Saxagliptin is similar in glycaemic variability more effective in metabolic control than acarbose in aged type 2 diabetes inadequately controlled with metformin.

abstract：AIM:To assess the relationship between acarbose and hepatotoxicity, cardiovascular disease (CVD), and mortality among type 2 diabetes (T2D) patients with end-stage renal disease (ESRD). METHODS:32,531 T2D patients with ESRD were identified from Taiwan's National Health Insurance Research Database in 2000~∼2012 and fol...

journal_title：Diabetes research and clinical practice

authors： Lin WH,Yang CY,Kuo S,Kuo TH,Roan JN,Li CY,Wang MC,Ou HT

更新日期：2020-10-06 00:00:00

abstract：:Use of a real-time bedside glucose monitor was analyzed during the course of management of diabetic ketoacidosis (DKA) in children. Simultaneous determinations of blood glucose were obtained, using three methods: bedside glucose meter (One Touch II), laboratory glucose analyzer (YSI 2300 STAT), and a real-time bedside...

journal_title：Diabetes research and clinical practice

authors： Coss-Bu JA,Jefferson LS,Stone-McCord S,Ou CN,Watrin C,Sachdeva R,Copeland KC

更新日期：1999-06-01 00:00:00

abstract：:While use of intensive insulin therapy has proven effective for reducing risk of long-term complications of hyperglycemia in people with diabetes, overnight hypoglycemia remains a significant barrier to intensive therapy. Findings from numerous studies indicate that nocturnal hypoglycemia is a frequent event among pat...

journal_title：Diabetes research and clinical practice

authors： Yale JF

更新日期：2004-09-01 00:00:00

abstract：AIMS:Screening for depression is recommended internationally. The World Health Organization's 5-item Well-being Index (WHO-5) is used clinically to screen for depression but its empirical suitability for this purpose is not well documented. We investigated the psychometric properties of the WHO-5 and its suitability fo...

journal_title：Diabetes research and clinical practice

authors： Halliday JA,Hendrieckx C,Busija L,Browne JL,Nefs G,Pouwer F,Speight J

更新日期：2017-10-01 00:00:00

abstract：:C57BL/KsJ mice carrying homozygous db/db mutation (db/db mice) are characterized by extreme obesity and early onset of hyperglycemia. In an attempt to rectify diabetes of these mice, a pancreatic beta cell line MIN6, which retains glucose-inducible insulin secretion, was transplanted subcutaneously into the back of th...

journal_title：Diabetes research and clinical practice

authors： Inada S,Kaneko S,Suzuki K,Miyazaki J,Asakura H,Fujiwara M

更新日期：1996-05-01 00:00:00

abstract：AIMS:Type 2 diabetes mellitus (T2DM) is associated with subtle cognitive changes, but also with more severe stages of cognitive dysfunction, including mild cognitive impairment (MCI) and dementia. For these severe stages, it is uncertain which domains are primarily affected and if all patients with impairment are captu...

journal_title：Diabetes research and clinical practice

authors： Groeneveld ON,van den Berg E,Rutten GEHM,Koekkoek PS,Kappelle LJ,Biessels GJ,COG-ID study group.

更新日期：2018-08-01 00:00:00

abstract：AIMS:TNF-α is a diabetogenic cytokine associated with adverse outcomes during pregnancy that can be counterbalanced by IL-10. We have investigated IL-10 and TNF-α balance at maternal and placental levels in hyperglycemia-associated pregnancies. METHODS:One hundred and ninety-two pregnant women participated, which incl...

journal_title：Diabetes research and clinical practice

authors： Moreli JB,Corrêa-Silva S,Damasceno DC,Sinzato YK,Lorenzon-Ojea AR,Borbely AU,Rudge MV,Bevilacqua E,Calderon IM

更新日期：2015-03-01 00:00:00

abstract：:Circulating insulin antibodies at birth and the degree of maternal metabolic control were measured in 68 infants of insulin-treated diabetic mothers. Their correlation with neonatal B cell function and with the clinical features of the infants was evaluated in order to better understand their influence on fetal outcom...

journal_title：Diabetes research and clinical practice

authors： Fallucca F,Maldonato A,Iavicoli M,Di Rollo G,Di Biase N,Napoli A,De Vecchis P,Sciullo E,Gerlinì G,Pachi A

更新日期：1989-11-06 00:00:00

abstract：:The effects of glucose (16.7 mM), potassium (50 mM), forskolin (20 microM), dibutyryl cyclic AMP (1 mM) and arachidonic acid (82 microM) upon insulin release and cytosolic free calcium concentrations ([Ca2+]i) were investigated in normal rat pancreatic islets. Potassium, forskolin and dibutyryl cyclic AMP significantl...

journal_title：Diabetes research and clinical practice

authors： Draznin B,Metz SA,Sussman KE,Leitner JW

更新日期：1987-09-01 00:00:00

abstract：:Expansion of the glomerular mesangium is a consistent finding of diabetic nephropathy. Negatively charged proteoglycans are an integral part of the mesangium and their synthesis and degradation is disturbed in many forms of glomerulosclerosis. The metabolism of ascorbic acid (AA), which plays an important role in extr...

