Rapid development of pancreatitis following reuse of 6-mercaptopurine.

abstract：BACKGROUND:Pancreatic cancer (PC) is one of the leading causes of cancer death in Western countries. An increased risk for PC is known in a number of hereditary tumor syndromes. In selected individuals at high risk of developing PC, surveillance of the pancreas might be able to detect premalignant lesions and early inv...

journal_title：Journal of clinical gastroenterology

authors： Kluijt I,Cats A,Fockens P,Nio Y,Gouma DJ,Bruno MJ

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The efficacy of 6-mercaptopurine (6-MP) in the treatment and long-term maintenance of remission of inflammatory bowel disease and prevention of recurrence after resection in Crohn's disease have been established. Concern about 6-MP toxicity remains, especially the development of neoplasm. The aim of...

journal_title：Journal of clinical gastroenterology

authors： Warman JI,Korelitz BI,Fleisher MR,Janardhanam R

更新日期：2003-09-01 00:00:00

abstract：:Helicobacter pylori antibody testing is accurate for diagnosing untreated patients. Rapid serum testing is as accurate as formal enzyme-linked immunosorbent assay (ELISA) testing. As whole blood fingerstick tests may become the diagnostic method of choice if they are of similar accuracy, 51 patients were studied who h...

journal_title：Journal of clinical gastroenterology

authors： Harrison JR,Bevan J,Furth EE,Metz DC

更新日期：1998-07-01 00:00:00

abstract：:We approached the early diagnosis of gastric infiltrating carcinoma, scirrhous cancer, by a retrospective study of 19 patients, together with a prospective study of a single patient, by reexamination and follow-up of gastric roentgenographs and endoscopic films. This study suggests that an early feature of this type o...

journal_title：Journal of clinical gastroenterology

authors： Kohli Y,Takeda S,Kawai K

更新日期：1981-03-01 00:00:00

abstract：:Ammonia is a neurotoxin that is normally cleared by the intact liver and if not, hyperammonemia results in hepatic encephalopathy. Hyperammonemia may be owing to primary or secondary causes. Early diagnosis is important to prevent permanent brain damage. Advanced malignancy involving the liver is associated with hyper...

journal_title：Journal of clinical gastroenterology

authors： Broadbridge V,Townsend A,Pittman K,Kimber R,Patterson W,Sukumaran S,Price TJ

更新日期：2010-09-01 00:00:00

abstract：:Jejunal varices were a cause of recurrent gastrointestinal hemorrhage in an 18-year-old man with common variable immunodeficiency and nodular lymphoid hyperplasia of the small intestine. Despite numerous procedures, including upper gastrointestinal endoscopy, colonoscopy, arteriography, and exploratory laparotomy no a...

journal_title：Journal of clinical gastroenterology

authors： Freiman JS,Gallagher ND

更新日期：1985-10-01 00:00:00

abstract：:Copper deficiency is an uncommonly reported complication of celiac disease that has not received much attention in recent years. Copper deficiency may result in anemia and thrombocytopenia and also irreversible myeloneuropathy if it is not detected and treated appropriately. The prevalence of copper deficiency in pati...

journal_title：Journal of clinical gastroenterology

authors： Halfdanarson TR,Kumar N,Hogan WJ,Murray JA

更新日期：2009-02-01 00:00:00

abstract：:The role of the anorectal band in the genesis of hemorrhoids is studied. The anorectal band is a fibroepithelial tube which is a remnant of the anorectal sinus. Seventy-six hemorrhoid patients and 32 controls were studied. Rectal neck pressure recording was done for all subjects. Two biopsies were taken from the lower...

journal_title：Journal of clinical gastroenterology

authors： Shafik A

更新日期：1984-04-01 00:00:00

abstract：:We looked for factors predicting the therapeutic outcome in 66 patients with severe ulcerative colitis treated with intravenous hydrocortisone or corticotropin (ACTH) for 10 days. Patients were randomized before therapy within strata defined by whether they had received oral corticosteroids continuously before the stu...

journal_title：Journal of clinical gastroenterology

authors： Meyers S,Lerer PK,Feuer EJ,Johnson JW,Janowitz HD

更新日期：1987-02-01 00:00:00

abstract：:The clinicopathologic findings in eight Mexican patients with immunoproliferative small intestinal disease (IPSID) are analyzed. Four of these cases have been previously reported and the remainder were found in a retrospective review of 42 lymphoproliferative disorders of the small bowel (9.5% of the cases at our inst...

journal_title：Journal of clinical gastroenterology

authors： Arista-Nasr J,González-Romo MA,Mantilla-Morales A,Lazos-Ochoa M,Ortiz-Hidalgo C

