[Histological and immunohistochemical diagnosis of bone marrow metastases of neuroblastomas].

Abstract:

:A retrospective, morphological and immunochemical study was performed on 60 bone marrow biopsies (BOM) and 12 tumor specimens surgically excised, from 9 patients with neuroblastoma (NB). Immunochemistry concerned "neuron-specific enolase" (NSE), chromogranin A (CGA) and synaptophysin (SP). The results of immunochemical stains and the study of reticulin network on the argentic stain were compared to the results of morphological evaluation on the routine stain. NSE, CGA and SP staining of tumor cells (part or all of them) was obtained from all surgical specimens. 17/75 BOM (20%) were discarded because of poor material. NB cells were observed in 24 BOM from 3 patients. Tumor cells formed large strands (1 patient) or nests (2 patients) associated with segregated cells. Diagnosis of metastatic BM involvement was negative or doubtful for 6 BOM (3 obtained at the same time, 2 patients), in which NB cells were clearly demonstrated by immunochemical staining of NSE and/or CGA. Reticulin and/or collagen myelofibrosis was present in 32/35 BOM from the 3 patients metastatic in bone marrow (BM+) even if NB cells could not be demonstrated in these samples.

journal_name

Bull Cancer

journal_title

Bulletin du cancer

authors

Boman F,Chastagner P,Floquet J,Sommelet D,Aymard B,Palau R,Kleinclaus I

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

943-51

issue

10

eissn

0007-4551

issn

1769-6917

journal_volume

78

pub_type

杂志文章
  • [Invasive cancer of the uterine cervix in young women: retrospective study of 236 cases].

    abstract::The study of cases treated between 1970 and 1984 at the Institut Curie, in women aged 40 years and under, was undertaken in order to determine the influence of age on prognosis. The incidence of these cases was stable throughout the 15 years study period as was the very high incidence of earlier cases: 84.5%. Earlier ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Fenton J,Chevret S,Asselain B,de La Rochefordière A,Mathieu G,Labib A,Durand JC,Salmon RJ

    更新日期:1990-01-01 00:00:00

  • [Combination of chemotherapy (vindesine, lomustine, cisplatin, cyclophosphamide) and thoracic radiotherapy in nonresectable non-small cell bronchial carcinoma: final results of a phase II clinical trial].

    abstract::Seventy-five patients with locally advanced non small cell lung carcinoma were entered in a phase II study combining chemotherapy (vindesine, lomustine, cisplatin and cyclophosphamide) and radical thoracic radiotherapy delivering a total dose of 60-65 Gy. Patients were regularly assessed by radiological and fiberoptic...

    journal_title:Bulletin du cancer

    pub_type: 临床试验,杂志文章

    doi:

    authors: Nasr E,Pellae-Cosset B,Arriagada R,Le Chevalier T,Baldeyrou P,Ruffie P,de Cremoux H,Martin M,Tarayre M

    更新日期:1992-01-01 00:00:00

  • Quality of care assessment for breast cancer: how to measure benefits of prevention and therapy in oncology.

    abstract::Over the last few years evaluation of quality of diagnostic and therapeutic care has become one of the most controversial and fastest growing fields of research in many areas of medicine. In this situation, oncology represents a model case as the conditions in which new therapeutic strategies are tested and implemente...

    journal_title:Bulletin du cancer

    pub_type: 临床试验,杂志文章

    doi:

    authors: Liberati A,Fossati R,Torri W

    更新日期:1987-01-01 00:00:00

  • [Hypoxia and angiogenesis].

    abstract::The presence of hypoxic regions within solid tumours is associated with a more malignant tumour phenotype and worse prognosis. To obtain a blood supply and protect against cellular damage and death, oxygen-deprived cells in tumours alter gene expression, resulting in resistance to therapy. Hypoxia is sensed at the cel...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Simon JM

    更新日期:2007-07-01 00:00:00

  • [Opioid switch and change of route of administration in cancer patients treated by morphine].

    abstract::This paper reviewed the 2002 guidelines established by the National Federation of Cancer Centres. A group of experts nominated by the 3 French Societies involved in the treatment of cancer pain (AFSOS, SFAP, SFETD), established new guidelines ratios for morphine switching and/or changing of route of administration, in...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,实务指引,评审

    doi:10.1016/j.bulcan.2018.06.011

    authors: Michenot N,Rostaing S,Baron L,Faure S,Jovenin N,Hubault P,Delorme T,Collin E,Filbet M,Chvetzoff G,Delorme C,Minello C,Magnet M,Ammar D,Krakowski I,Poulain P

