Abstract:
:The current study evaluates the indices of glucose control for diabetics (i.e., glycated albumin (GA), hemoglobin A1c (HbA1c), plasma glucose (PG) and immuno-reactive insulin (IRI)) in non-diabetic children from a population-based cohort, and compares those values according to the presence of obesity to examine any differences in these indices. GA, HbA1c, casual PG and casual IRI in obese children (n = 209) were compared to those of non-obese children (n = 1060) in Ina town, Saitama Prefecture, in 2002-2003. In obese children, the levels of HbA1c, PG and IRI were statistically higher when compared to those of non-obese children. In contrast, the median and intra-quartile range (IQR) of GA of obese children (13.6%: 12.6-14.7) was statistically lower when compared to that of non-obese children (14.3%: 13.5-15.4, p < 0.001). The low GA (%) in obese children is mainly due to the low absolute value of GA (g/dl) rather than a higher albumin value (g/dl). This is the first report to reveal that GA levels are low in obese, non-diabetic children. Additional data collection and an experimental approach are necessary to reveal the reasons behind lower GA levels in obese children.
journal_name
Diabetes Res Clin Practjournal_title
Diabetes research and clinical practiceauthors
Nishimura R,Kanda A,Sano H,Matsudaira T,Miyashita Y,Morimoto A,Shirasawa T,Kawaguchi T,Tajima Ndoi
10.1016/j.diabres.2005.07.008subject
Has Abstractpub_date
2006-03-01 00:00:00pages
334-8issue
3eissn
0168-8227issn
1872-8227pii
S0168-8227(05)00302-5journal_volume
71pub_type
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