Effect of chemotherapy with 5-fluorouracil on intestinal permeability and absorption in patients with advanced colorectal cancer.

abstract：:The synthesis of prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) in colonic mucosal cells was investigated in 7 patients and 10 controls. Biopsies obtained from the descending colon were isolated biochemically by a special technique and the suspension of isolated colonic cells was incubated during 45 min. Compared w...

journal_title：Journal of clinical gastroenterology

authors： Baumeister B,Schmidt C,Helisch A,Kipnowski J

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND & AIMS:Cyclic vomiting syndrome (CVS) is characterized by episodes of nausea and vomiting separated by symptom-free intervals. Rome IV guidelines have now distinguished CVS from other disorders such as cannabinoid hyperemesis. The pathogenesis of CVS, however, is poorly understood. Limited data exist on gast...

journal_title：Journal of clinical gastroenterology

authors： Kamal A,Sarvepalli S,Selvakumar P,Lopez R,Radhakrishnan K,Gabbard S

更新日期：2020-10-01 00:00:00

abstract：:We compared the diagnostic accuracy of a new immunological marker of celiac sprue (CS), the antijejunum antibody (JAB), with that of antigliadin (AGA) and antiendomysium (EmA) antibodies. One hundred untreated adults with biopsy-proven CS, 52 healthy controls, and 57 patients with inflammatory bowel disease, lymphoma ...

journal_title：Journal of clinical gastroenterology

authors： Sategna-Guidetti C,Grosso S,Bruno M,Grosso SB

更新日期：1995-01-01 00:00:00

abstract：:Etiology of inflammatory bowel disease (IBD) is not yet completely understood, but it is hypothesized that a disruption of the immune tolerance to gut microbiota, due to several potential factors like an abnormal gut microbiota composition and activity, may lead to IBD occurrence. Manipulation of the intestinal microb...

journal_title：Journal of clinical gastroenterology

authors： Scarpato E,Russo M,Staiano A

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:Recently, an increasing interest to nonmotor symptoms of Parkinson disease (PD) has shown. Gastrointestinal dysfunction is a prominent nonmotor manifestation of PD and precedes motor symptoms for several years. Neuropathologic studies show early accumulation of α-synuclein (α-SYN) in Lewy neurites and Lewy...

journal_title：Journal of clinical gastroenterology

authors： Mrabet S,Ben Ali N,Achouri A,Dabbeche R,Najjar T,Haouet S,Belal S

更新日期：2016-10-01 00:00:00

abstract：:Food sensitivities are constantly increasing in "westernized" countries and may pose serious health risks to sensitized individuals. Severe allergy episodes have also been reported after the intake of probiotic products containing milk protein residues, especially in children. The need for safe and effective probiotic...

journal_title：Journal of clinical gastroenterology

authors： Mogna G,Strozzi GP,Mogna L

更新日期：2008-09-01 00:00:00

abstract：:In a prospective series of 284 upper gastrointestinal (GI) endoscopies, outcome was evaluated by a cost-benefit analysis. Two-thirds of the endoscopies had a negative result, or a diagnosis was found which was not worth the costs of the endoscopy. The overall diagnostic gain of 284 endoscopies, however, outweighed the...

journal_title：Journal of clinical gastroenterology

authors： Sonnenberg A,Blum AL

更新日期：1982-04-01 00:00:00

abstract：:Occult gastrointestinal bleeding frequently frustrates clinicians' attempts to locate the source. Foci of hemorrhage within the small bowel are often found only at laparotomy and can be attributed to Meckel's diverticula, carcinomas, or less frequently, pulsion-type diverticula. We report our experience with two patie...

journal_title：Journal of clinical gastroenterology

authors： Rodriguez HE,Ziauddin MF,Quiros ED,Brown AM,Podbielski FJ

更新日期：2001-11-01 00:00:00

abstract：:Since the first fiberoptic instruments, gastrointestinal endoscopy has shaped the field of gastroenterology and is now a key diagnostic and therapeutic tool. Compared with the initial fiberoptic endoscopes state-of-the-art optical chips (or charge-coupled device technology) allowed a quantum leap in image quality. Des...

journal_title：Journal of clinical gastroenterology

authors： Holtmann GJ,Huelsen A,Shah A,Hourigan LF,Morrison M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The standard of care for managing pancreaticobiliary disease in altered Roux-en-Y gastric bypass patients is laparoscopy-assisted endoscopic retrograde cholangiopancreatography (LA-ERCP), but is limited by cost and adverse events. Recently a minimally invasive, completely endoscopic approach using e...

journal_title：Journal of clinical gastroenterology

authors： Kedia P,Tarnasky PR,Nieto J,Steele SL,Siddiqui A,Xu MM,Tyberg A,Gaidhane M,Kahaleh M

