Insulin inhibits glucagon-induced glycogenolysis normally in perivenous hepatocytes of Wistar fatty rats.

abstract：INTRODUCTION:The COVID-19 pandemic has forced governments to take exceptional measures to minimize its spread, imposing lockdown policies. The aim of this study was to evaluate the impact of lockdown on type 1 diabetes (T1D) glycemic control. MATERIAL AND METHODS:People with T1D using flash glucose monitoring were inc...

journal_title：Diabetes research and clinical practice

authors： Fernández E,Cortazar A,Bellido V

更新日期：2020-08-01 00:00:00

abstract：:Insulin antibodies (IAA) can be detected in the serum of the majority of newly diagnosed IDDM patients prior to insulin therapy. In first degree relatives of IDDM patients, IAA are associated with an increased risk of development of IDDM. However, the disease specificity of IAA, detected by radiobinding assays, has no...

journal_title：Diabetes research and clinical practice

authors： Harrop M,Caudwell J,Stojanovski C,Colman PG

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:Studies of diabetes in migrant populations have shown a higher prevalence compared to their respective countries of origin and to people natively born in the host country, but there is little population-based data on diabetes incidence and mortality in migrant populations. The aim of the current study was (1)...

journal_title：Diabetes research and clinical practice

authors： Andersen GS,Kamper-Jørgensen Z,Carstensen B,Norredam M,Bygbjerg IC,Jørgensen ME

更新日期：2016-12-01 00:00:00

abstract：:We examined cross-sectional associations of sex hormone binding globulin (SHBG) with glucose among women recent GDM (n=55). SHBG was associated with fasting glucose levels before and after adjustment for covariates (p=0.015), but not with 2-h glucose. We conclude SHBG should be explored in prospective studies in GDM w...

journal_title：Diabetes research and clinical practice

authors： Kim C,Sen A,Osborne E,Lee JM,Richardson CR

更新日期：2011-09-01 00:00:00

abstract：:The current study evaluates the indices of glucose control for diabetics (i.e., glycated albumin (GA), hemoglobin A1c (HbA1c), plasma glucose (PG) and immuno-reactive insulin (IRI)) in non-diabetic children from a population-based cohort, and compares those values according to the presence of obesity to examine any di...

journal_title：Diabetes research and clinical practice

authors： Nishimura R,Kanda A,Sano H,Matsudaira T,Miyashita Y,Morimoto A,Shirasawa T,Kawaguchi T,Tajima N

更新日期：2006-03-01 00:00:00

abstract：AIMS:The current study sought to identify patient-level factors related to health care use among White and minority men and women with diabetes. METHODS:A sample of 447 of non-pregnant individuals with diabetes, ages 18-64, was drawn from the 2015-2016 National Health and Nutrition Examination Surveys dataset. Poisson...

journal_title：Diabetes research and clinical practice

authors： Wong JJ,Hood KK,Breland JY

更新日期：2019-04-01 00:00:00

abstract：:Well-organized medical insurance systems cover all medical fees for diabetes mellitus, and diabetics can visit doctors quite freely in Japan. Also insulin therapy by self-injection became legal and covered by health insurance after 1981 in this country. Despite such good conditions for the patients, there are some pro...

journal_title：Diabetes research and clinical practice

authors： Hirata Y

更新日期：1994-10-01 00:00:00

abstract：:Fifty-nine women with recent gestational diabetes participated in a randomized controlled trial to assess the feasibility and efficacy of a pragmatic diabetes risk reduction intervention. Intervention participants achieved improvements in energy, total and saturated fats, and carbohydrate intake, but no change in phys...

journal_title：Diabetes research and clinical practice

authors： Smith BJ,Cinnadaio N,Cheung NW,Bauman A,Tapsell LC,van der Ploeg HP

更新日期：2014-12-01 00:00:00

abstract：AIMS:We evaluated whether glucose fluctuation (GF) causes vascular endothelial injury and affects glucometabolic factors during lengthy oral glucose tolerance test (OGTT). METHODS:We enrolled consecutive 116 patients with coronary artery disease (CAD) who were performed coronary angiography and 4-h OGTT. Blood samples...

journal_title：Diabetes research and clinical practice

authors： Murata M,Adachi H,Oshima S,Kurabayashi M

更新日期：2017-09-01 00:00:00

abstract：:A 15 year follow-up study of diabetic patients was performed in Osaka, Japan. The subjects studied were 1939 patients with non-insulin dependent diabetes mellitus (NIDDM), of whom 1000 (51.5%) were alive, 880 (45.4%) had died and 59 (3.0%) were untraceable at the end of 1993. The mortality rate per 1000 person-years o...

journal_title：Diabetes research and clinical practice

authors： Sasaki A,Uehara M,Horiuchi N,Hasegawa K,Shimizu T

更新日期：1996-09-01 00:00:00

abstract：:A transient rise in hepatic glucose production (HGP) after an oral glucosa load has been reported in some insulin-resistant states such as in obese fa/fa Zucker rats. The aim of this study was to determine whether this rise in HGP also occurs in subjects with established non-insulin-dependent diabetes mellitus (NIDDM)...

