The association of HLA-DP loci with autoimmune diabetes in Chinese.

abstract：:Wistar fatty (WF) rats are obese, hyperinsulinemic and hyperglycemic, and thus a model of type 2 diabetes mellitus. Since we have found that insulin specifically inhibits glucagon-induced glycogenolysis in perivenous hepatocytes (PVH) from normal rats, we examined the inhibitory effect of insulin on glucagon-induced g...

journal_title：Diabetes research and clinical practice

authors： Ikezawa Y,Yamatani K,Ohnuma H,Daimon M,Manaka H,Sasaki H

更新日期：2005-08-01 00:00:00

abstract：AIM:A glycated hemoglobin (HbA1c) range of 5.7-6.4% has been included as a category of increased risk for diabetes. We evaluated whether or not it is reasonable to apply this HbA1c range to Koreans. METHODS:A retrospective analysis was conducted among subjects who participated in comprehensive health check-ups annuall...

journal_title：Diabetes research and clinical practice

authors： Bae JC,Rhee EJ,Lee WY,Park SE,Park CY,Oh KW,Park SW,Kim SW

更新日期：2011-08-01 00:00:00

abstract：:Serum paraoxonase (PON) is a high-density lipoprotein-bound enzyme that can prevent oxidation of low-density lipoprotein by hydrolyzing lipid peroxides and thus exert an anti-atherogenic effect. Recent studies have suggested that glutamine(Q isoform)/arginine(R isoform) polymorphism at position 192 of PON(1) gene is a...

journal_title：Diabetes research and clinical practice

authors： Hu Y,Tian H,Liu R

更新日期：2003-07-01 00:00:00

abstract：:We investigated the follow-up status and prognosis of 109 patients with non-insulin-dependent diabetes mellitus aged from 10 to 19 years old (66 males and 43 females). Patients who had not attended hospital for at least 20 months up to the end of September 1990 were regarded as defaulters, and were surveyed by questio...

journal_title：Diabetes research and clinical practice

authors： Kawahara R,Amemiya T,Yoshino M,Miyamae M,Sasamoto K,Omori Y

更新日期：1994-07-01 00:00:00

abstract：AIMS:This study is amid at investigating the associations, and interactions of serum lipid biomarkers with microvascular complications of type 2 diabetes (T2D). METHODS:A nested case-control study was conducted within an ongoing prospective study on patients with T2D. Microvascular complications of T2D including diabe...

journal_title：Diabetes research and clinical practice

authors： Aryan Z,Afarideh M,Ghajar A,Esteghamati S,Esteghamati A,Nakhjavani M

更新日期：2017-11-01 00:00:00

abstract：AIM:Dozens of susceptibility loci have been identified by type 2 diabetes (T2D) genome wide association study (GWAS) in Europeans. In our previous studies, we systematically evaluated the association of 48 susceptibility loci with T2D risk in Chinese Hans. Because dyslipidemia and hyperglycemia are implicated in the pa...

journal_title：Diabetes research and clinical practice

authors： Liu J,Wang L,Qian Y,Dai J,Shen C,Jin G,Hu Z,Shen H

更新日期：2018-05-01 00:00:00

abstract：AIM:To examine changes in patient-reported outcome (PRO) measures in patients with type 2 diabetes (T2DM) on oral agents who initiated insulin (insulin lispro mix 25/75 [LM25] or insulin glargine) in the DURABLE trial (n=580). METHODS:Subjects completed generic and diabetes-specific health-related quality-of-life meas...

journal_title：Diabetes research and clinical practice

authors： Lee LJ,Fahrbach JL,Nelson LM,McLeod LD,Martin SA,Sun P,Weinstock RS

更新日期：2010-08-01 00:00:00

abstract：:The study was to examine the effects of Sanguis draconis ethanol extract (SDEE) on streptozotocin (STZ)- and cytokine-induced β-cell damage. In vitro, SDEE did not cause cytotoxicity below 200 μg/ml, and can prevent STZ (5mM)-induced cell death and apoptosis below 100 μg/ml on RIN-m5F cells. SDEE inhibits IL-1β/IFN-γ-...

journal_title：Diabetes research and clinical practice

authors： Hu CM,Li JS,Cheah KP,Lin CW,Yu WY,Chang ML,Yeh GC,Chen SH,Cheng HW,Choy CS

更新日期：2011-12-01 00:00:00

abstract：:We investigated the preventive effects of ferulic acid (FA) and alpha-tocopherol (AT) on the progression of diabetic nephropathy. Otsuka Long-Evans Tokushima Fatty (OLETF) and Long-Evans Tokushima Otsuka (LETO) rats were used as type 2 diabetes and non-diabetes models, respectively. Two-thirds of the OLETF rats were f...

journal_title：Diabetes research and clinical practice

authors： Fujita A,Sasaki H,Doi A,Okamoto K,Matsuno S,Furuta H,Nishi M,Nakao T,Tsuno T,Taniguchi H,Nanjo K