更新日期：2019-04-01 00:00:00

abstract：:Copper deficiency is an uncommonly reported complication of celiac disease that has not received much attention in recent years. Copper deficiency may result in anemia and thrombocytopenia and also irreversible myeloneuropathy if it is not detected and treated appropriately. The prevalence of copper deficiency in pati...

journal_title：Journal of clinical gastroenterology

authors： Halfdanarson TR,Kumar N,Hogan WJ,Murray JA

更新日期：2009-02-01 00:00:00

abstract：:Insulin resistance is an integral part of the underlying pathophysiology in most patients with nonalcoholic fatty liver disease (NAFLD). Insulin-sensitizing agents are therefore likely to be of key importance in the treatment of this disorder, especially in the histologically more severe form known as nonalcoholic ste...

journal_title：Journal of clinical gastroenterology

authors： Caldwell SH,Argo CK,Al-Osaimi AM

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Portal or bridging fibrosis is an indication for antiviral treatment in patients with chronic hepatitis B (CHB). An early marker predictive of liver fibrosis in hepatitis B e antigen (HBeAg)-negative CHB patients can alert clinicians to plan for treatment before disease progression. GOALS:To predict early a...

journal_title：Journal of clinical gastroenterology

authors： Lee IC,Chan CC,Huang YH,Huo TI,Chu CJ,Lai CR,Lee PC,Su CW,Hung HH,Wu JC,Lin HC,Lee SD

更新日期：2011-03-01 00:00:00

abstract：GOAL:To study the rate at which Helicobacter pylori infection is treated in an immigrant cohort after diagnosis by esophagogastroduodenoscopy (EGD). BACKGROUND:Gastric cancer is the second leading cause of cancer death worldwide, and is especially prevalent in East Asia; immigrants from this part of the world remain a...

journal_title：Journal of clinical gastroenterology

authors： Cho A,Chaudhry A,Minsky-Primus L,Tso A,Perez-Perez G,Diehl DL,Marcus SG,Gany FM

更新日期：2006-01-01 00:00:00

abstract：:Ingestion of a corrosive substance can produce severe injury to the gastrointestinal tract and can even result in death. The degree and extent of damage depends on several factors like the type of substance, the morphologic form of the agent, the quantity, and the intent. In the acute stage, perforation and necrosis m...

journal_title：Journal of clinical gastroenterology

authors： Ramasamy K,Gumaste VV

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:To assess the therapeutic efficacy of 5-aminosalicylic acid (5-ASA) in patients with colonic diverticular disease performing a systematic review of the literature. DATA SOURCES:Cochrane Trial Register (until Issue 4, 2008), Medical Literature Analysis and Retrieval System Online (1966 to October 1, 2008), Ex...

journal_title：Journal of clinical gastroenterology

authors： Gatta L,Vakil N,Vaira D,Pilotto A,Curlo M,Comparato G,Leandro G,Ferro U,Lera M,Milletti S,Di Mario F

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:There was some ambiguity in the recent guidelines on the use of capsule endoscopy (CE) in cases of iron deficiency anemia (IDA). GOAL:We aimed to examine the yield of CE in diagnosing the cause of IDA and to define clinical parameters that predict higher diagnostic yields. MATERIALS AND METHODS:A total of ...

journal_title：Journal of clinical gastroenterology

authors： Stone J,Grover K,Bernstein CN

更新日期：2020-05-01 00:00:00

abstract：:In the past there has been reliance on heartburn and acid regurgitation as the cardinal symptoms of gastro-esophageal reflux. Now it is recognized that diverse additional symptoms including extraesophageal manifestations are essential components of gastroesophageal reflux disease (GERD). Furthermore, previous reliance...

journal_title：Journal of clinical gastroenterology

authors： Modlin IM,Malfertheiner P,Hunt RH,Armstrong D,Holtmann G,Quigley EM,Spechler SJ

更新日期：2007-03-01 00:00:00

abstract：:We describe a patient with primary biliary cirrhosis associated with Graves' disease and discuss the possible autoimmune connections between the two disorders. ...

journal_title：Journal of clinical gastroenterology

authors： Nieri S,Riccardo GG,Salvadori G,Surrenti C

更新日期：1985-10-01 00:00:00

abstract：:Upper gastrointestinal endoscopy is the most sensitive diagnostic test in patients with upper gastrointestinal symptoms. Endoscopy performed by trained examiners, however, still misses lesions. Single-contrast upper gastrointestinal x-ray adds little new information to a complete endoscopic examination by a trained en...

journal_title：Journal of clinical gastroenterology

authors： Tedesco FJ

更新日期：1981-01-01 00:00:00

abstract：GOAL:We hypothesized that sleeping left-side down with the head/torso elevated reduces recumbent gastroesophageal reflux (GER). BACKGROUND:Previous studies show that sleeping with head of bed elevated or on wedge reduces GER and lying left-side down reduces GER versus right-side down and supine. No prior studies have ...