    更新日期:2018-11-01 00:00:00

  • [Metastatic stomach cancer: Clinical trials in Asia and in Occident].

    abstract::Although cytotoxic chemotherapy is the main therapeutic option to treat gastric cancer in the metastatic setting, molecular targeted agents have recently been introduced in an effort to improve survival outcomes which in average do not exceed 1 year. Trastuzumab and ramucirumab, antibodies directed against HER2 and VE...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2018.07.012

    authors: Bui QL,Grazziotin-Soares D,Hasiniatsy RE,Trinh HS,Richard S,Lotz JP,Gligorov J,Khalil A

    更新日期:2018-10-01 00:00:00

  • [Cured after an intraocular tumor].

    abstract::We describe the psychological reactions after diagnosis and treatment of the malignant intraocular tumors: uveal melanoma and retinoblastoma. The chapter on uveal melanoma includes general consideration on the treatment of these tumors, the psychological effects on the patients, the professional and social problems, t...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Desjardins L,Delage M,Lumbroso L,Levy C,Doz F

    更新日期:2001-11-01 00:00:00

  • [Ovarian cancer in France. Epidemiological, clinical and histological status].

    abstract::With 2 436 deaths in 1979, ovarian cancer is relatively infrequent in France comprising but 5 per cent of female mortality from malignant disease. However, the rate of increase in mortality is considerable, 70 per cent between 1955 and 1979 or 2,9 per cent per year, greater than that for female bladder and breast canc...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Berlie J,Tournade MF,Chauvergne J,Bastien H

    更新日期:1983-01-01 00:00:00

  • [TRP calcium channel and breast cancer: expression, role and correlation with clinical parameters].

    abstract::Breast cancer (BC) has the highest incidence rate in women in industrialized countries. Statistically, it is estimated that one out of 10 women will develop BC during her life. Evidence is accumulating for the role of ion channels in the development of cancer. Most studied ion channels in BC are K(+) channels, which a...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2012.1595

    authors: Ouadid-Ahidouch H,Dhennin-Duthille I,Gautier M,Sevestre H,Ahidouch A

    更新日期:2012-06-01 00:00:00

  • [End of chemotherapy decision for metastatic breast cancer patients.].

    abstract::If chemotherapy beyond the third line often gives sum clinical benefits, it is sometimes prescribed only to avoid telling bad news to patients. Palliative chemotherapy can lead to symptom reduction and greater health related quality-of-live, but longer survival is unlikely. Physician's questioning about chemotherapy c...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2009.0895

    authors: Bouleuc C,Chvetzoff G

    更新日期:2009-09-01 00:00:00

  • [Recognition of occupational cancers: review of existing methods and perspectives].

    abstract::Occupational risk factors represent a significant part of cancer causes and are involved in all type of cancers. Nonetheless, the frequency of these cancers is largely under-estimated. Parallel to the epidemiological approach (collective), the concept of occupational cancer is often linked (at the individual level) to...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Vandentorren S,Salmi LR,Brochard P

    更新日期:2005-09-01 00:00:00

  • [Patients' information in percutaneous core breast biopsy].

    abstract::Information takes a large part of patient's perceptions of the procedure. If the information is adapted, patients tolerate the procedure well. We point out indications and explain the different types of procedure. For infraclinical masses, sonographically guided automated core needle biopsy removes samples. Sonographi...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Barreau B,Tastet S,Lakdja F,Henriquès C,Valentin F,Labat MJ,Dilhuydy MH

    更新日期:2005-03-01 00:00:00

  • [Hepatic transport of mitoxantrone in relation to multiple resistance].

    abstract::We have examined the effect of cyclosporin A on transport processes (uptake, efflux, binding) of mitoxantrone in isolated rat liver cells. Accumulation and binding of mitoxantrone was rapid with or without cyclosporin A. The initial uptake was linear over a wide concentration range (1 to 1000 microM). For the first 10...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Coloma F,Lacarelle B,Poitou P,Filleul A,Covo J,Catalin J

