Circulating interferon-like activity in inflammatory bowel disease.

Abstract:

:Inflammatory bowel diseases (IBD) has been characterized as having an autoimmune background. We studied the presence of immune interferon in the sera of a small number of patients with IBD. Antiviral activity was detectable in the sera of our patients with well-controlled IBD but it was mainly weak-positive (50% inhibition of virus CPE in a dilution of 1:10 per 0.2 ml of serum). The antiviral activity varied according to the sensitivity of the cell line used. The human amnion cells Wish (81%) and the human embryonic Intestine-407 (73%) were more sensitive.

journal_name

J Clin Gastroenterol

authors

Christodoulopoulou G,Havredaki M,Christodoulopoulos J

doi

10.1097/00004836-198610000-00008

subject

Has Abstract

pub_date

1986-10-01 00:00:00

pages

534-7

issue

5

eissn

0192-0790

issn

1539-2031

journal_volume

8

pub_type

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