Anomalous fracture in two-dimensional rhenium disulfide.

abstract：:The single-stranded RNA (ssRNA) bacteriophages are among the simplest known viruses with small genomes and exceptionally high mutation rates. The number of ssRNA phage isolates has remained very low, but recent metagenomic studies have uncovered an immense variety of distinct uncultured ssRNA phages. The coat proteins...

journal_title：Science advances

authors： Rūmnieks J,Liekniņa I,Kalniņš G,Šišovs M,Akopjana I,Bogans J,Tārs K

更新日期：2020-09-02 00:00:00

abstract：:The retinoic acid-inducible gene I (RIG-I) innate immune receptor is an important immunotherapeutic target, but we lack approaches for monitoring the physical basis for its activation in vitro. This gap in our understanding has led to confusion about mechanisms of RIG-I activation and difficulty discovering agonists a...

journal_title：Science advances

authors： Dickey TH,Song B,Pyle AM

更新日期：2019-10-02 00:00:00

abstract：:A novel, thin-film platform that preserves live viruses, bacteria, antibodies, and enzymes without refrigeration for extended periods of time is described. Studies with recombinant adenovirus in an optimized formulation that supports recovery of live virus through 16 freeze-thaw cycles revealed that production of an a...

journal_title：Science advances

authors： Bajrovic I,Schafer SC,Romanovicz DK,Croyle MA

更新日期：2020-03-04 00:00:00

abstract：:The spin-polarized surface states of topological insulators (TIs) are attractive for applications in spintronics and quantum computing. A central challenge with these materials is to reliably tune the chemical potential of their electrons with respect to the Dirac point and the bulk bands. We demonstrate persistent, b...

journal_title：Science advances

authors： Yeats AL,Pan Y,Richardella A,Mintun PJ,Samarth N,Awschalom DD

更新日期：2015-10-09 00:00:00

abstract：:Massive declines in population abundances of marine animals have been documented over century-long time scales. However, analogous loss of spatial extent of habitat-forming organisms is less well known because georeferenced data are rare over long time scales, particularly in subtidal, tropical marine regions. We use ...

journal_title：Science advances

authors： McClenachan L,O'Connor G,Neal BP,Pandolfi JM,Jackson JBC

更新日期：2017-09-06 00:00:00

abstract：:Earthquakes in the continental crust commonly occur in the upper 15 to 20 km. Recent studies demonstrate that earthquakes also occur in the lower crust of collision zones and play a key role in metamorphic processes that modify its physical properties. However, details of the failure process and sequence of events tha...

journal_title：Science advances

authors： Petley-Ragan A,Ben-Zion Y,Austrheim H,Ildefonse B,Renard F,Jamtveit B

更新日期：2019-07-31 00:00:00

abstract：:Large earthquakes occur in rocks undergoing high-pressure/low-temperature metamorphism during subduction. Rhythmic major-element zoning in garnet is a common product of such metamorphism, and one that must record a fundamental subduction process. We argue that rhythmic major-element zoning in subduction zone garnets f...

journal_title：Science advances

authors： Viete DR,Hacker BR,Allen MB,Seward GGE,Tobin MJ,Kelley CS,Cinque G,Duckworth AR

更新日期：2018-03-21 00:00:00

abstract：:Wearable sweat analysis devices for monitoring of multiple health-related biomarkers with high sensitivity are highly desired for noninvasive and real-time monitoring of human health. Here, we report a flexible sweat analysis patch based on a silk fabric-derived carbon textile for simultaneous detection of six health-...

journal_title：Science advances

authors： He W,Wang C,Wang H,Jian M,Lu W,Liang X,Zhang X,Yang F,Zhang Y

更新日期：2019-11-08 00:00:00

abstract：:Multicellular organisms are composed of tissues that have distinct functions requiring specialized proteomes. To define the proteome of a live animal with tissue and subcellular resolution, we adapted a localized proteomics technology for use in the multicellular model organism Caenorhabditis elegans. This approach co...

journal_title：Science advances

authors： Reinke AW,Mak R,Troemel ER,Bennett EJ

更新日期：2017-05-10 00:00:00

abstract：:The notorious ~60° bend separating the Hawaiian and Emperor chains marked a prominent change in the motion of the Pacific plate at ~47 Ma (million years ago), but the origin of that change remains an outstanding controversy that bears on the nature of major plate reorganizations. Lesser known but equally significant i...

journal_title：Science advances

authors： Domeier M,Shephard GE,Jakob J,Gaina C,Doubrovine PV,Torsvik TH

更新日期：2017-11-08 00:00:00

abstract：:This study introduces new methods of screening for and tuning chiral space and in so doing identifies a promising set of chiral ligands for asymmetric synthesis. The carbafructopyranosyl-1,2-diamine(s) and salens constructed therefrom are particularly compelling. It is shown that by removing the native anomeric effect...