更新日期：1994-01-01 00:00:00

abstract：:Helicobacter pylori infection has proven to be extraordinarily difficult to eradicate. Antimicrobial monotherapies have been particularly disappointing, with most eradication rates in the range of 0-15%. Clarithromycin has potential advantages over other macrolides to which H. pylori is susceptible because of its acid...

journal_title：Journal of clinical gastroenterology

authors： Graham DY,Opekun AR,Klein PD

更新日期：1993-06-01 00:00:00

abstract：:Multiple lymphomatous polyposis is very rare. We report two cases affecting duodenum, small intestine and colon/rectum, both with extensive disease, making radical surgery impossible and chemotherapy the treatment of choice. One patient died 23 days after initial treatment of myocardial infiltration, and the other is ...

journal_title：Journal of clinical gastroenterology

authors： Norum J,Hovde O,Stalsberg H

更新日期：1994-09-01 00:00:00

abstract：:The authors report a rare case of hepatocellular carcinoma (HCC) that developed 6 years after a sustained and complete response to interferon (IFN) therapy for chronic hepatitis C. A 61-year-old Japanese man presented with a mass in the liver that was diagnosed as HCC. Six years earlier he was treated with IFN-alpha a...

journal_title：Journal of clinical gastroenterology

authors： Yamaguchi K,Omagari K,Kinoshita H,Yoshioka S,Furusu H,Takeshima F,Nanashima A,Yamaguchi H,Kohno S

更新日期：1999-09-01 00:00:00

abstract：:We investigated whether autoimmune cholangitis (AC) has specific features that constitute an entity other than primary biliary cirrhosis (PBC). We compared clinical, laboratory, and liver biopsy features; response to treatment; and the follow-up of two groups of patients. The first group comprised seven patients with ...

journal_title：Journal of clinical gastroenterology

authors： Sánchez-Pobre P,Castellano G,Colina F,Dominguez P,Rodriguez S,Canga F,Herruzo JA

更新日期：1996-10-01 00:00:00

abstract：:The recognition of Helicobacter pylori (H. pylori) as a major cause of gastroduodenal diseases has led to the use of antibiotics to treat these diseases. However, antibiotics used alone are not very effective, and adjuvant therapy is required. The most potent adjuvant therapy consists of increasing the stomach pH with...

journal_title：Journal of clinical gastroenterology

authors： Mégraud F

更新日期：1995-01-01 00:00:00

abstract：:5-Fluorouracil (5-FU), in association with leucovorin (LV), is the most used chemotherapy agent in the treatment of colorectal cancer. Response rate, as well as side-effect incidence, increases with the dose intensity of regimens that are used. The most common dose-limiting toxicity for 5-FU/LV modulation is diarrhea....

journal_title：Journal of clinical gastroenterology

authors： Daniele B,Secondulfo M,De Vivo R,Pignata S,De Magistris L,Delrio P,Palaia R,Barletta E,Tambaro R,Carratù R

更新日期：2001-03-01 00:00:00

abstract：:Between 1984 and 1992, 14 cases of "secondary" achalasia were diagnosed at our institution, five due to malignancy and nine as a result of esophageal or paraesophageal surgery. Preoperative manometry had excluded preexistent achalasia in eight of nine of the latter patients. Dysphagia developed immediately postoperati...

journal_title：Journal of clinical gastroenterology

authors： Ellingson TL,Kozarek RA,Gelfand MD,Botoman AV,Patterson DJ

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:The impact of methicillin-resistant Staphylococcus aureus (MRSA) colonization of percutaneous endoscopic gastrostomy (PEG) sites on morbidity and mortality is uncertain. AIM:We investigated the impact of known prior MRSA colonization on the incidence of symptomatic PEG site wound infection and mortality. M...

journal_title：Journal of clinical gastroenterology

authors： Mainie I,Loughrey A,Watson J,Tham TC

更新日期：2006-04-01 00:00:00

abstract：:Diverticular disease includes a spectrum of conditions sharing the underlying pathology of acquired diverticula of the colon: symptomatic uncomplicated diverticular disease, recurrent symptomatic uncomplicated diverticular disease, and complicated diverticular disease. Goals of therapy in diverticular disease should b...

journal_title：Journal of clinical gastroenterology

authors： Di Mario F,Comparato G,Fanigliulo L,Aragona G,Cavallaro LG,Cavestro GM,Franzé A

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Inactive and active phases of hepatitis B e antigen-negative chronic hepatitis B virus (HBV) infection are diagnosed by serum HBV DNA levels, with cutoff at 2000 IU/mL. However, it is difficult to distinguish inactive carriers at a single time point because HBV DNA levels can transiently decrease to <2000 IU...

journal_title：Journal of clinical gastroenterology

authors： Yim SY,Um SH,Jung JY,Seo YS,Yim HJ,Ryu HS,Chun HJ,Jeen YT,Kim CD,Keum B,Lee HS

