H7N9 patients. The previous studies indicated that thrombocytopenia was associated with the prognosis of influenza cases, but the related evidence of platel...

journal_title：Platelets

authors： Chen Y,Yang Y,Cheng J,Lu J,Hu W

更新日期：2020-01-01 00:00:00

abstract：:A goal of platelet storage is to maintain the quality of platelets from the point of donation to the point of transfusion - to suspend the aging process. This effort is judged by clinical and laboratory measures with varying degrees of success. Recent work gives encouragement that platelets can be maintained ex vivo b...

journal_title：Platelets

authors： Smethurst PA

更新日期：2016-09-01 00:00:00

abstract：:A pathogen-free and standardized xeno-free supplement of growth media is required for the ex vivo propagation of human cells used as advanced therapeutic medicinal products and for clinical translation in regenerative medicine and cell therapies. Human platelet lysate (HPL) made from therapeutic-grade platelet concent...

journal_title：Platelets

authors： Barro L,Burnouf PA,Chou ML,Nebie O,Wu YW,Chen MS,Radosevic M,Knutson F,Burnouf T

更新日期：2020-11-29 00:00:00

abstract：:Prominence has been given recently to the use of platelet-rich plasma (PRP) in combination with bone graft materials for predictably obtaining periodontal regeneration through bioengineering. The purpose of this report was to present clinical, radiographic and re-entry results of a generalized aggressive periodontitis...

journal_title：Platelets

authors： Yilmaz S,Cakar G,Kuru BE,Yildirim B

更新日期：2007-11-01 00:00:00

abstract：:SUMMARY. Blood platelets exposed to hypotonic medium are known to undergo a regulatory volume decrease (RVD), mediated by increased conductive permeability of K(+) and Cl(-). It is presently shown that RVD in platelets is controlled by a lipoxygenase product, apparently by a selective regulation of K(+) permeability. ...

journal_title：Platelets

authors： Margalit A,Livne AA

更新日期：1991-01-01 00:00:00

abstract：:Bioactive substances found in numerous foods can be successfully and safely used to modify various cellular functions and affect the oxidative stress. Aronia melanocarpa fruits (Rosaceae) are one of the richest plant sources of phenolic substances shown to have anti-inflammatory, antitumor, antioxidative and antiplate...

journal_title：Platelets

authors： Olas B,Kedzierska M,Wachowicz B,Stochmal A,Oleszek W

更新日期：2010-01-01 00:00:00

abstract：:To test the role of platelet activation in the prognosis of nephrotic syndrome (NS), we evaluated the mean platelet volume (MPV) in patients with NS undergoing treatment. In this prospective, multicenter clinical study 156 patients with primary NS under treatment were assigned and followed for one year. Patients were ...

journal_title：Platelets

authors： Kocyigit I,Yilmaz MI,Simşek Y,Unal A,Sipahioglu MH,Eroglu E,Dede F,Tokgoz B,Oymak O,Utas C

更新日期：2013-01-01 00:00:00

abstract：:Catastrophic antiphospholipid syndrome (CAPS) involves sudden multiorgan dysfunction from thrombosis due to antibodies that cause platelet activation and endothelial dysfunction. Treatment variably combines anticoagulation, corticosteroid use, therapeutic plasma exchange (TPE), and high-dose intravenous immunoglobulin...

journal_title：Platelets

authors： James TE,Martin LJ,Warkentin TE,Crowther MA

更新日期：2020-08-07 00:00:00

abstract：:The aim of the study was to evaluate how platelet aggregation relates to left ventricular hypertrophy, presence of transient myocardial ischemia and coronary atherosclerosis in essential hypertensive patients. For that purpose platelet aggregation, symptom-limited treadmill-test, echocardiography and coronary angiogra...

journal_title：Platelets

authors： Gabbasov Z,Parfyonova Y,Popov E,Gavrilov I,Anuchin V,Dubov P,Djakonova Y

更新日期：1998-01-01 00:00:00

abstract：:The tetraspanins are a superfamily of membrane glycoproteins which facilitate the interaction of membrane and intracellular signalling molecules (e.g., integrins, pro-growth factors and their receptors, protein kinase-C) in the formation of membrane signalling microdomains (sometimes referred to as the tetraspanin web...

journal_title：Platelets

authors： Moseley GW

更新日期：2005-02-01 00:00:00

abstract：:We investigated the relationship between the expression of IFN-gamma, IL-4, Foxp3 and perforin gene and the methylation status of their promoters in immune thrombocytopenic purpura (ITP) patients. Gene expression and DNA methylation were determined by quantitative PCR and bisulfite genomic sequencing, respectively. Th...

journal_title：Platelets

authors： Zhao H,Du W,Wang D,Gu D,Xue F,Ge J,Sui T,Yang R

更新日期：2010-01-01 00:00:00

abstract：:Previous studies have reported increased platelet activation and aggregation in patients with obstructive sleep apnea (OSA). Continuous positive airway pressure (CPAP) treatment has been shown to decrease platelet activation. We aimed to study the effects of nasal CPAP therapy has on MPV values in patients with severe...

