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Association of automated carotid IMT measurement and HbA1c in Japanese patients with coronary artery disease.

Abstract：

AIMS:The purpose of this study was to evaluate whether carotid IMT (cIMT) identified using automated software is associated with HbA1c in Japanese patients with coronary artery disease. METHODS:370 consecutive patients (males 218; median age 69 years ± 11) who underwent carotid-US and first coronary angiography were prospectively analyzed. After ultrasonographic examinations were performed, the plaque score (PS) was calculated and automated IMT analysis was obtained with a dedicated algorithm. Pearson correlation analysis was performed to calculate the association between automated IMT, PS and HbA1c. RESULTS:The mean value of cIMT was 1.00 ± 0.47 mm for the right carotid and 1.04 ± 0.49 mm for the left carotid; the average bilateral value was 1.02 ± 0.43 mm. No significant difference of cIMT was detected between men and women. We found a direct correlation between cIMT values and HbA1c (p=0.0007) whereas the plaque score did not correlate with the HbA1c values (p>0.05) CONCLUSION: The results of our study confirm that automated cIMT values and levels of HbA1c in Japanese patients with coronary artery disease are correlated whereas the plaque score does not show a statistically significant correlation.

journal_name

Diabetes Res Clin Pract

journal_title

Diabetes research and clinical practice

authors

Saba L,Ikeda N,Deidda M,Araki T,Molinari F,Meiburger KM,Acharya UR,Nagashima Y,Mercuro G,Nakano M,Nicolaides A,Suri JS,Fellow AIMBE.

doi

10.1016/j.diabres.2013.03.032

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

348-53

issue

3

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(13)00131-9

journal_volume

100

pub_type

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