Assessing social determinants of health in a pediatric diabetes clinical research trial: Are recruited subjects representative of the larger clinical population?

abstract：AIMS:To determine the prevalence of inadequate glycemic control and its correlates in a large multicenter survey of Venezuelan patients with diabetes. METHODS:A cross-sectional study in a sample of adult patients with diabetes, attending health centers in Venezuela. Information about diabetes, current medications, com...

journal_title：Diabetes research and clinical practice

authors： Moreira ED Jr,Neves RC,Nunes ZO,de Almeida MC,Mendes AB,Fittipaldi JA,Ablan F,Venezuelan Diabetes Investigators' Group.

更新日期：2010-03-01 00:00:00

abstract：:Increased plasma plasminogen activator inhibitor type 1 (PAI-1), coagulation factor VII (FVII) and fibrinogen levels have been recognized as risk factors for cardiovascular disease. Because a substantially high incidence of cardiovascular disease has been reported in diabetic patients with nephropathy compared with th...

journal_title：Diabetes research and clinical practice

authors： Hirano T,Kashiwazaki K,Moritomo Y,Nagano S,Adachi M

更新日期：1997-04-01 00:00:00

abstract：:Epidemiologic studies of migrant populations provide very promising clues towards understanding the roles of genetics and environmental factors in the etiology of diabetes mellitus. Populations of Japanese ancestry are of particular interest due to marked differences in prevalence rates of non-insulin dependent diabet...

journal_title：Diabetes research and clinical practice

authors： Franco LJ

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:The serum N-terminal fragment of pro brain natriuretic peptide (NT-proBNP) level in type 2 diabetic subjects with or without diabetic nephropathy (DN) is still unclear. We aimed to evaluate the relationship between serum NT-proBNP levels and different stages of diabetic nephropathy, and identify probable fact...

journal_title：Diabetes research and clinical practice

authors： Danis R,Ozmen S,Arikan S,Gokalp D,Alyan O

更新日期：2012-03-01 00:00:00

abstract：:Methylglyoxal and other alpha-oxoaldehydes are formed from glycolytic intermediates and may be involved in the development of diabetic microangiopathy. Glyoxalase I and glyoxalase II metabolise methylglyoxal to D-lactic acid, via the intermediate S-D-lactoylglutathione. The activities of the glyoxalase enzymes and the...

journal_title：Diabetes research and clinical practice

authors： Thornalley PJ,Hooper NI,Jennings PE,Florkowski CM,Jones AF,Lunec J,Barnett AH

更新日期：1989-08-01 00:00:00

abstract：:Recent studies indicate that not all diabetic subjects benefit from aspirin therapy. Our objective is to characterize diabetic subjects with aspirin resistance using urine thromboxane, and VerifyNow measures. Our results suggest that cardiovascular disease, microalbuminuria, poor diabetes control, and increased waist ...

journal_title：Diabetes research and clinical practice

authors： Yassine HN,Davis-Gorman G,Stump CS,Thomson SS,Peterson J,McDonagh PF

更新日期：2010-10-01 00:00:00

abstract：:In order to evaluate the prevalence of gestational diabetes mellitus (GDM) and the presence of risk factors for GDM, we conducted a retrospective study of a cohort of Italian women. In addition, we compared universal versus selective screening to validate the ADA's recommendations in our population. From June 1st, 199...

journal_title：Diabetes research and clinical practice

authors： Di Cianni G,Volpe L,Lencioni C,Miccoli R,Cuccuru I,Ghio A,Chatzianagnostou K,Bottone P,Teti G,Del Prato S,Benzi L

更新日期：2003-11-01 00:00:00

abstract：:The increasing proportions of older persons accounting for global populations, and the implications for increasing rates of chronic diseases such as type 2 diabetes mellitus, continue to be a cause of concern for clinicians. Considering that older persons are a very heterogeneous group of individuals, the management o...

journal_title：Diabetes research and clinical practice

authors： Abbatecola AM,Paolisso G

更新日期：2009-12-01 00:00:00

abstract：:A hypothesis that mitochondrial genome itself is the thrifty genome has been advanced, as both its mutation, or quality, and amount in the peripheral blood, or quantity, are found to have close relationship to diabetes mellitus, or more specifically insulin resistance. Mere presence of relationship, however, does not ...

journal_title：Diabetes research and clinical practice

authors： Lee HK

更新日期：2001-12-01 00:00:00

abstract：:The aim of this multicentre study was to investigate the effect--in everyday life--of long term administration of acarbose on parameters of glycaemic control, daily insulin requirements, lipid parameters and tolerability in ambulant type 1 diabetic subjects insufficiently controlled with diet and insulin. Furthermore,...