journal_title：Platelets

authors： Varol E,Ozturk O,Yucel H,Gonca T,Has M,Dogan A,Akkaya A

更新日期：2011-01-01 00:00:00

abstract：:Studies have reported the polymorphism of human platelet antigen (HPA)-17w, -18w, -19w, -20w, and -21w. However, the distribution of these five antigens in Chinese Cantonese is still unknown. In this study, we designed new sequence-specific primers for HPA-19w to -21w and used published primers for HPA-17w and -18w to...

journal_title：Platelets

authors： Zhou H,Ding H,Chen Y,Li X,Ye X,Nie Y

更新日期：2015-01-01 00:00:00

abstract：:The risk and benefit of GP-IIb/IIIa Inhibition (GPI) in combination with recent antiplatelet regimens in acute coronary syndromes (ACS) remain unassessed. The advent of fast-acting highly active oral P2Y12 inhibitors questions the additional value and risk of their association with GPI. We studied the effect of GPI in...

journal_title：Platelets

authors： Roule V,Agueznai M,Sabatier R,Blanchart K,Lemaître A,Ardouin P,Collet JP,Milliez P,Montalescot G,Beygui F

更新日期：2017-03-01 00:00:00

abstract：:Information regarding the profile of reticulated platelets (RP) in ischemic cerebrovascular disease (CVD) patients is limited. Data from two prospective, observational, case-control studies were combined to compare the %RP using whole blood flow cytometry in patients ≤ 4 weeks of TIA/stroke onset (baseline, N = 210), ...

journal_title：Platelets

authors： Lim ST,Tobin WO,Murphy S,Kinsella JA,Smith DR,Lim SY,Murphy SM,Coughlan T,Collins DR,O'Neill D,Egan B,Tierney S,McCabe D

更新日期：2020-12-21 00:00:00

abstract：:Plasma lipid composition, platelet aggregation, cholesterol (Ch)/glycoprotein IIb-IIIa (GP) and phospholipid (Ph)/GP molar ratios, fatty acid composition and structural order (1, 6-diphenyl-1, 3, 5-hexatriene (DPH) fluorescence anisotropy at 35 degrees C (r(DPH,35)) of human platelet plasma membranes (HPPM) were measu...

journal_title：Platelets

authors： García-Guerra R,Mateo CR,García-Muñoz MS,Zapata MA,Plaza I,González-Rodríguez J

更新日期：1998-01-01 00:00:00

abstract：:Human melanoma cell Line, HMV-I, has been shown to induce platelet aggregation without thrombin generation. The platelet-aggregating activity of HMV-I cells increased with increasing culture periods of the cells. However, data indicate that the platelet-aggregating activity of HMV-I cells is dependent upon the cell de...

journal_title：Platelets

authors： Katagiri Y,Hayashi Y,Baba I,Yamazaki H,Tanoue K

更新日期：1995-01-01 00:00:00

abstract：:Lipid-rafts are defined as membrane microdomains enriched in cholesterol and glycosphingolipids within platelet plasma membrane. Lipid raft-mediated clot retraction requires factor XIII and other interacting proteins. The aim of this study was to investigate the proteins that interact with factor XIII in raft and non-...

journal_title：Platelets

authors： Rabani V,Montange D,Davani S

更新日期：2016-09-01 00:00:00

abstract：:Impaired glucose tolerance (IGT), a prediabetic state, is associated with an increased risk of cardiovascular disease. Mean platelet volume (MPV), a determinant of platelet activation, is a newly emerging risk factor for atherothrombosis. This study was designed to answer the following questions: (i) Do MPV levels cha...

journal_title：Platelets

authors： Coban E,Kucuktag S,Basyigit S

更新日期：2007-12-01 00:00:00

abstract：:Whether the simultaneous administration of ciprofloxacin or tazobactam/piperacillin increases the risk of thrombocytosis is unknown. Broncho-pulmonary infection in a 50-year-old male with acute, hypertensive, intracerebral bleeding, necessitated therapy with cefpirome (2 g/day, 6 days), ciprofloxacin (800 mg/d, 11 day...

journal_title：Platelets

authors： Finsterer J,Kotzailias N

更新日期：2003-08-01 00:00:00

abstract：:Mean platelet volume (MPV), a determinant of platelet function, is a newly emerging risk factor for atherothrombosis. Impaired fasting glucose (IFG) is probably a frequent glycemic disorder in the general population and is considered as a prediabetic state. The present study was designed to evaluate MPV in subjects wi...

journal_title：Platelets

authors： Coban E,Bostan F,Ozdogan M

更新日期：2006-02-01 00:00:00

abstract：:Postoperative atrial fibrillation (AF) is a common complication of coronary artery bypass grafting (CABG). The mean platelet volume (MPV) is an important marker of platelet activity and is associated with cardiovascular risk factors. We investigated whether the MPV is associated with the development of AF after CABG. ...

journal_title：Platelets

authors： Erdem K,Ayhan S,Ozturk S,Bugra O,Bozoglan O,Dursin H,Yazici M,Daglar B

更新日期：2014-01-01 00:00:00