Possible link of pioglitazone with bladder cancer in Japanese patients with type 2 diabetes.

Abstract:

:We retrospectively examined the frequency of bladder cancer in Japanese patients with type 2 diabetes in relation to use of pioglitazone. Among a total of 663 patients identified to be taking pioglitazone, 9 had bladder cancer (1.36%). Overall the hazard ratio of 1.75 [95% CI: 0.89-3.45] for pioglitazone for bladder cancer was not significant. However the prevalence of bladder cancer was 2.10% in patients taking pioglitazone for less than 24 months which was significant increased (HR 2.73 [95% CI: 1.11-6.72]).

authors

Fujimoto K,Hamamoto Y,Honjo S,Kawasaki Y,Mori K,Tatsuoka H,Matsuoka A,Wada Y,Ikeda H,Fujikawa J,Koshiyama H

doi

10.1016/j.diabres.2012.11.013

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

e21-3

issue

2

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(12)00475-5

journal_volume

99

pub_type

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