Acute pancreatitis in childhood: analysis of literature data.

Abstract:

GOALS:To review the published experience with acute pancreatitis in childhood. STUDY:Computerized search of the English medical literature since 1965 using MEDLINE. RESULTS:Details of 589 patients were reviewed. Mean age was 9.2 +/- 2.4 years (range: 1 week to 21 years). Male to female ratio was 1.2. Etiologies included (n = 589): idiopathic (23%), trauma (22%), structural anomalies (15%), multisystem disease (14%), drugs and toxins (12%), viral infections (10%), hereditary (2%) and metabolic disorders (2%). Diagnosis was based most often on abnormal abdominal ultrasonography (81%) and on elevated serum amylase levels (63%). Radiograph findings were helpful in 34%. In 16% of the patients the diagnosis was based only on laparotomy. Mean hospital stay was 13.2 +/- 2.4 days and TPN was required in 28% of the patients. In 24% of the subjects a surgical intervention was indicated. Recurrence was reported in 9%, most of them with idiopathic and structural etiologies. Fatal outcome was described in 9.7% of the patients. CONCLUSIONS:Acute pancreatitis of childhood, although considered sometimes as a minor disorder, carries significant morbidity and mortality. Therefore, pediatricians should be more aware of this illness.

journal_name

J Clin Gastroenterol

authors

Benifla M,Weizman Z

doi

10.1097/00004836-200308000-00015

subject

Has Abstract

pub_date

2003-08-01 00:00:00

pages

169-72

issue

2

eissn

0192-0790

issn

1539-2031

journal_volume

37

pub_type

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