[Polymorphism in HLA and KIR genes and the impact on hematopoietic stem cell transplantation outcomes and unrelated donor selection: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].

abstract：:Multidrug resistant (MDR) phenotype is characterized by a defect in drug accumulation caused by overexpression of a transmembrane glycoprotein, the P-glycoprotein (P-gp). MDR phenotype can be characterized either with monoclonal antibodies raised against P-gp or with functional tests, most often based on the incorpora...

journal_title：Bulletin du cancer

authors： Lizard G,Maynadié M,Roignot P,Lizard-Nacol S,Poupon MF

更新日期：1995-03-01 00:00:00

abstract：:Cardiac neoplasms are a rare occurrence in clinical practice. The various frequencies of primary and secondary malignant tumors vary from report to report, approximately 1% in most autopsy series and 4% in cancer patient's autopsies. Cardiac malignancies account for less 1% of cardiac surgery and about for 0.1% of car...

journal_title：Bulletin du cancer

authors： Debourdeau P,Gligorov J,Teixeira L,Aletti M,Zammit C

更新日期：2004-11-01 00:00:00

abstract：:Management of unresectable metastatic colorectal cancer dramatically changed over the past 20 years. News standards of care combine cytotoxic drugs like fluoropyrimidines, irinotecan and oxaliplatin, with targeted therapies such as anti-EGFR monoclonal antibodies and anti-angiogenic agents. Survival benefit results fr...

journal_title：Bulletin du cancer

authors： Senellart H,Hiret S,Guerin-Meyer V,Bennouna J

更新日期：2014-06-01 00:00:00

abstract：:The treatment of chronic myeloid leukemia (CML) has considerably evolved since imatinib mesylate has been introduced as a new therapeutic weapon for this disease. The 5-year updated results of the IRIS study confirmed that imatinib mesylate is the best first line therapy for chronic phase CML with an overall survival ...

journal_title：Bulletin du cancer

authors： Labussière H,Hayette S,Tigaud I,Michallet M,Nicolini FE

更新日期：2007-10-01 00:00:00

abstract：:The high rate of recurrence after apparently complete surgery and/or complete clinical response to chemotherapy implies that most patients have undetected minimal residual disease. Novel techniques such as laparoscopic or laparotomic fluorescence may prove to be crucial in reassessing the definition of primary outcome...

journal_title：Bulletin du cancer

authors： Mery E,Golzio M,Thibault B,Ferron G,Querleu D,Delord JP,Couderc B

更新日期：2013-04-01 00:00:00

abstract：:The dependency between the risk of death and age is analysed, and the contribution of cancer to the overall risk of death is evaluated as a function of age. The frequency of the different cancer sites is described in different age groups. Lastly cancer mortality trends are presented by age. The risk of death from canc...

journal_title：Bulletin du cancer

authors： Hill C,Doyon F

更新日期：2008-05-28 00:00:00

abstract：:Docetaxel (Taxotère) has been developed in breast cancer during the last decade. First its activity in monotherapy was proven in metastatic setting after failure of anthracycline therapy. Then the association with anthracycline demonstrated substantial activity leading to its development in early stages of breast canc...

journal_title：Bulletin du cancer

authors： Diéras V,Girre V,Pierga JY,Laurence V,Piperno-Neumann S,Pouillart P

更新日期：2004-05-01 00:00:00

abstract：:Angiogenin is one of the most potent inducers of neovascularization in experimental models in vivo. Angiogenin is normally present in plasma but overexpressed in cancer patients. The possible involvement of angiogenin in the development of cancer is suggested by its overexpression in patients with a variety of tumours...

journal_title：Bulletin du cancer

authors： Pavlov N,Badet J

更新日期：2001-08-01 00:00:00

abstract：:For two decades, the prognostic of adult patients with ALL was improved based on pediatric-inspired protocols. These approaches based on less myelosuppressive drugs have led to improved response rates, decreased relapse rates, with a benefit in survival observed in patients aged up to 50-60-years-old. Therapeutic inte...

journal_title：Bulletin du cancer

authors： Rabian F,Boissel N

更新日期：2020-09-24 00:00:00

abstract：:Screening methods for the detection of anticancer activity are of crucial importance in order to find solid tumor-specific agents. A review of past screening methods is followed by a description of present methodologies targetted toward the discovery of such agents. Finally, we discuss primary and secondary in vivo ev...

journal_title：Bulletin du cancer

authors： Bissery MC,Chabot GG

更新日期：1991-01-01 00:00:00

abstract：:296 intraoral minor salivary gland tumors were observed among 702 salivary tumors. The study emphasizes a frequent palatine location, observed in more than 50 per cent of theses tumors. Pleiomorphic adenomas (or so called mixed tumors), are frequently encountered; but it is noteworthy that the proportion of muco-epide...