更新日期：2014-02-01 00:00:00

abstract：GOALS:To review the published experience with acute pancreatitis in childhood. STUDY:Computerized search of the English medical literature since 1965 using MEDLINE. RESULTS:Details of 589 patients were reviewed. Mean age was 9.2 +/- 2.4 years (range: 1 week to 21 years). Male to female ratio was 1.2. Etiologies inclu...

journal_title：Journal of clinical gastroenterology

authors： Benifla M,Weizman Z

更新日期：2003-08-01 00:00:00

abstract：:A 65-year-old Japanese woman had primary biliary cirrhosis (PBC) and chronic pancreatitis associated with ulcerative colitis. The association of PBC and ulcerative colitis may prove to be valid. ...

journal_title：Journal of clinical gastroenterology

authors： Kato Y,Morimoto H,Unoura M,Kobayashi K,Hattori N,Nakanuma Y

更新日期：1985-10-01 00:00:00

abstract：:A 26-year-old man had a massive intraabdominal hemorrhage from a hepatocellular adenoma (HCA). The tumor arose within a liver that demonstrated generalized nodular regenerative hyperplasia. The patient had no factors predisposing to either HCA or nodular regenerative hyperplasia (NRH) of the liver. Although rare, HCA ...

journal_title：Journal of clinical gastroenterology

authors： Nguyen TD,Oakes D,Fogel MR,Williams L,Sherck JP,Kozar M

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:There has been constant speculation about the association between metabolic syndrome (MetS) and colorectal neoplasia (CN); however, the published results are conflicting. The aims of this study are to conduct a systematic search, and assess the literature to determine the available evidence on the associatio...

journal_title：Journal of clinical gastroenterology

authors： Jinjuvadia R,Lohia P,Jinjuvadia C,Montoya S,Liangpunsakul S

更新日期：2013-01-01 00:00:00

abstract：:A 53-year-old white woman developed diabetes mellitus, migratory erythema, and anemia, clinical features suggesting the presence of a "glucagonoma." Ten years earlier, after laparotomy and pancreatic biopsy, she had been told that she had an inoperable pancreatic carcinoma. Review of that biopsy together with current ...

journal_title：Journal of clinical gastroenterology

authors： Pitchumoni CS,Thelmo W,Ahmed KS,Kumar A,Davidian M,Einhorn R,Adler J,McCarthy J

更新日期：1979-09-01 00:00:00

abstract：:Technetium-99m-diethylenetriaminepentaacetic acid-galactosyl-human serum albumin (Tc-GSA) is a receptor binding agent, specific for asialoglycoprotein receptor, that resides exclusively on the plasma membrane of mammalian hepatocytes. The usefulness of Tc-GSA for estimating the hepatic functional reserve was retrospec...

journal_title：Journal of clinical gastroenterology

authors： Fujioka H,Kawashita Y,Kamohara Y,Yamashita A,Mizoe A,Yamaguchi J,Azuma T,Furui J,Kanematsu T

更新日期：1999-06-01 00:00:00

abstract：GOALS:To describe current hepatitis C virus (HCV) treatment practices in the United States and identify physician characteristics associated with the use of first generation direct-acting antivirals (DAAs). BACKGROUND:HCV treatment practice patterns have not been assessed after the introduction of DAA, which are now c...

journal_title：Journal of clinical gastroenterology

authors： Chen EY,Lee WM,Hynan LS,Singal AG

更新日期：2013-10-01 00:00:00

abstract：:Sucralfate binds to duodenal and gastric ulcers and to gastric erosions produced by ethanol and anti-inflammatory drugs. The affinity of sucralfate for defective mucosa is explained by the drug's viscous adhesiveness and the formation of polyvalent bridges between the negatively charged sucralfate polyanions and posit...

journal_title：Journal of clinical gastroenterology

authors： Nagashima R

更新日期：1981-01-01 00:00:00

abstract：:Chylous ascites remains rare as a complication of surgical intervention. Although therapeutic manoeuvres to control chylous ascites have been developed over the past 20 years, its pathophysiology is poorly understood. Conservative approaches involving dietary restriction of long-chain triglycerides and salt, together ...

journal_title：Journal of clinical gastroenterology

authors： Ohri SK,Patel T,Desa LA,Spencer J

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:The diagnosis of chronic pancreatitis (CP) remains challenging. Endoscopic ultrasound (EUS) and magnetic resonance cholangiopancreatography (MRCP) have been proposed as highly accurate diagnostic modalities. Although endoscopic retrograde cholangiopancreatography (ERCP) has been previously used as a gold sta...

journal_title：Journal of clinical gastroenterology

authors： Pungpapong S,Wallace MB,Woodward TA,Noh KW,Raimondo M

更新日期：2007-01-01 00:00:00