journal_title：Diabetes research and clinical practice

authors： Sels JP,Verdonk HE,Wolffenbuttel BH

更新日期：1998-08-01 00:00:00

abstract：AIM:The association between thyroid stimulating hormone (TSH) and type 2 diabetes mellitus (T2DM) is well known. However, whether TSH is related to diabetic peripheral neuropathy (DPN) has not been studied. The aim of this study was to explore the relationship between TSH and DPN in Chinese patients with T2DM. METHODS...

journal_title：Diabetes research and clinical practice

authors： Zhao W,Zeng H,Zhang X,Liu F,Pan J,Zhao J,Zhao J,Li L,Bao Y,Liu F,Jia W

更新日期：2016-05-01 00:00:00

abstract：:Proteinuria is a well known risk factor for cardiovascular morbidity. There has been no report on cardiovascular morbidity in Indian NIDDM patients with proteinuria. Hence this study has been undertaken to estimate the prevalence of cardiovascular diseases (CVD) in South Indian NIDDM with proteinuria. We studied two g...

journal_title：Diabetes research and clinical practice

authors： Viswanatham V,Snehalatha C,Mathai T,Jayaraman M,Ramachandran A

更新日期：1998-01-01 00:00:00

abstract：:Potassium (K) channels regulate cellular excitability. Their opening hyperpolarises the membrane potential and induces quiescence whereas their closure produces depolarisation and excitation. One K-channel superfamily includes the delayed rectifier (KV), the A-type (KA) and the large conductance, Ca-sensitive (BKCa) c...

journal_title：Diabetes research and clinical practice

authors： Edwards G,Weston AH

更新日期：1995-08-01 00:00:00

abstract：:We report a 19-year-old woman who had a history of type 1 diabetes with recurrent glycogen accumulation in the liver. During her infantile period she presented with no hepatomegaly nor growth retardation. On admission she was diagnosed with diabetic ketoacidosis (DKA). She also had hepatomegaly and elevated transamina...

journal_title：Diabetes research and clinical practice

authors： Tomihira M,Kawasaki E,Nakajima H,Imamura Y,Sato Y,Sata M,Kage M,Sugie H,Nunoi K

更新日期：2004-08-01 00:00:00

abstract：AIMS:To examine predictors of quality of life gains among people with type 1 diabetes following the Dose Adjustment for Normal Eating (DAFNE) self-management training programme. METHODS:Clinical and questionnaire data were collected from 437 patients from 6 hospital centres before, and 18 months post-DAFNE interventio...

journal_title：Diabetes research and clinical practice

authors： Byrne M,Newell J,Coffey N,O' Hara MC,Cooke D,Dinneen SF

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:We examined the effect of a 14-month progressive resistance training (PRT) program on endothelial function in both a supervised training (Center) group and non-supervised training (Home) group of patients with type 2 diabetes. We studied 28 men and women with type 2 diabetes who participated in a 14-month PRT...

journal_title：Diabetes research and clinical practice

authors： Cohen ND,Dunstan DW,Robinson C,Vulikh E,Zimmet PZ,Shaw JE

更新日期：2008-03-01 00:00:00

abstract：:The study analyzed the clinical background and eating habits of Japanese youth-onset type 2 diabetes. Thirty-six patients with type 2 diabetes (22 males, 14 females) with onset in less than 20-year-old were studied. All patients were negative for anti-glutamic acid decarboxylase (GAD) antibody and islet cell antibody....

journal_title：Diabetes research and clinical practice

authors： Matsui J,Tamasawa N,Tanabe J,Kasai N,Murakami H,Matsuki K,Suda T

更新日期：2005-12-01 00:00:00

abstract：AIMS:We evaluated whether glucose fluctuation (GF) causes vascular endothelial injury and affects glucometabolic factors during lengthy oral glucose tolerance test (OGTT). METHODS:We enrolled consecutive 116 patients with coronary artery disease (CAD) who were performed coronary angiography and 4-h OGTT. Blood samples...

journal_title：Diabetes research and clinical practice

authors： Murata M,Adachi H,Oshima S,Kurabayashi M

更新日期：2017-09-01 00:00:00

abstract：:The prevalence of increased urinary albumin excretion (UAE) (micro- and macroalbuminuria) and its association with diabetic retinopathy (DR) (evaluated by fluorescent angiography), coronary heart disease (CHD), and various related risk factors were studied in 320 type 2 diabetic patients. In this subsample of type 2 d...

journal_title：Diabetes research and clinical practice

authors： Lunetta M,Infantone L,Calogero AE,Infantone E

更新日期：1998-04-01 00:00:00

abstract：:Metabolic syndrome affects approximately one quarter of population in developed countries. Its presence is a major risk for development of both type 2 diabetes (T2DM) and atherosclerosis. The prevalence of cardiovascular disease is 2-3 times higher in individuals with metabolic syndrome than in age-matched controls. M...

journal_title：Diabetes research and clinical practice

authors： Tkác I

更新日期：2005-06-01 00:00:00

abstract：:Chronic renal diseases, including diabetic nephropathy, evolve to terminal renal failure by a process leading to progressive parenchimal damage which appears relatively independent of the initial insult. When glomerular permselectivity is lost, proteins filtered through the glomerular capillary, through proximal tubul...