journal_title：Bulletin du cancer

authors： Brocheriou C,Crepy C,Guilbert F,Lartigau G,Payen J,Recoing J

更新日期：1980-01-01 00:00:00

abstract：:In terms of pharmacology, drug delivery is an important obstacle in the development of brain tumor chemotherapy. The blood-brain barrier limits the drug penetration in normal brain tissue around the tumor and at distant potential metastatic sites. In the tumor, the altered blood-brain barrier, ie blood-tumor barrier, ...

journal_title：Bulletin du cancer

authors： Vassal G

更新日期：1990-01-01 00:00:00

abstract：:mdm2 (mouse double minute) protein seems lead to p53 inactivation and therefore might potentially play a role in carcinogenesis. We have studied mdm2 gene amplification from 239 primary breast cancer tissues. mdm2 gene was amplified in 10% of cases (25/239). mdm2 amplification was associated with c-erbB2 amplification...

journal_title：Bulletin du cancer

authors： Fontana X,Ferrari P,Abbes M,Monticelli J,Namer M,Bussière F

更新日期：1994-07-01 00:00:00

abstract：:The dismal outcome of ovarian, fallopian tube, and primary peritoneal carcinomas calls for an increase in surgical aggressiveness. After a long era during which incomplete cytoreduction was considered acceptable, it has been established that the outcome is directly related to the amount of diseased tissue left in plac...

journal_title：Bulletin du cancer

authors： Querleu D,Gladieff L,Ferron G,Rougé P

更新日期：2009-12-01 00:00:00

abstract：:In recent years, Internet has become an indispensable tool for all types of information. Its importance has increased in medicine and particularly in human malignancies. The data issued by the Internet are many and varied sources ranging from official websites to patient's blogs. HIV infection is an infection highly p...

journal_title：Bulletin du cancer

authors： Cluzeau T,Mounier N

更新日期：2010-10-01 00:00:00

abstract：:The provision of medical care consumes resources, and the resources available for the provision of medical care are limited. Decisions are being made at many levels of the Health Care System, including providers and fiscal intermediaries, to allocate these resources. Such decisions, however, are often inconsistent wit...

journal_title：Bulletin du cancer

authors： Weinstein MC

更新日期：1980-01-01 00:00:00

abstract：:Protein phosphorylation is a fundamental post-translational modification. It regulates a large number of critical cellular processes (differentiation, division, proliferation, apoptosis). Cell division is a process including a series of phases by which a parent cell divides into two daughter cells. The cells enter the...

journal_title：Bulletin du cancer

authors： Carassou P,Meijer L,Le Moulec S,Aoun J,Bengrine-Lefèvre L

更新日期：2012-02-01 00:00:00

abstract：:Despite surgery, post-operative irradiation and adjuvant conventional chemotherapy, prognosis of high-grade gliomas remains poor. Carmustine (BCNU) has been shown to have limited activity at conventional dosage but is still the standard chemotherapy. Activity of chemotherapy is limited by the blood-brain barrier imper...

journal_title：Bulletin du cancer

authors： Linassier C,Destrieux C,Benboubker L,Alcaraz L,Bergemer-Fouquet AM,Jan M,Calais G,Colombat P

更新日期：2001-09-01 00:00:00

abstract：INTRODUCTION:The French Patient Advocacy Group SOS Desmoid conducted a survey to measure the pain burden of desmoid tumor patients. MATERIAL AND METHODS:We used a structured questionnaire to measure the occurrence and consequences of pain. RESULTS:The pain occurrence was approximately 63%. In one-third of the cases, ...

journal_title：Bulletin du cancer

authors： Rigaux P,Lefebvre-Kuntz D,Penel N,“SOS Desmoïde”.

更新日期：2015-03-01 00:00:00

abstract：:Oncolor, network in oncology in Lorraine, was born ten years ago, from a group of professionals in the field of oncology who worked closed together with regional administrative authorities. Oncolor was created with respect of equilibrium between the different regional partners avoiding struggle for power. Oncolor was ...

journal_title：Bulletin du cancer

authors： Bey P,Bouvier R,David M,Delena G,Garin H,Kessler Y,Klein I,Krakowski I,Lang MP,Leclercq JM,Level MC,Luron R,May I,Nabet M,Ruck S,Sommelet D,Theobald S,Unvois R,Walter S

