[Hospital teaching of oncology].

abstract：:Since premedication of patients with an H1 antihistamine is recommended before the start of the intravenous infusion of temsirolimus, temsirolimus is to be used with caution in cases where there is a history of hypersensitivity to this class of antihistamines, or medical contra-indication for treatment with antihistam...

journal_title：Bulletin du cancer

authors： Massard C,Patard JJ,Hermine O,Ravaud A

更新日期：2011-01-01 00:00:00

abstract：:This article, devoted specifically to gynaecological cancers and their impact on the sexual and marital lives, is a collaboration between the psychologists and onco-gynaecologist within a cancer center. In oncology, gynaecological cancers' treatments involve at the same time anatomical, physiological and functional mo...

journal_title：Bulletin du cancer

authors： Vanlerenberghe E,Sedda AL,Ait-Kaci F

更新日期：2015-05-01 00:00:00

abstract：:EXPRESSION III was designed to evaluate the information, needs and expectations of patients with ovarian cancer in different European countries. This abstract focuses on specific results from French OC patients. Two hundred and fifty-seven patients filled a 27-item questionnaire during a medical visit. Median age rang...

journal_title：Bulletin du cancer

authors： De Cock L,Kieffer A,Kurtz JE,Joly F,Weber B

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:French national guidelines lead us to increase the part of one-day breast cancer conservative surgery. Our objective was to check if we can enhance our outpatient part and to identify solutions to improve our practices. METHODS:From 01/01/2013 to 31/12/2014, we conducted a monocentric and retrospective re...

journal_title：Bulletin du cancer

authors： Gachon B,Nadeau C,Fritel X

更新日期：2015-12-01 00:00:00

abstract：:Pulmonary sarcomatoid carcinomas are a rare group of tumors accounting for about 1 % of non-small cell lung carcinoma (NSCLC). In 2004, World Health Organization classification united under this name all the carcinomas with sarcomatous or sarcomatous-like component with spindle cell or giant cell appearance. There are...

journal_title：Bulletin du cancer

authors： Vieira T,Duruisseaux M,Ruppert AM,Cadranel J,Antoine M,Wislez M

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:The French Patient Advocacy Group SOS Desmoid conducted a survey to measure the pain burden of desmoid tumor patients. MATERIAL AND METHODS:We used a structured questionnaire to measure the occurrence and consequences of pain. RESULTS:The pain occurrence was approximately 63%. In one-third of the cases, ...

journal_title：Bulletin du cancer

authors： Rigaux P,Lefebvre-Kuntz D,Penel N,“SOS Desmoïde”.

更新日期：2015-03-01 00:00:00

abstract：:CYP2D6 enzyme is implicated in the metabolism of drugs and nicotine. Genetic variability within CYP2D6, results in different CYP2D6 phenotypes. Inheritance of polymorphic CYP2D6 metabolizing enzyme is likely to be an important determinant of inter-individual variations in susceptibility to cancer. In this work, we hav...

journal_title：Bulletin du cancer

authors： Ouerhani S,Marrakchi R,Bouhaha R,Ben Slama MR,Sfaxi M,Ayed M,Chebil M,El Gaaied AB

更新日期：2008-02-01 00:00:00

abstract：:The objective of this study is to compare morbidity between 2 surgical procedures of axillary clearance: functional lymphadenectomy by classical dissection versus axillary dissection prepared by liposuction (Suzanne's procedure). Two hundred consecutive patients treated for breast cancer were included in a prospective...

journal_title：Bulletin du cancer

authors： Giard S,Laurent JC,Dron AM,Lefebvre D

更新日期：1997-03-01 00:00:00

abstract：:Based on the observation of a high incidence of breast cancer in the upper outer quadrant adjacent to the usual area of application of deodorants and/or antiperspirants, several scientific teams have advanced the hypothesis of a possible link between antiperspirants and breast cancer. The possibility of the involvemen...

journal_title：Bulletin du cancer

authors： Namer M,Luporsi E,Gligorov J,Lokiec F,Spielmann M

更新日期：2008-09-01 00:00:00

abstract：:Thyroid carcinoma on struma ovarii (TCSO) is a rare ovarian tumour, derivate from monodermic teratomas. It represents about 0.01% of overall ovarian tumours and 5 to 10% of struma ovarii. The diagnosis is histologic and retrospective after pelvic surgery; radiographic imaging being unspecific. Because of its rarity, t...

