Simultaneous genotyping of HPA-17w to -21w by PCR-SSP in Chinese Cantonese.

abstract：:Platelet aggregation in response to ADP, adrenaline, collagen, arachidonic acid and ristocetin was measured in a large population of healthy Saudi males (n = 393) and females (n = 221) whose age ranged from 11-60 years. The number of observations ranged from 130 for one of the doses of ristocetin (1.0 g/l) to 554 for ...

journal_title：Platelets

authors： Gader AM,Bahakim HM,Malaika SS

更新日期：1990-01-01 00:00:00

abstract：:A pathogen-free and standardized xeno-free supplement of growth media is required for the ex vivo propagation of human cells used as advanced therapeutic medicinal products and for clinical translation in regenerative medicine and cell therapies. Human platelet lysate (HPL) made from therapeutic-grade platelet concent...

journal_title：Platelets

authors： Barro L,Burnouf PA,Chou ML,Nebie O,Wu YW,Chen MS,Radosevic M,Knutson F,Burnouf T

更新日期：2020-11-29 00:00:00

abstract：:A controversial discussion as to whether human platelets are capable of regulated protein synthesis has been ongoing for over half a century. A previous study has suggested that human platelets synthesize large amounts of interleukin 1beta (IL-1beta) in response to external cues and in a physiologically significant ma...

journal_title：Platelets

authors： Pillitteri D,Bassus S,Boller K,Mahnel R,Scholz T,Westrup D,Wegert W,Kirchmaier CM

更新日期：2007-03-01 00:00:00

abstract：:The Total Thrombus-formation Analyser System (T-TAS) is a whole blood flow chamber system for the measurement of in vitro thrombus formation under variable shear stress conditions. Our current study sought to evaluate the potential utility of the T-TAS for the measurement of thrombus formation within human and mouse w...

journal_title：Platelets

authors： Al Ghaithi R,Mori J,Nagy Z,Maclachlan A,Hardy L,Philippou H,Hethershaw E,Morgan NV,Senis YA,Harrison P

更新日期：2019-01-01 00:00:00

abstract：:The aim of the study was to evaluate how platelet aggregation relates to left ventricular hypertrophy, presence of transient myocardial ischemia and coronary atherosclerosis in essential hypertensive patients. For that purpose platelet aggregation, symptom-limited treadmill-test, echocardiography and coronary angiogra...

journal_title：Platelets

authors： Gabbasov Z,Parfyonova Y,Popov E,Gavrilov I,Anuchin V,Dubov P,Djakonova Y

更新日期：1998-01-01 00:00:00

abstract：:Platelet aggregation is usually measured by a spectroscopic method using an aggregometer. However, when the process of platelet aggregation is followed by the changes in light transmission of platelet-rich plasma (PRP), factors such as platelet deformation or changes in plasma permeability must be taken into considera...

journal_title：Platelets

authors： Suehiro A,Higashi T,Kakishita E

更新日期：1992-01-01 00:00:00

abstract：:Recombinant human erythropoietin is a successful treatment for the anaemia of renal failure. Its use has however been associated with thromboembolic complications. Changes in platelet number and behaviour in vitro were studied in: (1) 23 haemodialysis patients, and 10 continuous ambulatory peritoneal dialysis patients...

journal_title：Platelets

authors： Taylor JE,Henderson IS,Stewart WK,Belch JJ

更新日期：1992-01-01 00:00:00

abstract：:Platelets, besides their specialised role in haemostasis and atherothrombosis, actively modulate innate and adaptive immune responses with crucial roles in immune surveillance, inflammation and host defence during infection. An important prerequisite for platelet-mediated changes of immune functions involves direct en...

journal_title：Platelets

authors： Finsterbusch M,Schrottmaier WC,Kral-Pointner JB,Salzmann M,Assinger A

更新日期：2018-11-01 00:00:00

abstract：:Aspirin and Clopidogrel are used in prophylaxis of patients undergoing percutaneous coronary intervention and long-term prevention of cardiovascular and cerebrovascular events. Clopidogrel resistance has been attributed to P2Y1 and P2Y12 adenosine diphosphate (ADP) receptor polymorphisms. This study enrolled 100 patie...

journal_title：Platelets

authors： Kar R,Meena A,Yadav BK,Yadav R,Kar SS,Saxena R

更新日期：2013-01-01 00:00:00

abstract：:Platelets play a key role in thrombotic vascular occlusion at the side of an atherosclerotic plaque. Malondialdehyde (MDA) derivatives are components of oxidized LDL. Recent studies suggest enhanced adhesion of platelets on oxidized LDL, but evidence of MDA-modified LDL contribution to enhanced platelet adhesion is mi...

