Abstract:
INTRODUCTION:Adolescents and young adults (AYA, 15-25years old) with cancer are treated either in adult or pediatric units. Management of febrile neutropenia (FN) is different between these units. Monitoring rules and indications of hospitalization are often stricter in pediatrics. This study evaluates if these differences influence the occurrence of complications. METHODS:The medical records of AYA patients treated in our institution in the Euro-E-W-I-N-G99 protocol between 01/09/2000 and 31/05/2013 were retrospectively analyzed. We studied febrile neutropenias occurring after VIDE courses, during the induction period. RESULTS:Forty-four patients were included (18 from adult units, 26 from pediatrics). Median age at inclusion was 19.6. After 260 courses of VIDE, we observed a median of 2 FN per adult and 3 per pediatric patient (P=0.2). Hospitalization occurred in median 1.5 time per adult and 3 per pediatric patient (P=0.008). Median cumulated length of stay was 4.5days for adults versus 16 days for pediatric patients (P=0.008). There was no significant difference for survival, number of documented infections, transfusions, dose modifications, chemotherapy delay, need for intensive care, infection after post-induction surgery. CONCLUSION:AYA treated in adult services are less frequently hospitalized for FN with no difference in morbi-mortality. Homogeneous recommendations could be made for these patients, whatever the units they are treated in.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Penel-Page M,Normand C,Bertrand A,Levard A,Boyle H,Riberon C,Marec-Berard Pdoi
10.1016/j.bulcan.2015.08.001subject
Has Abstractpub_date
2015-11-01 00:00:00pages
915-22issue
11eissn
0007-4551issn
1769-6917pii
S0007-4551(15)00244-1journal_volume
102pub_type
杂志文章abstract::Adjuvant chemotherapy after apparently complete resection of gastrointestinal cancer may be theoretically justified by the high rate of local and metastatic recurrences. However, the results of controlled trials are generally disappointing, even if some of them have recently suggested some hope, chiefly for adjuvant t...
journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
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journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
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journal_title:Bulletin du cancer
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pub_type: 临床试验,杂志文章,评审
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2006-05-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/S0007-4551(20)30280-0
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-02-01 00:00:00
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journal_title:Bulletin du cancer
pub_type: 杂志文章
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journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
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journal_title:Bulletin du cancer
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