journal_title：Bulletin du cancer

authors： Lebreton C,Al Ghuzlan A,Floquet A,Kind M,Leboulleux S,Godbert Y

更新日期：2018-03-01 00:00:00

abstract：:We have treated in 1990 and 1991, 84 arteriovenous malformations (AVMs) by radiosurgery. Irradiation was realized by 5 to 7 arcs with 15 MV X rays circular minibeams of a GE-CGR Saturne 43 Linac diameter, at 100 cm 6 to 20 mm; the Betti arm chair and the Talairach frame. The prescribed peripheral dose containing the n...

journal_title：Bulletin du cancer

authors： Schlienger M,Merienne L,Lefkopoulos D

更新日期：1995-12-01 00:00:00

abstract：UNLABELLED:The legislative process of the surrogate appears to be unclear to health professionals and to patients and next of kin. To better adapt this process to the clinical practice our objective was here to document how the persons designated as surrogate perceived their role and how they described the difficulties...

journal_title：Bulletin du cancer

authors： Sarradon-Eck A,Capodano G,Bureau E,Julian-Reynier C

更新日期：2016-07-01 00:00:00

abstract：:Gemtuzumab ozogamicin (GO) is a humanized monoclonal antibody anti-CD33 conjugated with calicheamicin and was indicated for acute myeloid leukemia (AML) patients. It was initially approved in 2000 by FDA thank to promising results from a phase II trial including elderly relapsing AML patients. Numerous studies evaluat...

journal_title：Bulletin du cancer

authors： Brotelle T,Lemal R,Moluçon-Chabrot C,Bay JO,Delaunay J,Guièze R

更新日期：2014-02-01 00:00:00

abstract：:Newly synthesized dipyrido [4,3-b] [3,4-f] indole compounds have a structural similarity with the DNA intercalating agents ellipticines (pyrido-carbazoles). The procedure of synthesis of these compounds allows the addition of a lateral chain in position 1 of the nucleus. Comparison is made between different substituti...

journal_title：Bulletin du cancer

authors： Lidereau R,Chermann JC,Gruest J,Montagnier L,Ducrocq C,Rivalle C,Bisagni E

更新日期：1980-01-01 00:00:00

abstract：:Rapamycin (sirolimus) is a macrolide, related to cyclosporine with immunosuppressive properties and antiproliferative activity in various human tumor cells lines and tumor xenograft models. The cytosolic kinase mTOR which controls the initiation of the translation of messenger RNA is the main known target of rapamycin...

journal_title：Bulletin du cancer

authors： Alexandre J,Raymond E,Armand JP

更新日期：1999-10-01 00:00:00

abstract：:Seventy five human breast cancers were examined in order to search for the presence of thymidine kinase of the fetal-type (TK-F). The presence of TK-F was evidenced in all tumors. Its activity varied from one to another tumor, but it was evident that the increased TK activity observed in mammary cancers could exclusiv...

journal_title：Bulletin du cancer

authors： Javre JL,Hannouche N,Samperez S,Jouan P

更新日期：1986-01-01 00:00:00

abstract：:A nonfusing variant M4 of the L6 line of rat myoblasts was isolated. This subline was tumorigenic when inoculated into suckling rats. Comparative studies of cells growth in vitro, serum requirement, cell adhesiveness and capacity to form colonies in soft agar confirmed that M4 cells had undergone neoplastic transforma...

journal_title：Bulletin du cancer

authors： Hillion J,Leibovitch MP,Leibovitch SA,Harel J

更新日期：1982-01-01 00:00:00

abstract：INTRODUCTION:Since the last cancer plan 2014-2019, the assessment of the impact of the disease on caregivers became essential. The quality of caregiving represents an important part of the patient's quality of life. The main objective was to describe the evolution of caregiver's attachment style during the first three ...

journal_title：Bulletin du cancer

authors： Bonnet M,Vadam F,Belot RA,Quibel C,Pozet A,Nerich V

更新日期：2020-11-01 00:00:00

abstract：:Protein phosphorylation is a fundamental post-translational modification. It regulates a large number of critical cellular processes (differentiation, division, proliferation, apoptosis). Cell division is a process including a series of phases by which a parent cell divides into two daughter cells. The cells enter the...

journal_title：Bulletin du cancer

authors： Carassou P,Meijer L,Le Moulec S,Aoun J,Bengrine-Lefèvre L

更新日期：2012-02-01 00:00:00

abstract：:In the last ten years considerable progress has been made in small-cell lung carcinoma (SCLC) biology, along with the technical progress made in molecular biology. This progress now allows us to propose a model for the genesis and the development of this type of tumor. Tobacco, the principal causal factor plays a dual...

