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Waist circumference cut-off points for the diagnosis of metabolic syndrome in Iranian adults.

Abstract：

AIMS:Central obesity, a prominent feature of metabolic syndrome (MetS), is commonly assessed by gender- and ethnicity-specific waist circumference (WC) cut-off values. Since 2006, the recommended WC cut-offs by the International Diabetes Federation (IDF) for Europeans are used in Iran because of limited data availability. The purpose of this study was to determine optimal cut-off points for the diagnosis of MetS in Iran. METHODS:A total of 2752 adults (1046 men) were studied. Subjects with two or more of the following risk factors from the IDF criteria were considered to have multiple risk factors: hyperglycemia (FBG>/=100mg/dL or diagnosed diabetes), high blood pressure (SBP>/=130mmHg, DBP>/=85mmHg, or using antihypertensive drugs), low HDL (<50mg/dL for females and <40mg/dL for males), and high TG (>150mg/dL). RESULTS:The WC cut-off yielding maximum sensitivity plus specificity for predicting the presence of multiple risk factors was 91.5cm in men and 85.5cm in women. Sensitivity and specificity were 77% (86%) and 58% (50%) in men (women), respectively. MetS prevalence was estimated to be approximately 27% in Tehran. CONCLUSIONS:WC cut-offs recommended by the IDF are not appropriate for use in Iran.

journal_name

Diabetes Res Clin Pract

journal_title

Diabetes research and clinical practice

authors

Esteghamati A,Ashraf H,Rashidi A,Meysamie A

doi

10.1016/j.diabres.2008.07.009

subject

Has Abstract

pub_date

2008-10-01 00:00:00

pages

104-7

issue

1

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(08)00315-X

journal_volume

82

pub_type

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