Abstract:
:Small cell lung carcinoma is the most frequent cancer in man. In France, the geographic distribution is not homogenous and the frequency is time-dependent. The main risk factors are smoking and some professional exposures.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Flamant R,Hill C,Benhamou Ssubject
Has Abstractpub_date
1987-01-01 00:00:00pages
501-9issue
5eissn
0007-4551issn
1769-6917journal_volume
74pub_type
杂志文章abstract::The 4 year results of a prospective clinical trial on the treatment of operable breast cancer, comparing the effects of preoperative radiotherapy followed by surgery with those of surgery followed or not by postoperative radiotherapy are presented for patient groups of approximately 100 each. At 4 years 85 per cent su...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1977-01-01 00:00:00
abstract::Melanoma of the female genital tract is a rare location (less than 2% of melanomas all sites combined). These cancers have a very poor prognosis, due to the delay in diagnosis. Vulvar location is about 1% of melanomas then the vaginal location, uterine and ovarian. There is no consensus to date regarding their care, d...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2013.1881
更新日期:2014-01-01 00:00:00
abstract::Oxaliplatin in combination with 5-fluorouracil/leucovorin (LV5FU) improves the response rate and survival of patients with metastatic colorectal cancer. The objective of the Mosaic study was to evaluate the efficacy of this association in the adjuvant treatment of stage II and III colon cancer. This international stud...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00
abstract::Neoadjuvant chemoradiotherapy is considered at the present time as the standard treatment of most T3-4 rectal cancer. In France a combination of radiotherapy (45 Gy/5 weeks) with concurrent capecitabine (1,600 mg/m2) is the most popular protocol. Randomized trials try to optimize this approach using new cytotoxic drug...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2009.0838
更新日期:2009-03-01 00:00:00
abstract::In recent years, Internet has become an indispensable tool for all types of information. Its importance has increased in medicine and particularly in human malignancies. The data issued by the Internet are many and varied sources ranging from official websites to patient's blogs. HIV infection is an infection highly p...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2010.1160
更新日期:2010-10-01 00:00:00
abstract:FOCAL TREATMENT AND SYSTEMIC THERAPY IN METASTATIC KIDNEY CANCER:COMPLEMENTARY APPROACHES: To treat metastatic renal cell carcinoma, therapies used are with an oral intake, for the vast majority, and have many side effects that may compromise observance. Strategies of drug holiday have been studied and, in case of an i...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/S0007-4551(18)30376-X
更新日期:2018-12-01 00:00:00
abstract::Radiation induced lymphopenia is frequent and can be severe and durable. Although lymphocytes have long been known as highly radiosensitive cells, it is poorly characterized. Radiation-induced lymphopenia seems to affect lymphocyte subpopulations differently and seems to be influenced by radiation modalities. The dept...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2020.04.009
更新日期:2020-01-01 00:00:00
abstract::Advanced stage follicular lymphoma is incurable by conventional treatment. Important progress has been observed with the development of new therapies based on monoclonal antibodies and on the use of radioimmunotherapy (RIT) in the treatment of non-Hodgkin lymphomas (NHL). Rituximab in combination with chemotherapy in ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2007-09-01 00:00:00
abstract::Nasopharyngeal carcinoma (NPC) represents one of the most frequent epithelial tumours of the child in intermediate risk regions. In the Maghreb, it represents the first cancer of teenagers of 15-20 years old. The Epstein Barr virus (EBV) is the most important etiologic factor. Its role in the pathogeneses of NPC has b...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2010.1087
更新日期:2010-04-01 00:00:00
abstract::The anticancer drug technical commission (COTECH) of the Auvergne OMEDIT has set up a region-wide professional practice evaluation (PPE) with regards to antiemetic prescription practices in chemotherapy-induced nausea and vomiting (CINV), in order to evaluate their compliance with OMEDIT's guidelines. Are not included...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2016.03.009
更新日期:2016-07-01 00:00:00
abstract::Irinotecan (CPT11), a topoisomerase I inhibitor, is a new cytotoxic agent with a broad spectrum of clinical activity. Two main schedules have been studied and produce similar activity and side-effects: the "european" one--350 mg/m2 every 21 days-, and the "japanese-north american" one where CPT11 is given at a weekly ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1998-12-01 00:00:00
abstract::We report a case of renal cell carcinoma presenting with bilateral adrenal masses diagnosed by ultrasonography four years after nephrectomy. The histopathological examination of the trucut biopsy specimens obtained percutaneously by ultrasound guidance revealed bilateral adrenal mestastases of renal cell carcinoma. ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1994-02-01 00:00:00
abstract::Two operational subdivisions of hereditary colorectal cancer susceptibility are those with and those without premalignant adenomatous colonic polyp expression. In both of these subdivisions, reliable biomarkers of gene carriage would be of value in patient management as we have previously emphasized. Consideration mus...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Soft tissue sarcomas (STS) are a set of very heterogeneous tumors with numerous histological categories. The development of the molecular biology allowed identifying recurring molecular anomalies in certain subgroups of sarcomas, being able to represent diagnostic, prognosis and therapeutic tools. The molecular classi...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2014.12.005
更新日期:2015-01-01 00:00:00