journal_title：Bulletin du cancer

authors： Levy R,Andrieu JM,Even P

更新日期：1992-01-01 00:00:00

abstract：:When cells are exposed to ionizing radiation, they initiate a complex response that includes the arrest of cell cycle progression in G1 and G2, apoptosis and DNA repair. DNA is an important subcellular target of ionizing radiation, but oxydative damage to plasma membrane lipids initiates signal transduction pathways t...

journal_title：Bulletin du cancer

authors： Teyssier F,Bay JO,Dionet C,Verrelle P

更新日期：1999-04-01 00:00:00

abstract：INTRODUCTION:The treatment of chronic myeloid leukemia (CML) has been revolutionized by the advent of tyrosine kinase inhibitors. The results of the IRIS trial demonstrated the efficacy and long-term safety profile of Imatinib. The objective of our work is to report the results at 15 years of treatment of CML in chroni...

journal_title：Bulletin du cancer

authors： Dakkoune M,Qachouh M,Zoukal S,Hassoune S,Khoubila N,Cherkaoui S,Lamchahab M,Rachid M,Madani A,Quessar A

更新日期：2020-09-01 00:00:00

abstract：:Cardiac neoplasms are a rare occurrence in clinical practice. The various frequencies of primary and secondary malignant tumors vary from report to report, approximately 1% in most autopsy series and 4% in cancer patient's autopsies. Cardiac malignancies account for less 1% of cardiac surgery and about for 0.1% of car...

journal_title：Bulletin du cancer

authors： Debourdeau P,Gligorov J,Teixeira L,Aletti M,Zammit C

更新日期：2004-11-01 00:00:00

abstract：:Occupational risk factors represent a significant part of cancer causes and are involved in all type of cancers. Nonetheless, the frequency of these cancers is largely under-estimated. Parallel to the epidemiological approach (collective), the concept of occupational cancer is often linked (at the individual level) to...

journal_title：Bulletin du cancer

authors： Vandentorren S,Salmi LR,Brochard P

更新日期：2005-09-01 00:00:00

abstract：:With over 70,000 patients treated worldwide, protontherapy has an evolution on their clinical applications and technological developments. The ballistic advantage of the Bragg peak gives the possibility of getting a high conformation of the dose distribution to the target volume. Protontherapy has accumulated a consid...

journal_title：Bulletin du cancer

authors： Mazal A,Habrand JL,Delacroix S,Datchary J,Dendale R,Desjardins L,Ferrand R,Malka V,Fourquet A

更新日期：2010-07-01 00:00:00

abstract：:As compared to conventional axillary dissection, the sentinel node technique is accompanied by reduced morbidity and shorter hospital stay. Based on available data, the use of this technique does not seem to yield higher rates of axillary recurrence. A combination of both radioisotope detection and blue dye increases ...

journal_title：Bulletin du cancer

authors： Hindié E,Groheux D,Espie M,Bourstyn E,Toubert ME,Sarandi F,de Roquancourt A,Giacchetti S,Cuvier C,Cahen-Doidy L,Teyton P,Misset JL,Maylin C,Moretti JL

更新日期：2009-06-01 00:00:00

abstract：:Through clearly identified molecular mechanisms, EGFR targeting leads to cell physiology modifications as cell proliferation, apoptosis and DNA repair. These mechanisms can explain the proper activity of EGFR targeting drugs but also represent a strong rational basis on which several experimental studies have been des...

journal_title：Bulletin du cancer

authors： Milano G,Magné N

更新日期：2003-11-01 00:00:00

abstract：:The natural history of breast diseases has changed overtime and successive therapeutic strategies have been adapted accordingly. Recently, biological findings on geno- and phenotypic characteristics of tumor cells offer new basis for the development of treatments that target homogenous and various subtypes of breast c...

journal_title：Bulletin du cancer

authors： Roché H

更新日期：2013-09-01 00:00:00

abstract：:Having to start chemotherapy during pregnancy remains a rare event. The decision to proceed this treatment relies on the drugs used, the time of exposure for the foetus and the gestational age at the time of exposure. As a matter of fact, the mutagenicity potential of the chosen medicine has to be known, and consequen...

journal_title：Bulletin du cancer

authors： Pautier P,Lhomme C,Morice P

更新日期：2002-09-01 00:00:00

abstract：:Urothelial tumors are very rare in children (to date, only about 150 cases have been reported worlwide). Only 20% occur before the age of ten. The aim of this study is to specify the clinicopathologic features of urothelial tumor in young patients, which require a slightly different approach to treatment. On the basis...

journal_title：Bulletin du cancer

authors： Grapin-Dagorno C,Peycelon M,Philippe-Chomette P,Berrebi D,El Ghoneimi A,Orbach D

更新日期：2017-02-01 00:00:00