journal_title：Diabetes research and clinical practice

authors： McAuliffe AV,Fisher EJ,McLennan SV,Yue DK,Turtle JR

更新日期：1997-08-01 00:00:00

abstract：AIMS:The present study aimed to evaluate effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor (DPP-4I), on cognitive functions in elderly diabetic patients with and without cognitive impairment. METHODS:253 elderly patients with type 2DM, were enrolled in this prospective and observational study. After comprehens...

journal_title：Diabetes research and clinical practice

authors： Isik AT,Soysal P,Yay A,Usarel C

更新日期：2017-01-01 00:00:00

abstract：AIMS:The purpose of this study was to evaluate whether carotid IMT (cIMT) identified using automated software is associated with HbA1c in Japanese patients with coronary artery disease. METHODS:370 consecutive patients (males 218; median age 69 years ± 11) who underwent carotid-US and first coronary angiography were p...

journal_title：Diabetes research and clinical practice

authors： Saba L,Ikeda N,Deidda M,Araki T,Molinari F,Meiburger KM,Acharya UR,Nagashima Y,Mercuro G,Nakano M,Nicolaides A,Suri JS,Fellow AIMBE.

更新日期：2013-06-01 00:00:00

abstract：AIMS:To validate and culturally adapt the Diabetes-specific Quality of Life Brief Clinical Inventory (DQOL-BCI) for the Iranian population. METHODS:After translation - back translation, content validity was assessed utilizing a panel of six experts. Based on a sample of 180 diabetic patients referred to two Diabetics ...

journal_title：Diabetes research and clinical practice

authors： Mirfeizi M,Jafarabadi MA,Toorzani ZM,Mohammadi SM,Azad MD,Mohammadi AV,Teimori Z

更新日期：2012-05-01 00:00:00

abstract：AIMS:To determine the appropriate cutoff value of waist circumference associated with cardiometabolic risk factors in Koreans. METHODS:Clinical and laboratory data on 31,076 Korean adults (age 20-89 years, 40% women) were recorded at regular health check-ups. Receiver operating characteristic curves were used to deter...

journal_title：Diabetes research and clinical practice

authors： Kim HK,Kim CH,Park JY,Lee KU

更新日期：2009-07-01 00:00:00

abstract：AIMS:The aims were to assess effect of a short training programme on non-communicable diseases (NCDs), particularly diabetes on school teachers and also on students who were in turn educated by them. Lifestyle changes made by both groups were assessed 6months later. METHODS:Graduate teachers (n=1017) from 2 districts ...

journal_title：Diabetes research and clinical practice

authors： Selvam S,Murugesan N,Snehalatha C,Nanditha A,Raghavan A,Simon M,Susairaj P,Ramachandran A

更新日期：2017-03-01 00:00:00

abstract：AIMS:To understand the composition of the residual dysglycemia when HbA1c is between 6.5% (48mmol/mol) and 7% (53mmol/mol), representing the definition of diabetes and the recommended treatment goal, respectively. METHODS:One hundred persons with type 2 diabetes and a HbA1c<7% (53mmol/mol), treated with diet alone and...

journal_title：Diabetes research and clinical practice

authors： Monnier L,Colette C,Dejager S,Owens D

更新日期：2014-06-01 00:00:00

abstract：AIMS:Diabetes and its complications have a significant economic impact on individuals and their families, health systems and national economies. METHODS:The direct health expenditure of diabetes was calculated relying on the following inputs: diagnosed and undiagnosed diabetes prevalence estimates, United Nations popu...

journal_title：Diabetes research and clinical practice

authors： Williams R,Karuranga S,Malanda B,Saeedi P,Basit A,Besançon S,Bommer C,Esteghamati A,Ogurtsova K,Zhang P,Colagiuri S

更新日期：2020-04-01 00:00:00

abstract：AIM:Dyslipidaemia may be a risk factor for diabetic kidney disease. We examined prospectively association between the use of statins and development of renal dysfunction in type 2 diabetes. METHODS:A consecutive cohort of 5264 diabetic patient recruited between 1996 and 2005 underwent detailed assessments. Renal dysfu...

journal_title：Diabetes research and clinical practice

authors： Luk AO,Yang X,Ma RC,Ng VW,Yu LW,Lau WW,Ozaki R,Chow FC,Kong AP,Tong PC,Chan JC,So W

更新日期：2010-06-01 00:00:00

abstract：AIM:To determine the possible factors predicting the insulin requirement in pregnancies complicated by gestational diabetes mellitus (GDM). METHOD:A total of 294 patients with GDM diagnosed by the 100-g/3-h oral glucose tolerance test (OGTT) were studied. The following factors were analyzed: maternal age, nulliparity,...

journal_title：Diabetes research and clinical practice

authors： Sapienza AD,Francisco RP,Trindade TC,Zugaib M

更新日期：2010-04-01 00:00:00

abstract：:The effects of castration on diabetes-related renal growth and IGF-I regulation were studied. In the rat, prepubertal castration is associated with a normal or increased surge in plasma insulin-like growth factor I (IGF-I) at the time of 'puberty'. In order to determine the role of sex steroids in the development of d...

