Abstract:
:Combination of radiotherapy and androgen deprivation is now considered as the standard of care for patients with a localized prostate cancer but poor prognostic factors. Two groups of randomized trials have led to this recommendation. Some have compared radiotherapy alone versus hormonal treatment and radiotherapy: these trials demonstrated, now with a long follow-up, an improvement in 10-year survival for the combined treatment. Three recent trials compared androgen deprivation alone or combined with radiotherapy; a benefit in survival was also demonstrated in favour of the combination. Some questions remained concerning the optimal duration of hormonal treatment, in view of its potential side effects. Patients in the intermediate prognostic groups could receive a short-term androgen deprivation, but those with a high Gleason score must be treated with a long-term hormonal treatment. Modalities of radiotherapy, regarding volumes and dose must also be precised in the next years.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Quero L,Wong-Hee-Kam S,Rivera S,Hennequin Cdoi
10.1684/bdc.2012.1567subject
Has Abstractpub_date
2012-07-01 00:00:00pages
S30-6eissn
0007-4551issn
1769-6917pii
bdc.2012.1567journal_volume
99 Suppl 1pub_type
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
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doi:
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journal_title:Bulletin du cancer
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更新日期:2007-10-01 00:00:00
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journal_title:Bulletin du cancer
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更新日期:2003-01-01 00:00:00
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
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journal_title:Bulletin du cancer
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