journal_title：Platelets

authors： Suttnar J,Otáhalová E,Cermák J,Dyr JE

更新日期：2006-03-01 00:00:00

abstract：:Bernard-Soulier Syndrome (BSS) is an inherited recessive bleeding disorder. In some instances, diagnosis might be restricted to routine blood exams, including bleeding time, prothrombin time (PT), and partial thromboplastin time (APTT). Exams such as platelet aggregation, and testing for expression of ristocetin cofac...

journal_title：Platelets

authors： Beltrame MP,Malvezzi M,Zanis J,Pasquini R

更新日期：2009-06-01 00:00:00

abstract：:Bioactive substances found in numerous foods can be successfully and safely used to modify various cellular functions and affect the oxidative stress. Aronia melanocarpa fruits (Rosaceae) are one of the richest plant sources of phenolic substances shown to have anti-inflammatory, antitumor, antioxidative and antiplate...

journal_title：Platelets

authors： Olas B,Kedzierska M,Wachowicz B,Stochmal A,Oleszek W

更新日期：2010-01-01 00:00:00

abstract：:The isolation of mitochondria is gaining importance in experimental and clinical laboratory settings. The mitochondrion is known as the powerhouse of the cell as it produces the energy to power most cellular functions but is also involved in many cellular processes. Of interest, mitochondria and mitochondrial componen...

journal_title：Platelets

authors： Léger JL,Jougleux JL,Savadogo F,Pichaud N,Boudreau LH

更新日期：2020-01-01 00:00:00

abstract：:Thrombocytopenia is one of the most frequent hematologic abnormalities in the neonatal period, affecting about 18-35% of all patients admitted to the Neonatal Intensive Care Unit (NICU), with sepsis being among the most common causes of severe neonatal thrombocytopenia. It is unclear whether decreased platelet product...

journal_title：Platelets

authors： Eissa DS,El-Farrash RA

更新日期：2013-01-01 00:00:00

abstract：:The tetraspanins are a superfamily of membrane glycoproteins which facilitate the interaction of membrane and intracellular signalling molecules (e.g., integrins, pro-growth factors and their receptors, protein kinase-C) in the formation of membrane signalling microdomains (sometimes referred to as the tetraspanin web...

journal_title：Platelets

authors： Moseley GW

更新日期：2005-02-01 00:00:00

abstract：:The aim of this survey was to describe drug-induced immune thrombocytopenia (ITP) reported in the French PharmacoVigilance database (FPVD) and to discuss the drugs involved. The request to the FPVD used the seven most accurate diagnosis codes to identify ITP. The study was restricted to cases reported from 2007 to 201...

journal_title：Platelets

authors： Moulis G,Sommet A,Sailler L,Lapeyre-Mestre M,Montastruc JL,French Association Of Regional Pharmacovigilance Centers.

更新日期：2012-01-01 00:00:00

abstract：:Dopamine (DA), a catecholamine neurotransmitter, is known to for its diverse roles on hematopoiesis, yet its function in thrombopoiesis remains poorly understood. This study shows that DA stimulation can directly induce platelet production from megakaryocytes (MKs) in the final stages of thrombopoiesis via a reactive ...

journal_title：Platelets

authors： Chen S,Hu M,Shen M,Xu Y,Wang C,Wang X,Li F,Zeng D,Chen F,Zhao G,Chen M,Wang F,Cheng T,Su Y,Zhao J,Wang S,Wang J

更新日期：2018-11-01 00:00:00

abstract：:Flow cytometric analysis of human platelets from healthy volunteers by high-resolution immunophenotyping accomplished with enzymatic amplification staining revealed the expression of CD34. Assessment of the platelets with five different monoclonal antibodies to the three different classes of CD34 epitopes suggested th...

journal_title：Platelets

authors： Lewandowska K,Kaplan D,Husel W

更新日期：2003-03-01 00:00:00

abstract：:We prospectively investigated the prevalence of Helicobacter pylori (H. pylori) infection in a cohort of 54 adult Serbian patients with chronic idiopathic thrombocytopenic purpura (ITP), and examined the effects of its eradication on their platelet counts. H. pylori infection was diagnosed in 39/54 (72.2%) patients, u...

journal_title：Platelets

authors： Suvajdzić N,Stanković B,Artiko V,Cvejić T,Bulat V,Bakrac M,Colović M,Obradović V,Atkinson HD

更新日期：2006-06-01 00:00:00

abstract：:Phenolic compounds have different biological properties, including antioxidative activities, but they may also be prooxidants. The effect of phenolic fraction from roots of Alhagi maurorum on oxidative protein/lipid damages (determined by such parameters as levels of protein thiol groups and the concentration of thiob...

