[The Stockholm preoperative radiotherapy of operable breast cancer. Preliminary report].

Abstract:

:The 4 year results of a prospective clinical trial on the treatment of operable breast cancer, comparing the effects of preoperative radiotherapy followed by surgery with those of surgery followed or not by postoperative radiotherapy are presented for patient groups of approximately 100 each. At 4 years 85 per cent survive after preoperative radiotherapy plus surgery, as against 77 per cent after surgery only and 81 per cent after surgery plus postoperative radiotherapy. These differences are not statistically significant. The incidence of local recurrence after radiotherapy was reduced to 1/4 of that seen after surgery only. The radiation could be shown to induce temporary damage in a number of immunological parameters. No correlation could be demonstrated between these findings and the clinical course of the disease.

journal_name

Bull Cancer

journal_title

Bulletin du cancer

authors

Wallgren A,de Schryver A,Wasserman J

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

627-31

issue

4

eissn

0007-4551

issn

1769-6917

journal_volume

64

pub_type

临床试验,杂志文章,随机对照试验
  • [Fibrinolysis of deep venous thrombosis on implantable perfusion devices. Apropos of a consecutive series of 57 cases of thrombosis and 32 cases of fibrinolysis].

    abstract::The main complication of totally implantable venous access devices is deep venous thrombosis on catheter. It may dramatically reduce the already limited venous capacity of patients undergoing chemotherapy and obturate catheters, causing pulmonary embolism or functional disorders. These thromboses usually involve veins...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Pucheu A,Dierhas M,Leduc B,Sillet-Bach I,Lefort S,Assaf W,Pucheu M

    更新日期:1996-04-01 00:00:00

  • [Safety of selective inhibitors of inducible cyclooxygenase-2 taken for a long period].

    abstract::The serious digestive side effects of the selective inhibitors the inducible cyclooxygenase-2 are reduced by 60% as compared to the nonselective non-steroidal anti-inflammatory drugs. The main risk factors associated with gastro-intestinal ulcers caused by the latter were found also with the selective inhibitors taken...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Lamarque D

    更新日期:2004-05-01 00:00:00

  • [Pre-therapeutic and evolutive characteristics of patients suffering from chronic myeloid leukemia, in Abidjan, Ivory Coast].

    abstract:INTRODUCTION:The diagnosis of chronic myeloid leukemia is based on the presence of translocation t(9,22). Additional cytogenetic abnormalities may exist at diagnosis and have prognostic value. The authors evaluated the relationship between these additional chromosomal abnormalities, clinical presentation, and therapeut...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1016/j.bulcan.2019.03.013

    authors: Silué DA,Kouakou B,Nanho CD,Kamara I,Djoko S,Sowhe T,Meité N,Ayemou R,Emeuraude N,Tolo A,Koffi G,Sanogo I

    更新日期:2019-06-01 00:00:00

  • [Endometrial cancer and tamoxifen. Discussion apropos of a series of cases].

    abstract::Tamoxifen is widely used nowadays in the management of breast cancer, having established its efficacy in this indication, especially for postmenopausal patients with ER-positive breast tumours. However, tamoxifen has recently been recognized as carcinogenic for the human endometrium, probably with an effect of duratio...

    journal_title:Bulletin du cancer

    pub_type: 临床试验,杂志文章,多中心研究,评审

    doi:

    authors: Sasco AJ,Ah-Song R,Gendre I,Zlatoff P,Bobin JY,Hallonet P,Leduc B

    更新日期:1997-01-01 00:00:00

  • [New challenge in head and neck oncology surgery: the transoral robotic surgery].

    abstract::Robotic assisted surgery is a new field of developing program for many specialties. As to head and neck oncology, the new procedure potentially offers alternatives to conventional surgery with decreased morbidity. The aim of this article is a description of the state of the art via a review of the literature. We empha...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2009.1022

    authors: Mallet Y,Moriniere S,Ceruse P,El Bedoui S

    更新日期:2010-01-01 00:00:00

  • [Recent data on the immunology of tumors. Mechanisms of escape of immunological control. Role of suppressor cells].

    abstract::Cells in spleens from tumor bearing animals were found to inhibit in vitro reactivity of lymphocytes to a variety of stimulants. These suppressor cells inhibited the stimulation of normal lymphocytes by mitogens : P.H.A.-Con A-L.P.S. They were adherent cells, bore immunoglobulins at their surface and did not bear the ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Lespinats G,Poupon MF