更新日期：2008-01-01 00:00:00

abstract：:Chronic renal diseases, including diabetic nephropathy, evolve to terminal renal failure by a process leading to progressive parenchimal damage which appears relatively independent of the initial insult. When glomerular permselectivity is lost, proteins filtered through the glomerular capillary, through proximal tubul...

journal_title：Diabetes research and clinical practice

authors： Remuzzi G,Ruggenenti P

更新日期：1998-04-01 00:00:00

abstract：:The Australian Region 8 (Victoria) Diabetes Education and Control Program (DECP) is a community-based program which seeks to integrate ambulatory diabetes education programs into primary health care centres. The overall goal of the DECP is to reduce the human and economic costs of diabetes in a health region which cov...

journal_title：Diabetes research and clinical practice

authors： Gifford S,Zimmet P

更新日期：1986-05-01 00:00:00

abstract：AIMS:To quantify the static and moving cutaneous sensibility threshold of diabetic patients using a neurosensory device for quantitative pressure detection. METHODS:Three hundred thirty-four (n = 334) patients with type 2 diabetes and no previous history of wounds on the feet were studied using the one- and two-point ...

journal_title：Diabetes research and clinical practice

authors： Carvalho VF,Ueda T,Paggiaro AO,Nascimento ARF,Ferreira MC,Gemperli R

更新日期：2019-11-01 00:00:00

abstract：:A community-based cross-sectional study was conducted to assess the utility values associated with varying degrees of diabetic retinopathy (DR) among type 2 diabetics in Kinmen, Taiwan. A total of 725 eligible type 2 diabetics received DR screening during 1999-2002 and then evaluated utility values in 2003. The diagno...

journal_title：Diabetes research and clinical practice

authors： Tung TH,Chen SJ,Lee FL,Liu JH,Lin CH,Chou P

更新日期：2005-06-01 00:00:00

abstract：AIMS:To determine the change in prevalence, incidence and risk factors associated with diabetes and impaired fasting glucose (IFG) in a rural Korean area. METHODS:Initially a total of 1119 subjects (424 men and 695 women) aged 31-99 years were recruited in 1997. Baseline clinical data and various laboratory values wer...

journal_title：Diabetes research and clinical practice

authors： Song KH,Nam-Goomg IS,Han SM,Kim MS,Lee EJ,Lee YS,Lee MS,Yoon S,Lee KU,Park JY

更新日期：2007-12-01 00:00:00

abstract：:The predictive value of hemoglobin A1c (HbA1c) in comparison to fasting plasma glucose (FPG) is evaluated for 5-year incident diabetes (DM), as HbA1c may be more practical than FPG in the screening for DM in the future. Of 1189 non-DM subjects aged 35-89 years old from the Funagata Study, 57 subjects (4.8%) had develo...

journal_title：Diabetes research and clinical practice

authors： Nakagami T,Tajima N,Oizumi T,Karasawa S,Wada K,Kameda W,Susa S,Kato T,Daimon M

更新日期：2010-01-01 00:00:00

abstract：:The purpose of this study was to investigate the effect of both a single dose and daily oral administration for 15 days of the aqueous extract of the aerial part of Chamaemelum nobile (C. nobile) at a dose of 20mg/kg body weight on blood glucose concentrations and basal insulin levels in normal and streptozotocin-indu...

journal_title：Diabetes research and clinical practice

authors： Eddouks M,Lemhadri A,Zeggwagh NA,Michel JB

更新日期：2005-03-01 00:00:00

abstract：:Mutations of mitochondrial DNA have been found in cardiomyopathic and diabetic patients as well as mitochondrial myopathic patients. Mitochondrial DNA mutations are maternally transmitted. It has also been reported that these mutations can be acquired under the influence of free radicals. This article is a mini-review...

journal_title：Diabetes research and clinical practice

authors： Takeda N

更新日期：1996-07-01 00:00:00

abstract：:Thirty diabetics who had been receiving ordinary insulin were switched to S-lente insulin, a new mixture of four parts semilente and six parts ultralente insulin. Eight times a day, we measured the glucose, insulin, and C-peptide (CPR) in their blood. Those with more than 250 mg/dl postprandial glucose were designated...

journal_title：Diabetes research and clinical practice

authors： Ohneda A,Nihei J,Sasaki M

更新日期：1990-01-01 00:00:00

abstract：:Social determinants of health (SDH) impact clinical outcomes and are often poorly described in research trials. Using a validated tool, SDH dimensions were compared between adolescents enrolled and not enrolled into a large diabetes study. We observed that our study cohort reflected a SDH profile mirroring the eligibl...

journal_title：Diabetes research and clinical practice

authors： Inman M,Daneman D,Curtis J,Sochett E,Elia Y,Dunger DB,Deanfield J,Mahmud FH

更新日期：2016-03-01 00:00:00

abstract：:To investigate the involvement of islet amyloid polypeptide (IAPP) and amyloid deposits in the pathophysiology of this disease, we studied the relationship between IAPP-derived amyloid deposition and the clinical features in type 2 diabetes mellitus. We examined pancreata obtained from 37 type 2 diabetic subjects and ...