journal_title：Diabetes research and clinical practice

authors： Thorburn A,Litchfield A,Fabris S,Proietto J

更新日期：1995-05-01 00:00:00

abstract：:Vascular complications, as a consequence of atherosclerosis, are the main causes of morbidity and mortality in diabetes. Low density lipoprotein (LDL) oxidation is accepted as a relevant pathogenic mechanism in atherogenesis. The aim of this work was to study the relationship between lipid peroxidation (LPO) and metab...

journal_title：Diabetes research and clinical practice

authors： Freitas JP,Filipe PM,Rodrigo FG

更新日期：1997-05-01 00:00:00

abstract：AIMS:To evaluate the clinical factors affecting daily and day-to-day glucose variability by using continuous glucose monitoring. METHODS:We performed a cross-sectional analysis of patients with type 2 diabetes mellitus (T2DM) who underwent a glucagon stimulation test (GST) with 72 h of continuous glucose monitoring. D...

journal_title：Diabetes research and clinical practice

authors： Ohara M,Hiromura M,Nagaike H,Kohata Y,Fujikawa T,Goto S,Sato N,Kushima H,Terasaki M,Yamamoto T,Mori Y,Hayashi T,Fukui T,Yamagishi SI,Hirano T

更新日期：2019-12-01 00:00:00

abstract：:The current study investigated whether Du-zhong (Eucommia ulmoides Oliv.) leaves could improve the hyperglycemia in streptozotocin (STZ)-induced diabetic rats. Male Sprague-Dawley rats were divided into a non-diabetic group (NDM), diabetic group (DM), diabetic group supplemented with powdered Du-zhong leaves (DM-PDZ) ...

journal_title：Diabetes research and clinical practice

authors： Lee MK,Kim MJ,Cho SY,Park SA,Park KK,Jung UJ,Park HM,Choi MS

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:A growing number of people with type 1 diabetes (T1DM) are identified with features of metabolic syndrome (MS) known as "double diabetes", but epidemiologic data on the prevalence of MS in T1DM and its comorbidities are still lacking. Aim of this cross sectional study is to better estimate the prevalence of ...

journal_title：Diabetes research and clinical practice

authors： Merger SR,Kerner W,Stadler M,Zeyfang A,Jehle P,Müller-Korbsch M,Holl RW,DPV Initiative.,German BMBF Competence Network Diabetes mellitus.

更新日期：2016-09-01 00:00:00

abstract：:This systematic review with meta-analysis examined whether lifestyle modification (diet and/or exercise) is effective for glycemic control in adults with type 2 diabetes in Southeast Asia. Results showed that lifestyle modification is effective in the short term (3months), but not over the longer term (6months) in thi...

journal_title：Diabetes research and clinical practice

authors： Htoo ZW,Hsu WW,Rosenkranz R

更新日期：2016-12-01 00:00:00

abstract：AIMS:To evaluate the natural history of gastric emptying in type 2 diabetes. METHODS:12 patients with type 2 diabetes (7 female; age 65.6 ± 1.2 years; duration of known diabetes 22.9 ± 1.5 years) were invited to return for repeat measurements of gastric emptying using the same dual-labelled solid and liquid meal, a me...

journal_title：Diabetes research and clinical practice

authors： Watson LE,Phillips LK,Wu T,Bound MJ,Jones KL,Horowitz M,Rayner CK

更新日期：2019-08-01 00:00:00

abstract：AIMS:To develop a risk "engine" or calculator, integrating the risks of hyperglycemia, maternal BMI and other basic demographic data commonly available at the time of the pregnancy oral glucose tolerance test (OGTT), to predict an individual's absolute risk of specific adverse pregnancy outcomes. METHODS:Data from the...

journal_title：Diabetes research and clinical practice

authors： McIntyre HD,Gibbons KS,Lowe J,Oats JJN

更新日期：2018-05-01 00:00:00

abstract：:The lesions of diabetic nephropathy have been considered to be irreversible. Pancreas transplantation is the only available treatment able to restore long-term normoglycemia without exposing the patients to the risks of severe hypoglycemia; thus allowing testing the effects of very long-term euglycemia in preventing, ...

journal_title：Diabetes research and clinical practice

authors： Fioretto P,Barzon I,Mauer M

更新日期：2014-06-01 00:00:00

abstract：:Our aim was to see the levels of lipoprotein (a) (Lp (a)) in patients with gangrenous or non-gangrenous diabetic foot lesions. Twenty-two patients with gangrenous foot lesions, 11 with non-gangrenous foot lesions and 10 healthy subjects were included in the study. All the patients had similar glycemic control and dura...