    更新日期:1976-04-01 00:00:00

  • [Adaptation and validation of a brief screening questionnaire of depressive disorders in patients with cancer: Q2i study].

    abstract:BACKGROUND:Depression is a sustainable state of deep sadness and abatement. It is frequently identified in patients with cancer and often undervalued by oncologists. The reduced PRIME-MD questionnaire is a questionnaire of 2 items validated in French. However, it has been neither translated nor validated in French. The...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1016/j.bulcan.2015.09.008

    authors: Barriere J,Mari V,Cherikh F,Largillier R,Ettaiche M,Schiappa R,Chamorey E,Ferrero JM,Gal J

    更新日期:2016-02-01 00:00:00

  • [Announcing cancer diagnosis: which communication difficulties from professional and from patient's side? Which possible improvements?].

    abstract::Announcing a cancer diagnosis, but also a relapse, a progression of the disease, or transition towards palliative care constitute particularly difficult communication issues for the patient as well as for the clinician, during the trajectory of care. The objectives of this article is to present the clinical stakes of ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2010.1197

    authors: Dolbeault S,Brédart A

    更新日期:2010-10-01 00:00:00

  • [Cell signalling and cancer].

    abstract::Cell signalling represents the network of cell communication pathways. Reception of a message by a cell results in the implementation of various direct and indirect actions, especially through the transcription of the genes required for carrying out the orders received. The signals exchanged by cells may concern proli...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2010.1199

    authors: Robert J

    更新日期:2010-11-01 00:00:00

  • ARLTS1, potential candidate gene in familial aggregation of hematological malignancies.

    abstract:INTRODUCTION:Genetic predisposition to familial hematological malignancies was previously described through several epidemiological analyses, but the genetic basis remains unclear. The tumor-suppressor ARLTS1 gene was previously described in sporadic hematological malignancies and familial cancer context. METHODS:In t...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1016/j.bulcan.2016.10.016

    authors: Hamadou WS,Besbes S,Mani R,Bourdon V,Ben Youssef Y,Achour B,Regaieg H,Eisinger F,Mari V,Gesta P,Dreyfus H,Bonadona V,Dugast C,Zattara H,Faivre L,Noguchi T,Khélif A,Sobol H,Soua Z

    更新日期:2017-02-01 00:00:00

  • [Locoregional recurrence of ORL cancer: the place of surgery].

    abstract::Surgery of locoregional failures is mainly represented by salvage surgery after radiotherapy. Due to progress of radiotherapy, especially modification of fractionation and association with chemotherapy, the problem of salvage surgery is nowadays emphasized. Despite the reduction of postoperative mortality and morbidit...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Julieron M,Temam S

    更新日期:2004-11-01 00:00:00

  • [Bleomycin is an antineoplastic agent capable of mimicking apoptosis].

    abstract::Bleomycin (BLM), a currently used anticancer drug, crosses the plasma membrane poorly. Electropermeabilization allows a defined number of BLM molecules to enter directly into the cell cytoplasm. Such a procedure has revealed that BLM is endowed with a very high intrinsic cytotoxicity. Here we show that when several mi...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Tounekti O,Belehradek J Jr,Mir LM

    更新日期:1994-12-01 00:00:00

  • [Tamoxifen and endometrial adenocarcinoma].

    abstract::The authors report a case of endometrial carcinoma treated with tamoxifen introduced after normal initial uterine curettage. Based on recent experimental and clinical data, the importance of a gynecological follow-up in anti-estrogen therapy is emphasized. ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Rodier JF,Camus E,Janser JC,Renaud R,Rodier D

    更新日期:1990-01-01 00:00:00

  • [Prerequisite for hematopoietic cellular therapy programs to set up chimeric antigen receptor T-cell therapy (CAR T-cells): Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].

    abstract::CAR T-cells are autologous or allogeneic human lymphocytes that are genetically engineered to express a chimeric antigen receptor targeting an antigen expressed on tumor cells such as CD19. CAR T-cells represent a new class of medicinal products, and belong to the broad category of Advanced Therapy Medicinal Products ...

    journal_title:Bulletin du cancer

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1016/j.bulcan.2017.10.017

    authors: Yakoub-Agha I,Ferrand C,Chalandon Y,Ballot C,Castilla Llorente C,Deschamps M,Gauthier J,Labalette M,Larghero J,Maheux C,Moreau AS,Varlet P,Pétillon MO,Pinturaud M,Rubio MT,Chabannon C