journal_title：Journal of clinical gastroenterology

authors： Person E,Rife C,Freeman J,Clark A,Castell DO

更新日期：2015-09-01 00:00:00

abstract：:Abnormalities in esophageal peristaltic function and acid clearance appear to be responsible for prolonged esophageal acid exposure, a major determinant of the reflux esophagitis and esophageal stricture. We evaluated esophageal motility by manometry in 50 healthy controls and in 35 symptomatic reflux patients before,...

journal_title：Journal of clinical gastroenterology

authors： Grande L,Lacima G,Ros E,Pujol A,Garcia-Valdecasas JC,Fuster J,Visa J,Pera C

更新日期：1991-02-01 00:00:00

abstract：:The use of probiotics in diarrheal diseases of children is increasing. Probiotics, mostly lactic acid bacteria such as Lactobacilli and Bifidobacteria, but also the yeast Saccharomyces boulardii, have been tried in many double-blinded, randomized, placebo-controlled studies, and several well-conducted meta-analyses ar...

journal_title：Journal of clinical gastroenterology

authors： Guandalini S

更新日期：2006-03-01 00:00:00

abstract：:In pneumatosis cystoides intestinalis the air sacs are generally small and the mesentery is rarely involved. We describe a 23-year-old woman with mixed connective tissue disease and known esophageal ulcer who developed hematemesis and abdominal distention. Colonoscopy showed pneumatosis coli. A computed tomography (CT...

journal_title：Journal of clinical gastroenterology

authors： Lanspa SJ,Liu MW,Jenkins HJ Jr

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is no consensus concerning small bowel preparation before capsule endoscopy (CE). This study evaluated the effects of 4 regimens on small bowel cleansing and diagnostic yield. METHODS:Patients were randomly divided into 4 groups. Group A consumed a clear liquid diet after lunch on the da...

journal_title：Journal of clinical gastroenterology

authors： Chen HB,Huang Y,Chen SY,Song HW,Li XL,Dai DL,Xie JT,He S,Zhao YY,Huang C,Zhang SJ,Yang LN

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Tormentil extracts (TE) have antioxidative properties and are used as a complementary therapy for chronic inflammatory bowel disease. In individual patients with ulcerative colitis (UC) positive effects have been observed. GOALS:To assess the safety, pharmacology, and clinical effects of different doses of ...

journal_title：Journal of clinical gastroenterology

authors： Huber R,Ditfurth AV,Amann F,Güthlin C,Rostock M,Trittler R,Kümmerer K,Merfort I

更新日期：2007-10-01 00:00:00

abstract：:Biopsy and autopsy materials excised from a 69-year-old woman were investigated. Serum carcinoembryonic antigen (CEA) showed a high value of 955 ng/mL. A plateaulike tumor was located in the gastric cardia and fundus to the entire gastric body. It showed severe proliferation and infiltration from the mucosa to the ser...

journal_title：Journal of clinical gastroenterology

authors： Morii S,Oka K,Hakozaki H,Nihei T,Mori N

更新日期：1999-07-01 00:00:00

abstract：:The clinicopathologic features of 221 patients with intestinal-type (IT) gastric cancer were compared retrospectively with those of 290 diffuse type (DT). Intestinal type was characterized by an older mean age (65.0 +/- 10.8 years vs. 56.2 +/- 13 years), a higher male-female ratio (2.56 vs. 1.06), predominance of bloo...

journal_title：Journal of clinical gastroenterology

authors： Wu MS,Yang KC,Shun CT,Hsiao TJ,Lin CC,Wang HP,Chuang SM,Lee WJ,Lin JT

更新日期：1997-12-01 00:00:00

abstract：:Two patients with primary malignant lymphoma underwent spontaneous regression. One was a 40-year-old woman with a large ulcerating tumor on the greater curvature of the gastric antrum. This tumor shrank spontaneously, leaving only a small shallow ulcer. The resected specimen showed a minute focus of malignant lymphoma...

journal_title：Journal of clinical gastroenterology

authors： Shigematsu A,Iida M,Lien GS,Imamura T,Okada M,Fuchigami T,Fujishima M,Itoh H,Iwashita A

更新日期：1989-10-01 00:00:00

abstract：:Gastric cancer is often diagnosed in middle-aged patients undergoing upper gastrointestinal endoscopy for abdominal complaints or constitutional symptoms, such as dyspepsia, vomiting or anorexia, weight loss, anemia, jaundice, and ascites. Sometimes, all of these symptoms may be absent, and gastric cancer is diagnosed...

journal_title：Journal of clinical gastroenterology

authors： Perri F,Bisceglia M,Giannatempo GM,Andriulli A

更新日期：2001-07-01 00:00:00