journal_title：Diabetes research and clinical practice

authors： Bach LA,Cox AJ,Jerums G

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of telemedicine on GDM service and maternal, and foetal outcomes. METHODS:A systematic review and meta-analysis of randomised controlled trials (RCT) of telemedicine interventions for GDM was conducted. We searched English publications from 01/01/1990 to 31/08/2013, with further new pu...

journal_title：Diabetes research and clinical practice

authors： Rasekaba TM,Furler J,Blackberry I,Tacey M,Gray K,Lim K

更新日期：2015-10-01 00:00:00

abstract：:Normoalbuminuric insulin-dependent diabetic (IDDM) patients may present higher rates of urinary albumin excretion after submaximal exercise at a standard intensity. To evaluate whether the urinary albumin excretion of IDDM patients is increased after maximal and submaximal exercise when exercise intensities are adjust...

journal_title：Diabetes research and clinical practice

authors： Bertoluci MC,Friedman G,Schaan BD,Ribeiro JP,Schmid H

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:To characterize the maternal glycemic response to betamethasone in subjects without diabetes compared to subjects with diabetes. STUDY DESIGN:Blood glucose levels in 22 gravidae without diabetes and 11 gravidae with diabetes were recorded for 48h following betamethasone administration for threatened preterm ...

journal_title：Diabetes research and clinical practice

authors： Jolley JA,Rajan PV,Petersen R,Fong A,Wing DA

更新日期：2016-08-01 00:00:00

abstract：:Mutations of mitochondrial DNA have been found in cardiomyopathic and diabetic patients as well as mitochondrial myopathic patients. Mitochondrial DNA mutations are maternally transmitted. It has also been reported that these mutations can be acquired under the influence of free radicals. This article is a mini-review...

journal_title：Diabetes research and clinical practice

authors： Takeda N

更新日期：1996-07-01 00:00:00

abstract：AIM:Data suggest that 2h hyperglycaemia during an OGTT is less predictive for cardiovascular disease of the glucose "spike" (the difference between the baseline glucose level and the "peak" hyperglycaemia during the test). METHODS:A euinsulinemic hyperglycaemic clamp at 10 and 15mmol/l glucose, with or without vitamin...

journal_title：Diabetes research and clinical practice

authors： Ceriello A,Esposito K,Piconi L,Ihnat M,Thorpe J,Testa R,Bonfigli AR,Giugliano D

更新日期：2008-11-01 00:00:00

abstract：:Amelioration of albuminuria may be related to specific constellations of risk factors including race and dyslipidaemia. Circulating cholesterol could mitigate the beneficial effect of antihypertensive therapy. We assessed whether cholesterol affected the remission of urinary albumin in patients with type 2 diabetes of...

journal_title：Diabetes research and clinical practice

authors： Earle KA,Harry D,Zitouni K

更新日期：2008-01-01 00:00:00

abstract：:This cross-sectional study compared serum lipoprotein (a) [Lp(a)] concentrations in type 1 and type 2 diabetic subjects and examined the determinants of Lp(a) concentrations in both types of diabetes. Serum Lp(a) was measured in 26 type 1 and 107 type 2 diabetic patients and 126 non-diabetic controls. HbA(1c), fasting...

journal_title：Diabetes research and clinical practice

authors： Nawawi HM,Muhajir M,Kian YC,Mohamud WN,Yusoff K,Khalid BA

更新日期：2002-06-01 00:00:00

abstract：:To investigate the evolution and significance of Q waves in type 2 diabetes, we studied 36 patients of mean (+/-S.D.) age 69.9+/-7.1 years from the longitudinal observational Fremantle Diabetes Study (FDS). All had (i) neither history/symptoms of coronary heart disease (CHD) nor pathological Q waves at FDS recruitment...

journal_title：Diabetes research and clinical practice

authors： Kondola S,Davis WA,Dembo LG,Davis TM

更新日期：2008-10-01 00:00:00

abstract：AIMS:To determine if HLA-DP loci independently contribute to classic type 1 diabetes (T1D) of all ages, childhood-onset T1D and latent autoimmune diabetes in adults (LADA) among Chinese Han population. METHODS:A total of 518 patients with classic T1D (Among them 180 participants manifested T1D between 1-14 years), 519...

journal_title：Diabetes research and clinical practice

authors： Xia Y,Li X,Huang G,Lin J,Luo S,Xie Z,Zhou Z

更新日期：2020-12-08 00:00:00

abstract：:We report that mitochondrial DNA (MtDNA) copy numbers are increased in peripheral blood of patients with diabetic nephropathy (DN). Using qPCR for quantitation, we found a 2-4-fold significant increase (p<0.05) in the mean MtDNA values in DN patients vs. healthy controls and diabetics without nephropathy. Increased Mt...

journal_title：Diabetes research and clinical practice

authors： Malik AN,Shahni R,Iqbal MM

更新日期：2009-11-01 00:00:00