journal_title：Science advances

authors： Karukurichi KR,Fei X,Swyka RA,Broussy S,Shen W,Dey S,Roy SK,Berkowitz DB

更新日期：2015-07-01 00:00:00

abstract：:Biodiversity loss is a social and ecological emergency, and calls have been made for the global expansion of protected areas (PAs) to tackle this crisis. It is unclear, however, where best to locate new PAs to protect biodiversity cost-effectively. To answer this question, we conducted a spatial meta-analysis by overl...

journal_title：Science advances

authors： Yang R,Cao Y,Hou S,Peng Q,Wang X,Wang F,Tseng TH,Yu L,Carver S,Convery I,Zhao Z,Shen X,Li S,Zheng Y,Liu H,Gong P,Ma K

更新日期：2020-09-09 00:00:00

abstract：:Leukemia is a complex heterogeneous disease often driven by the expression of oncogenic fusion proteins with different molecular and biochemical properties. Whereas several fusion proteins induce leukemogenesis by activating Hox gene expression (Hox-activating fusions), others impinge on different pathways that do not...

journal_title：Science advances

authors： Rossi A,Ferrari KJ,Piunti A,Jammula S,Chiacchiera F,Mazzarella L,Scelfo A,Pelicci PG,Pasini D

更新日期：2016-10-07 00:00:00

abstract：:Nanomaterials often surprise us with unexpected phenomena. Here, we report a discovery of the anti-twinning deformation, previously thought impossible, in nanoscale body-centered cubic (BCC) tungsten crystals. By conducting in situ transmission electron microscopy nanomechanical testing, we observed the nucleation and...

journal_title：Science advances

authors： Wang J,Zeng Z,Wen M,Wang Q,Chen D,Zhang Y,Wang P,Wang H,Zhang Z,Mao SX,Zhu T

更新日期：2020-06-03 00:00:00

abstract：:Coordinatively unsaturated (CUS) iron sites are highly active in catalytic oxidation reactions; however, maintaining the CUS structure of iron during heterogeneous catalytic reactions is a great challenge. Here, we report a strategy to stabilize single-atom CUS iron sites by embedding highly dispersed FeN4 centers in ...

journal_title：Science advances

authors： Deng D,Chen X,Yu L,Wu X,Liu Q,Liu Y,Yang H,Tian H,Hu Y,Du P,Si R,Wang J,Cui X,Li H,Xiao J,Xu T,Deng J,Yang F,Duchesne PN,Zhang P,Zhou J,Sun L,Li J,Pan X,Bao X

更新日期：2015-12-04 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is life-threatening because of limited therapies and lack of effective therapeutic targets. Here, we found that moesin (MSN) was significantly overexpressed in TNBC compared with other subtypes of breast cancer and was positively correlated with poor overall survival. However, litt...

journal_title：Science advances

authors： Qin Y,Chen W,Jiang G,Zhou L,Yang X,Li H,He X,Wang HL,Zhou YB,Huang S,Liu S

更新日期：2020-02-19 00:00:00

abstract：:Toxins efficiently deliver cargo to cells by binding to cell surface ligands, initiating endocytosis, and escaping the endolysosomal pathway into the cytoplasm. We took advantage of this delivery pathway by conjugating an attenuated diphtheria toxin to siRNA, thereby achieving gene downregulation in patient-derived gl...

journal_title：Science advances

authors： Arnold AE,Smith LJ,Beilhartz GL,Bahlmann LC,Jameson E,Melnyk RA,Shoichet MS

更新日期：2020-05-01 00:00:00

abstract：:Topological superconductors are exotic phases of matter featuring robust surface states that could be leveraged for topological quantum computation. A useful guiding principle for the search of topological superconductors is to relate the topological invariants with the behavior of the pairing order parameter on the n...

journal_title：Science advances

authors： Ono S,Po HC,Watanabe H

更新日期：2020-05-01 00:00:00

abstract：:Confined to a two-dimensional plane, electrons in a strong magnetic field travel along the edge in one-dimensional quantum Hall channels that are protected against backscattering. These channels can be used as solid-state analogs of monochromatic beams of light, providing a unique platform for studying electron interf...

journal_title：Science advances

authors： Wei DS,van der Sar T,Sanchez-Yamagishi JD,Watanabe K,Taniguchi T,Jarillo-Herrero P,Halperin BI,Yacoby A

更新日期：2017-08-18 00:00:00

abstract：:The biophysical and biochemical properties of live tissues are important in the context of development and disease. Methods for evaluating these properties typically involve destroying the tissue or require specialized technology and complicated analyses. Here, we present a novel, noninvasive methodology for determini...

journal_title：Science advances

authors： Gross-Thebing S,Truszkowski L,Tenbrinck D,Sánchez-Iranzo H,Camelo C,Westerich KJ,Singh A,Maier P,Prengel J,Lange P,Hüwel J,Gaede F,Sasse R,Vos BE,Betz T,Matis M,Prevedel R,Luschnig S,Diz-Muñoz A,Burger M,Raz E