journal_title：Diabetes research and clinical practice

authors： Unlühizarci K,Muhtaroğlu S,Kabak S,Bayram F,Keleştimur F

更新日期：2006-02-01 00:00:00

abstract：AIMS:We examined whether 0.9 mg/day liraglutide plus basal insulin (Lira-basal) is superior to basal-bolus insulin therapy (BBIT) for type 2 diabetes (T2DM) without severe insulin deficiency as determined by glucagon stimulation. METHODS:Fifty patients receiving BBIT were enrolled in this 24-week, prospective, randomi...

journal_title：Diabetes research and clinical practice

authors： Yamamoto S,Hayashi T,Ohara M,Goto S,Sato J,Nagaike H,Fukase A,Sato N,Hiromura M,Tomoyasu M,Nakanishi N,Lee S,Osamura A,Yamamoto T,Fukui T,Hirano T

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:To evaluate the efficacy of continuous glucose monitoring system (CGMS) to detect postprandial hyperglycemia and unrecognized hypoglycemia in type 1 diabetes mellitus (DM1) patients. METHODS:We studied 46 patients (43.4%M/56.6%F), average age of 25.9+/-12.8 years, submitted to 72 h CGMS. It were analyzed: c...

journal_title：Diabetes research and clinical practice

authors： Maia FF,Araújo LR

更新日期：2007-01-01 00:00:00

abstract：:We report that mitochondrial DNA (MtDNA) copy numbers are increased in peripheral blood of patients with diabetic nephropathy (DN). Using qPCR for quantitation, we found a 2-4-fold significant increase (p<0.05) in the mean MtDNA values in DN patients vs. healthy controls and diabetics without nephropathy. Increased Mt...

journal_title：Diabetes research and clinical practice

authors： Malik AN,Shahni R,Iqbal MM

更新日期：2009-11-01 00:00:00

abstract：:Whether an OGTT reproducibly detects either type 2 diabetes (T2D) or prediabetes in Africans in unknown. Therefore, 131 Africans had two OGTT. Diagnostic reproducibility for T2D was excellent (κ = 0.84), but only moderate for prediabetes (κ = 0.51). A single OGTT positive for T2D may be sufficient to guide clinical ca...

journal_title：Diabetes research and clinical practice

authors： Jagannathan R,DuBose CW,Mabundo LS,Chung ST,Ha J,Sherman A,Bergman M,Sumner AE

更新日期：2020-12-01 00:00:00

abstract：:Recent clinical and experimental studies have suggested that diabetic patients may develop myocardial dysfunction in the absence of coronary heart disease and hypertension. In this study, the correlation between histopathological changes and myocardial dysfunction was studied in experimental diabetic rat hearts. Male ...

journal_title：Diabetes research and clinical practice

authors： Kita Y,Shimizu M,Sugihara N,Shimizu K,Yoshio H,Shibayama S,Takeda R

更新日期：1991-03-01 00:00:00

abstract：:The glycemic response following ingestion of carbohydrate in various forms is different. The factors involved are not fully elucidated. In this study the glycemic and insulin responses to 50 g of carbohydrate in the form of white bread (WB), semolina bread (SB), white spaghetti (WS) and wholemeal spaghetti (BS) were c...

journal_title：Diabetes research and clinical practice

authors： d'Emden MC,Marwick TH,Dreghorn J,Howlett VL,Cameron DP

更新日期：1987-07-01 00:00:00

abstract：:A low-carbohydrate/high-fat evening meal impaired the glucose tolerance of healthy subjects to almost the same extent as the impairment caused by overnight fasting. This suggests that the decreased component (carbohydrate) is more relevant than the increased component (fat) to the impairment of glucose tolerance by a ...

journal_title：Diabetes research and clinical practice

authors： Wang Y,Kaneko T,Wang PY,Sato A

更新日期：2002-01-01 00:00:00

abstract：INTRODUCTION:The literature on health aspects of Ramadan fasting is widely spread in many journals making it not readily available to those interested in the subject. MATERIALS AND METHODS:A narrative, non-systematic review of the international literature from two major online databases (viz. Scopus, PubMed) in one ye...

journal_title：Diabetes research and clinical practice

authors： Beshyah SA,Ali KF,Hafidh K,Hajjaji IM

更新日期：2020-12-11 00:00:00

abstract：AIM:To examine patient formation of implementation plans, a volitional strategy, and its influence on self-monitoring of blood glucose (SMBG). METHODS:A randomized experimental-control design over a 2-week time period was used. The study population was diabetes patients with HbA1c >7% and requiring insulin therapy. Pa...

journal_title：Diabetes research and clinical practice

authors： Nadkarni A,Kucukarslan SN,Bagozzi RP,Yates JF,Erickson SR

更新日期：2010-07-01 00:00:00

abstract：:Self-monitoring of blood glucose (SMBG) has been considered one major breakthrough in diabetes therapy because, for the first time, patients were able to determine their blood glucose levels during daily life. It seems obvious that this must be of advantage to disease management and clinical outcome, but it has become...

journal_title：Diabetes research and clinical practice

authors： Kolb H,Kempf K,Martin S,Stumvoll M,Landgraf R

更新日期：2010-02-01 00:00:00