    更新日期:1994-05-01 00:00:00

  • Traitement focal et traitement systémique dans la prise en charge du cancer du rein métastatique : une question de complémentarité.

    abstract:FOCAL TREATMENT AND SYSTEMIC THERAPY IN METASTATIC KIDNEY CANCER:COMPLEMENTARY APPROACHES: To treat metastatic renal cell carcinoma, therapies used are with an oral intake, for the vast majority, and have many side effects that may compromise observance. Strategies of drug holiday have been studied and, in case of an i...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1016/S0007-4551(18)30376-X

    authors: Salabert L,Sionneau B,Cochin V,Ravaud A,Gross-Goupil M

    更新日期:2018-12-01 00:00:00

  • [Squamous cell anal carcinoma. What's next ?]

    abstract::Despite its status as a rare disease, the incidence of the squamous cell carcinoma of the anus (SCCA) is surging, especially in its metastatic form. In addition, the prognosis of initially localized diseases has not substantially changed since the 1970s with a recurrence rate of between 25-40 % after the chemoradiothe...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2020.12.001

    authors: Kim S,Spehner L,Cabel L,Bidard FC,Borg C

    更新日期:2021-01-01 00:00:00

  • [Current trends in lung cancer mortality in France].

    abstract::Lung cancer is the first cause of death from cancer in males in France. This cancer is responsible for 19,000 deaths in males and 3,000 deaths in females. We studied the geographical and temporal variations in lung cancer mortality in France. The average increase in mortality clearly decreased in males, changing from ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Rezvani A,Doyon F

    更新日期:1996-11-01 00:00:00

  • Image guided radiotherapy for prostate cancer.

    abstract::The purpose of external beam radiotherapy is to sterilize malignant tumours and at the same time to avoid complications by radiation injury to the surrounding healthy tissues. Modern radiation techniques in recent years have allowed to safely escalate the dose by approximately 10% for the treatment of prostate cancer,...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2008.0599

    authors: Soete G,Verellen D,Storme G

    更新日期:2008-03-01 00:00:00

  • [Conservative management of malignant and borderline ovarian tumor].

    abstract::Conservative management of at least a part of one ovary and the uterus, in order to preserve fertility-potential, could be propose in most of patients with nonepithelial and borderline ovarian tumor. This conservative management could be performed even in patients with borderline ovarian tumor associated with noninvas...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Morice P,Camatte S,Wickart-Poque F,Rouzier R,Pautier P,Pomel C,Lhommé C,Haie-Meder C,Duvillard P,Castaigne D

    更新日期:2002-12-01 00:00:00

  • [Radiation-induced sarcoma].

    abstract::Based upon the literature, we discuss epidemiological, histopathological, clinical and treatment aspects of postirradiation sarcomas. The risk of postirradiation sarcoma is very low and negligible in comparison with the beneficial effect of radiotherapy, and it should not be a major factor influencing treatment decisi...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Melhouf MM,Amrani N,Dubois JB

    更新日期:1997-09-01 00:00:00

  • [Analysis of the growth kinetics of autochthonous DMBA-induced tumors in mice of various ages and sex].

    abstract::In order to understand the kinetics of this experimental model, we studied the influence of age and sex on primary tumoral and pulmonary metastatic yields and on the growth kinetics parameters. Connective tissue tumors were induced by DMBA in male and female Swiss mice of various ages (pre and postpubertal, adult and ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Vrignaud P,Denechaud M

    更新日期:1985-01-01 00:00:00

  • [10-year retrospective analysis of the sequelae of loco-regional treatment of breast cancer].

    abstract::With a minimum follow-up period of 10 years, the incidence of sequelae after loco-regional treatment of 349 breast cancers remains low, being dominated by lymphoedema. Rare after treatment by irradiation alone, lymphoedema appears more frequently in patients treated by radio-surgical association, in spite of a moderat...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Calitchi E,Cheula JM,Otmezguine Y,Roucayrol AM,Mazeron JJ,Le Bourgeois JP,Pierquin B

    更新日期:1984-01-01 00:00:00

  • [Tamoxifen and endometrial adenocarcinoma].

    abstract::The authors report a case of endometrial carcinoma treated with tamoxifen introduced after normal initial uterine curettage. Based on recent experimental and clinical data, the importance of a gynecological follow-up in anti-estrogen therapy is emphasized. ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Rodier JF,Camus E,Janser JC,Renaud R,Rodier D