journal_title：Platelets

authors： Olas B,Hamed AI,Oleszek W,Stochmal A

更新日期：2015-01-01 00:00:00

abstract：:Functional and genetic assays for measuring platelet microvesicles (PMVs) are presented and discussed. Functional assays concern two groups of methods: a) homogeneous assays using the cofactor activity of phospholipids (PPLs) contained in PMVs and present in assayed plasmas, and a coagulation or a thrombin generation ...

journal_title：Platelets

authors： Laroche M,Dunois C,Vissac AM,Amiral J

更新日期：2017-05-01 00:00:00

abstract：:In aspirin-treated platelets labelled by preincubation with [(3)H]-choline, enhanced release of both [(3)H]-choline and [(3)H]-choline phosphate resulted from stimulation by collagen or thrombin. No such release accompanied stimulation by ADP, platelet-activating factor or adrenaline. Release of [(3)H]-choline phospha...

journal_title：Platelets

authors： Petty AC,Scrutton MC

更新日期：1993-01-01 00:00:00

abstract：:Peroxynitrite is a potent nitrating and oxidizing agent that exerts differential effects on platelets. In the present study we investigated the influence of peroxynitrite on vasodilator-stimulated phosphoprotein (VASP), a protein that plays a key role in inhibition of platelet adhesion and spreading. In platelets, VAS...

journal_title：Platelets

authors： Aburima A,Riba R,Naseem KM

更新日期：2010-01-01 00:00:00

abstract：:In the presence of large bone defects, delayed bone union, or nonunion and fractures, bone reconstruction may be necessary. Different strategies have been employed to enhance bone healing among which the use of autologous platelet concentrates (APCs). Due to the high content of platelets and platelet-derived bioactive...

journal_title：Platelets

authors： Marcazzan S,Taschieri S,Weinstein RL,Del Fabbro M

更新日期：2018-06-01 00:00:00

abstract：:We report a case of total hyperpigmentation of the skin, severe itching, muscle weakness and thrombocytosis. Laboratory investigation showed white blood cell (WBC) 8.2 x 10(6)/L, Hb 125 g/L, platelets 1221 x 10(6)/L and urinary lead after DMSA mobilization test 2684 mcg/g creatinine (normal <5). Chelation therapy with...

journal_title：Platelets

authors： Al Momen A

更新日期：2010-01-01 00:00:00

abstract：:Metabolic syndrome (MS) is becoming globally prevalent and it is clinically important because of its association with type 2 diabetes and cardiovascular disease, and some cancers. Recently, platelet count has been linked to insulin resistance and MS in addition to being a marker of hemostasis. Also, mean platelet volu...

journal_title：Platelets

authors： Park BJ,Shim JY,Lee HR,Jung DH,Lee JH,Lee YJ

更新日期：2012-01-01 00:00:00

abstract：:Previous investigations from our laboratory identified the ultrastructural pathology and cytochemistry of macrothrombocytes (MTC) from patients with the X-linked, G208S varient of the GATA-1 mutation.A subsequent biochemical study of the MTC cytoskeletal proteins using polyacrylamide gel electrophoresis and western bl...

journal_title：Platelets

authors： White JG,Burris SM,Crowe BR

更新日期：2009-05-01 00:00:00

abstract：:Fibrin glue is a promising alternative for low-output enterocutaneous fistula closure. Bacterial flora colonizing inside the fistula tract, however, may limit the glue application. Single-donor-derived, platelet-rich materials were hypothesized in this study to have antimicrobial activity against Gram-negative microor...

journal_title：Platelets

authors： Wu X,Ren J,Yuan Y,Luan J,Yao G,Li J

更新日期：2013-01-01 00:00:00

abstract：:Platelets in flowing blood at high-shear stress are recruited to exposed subendothelial collagen of injured vessels by GPIb-von Willebrand factor (vWf) and integrin alpha(2)beta(1) (alpha(2)beta(1))-collagen interactions. Platelet adhesion to type I collagen depends mainly on the alpha(2)beta(1)-collagen interaction a...

journal_title：Platelets

authors： Jung SM,Sonoda M,Tsuji K,Jimi A,Nomura S,Kanaji T,Moroi M

更新日期：2010-01-01 00:00:00

abstract：:Platelet storage is associated with deleterious changes leading to the loss of platelet reactivity and response. During storage, platelets experience increased expression and shedding of P-selectin and CD40L as specific markers of platelet activation, whereas GPIbα decreases due to ectodomain shedding. As an important...

journal_title：Platelets

authors： Hosseini E,Ghasemzadeh M,Nassaji F,Jamaat ZP

更新日期：2017-07-01 00:00:00