    更新日期:2017-12-01 00:00:00

  • [Presence of free retinol receptor (cRBP) and retinoic acid receptor (cRABP) in human skin tumors].

    abstract::The concentrations of cellular retinoic acid binding protein (cRABP) and free cellular retinol binding protein (cRBP) were determined by ultracentrifugation in sucrose gradient in the cytosol of 41 human skin tumours (14 melanomas, 19 basal cell carcinomas, 8 squamous cell carcinomas). cRBP was found respectively in 3...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Delarue JC,Avril MF,Prade M,Petit JY

    更新日期:1986-01-01 00:00:00

  • [Molecular biology of sarcoma and therapeutic choices].

    abstract::Soft tissue sarcomas (STS) are a set of very heterogeneous tumors with numerous histological categories. The development of the molecular biology allowed identifying recurring molecular anomalies in certain subgroups of sarcomas, being able to represent diagnostic, prognosis and therapeutic tools. The molecular classi...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2014.12.005

    authors: Dufresne A,Cassier P,Heudel P,Pissaloux D,Wang Q,Blay JY,Ray-Coquard I

    更新日期:2015-01-01 00:00:00

  • [Statistical study of a series of 672 cases of carcinoma of the uterine cervix. Results and complications according to age and modalities of treatment].

    abstract::The study bears on 672 infiltrating carcinomas of the cervix treated from 1977 until the end of 1991, by a radiosurgical combination (311 patients) or by exclusive irradiation (361 patients). The radiosurgical series includes mostly stages IB and II and patients under 50 years because of the therapeutic protocol. Most...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Pernot M,Hoffstetter S,Peiffert D,Carolus JM,Guillemin F,Verhaeghe JL,Marchal C,Luporsi E,Beckendorf V,Stines J

    更新日期:1995-07-01 00:00:00

  • [Patients and the Web].

    abstract::In recent years, Internet has become an indispensable tool for all types of information. Its importance has increased in medicine and particularly in human malignancies. The data issued by the Internet are many and varied sources ranging from official websites to patient's blogs. HIV infection is an infection highly p...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2010.1160

    authors: Cluzeau T,Mounier N

    更新日期:2010-10-01 00:00:00

  • [Towards an inventory of oncogenic mutations in cancer].

    abstract::The discovery of oncogenes and tumor suppressors has established the original concept of cancer development based on a cascade of spontaneously occurring somatic mutations. It is now well known that genomes of cancer cells are deeply rearranged and that these rearrangements have devastating consequences on their organ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2010.1200

    authors: Theillet C

    更新日期:2010-11-01 00:00:00

  • [Neoadjuvant approach for non-metastatic rectal cancer combining radiotherapy and chemotherapy. Biotargeted drugs].

    abstract::Neoadjuvant chemoradiotherapy is considered at the present time as the standard treatment of most T3-4 rectal cancer. In France a combination of radiotherapy (45 Gy/5 weeks) with concurrent capecitabine (1,600 mg/m2) is the most popular protocol. Randomized trials try to optimize this approach using new cytotoxic drug...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2009.0838

    authors: Gérard JP,Francois E,Deustch E,Rostom Y,Douar N,Benezery K,Milano G

    更新日期:2009-03-01 00:00:00

  • Cardiotoxicity of 5-fluorouracil in 1350 patients with no prior history of heart disease.

    abstract::To show the nature and magnitude of EKG anomalies subsequent to 5-fluorouracil (5FU) administration and determine whether the onset is dependent on a pre-existing cardiovascular pathological condition. 1,350 patients were treated by 5FU between 1995 and 2000. EKG were recorded in all patients before each administratio...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Tsibiribi P,Descotes J,Lombard-Bohas C,Barel C,Bui-Xuan B,Belkhiria M,Tabib A,Timour Q

    更新日期:2006-03-01 00:00:00

  • [Primary cerebral tumors in children. II: Topography and treatment].

    abstract::In part I of this article, we reviewed the general aspects of childhood brain tumors. In part II, we present the most common neoplasms and their treatment. The quality of the surgical resection appears to be of first importance in the prognosis. Progress in radiotherapy and chemotherapy have contributed to the improve...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Carrie C,Bouffet E,Brunat-Mentigny M,Philip T,Lacroze M