更新日期：2020-12-04 00:00:00

abstract：:Super-resolution nanoscopy based on wide-field microscopic imaging provided high efficiency but limited resolution. Here, we demonstrate a general strategy to push its resolution down to ~50 nm, which is close to the range of single molecular localization microscopy, without sacrificing the wide-field imaging advantag...

journal_title：Science advances

authors： Liu C,Liu W,Wang S,Li H,Lv Z,Zhang F,Zhang D,Teng J,Zheng T,Li D,Zhang M,Xu P,Gong Q

更新日期：2020-04-17 00:00:00

abstract：:The first example of a homogeneous silver(I)-catalyzed aerobic oxidation of aldehydes in water is reported. More than 50 examples of different aliphatic and aromatic aldehydes, including natural products, were tested, and all of them successfully underwent aerobic oxidation to give the corresponding carboxylic acids i...

journal_title：Science advances

authors： Liu M,Wang H,Zeng H,Li CJ

更新日期：2015-03-27 00:00:00

abstract：:Transplanting beneficial bacteria to the gut microbiome can positively modulate the bacterial composition and remains of great interest in prevention and treatment. However, environmental assaults and rapid transit times in the gastrointestinal (GI) tract result in low oral bioavailability and limited intestinal colon...

journal_title：Science advances

authors： Wang X,Cao Z,Zhang M,Meng L,Ming Z,Liu J

更新日期：2020-06-24 00:00:00

abstract：:Pressure is a key parameter in the physics and chemistry of planet formation and evolution. Previous studies have erroneously assumed that internal pressures monotonically increase with the mass of a body. Using smoothed particle hydrodynamics and potential field method calculations, we demonstrate that the hot, rapid...

journal_title：Science advances

authors： Lock SJ,Stewart ST

更新日期：2019-09-04 00:00:00

abstract：:The attraction between electrons and holes in semiconductors forms excitons, which largely determine the optical properties of the hosting material, and hence the device performance, especially for low-dimensional systems. Mono- and few-layer black phosphorus (BP) are emerging two-dimensional (2D) semiconductors. Desp...

journal_title：Science advances

authors： Zhang G,Chaves A,Huang S,Wang F,Xing Q,Low T,Yan H

更新日期：2018-03-16 00:00:00

abstract：:Maximizing the sustainable supercurrent density, J C, is crucial to high-current applications of superconductivity. To achieve this, preventing dissipative motion of quantized vortices is key. Irradiation of superconductors with high-energy heavy ions can be used to create nanoscale defects that act as deep pinning po...

journal_title：Science advances

authors： Massee F,Sprau PO,Wang YL,Davis JC,Ghigo G,Gu GD,Kwok WK

更新日期：2015-05-20 00:00:00

abstract：:Predator-prey interactions revealed by vertebrate trace fossils are extremely rare. We present footprint evidence from White Sands National Monument in New Mexico for the association of sloth and human trackways. Geologically, the sloth and human trackways were made contemporaneously, and the sloth trackways show evid...

journal_title：Science advances

authors： Bustos D,Jakeway J,Urban TM,Holliday VT,Fenerty B,Raichlen DA,Budka M,Reynolds SC,Allen BD,Love DW,Santucci VL,Odess D,Willey P,McDonald HG,Bennett MR

更新日期：2018-04-25 00:00:00

abstract：:Quantitative three-dimensional (3D) computed tomography (CT) imaging of living single cells enables orientation-independent morphometric analysis of the intricacies of cellular physiology. Since its invention, x-ray CT has become indispensable in the clinic for diagnostic and prognostic purposes due to its quantitativ...

journal_title：Science advances

authors： Kelbauskas L,Shetty R,Cao B,Wang KC,Smith D,Wang H,Chao SH,Gangaraju S,Ashcroft B,Kritzer M,Glenn H,Johnson RH,Meldrum DR

更新日期：2017-12-06 00:00:00

abstract：:The Mott metal-insulator transition, a paradigm of strong electron-electron correlations, has been considered as a source of intriguing phenomena. Despite its importance for a wide range of materials, fundamental aspects of the transition, such as its universal properties, are still under debate. We report detailed me...

journal_title：Science advances

authors： Gati E,Garst M,Manna RS,Tutsch U,Wolf B,Bartosch L,Schubert H,Sasaki T,Schlueter JA,Lang M

更新日期：2016-12-07 00:00:00

abstract：:Dust condensation and coagulation in the early solar system are the first steps toward forming the terrestrial planets, but the time scales of these processes remain poorly constrained. Through isotopic analysis of small Ca-Al-rich inclusions (CAIs) (30 to 100 μm in size) found in one of the most pristine chondrites, ...

journal_title：Science advances

authors： Liu MC,Han J,Brearley AJ,Hertwig AT

更新日期：2019-09-11 00:00:00