Abstract:
BACKGROUND:Transmission of oncogenetic information (TOI) by probands to their families is of major importance to organize medical prevention in his family. Little is known about the difficulties that the proband faces when he tries to endorse his "duty to warn". METHODS:To characterize the barriers to TOI, a survey was performed, previously to the bioethic law of 2011, on a representative sample of 337 counselees seen in the last 10 years at the Centre Jean-Perrin Oncogenetics Department. A questionnaire comprising 97 items was prepared by experts and validated by a group of patients and health professionals. Nineteen Lickert-scale questions specially concerned TOI. RESULTS:Analysis found two dimensions, one of emotions and one concerning communication attitudes. Both dimensions were negatively correlated (r=-0.34, P<10(-7)): high emotional levels limited communication attitudes. The probands' history of cancer was the main factor impacting TOI. TOI was more difficult for cancer patients than for healthy counselees (P=0.025). Delay since consultation and type of cancer risk had no bearing on TOI. CONCLUSION:Cancer and its treatments seem to deeply affect patient's relatives and limit his capacity to involve his family into the oncogenetic inquiry. Measures are suggested to help ex-patients improve TOI.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Kwiatkowski F,Laquet C,Dessenne P,Bignon YJdoi
10.1016/j.bulcan.2014.09.001subject
Has Abstractpub_date
2015-02-01 00:00:00pages
162-73issue
2eissn
0007-4551issn
1769-6917pii
S0007-4551(14)00017-4journal_volume
102pub_type
杂志文章abstract::The high rate of recurrence after apparently complete surgery and/or complete clinical response to chemotherapy implies that most patients have undetected minimal residual disease. Novel techniques such as laparoscopic or laparotomic fluorescence may prove to be crucial in reassessing the definition of primary outcome...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2013.1730
更新日期:2013-04-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章,多中心研究
doi:
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journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1987-01-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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更新日期:1994-03-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
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更新日期:2006-04-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1998-06-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 信件
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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更新日期:1994-10-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1995-07-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2018.02.003
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journal_title:Bulletin du cancer
pub_type: 历史文章,杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 社论
doi:10.1016/S0007-4551(18)30384-9
更新日期:2018-12-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2016.03.003
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2009.0838
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
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pub_type: 杂志文章,评审
doi:
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2015.02.008
更新日期:2015-05-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2011.1366
更新日期:2011-06-09 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
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journal_title:Bulletin du cancer
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