journal_title：Diabetes research and clinical practice

authors： Remuzzi G,Ruggenenti P

更新日期：1998-04-01 00:00:00

abstract：:We simultaneously determined 3H-thymidine incorporation, DNA content, and insulin biosynthesis in adult and fetal rat pancreatic islets. 3H-thymidine incorporation was measured after tissue solubilization. DNA was measured fluorometrically. Insulin biosynthesis was determined through 3H-leucine incorporation after imm...

journal_title：Diabetes research and clinical practice

authors： Sieradzki J,Chatterjee AK,Fleck E,Schatz H

更新日期：1988-07-13 00:00:00

abstract：:Analyses of direct effects of smoking on peripheral arteries were done using thermography, blood fluorometry and echography on 97 habitual smoker-diabetics without triopathy. There were found to be four types of thermographic changes following smoking, which varied according to the degree of atherosclerosis of the art...

journal_title：Diabetes research and clinical practice

authors： Fushimi H,Kubo M,Inoue T,Yamada Y,Matsuyama Y,Kameyama M

更新日期：1998-10-01 00:00:00

abstract：:The insulin sensitivity of intermediary metabolism was studied in 8 non-obese men with well-controlled diet-treated non-insulin dependent diabetes (NIDDM) using a low dose incremental insulin infusion (basal, 0.005 and 0.01 U/kg h-1). Results were compared to 8 healthy male control subjects matched (NIDDM vs. controls...

journal_title：Diabetes research and clinical practice

authors： Singh BM,Krentz AJ,Nattrass M

更新日期：1993-04-01 00:00:00

abstract：:There are scant data from African populations on the association between beta-cell function and response to treatment with oral hypoglycaemic agents in Type 2 diabetes mellitus (T2DM). Fasting plasma C-peptide (FCP) and glucagon-stimulated C-peptide (GSCP) levels were measured in 116 Nigerians with T2DM at a universit...

journal_title：Diabetes research and clinical practice

authors： Oli JM,Adeyemo AA,Okafor GO,Ofoegbu EN,Onyenekwe B,Chukwuka CJ,Chen G,Chen Y,Doumatey AP,Aje TO,Rotimi CN

更新日期：2005-08-01 00:00:00

abstract：:To elucidate the relationship between carnitine metabolism and plasma ketone body concentrations in moderately obese patients with mild glucose intolerance, the ketone body and carnitine levels in the basal state were determined in 72 obese patients: 20 with normal glucose tolerance (NGT), 29 with impaired glucose tol...

journal_title：Diabetes research and clinical practice

authors： Inokuchi T,Imamura K,Nomura K,Nomoto K,Isogai S

更新日期：1995-10-01 00:00:00

abstract：:We retrospectively examined the frequency of bladder cancer in Japanese patients with type 2 diabetes in relation to use of pioglitazone. Among a total of 663 patients identified to be taking pioglitazone, 9 had bladder cancer (1.36%). Overall the hazard ratio of 1.75 [95% CI: 0.89-3.45] for pioglitazone for bladder c...

journal_title：Diabetes research and clinical practice

authors： Fujimoto K,Hamamoto Y,Honjo S,Kawasaki Y,Mori K,Tatsuoka H,Matsuoka A,Wada Y,Ikeda H,Fujikawa J,Koshiyama H

更新日期：2013-02-01 00:00:00

abstract：:Xenotransplantation of pig islets under the kidney capsule (KC) of diabetic rats was performed. Natural preformed ACI rat anti-pig leukocytotoxicity, leukoagglutination and hemagglutination antibody titers ranged from Neat-1: 16, 1:8-1:32 and 1:128-1:256, respectively (n = 14). Normal ACI sera were non-toxic to pig is...

journal_title：Diabetes research and clinical practice

authors： Tze WJ,Tai J,Cheung SS

更新日期：1992-03-01 00:00:00

abstract：AIMS:The objective of the present analysis was to evaluate and quantify the risk for gestational diabetes mellitus (GDM) according to maternal age. METHODS:Three electronic databases were searched for publications from inception to July 2018. Odds ratio (OR) and 95% confidence interval (95% CI) were calculated. A dose...

journal_title：Diabetes research and clinical practice

authors： Li Y,Ren X,He L,Li J,Zhang S,Chen W

更新日期：2020-04-01 00:00:00

abstract：:Hyperglycemia in patients admitted to hospital with myocardial infarction has been associated with adverse outcomes. However, with the improvements in survival seen in the reperfusion era, the glycometabolic state of patients presenting with acute myocardial infarction (AMI) is often given a low priority. The aim of t...

journal_title：Diabetes research and clinical practice

authors： Wong VW,Ross DL,Park K,Boyages SC,Cheung NW

更新日期：2004-05-01 00:00:00