更新日期：2004-07-01 00:00:00

abstract：:During the past two decades, the general acceptance of the surgical conservative treatments in tumors such as breast cancer, bone and soft tissue sarcoma, represents one of the significant steps achieved in the treatment of solid tumors. For low rectal cancer, abdominoperineal resection is considered the standard trea...

journal_title：Bulletin du cancer

authors： Allal AS

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:We analyzed renal cell carcinoma (RCC) brain metastasis (BM) risk factors and compared BM occurrence in metastatic RCC (mRCC) treated with or without anti-angiogenic agents (AA). METHODS:Data from all consecutive metastatic RCC patients (patients) treated in a french cancer center between 1995 and 2008 were...

journal_title：Bulletin du cancer

authors： Vanhuyse M,Penel N,Caty A,Fumagalli I,Alt M,Zini L,Adenis A

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:The diagnosis of chronic myeloid leukemia is based on the presence of translocation t(9,22). Additional cytogenetic abnormalities may exist at diagnosis and have prognostic value. The authors evaluated the relationship between these additional chromosomal abnormalities, clinical presentation, and therapeut...

journal_title：Bulletin du cancer

authors： Silué DA,Kouakou B,Nanho CD,Kamara I,Djoko S,Sowhe T,Meité N,Ayemou R,Emeuraude N,Tolo A,Koffi G,Sanogo I

更新日期：2019-06-01 00:00:00

abstract：:Despite great improvements in the outcome of patients with lymphoma, some may still relapse or present with primary refractory disease. In these situations, allogeneic hematopoietic cell transplantation is a potentially curative option, this is true particularly in the case of after autologous stem cell transplantatio...

journal_title：Bulletin du cancer

authors： Gauthier J,Chantepie S,Bouabdallah K,Jost E,Nguyen S,Gac AC,Damaj G,Duléry R,Michallet M,Delage J,Lewalle P,Morschhauser F,Salles G,Yakoub-Agha I,Cornillon J

更新日期：2017-12-01 00:00:00

abstract：:Aprepitant is actually recommended in the prevention of nausea and vomiting induced by high emetic risk chemotherapy using cisplatin. We performed an observational prospective study on 101 patients evaluating the efficacy of aprepitant in the clinical conditions of use of cisplatin, out of context of clinical trial. W...

journal_title：Bulletin du cancer

authors： Galy G,Labidi SI,Tissier F,Combes JD,Auger A,Favier B,Latour JF

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:Systematic metastasis staging in early breast cancer is no longer recommended. However, it is still performed before adjuvant chemotherapy. MATERIALS AND METHODS:We assessed metastasis screening of asymptomatic women with a local breast cancer without lymph node involvement when adjuvant chemotherapy was ...

journal_title：Bulletin du cancer

authors： Thonnon C,Faure C,Chopin N,Beurrier F,Ho Quoc C,Tredan O,Carrabin N

更新日期：2015-05-01 00:00:00

abstract：:BRCA is a tumor suppressor gene implicated in the major mechanisms of cellular stability in every type of cell. Its mutations are described in numerous cancers, mainly breast and ovarian in women. It was also found an increase of lifetime risk of pancreas, colon, prostate cancer or lymphoma in men carriers. We report ...

journal_title：Bulletin du cancer

authors： Girardstein-Boccara L,Mari V,Met-Domestici M,Burel-Vandenbos F,Berthet P,Paquis P,Frenay MP,Lebrun-Frenay C

更新日期：2014-09-01 00:00:00

abstract：:Laparoscopy for malignancy resection has been followed by description of metastatic laparoscopic port sites. Recently published clinical, experimental studies and case reports related to this problem are reviewed. Frequency of port-site metastases for gallbladder, colorectal and ovarian cancers seem to differ. Ascites...

journal_title：Bulletin du cancer

authors： Agostini A,Camatte S,Farthouat P,Blanc B,Lecuru F

更新日期：2000-12-01 00:00:00

abstract：:Combination of radiotherapy and androgen deprivation is now considered as the standard of care for patients with a localized prostate cancer but poor prognostic factors. Two groups of randomized trials have led to this recommendation. Some have compared radiotherapy alone versus hormonal treatment and radiotherapy: th...

journal_title：Bulletin du cancer

authors： Quero L,Wong-Hee-Kam S,Rivera S,Hennequin C

更新日期：2012-07-01 00:00:00

abstract：:The authors report on a case of a woman with acute lymphoblastic leukemia treated with cortisone therapy during pregnancy. No problems were encountered during the gestational period or at parturition; and no maternal or neonatal complications were observed. ...

journal_title：Bulletin du cancer

authors： Hamdoun L,Zeineb NB,Ferchiou M,Zhioua F,Meriah S

更新日期：1992-01-01 00:00:00