    更新日期:1989-01-01 00:00:00

  • [Rare cancers and new radiotherapy techniques].

    abstract::Rare cancers represent about a quarter of all cancers diagnosed in Europe, and their incidence is increasing. Meanwhile, scientific advances provide techniques, which become more and more sophisticated in the domain of radiotherapy. Treatment options for radiotherapy rare cancers are increasing, but are not yet evalua...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1016/j.bulcan.2014.12.001

    authors: Espenel S,Trone JC,Vallard A,Guy JB,Moriceau G,Méry B,Langrand-Escure J,Rivoirard R,de Laroche G,Chargari C,Magné N

    更新日期:2015-01-01 00:00:00

  • Detailed overview on rare malignant ovarian tumors.

    abstract::The group of rare malignant ovarian tumors includes the group of germ cell tumors, sex cords stromal ovarian tumors, small cell carcinoma, malignant Brenner tumors, rare epithelial tumors such as mucinous carcinoma, clear cell carcinoma, or low-grade serous carcinoma, as well as ovarian carcinosarcoma. Together they c...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2020.01.011

    authors: Aust S,Eberst L,Tredan O,Rousset-Jablonski C,Treilleux I,Méeus P,Chopin N,Beurrier F,Charreton A,Véronique D,Hallouz A,Coulon A,Ricoeur A,Mastier C,Bouhamama A,Racadot S,Devouassoux-Shisheboran M,Haddad V,Ray-Coquard

    更新日期:2020-03-01 00:00:00

  • [Concrete pain prevention measures regarding hospital internal transport in a cancer center].

    abstract::Iatrogenic pain is a common problem for cancer patients, including those due to hospital internal transport. An original prospective study conducted in 2006 allowed risk factor identification, and from 2007, a pluri-annual progress plan was implemented. Its actions were systematically evaluated and all phases of trans...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2013.1787

    authors: Nebbak JM,Vignozzi A,Bussy C,Charleux D,Laplanche A,Mathivon D,Di Palma M

    更新日期:2013-07-01 00:00:00

  • [Frequency of cancer at older ages].

    abstract::The dependency between the risk of death and age is analysed, and the contribution of cancer to the overall risk of death is evaluated as a function of age. The frequency of the different cancer sites is described in different age groups. Lastly cancer mortality trends are presented by age. The risk of death from canc...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2007.0531

    authors: Hill C,Doyon F

    更新日期:2008-05-28 00:00:00

  • [Angiogenesis targeting in renal carcinomas].

    abstract::Angiogenesis targeting with inhibitors of VEGF receptors is currently modifying in depth the treatment strategy of metastatic clear cell renal carcinoma. Although immunotherapy remains prescribed in selected patients with good prognosis, sunitinib and sorafenib are presently the most active agents in this malignancy. ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Pouessel D,Culine S

    更新日期:2007-01-01 00:00:00

  • [Methodological and ethical quality in phase III cancer trials: role of the cooperative group].

    abstract::Phase III clinical trials (CT) are carried out more and more often in a multicentric way, under the aegis of one or more cooperative groups (CG). The goal of this study was to analyze the influence of the GC on ethical quality (EQ) and methodological quality (MQ) in phase III cancer CT. EQ (Berdeu-score) and MQ (Jadad...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Tuech JJ,Pessaux P,Moutel G,Thoma V,Schraub S,Hervé C

    更新日期:2004-10-01 00:00:00

  • [Patients' information in percutaneous core breast biopsy].

    abstract::Information takes a large part of patient's perceptions of the procedure. If the information is adapted, patients tolerate the procedure well. We point out indications and explain the different types of procedure. For infraclinical masses, sonographically guided automated core needle biopsy removes samples. Sonographi...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Barreau B,Tastet S,Lakdja F,Henriquès C,Valentin F,Labat MJ,Dilhuydy MH

    更新日期:2005-03-01 00:00:00

  • [Chemoradiotherapy and anal canal cancer].

    abstract::Local control and sphincter preservation are the two challenges of anal canal cancer treatment. These tumors are radio- and chemo-sensitive and treatment moved from surgical approach, with abdominoperineal resection, to definitive radiation therapy with or without concurrent chemotherapy. Randomised trials proved the ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Ortholan C,François E,Gérard JP

    更新日期:2005-12-01 00:00:00