journal_title：Diabetes research and clinical practice

authors： Ohsawa H,Kanatsuka A,Mizuno Y,Tokuyama Y,Takada K,Mikata A,Makino H,Yoshida S

更新日期：1992-01-01 00:00:00

abstract：:Insulin's indispensible nature is recognised by its inclusion in the World Health Organization's Essential Medicines List. Despite this insulin is still not available on an uninterrupted basis in many parts of the developing world. The International Insulin Foundation has conducted in-country assessments and based on ...

journal_title：Diabetes research and clinical practice

authors： Beran D,Yudkin JS

更新日期：2010-06-01 00:00:00

abstract：AIMS:Central obesity, a prominent feature of metabolic syndrome (MetS), is commonly assessed by gender- and ethnicity-specific waist circumference (WC) cut-off values. Since 2006, the recommended WC cut-offs by the International Diabetes Federation (IDF) for Europeans are used in Iran because of limited data availabili...

journal_title：Diabetes research and clinical practice

authors： Esteghamati A,Ashraf H,Rashidi A,Meysamie A

更新日期：2008-10-01 00:00:00

abstract：:A new insulin sensitivity index was devised on the basis of an autoregressive model and its validity was investigated. Using data from the 75-g oral glucose tolerance test (OGTT), 115 subjects were divided into 3 groups: 40 with normal glucose tolerance, 34 with impaired glucose tolerance, and 41 with type 2 diabetes ...

journal_title：Diabetes research and clinical practice

authors： Kazama Y,Takamura T,Sakurai M,Shindo H,Ohkubo E,Aida K,Harii N,Taki K,Kaneshige M,Tanaka S,Shimura H,Endo T,Kobayashi T

更新日期：2008-01-01 00:00:00

abstract：AIM:To describe the clinical characteristics and risk factors associated with the progression of COVID-19 in elderly diabetes patients. METHODS:This was a retrospective cohort study, including elderly COVID-19 patients admitted to Wuhan Huoshenshan Hospital between February 10 and 13, 2020. Demographic data, medical h...

journal_title：Diabetes research and clinical practice

authors： Zhang P,Wang M,Wang Y,Wang Y,Li T,Zeng J,Wang L,Li C,Gong Y

更新日期：2020-11-21 00:00:00

abstract：:We investigated whether isoprostanes, as a marker of lipid peroxidation, may be involved in the development of impaired glucose tolerance (IGT) or diabetes. Using a nested case-control study, we tracked the changes in isoprostane levels, insulin sensitivity (IS) and beta-cell function (BCF) in Afro-Jamaicans who progr...

journal_title：Diabetes research and clinical practice

authors： Boyne MS,Sargeant LA,Bennett FI,Wilks RJ,Cooper RS,Forrester TE

更新日期：2007-04-01 00:00:00

abstract：INTRODUCTION:Diabetic cardiac autonomic neuropathy (CAN) is potentially life threatening and its severity might further be aggravated by poor glycaemic control. A decrease in Heart rate variability (HRV) is the earliest finding of CAN even at the sub clinical stage. While intensive glycaemic control prevents the develo...

journal_title：Diabetes research and clinical practice

authors： Mba CM,Nganou-Gnindjio CN,Azabji-Kenfack M,Mfeukeu-Kuate L,Dehayem MY,Mbanya JC,Sobngwi E

更新日期：2019-11-01 00:00:00

abstract：:Serum insulin 1 h post-glucose load is examined in this prospective study of 2971 Caucasoid subjects aged > 20 years in 1966 and followed to 1989. The serum insulin levels as a continuous variable show no significant linear association with coronary heart disease (CHD) deaths in either sex after accounting for age by ...

journal_title：Diabetes research and clinical practice

authors： Welborn TA,Knuiman MW,Ward N,Whittall DE

更新日期：1994-11-01 00:00:00

abstract：AIMS:To estimate the real-world effects of offering a group-based lifestyle intervention (GLI) to adults with diabetes. METHODS:This randomized encouragement trial included adult primary care patients in metropolitan Chicago with type 2 diabetes and body mass index ≥24 kg/m2. Participants were randomized to standard c...

journal_title：Diabetes research and clinical practice

authors： Liss DT,Finch EA,Cooper A,Sheth A,Tejuosho AD,Lancki N,Ackermann RT

更新日期：2018-06-01 00:00:00

abstract：AIMS:To evaluate the effect of continuous subcutaneous insulin infusion (CSII) on glycaemic control, hypoglycaemia and emotional distress in adults with type 1 diabetes (T1D) during the first 12 months. METHODS:47 patients were started on CSII as per NICE guidelines. Anthropometric, clinical and biochemical parameters...

journal_title：Diabetes research and clinical practice

authors： Oldham V,Mumford B,Lee D,Jones J,Das G

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:To investigate infection-related mortality and its predictors in Brazilian type 2 diabetic patients. METHODS:It was carried out a long-term prospective study with 471 type 2 diabetic outpatients. Several clinical, laboratory and electrocardiographic variables were recorded at baseline. Predictive factors for...

journal_title：Diabetes research and clinical practice

authors： Cardoso CR,Salles GF

更新日期：2007-01-01 00:00:00