abstract::Little is known about the late effects of damage to the gonads in children treated for cancer. This investigation requires a prolonged surveillance. Radiotherapy sterilizes the ovaries above a dose of about 500 rads in an adult. Therefore, to protect at least one ovary in partial irradiation of a child's abdomen in ma...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::In chemosensitive tumors, cancer chemotherapy is active as drug combinations. During the development of new anticancer drugs, preclinical experimental models may help to design drug combinations. Indeed, in vitro models are able to define drug interactions in terms of synergism, additivity or antagonism, while in vivo...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract::Angiopoietin-2 is a new member of the family of the ligands of Tek (Tie2), a transmembrane receptor with tyrosine kinase activity which is specifically expressed in endothelial cells during angiogenesis. Several lines of evidence indicate that angiopoietin-1 is involved in pericyte recruitment by endothelial cells and...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract::We have examined the effect of cyclosporin A on transport processes (uptake, efflux, binding) of mitoxantrone in isolated rat liver cells. Accumulation and binding of mitoxantrone was rapid with or without cyclosporin A. The initial uptake was linear over a wide concentration range (1 to 1000 microM). For the first 10...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::This study was designed to evaluate the efficiency of the association ondansetron-dexamethasone during successive courses in 22 chemotherapy-naive female patients receiving a chemotherapy regimen including cisplatin at a dose of 100 mg/m2. The antiemetic treatment consisted of dexamethasone 20 mg i.v. and ondansetron ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::Glioblastoma multiforme still remains, at present, the most frequent and deadly primary malignant glioma in adult. Despite safer and larger neurosurgical resections, patients almost always relapse very close or inside the tumor bed. Since more than 20 years, radiation therapy (RT) continue delivering the same dose of ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2005-04-01 00:00:00
abstract::Malnutrition is common in oncology. However, it is often detected too late and nutritional support is sub-optimal. The patient's opinion, although often sought in therapeutic decisions in oncology, does not appear to be frequently taken into account in dietetic management. In NutriCancer2012 study, we interviewed pati...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2017.09.014
更新日期:2017-11-01 00:00:00
abstract::Based upon the literature, we discuss epidemiological, histopathological, clinical and treatment aspects of postirradiation sarcomas. The risk of postirradiation sarcoma is very low and negligible in comparison with the beneficial effect of radiotherapy, and it should not be a major factor influencing treatment decisi...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1997-09-01 00:00:00
abstract::Angiogenin is one of the most potent inducers of neovascularization in experimental models in vivo. Angiogenin is normally present in plasma but overexpressed in cancer patients. The possible involvement of angiogenin in the development of cancer is suggested by its overexpression in patients with a variety of tumours...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-08-01 00:00:00
abstract::Oncolor, network in oncology in Lorraine, was born ten years ago, from a group of professionals in the field of oncology who worked closed together with regional administrative authorities. Oncolor was created with respect of equilibrium between the different regional partners avoiding struggle for power. Oncolor was ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::Despite great improvements in the outcome of patients with lymphoma, some may still relapse or present with primary refractory disease. In these situations, allogeneic haematopoietic cell transplantation (allo-HCT) is a potentially curative option, in particular in the case of relapse after autologous stem cell transp...
journal_title:Bulletin du cancer
pub_type: 共识发展会议,杂志文章,实务指引,评审
doi:10.1016/j.bulcan.2017.08.008
更新日期:2017-12-01 00:00:00
abstract::Breast cancer (BC) has the highest incidence rate in women in industrialized countries. Statistically, it is estimated that one out of 10 women will develop BC during her life. Evidence is accumulating for the role of ion channels in the development of cancer. Most studied ion channels in BC are K(+) channels, which a...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2012.1595
更新日期:2012-06-01 00:00:00
abstract::UPDATED 2016 RECOMMENDATIONS FOR THE CLINICAL PRACTICE OF NICE/SAINT-PAUL-DE-VENCE IN OVARIAN CANCER AND ADVANCED CERVICAL CANCER: Since the first edition of the 2012-2013 Clinical Practice Recommendations Nice-Saint-Paul for gynecological cancers, the management of ovarian cancer has become more complex with a better...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/S0007-4551(17)30156-X
更新日期:2017-05-01 00:00:00
abstract::465 patients with broncho-pulmonary malignant tumors have been autopsied. Small cell carcinoma was diagnosed in 22.5 per cent of these patients. The histo-cytological variants of these tumors (lymphocytoid, polygonal, fusiform and polymorphic) had the same general characteristics (age, sex, survival) and a similar cli...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Cerebral non Hodgkin's lymphomas (NHL) of immunocompetent patients are rare disease (1% of all NHL), but their incidence has been steadily increasing in the last 20 years. Most cerebral NHL are diffuse large cell NHL with a B phenotype. These tumors are most often localized in the central nervous system, the eye or me...
journal_title:Bulletin du cancer
pub_type: 杂志文章,meta分析
doi:
更新日期:1997-10-01 00:00:00
abstract::In the last ten years considerable progress has been made in small-cell lung carcinoma (SCLC) biology, along with the technical progress made in molecular biology. This progress now allows us to propose a model for the genesis and the development of this type of tumor. Tobacco, the principal causal factor plays a dual...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00