    更新日期:1990-01-01 00:00:00

  • [Breast cancer's impact on work life. Survey among women of the ELIPPSE cohort].

    abstract::Working people who are diagnosed with cancer must generally stop working, and returning to work after treatment is a very important issue for them. This article investigates the impact of cancer on professional trajectory among working women after a breast cancer diagnosis. We conducted in-depth interviews with 21 wom...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2012.1611

    authors: Gallardo L,Rey D,Peretti-Watel P

    更新日期:2012-07-01 00:00:00

  • [The frequency of cancer in France in year 2002, and trends since 1968].

    abstract::The estimated number of cancers diagnosed in 2002 is 150,000 in the male population and 120,000 in the female population and there were close to 88,000 cancer deaths among men and 59,000 cancer deaths among women in France. The most frequent cancer sites in the male population are prostate, lung, colon, intestine and ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Hill C,Doyon F

    更新日期:2006-01-01 00:00:00

  • [Carcinoembryonic antigen in carcinoma of the uterine cervix (author's transl)].

    abstract::The authors analyse 123 cases of carcinoma of the uterine cervix treated by radiotherapy, with CEA radio-immuno-assay performed before treatment then each time patients are seen in follow-up. The CEA level is positive in 35 per cent of the cases with a mean value of 21 per cent for stage I, 36 per cent for stage II an...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Bolla M,Vrousos C,Horiot JC,Bordes M,Le Dorze C

    更新日期:1979-01-01 00:00:00

  • [What future for circulating tumor DNA? Current data and prospects in colorectal, non-small cell lung and pancreatic cancers].

    abstract::Ten years after the discovery of the predictive value of KRAS status for anti-EGFR antibodies, other genes involved in oncogenesis and therapeutic responses were identified and are now systematically sought. Molecular diagnosis often requires invasive procedures, sometimes iatrogenic, and is limited by feasibility pro...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2015.10.017

    authors: Pietrasz D,Pécuchet N,Fabre E,Blons H,Chevalier L,Taly V,Laurent-Puig P,Bachet JB

    更新日期:2016-01-01 00:00:00

  • [Consultations in oncological supportive care mono-, multi-, ou interdisciplinary: What should we favour?].

    abstract::According to the point 7.6 and 7.7 of the Cancer Plan 2014, all cancer patients should have access to supportive care. Indeed, the supportive care consultation in oncology is an important tool for the symptom management of cancer patients at all times of treatment. This consultation can be mono-disciplinary or multi-d...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2015.04.019

    authors: Garnier SR,Pelletti C,Quenard C,Vallet F,Lemoine P,Guastella V,Rhondali W

    更新日期:2015-09-01 00:00:00

  • [Gemcitabine and breast cancer].

    abstract::Gemcitabine has demonstrated a good efficacy in number of tumor types. Thanks to its favourable toxicity profile, gemcitabine can be used in combination with a number of drugs. Single agent gemcitabine and gemcitabine-based combinations have been evaluated in metastatic breast cancer. Some of these combinations, such ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Besse B,Spano JP

    更新日期:2002-08-01 00:00:00

  • [Asbestos and malignant pleural mesothelioma: molecular, cellular and physiopathological aspects].

    abstract::Asbestos is known as mutagenic and carcinogenic for human and is responsible for many pulmonary diseases including asbestosis, bronchogenic carcinoma and malignant pleural mesothelioma. Occupational exposure to asbestos is involved in 70-80% of all malignant pleural mesothelioma. The later presents a growing challenge...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Mohr S,Keith G,Rihn B

    更新日期:2005-11-01 00:00:00

  • [First line chemotherapy of advanced epithelial ovarian cancer].

    abstract::The treatment of the advanced ovarian adenocarcinoma, most frequently stage at diagnostic, relies on association of surgery and chemotherapy. The current standard is the association carboplatine-paclitaxel. In spite of this treatment, relapses are frequent, and the prognosis thus remains very reserved. Presently the c...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2009.0987

    authors: Lhommé C,Even C,Morice P,Balleyguier C,Petrella M,Gouy S,Uzan C,Duvillard P,Pautier P

    更新日期:2009-12-01 00:00:00