Abstract:
:Advances in medical imaging have greatly enhanced the speciality of radiation oncology by allowing more healthy tissue to be speared for better tumour coverage. Positron emission tomography (PET) with the glucose analogue [18F]-fluoro-2-deoxy-D-glucose (FDG) is a functional imaging method that has become widely used in oncology over the last decade. It has been rapidly incorporated in the staging and treatment planing of many patients with cancer in several anatomic sites such as non-small cell lung carcinomas. However, the initial data were controversial by the use of non dedicated PET units, the lack of patient immobilisation for radiation therapy, or the lack of image registration for fusion PET images with computed tomography (CT). The increased number of combined PET/CT units installed and the development of new isotopes that allow advances in biological and molecular tumour and healthy tissue imaging should lead to enhanced target definition for highly conformal radiation therapy. Such developments might also allow tumour viability or healthy tissue function to be imaged, which could be used during treatment as early indicators of tumour response or healthy tissue injury, possibly leading to a change in treatment strategy based on functional and biological imaging. The contribution of PET imaging advances using FDG or new tracers for treatment planing in the new era of image guided radiation therapy will be discussed in this review.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Belkacémi Y,Lartigau E,Kerrou K,Carpentier P,Taïeb S,Giraud Psubject
Has Abstractpub_date
2007-01-01 00:00:00pages
99-108issue
1eissn
0007-4551issn
1769-6917journal_volume
94pub_type
杂志文章,评审abstract::296 intraoral minor salivary gland tumors were observed among 702 salivary tumors. The study emphasizes a frequent palatine location, observed in more than 50 per cent of theses tumors. Pleiomorphic adenomas (or so called mixed tumors), are frequently encountered; but it is noteworthy that the proportion of muco-epide...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::The aims of this study was to estimate and describe the reasons of use of complementary medicine in patients with a cancer treated in a French oncology department. An anonymous questionnaire was proposed to patients during treatment or follow-up in an oncology department. It was a descriptive study over 207 questionna...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2007-11-01 00:00:00
abstract::This study was performed in a group of 89 patients treated for breast carcinoma with a FEC regimen (5-fluorouracil, epirubicin, cyclophosphamide). The aim was to evaluate the antiemetic efficacy of one 8 mg tablet ondansetron (OND), and in case of failure, to measure the recovering level by the administration of 8 mg ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::The study of cases treated between 1970 and 1984 at the Institut Curie, in women aged 40 years and under, was undertaken in order to determine the influence of age on prognosis. The incidence of these cases was stable throughout the 15 years study period as was the very high incidence of earlier cases: 84.5%. Earlier ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::An increasing number of clinicians is to day aware of the need to assess their diagnostic tools. Despite the fact that monetary value is only one of the components of the cost of a diagnostic test, economical problems are decisive stimuli for such an effort. Any diagnostic test involves a cost which is borne by the pa...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::All the retrospective and prospective studies concerning IORT in tumors of the digestive tract tend to substantiate a significant improvement in local control without a significant increase in survival. Improvements in the results of IORT can be expected in the near future, and may occur on several fronts: - Technolog...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-02-01 00:00:00
abstract::The authors report a case of endometrial carcinoma treated with tamoxifen introduced after normal initial uterine curettage. Based on recent experimental and clinical data, the importance of a gynecological follow-up in anti-estrogen therapy is emphasized. ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::Since January 1981, 58 patients with postoperative recurrences or inoperable rectal cancer have been included in a trial featuring a neutron boost after an initial series of irradiation given by the classical high energy photon procedure. This group irradiated at the Neutrontherapy Unit in Orléans was compared to a hi...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::In response to the evolution of the information-seeking behaviour of patients and concerns from health professionals regarding cancer patient information, the French National Federation of Comprehensive Cancer Centres (FNCLCC) introduced, in 1998, an information and education program dedicated to patients and relative...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract::The presence of hypoxic regions within solid tumours is associated with a more malignant tumour phenotype and worse prognosis. To obtain a blood supply and protect against cellular damage and death, oxygen-deprived cells in tumours alter gene expression, resulting in resistance to therapy. Hypoxia is sensed at the cel...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2007-07-01 00:00:00
abstract::This year, the innovations were numerous in sarcomas. Important progress were accomplished in the search for predictive factors which make it possible to propose to the patient a personalized treatment with the therapeutic ones reduced in the event of good prognosis or on the contrary aggressive steps in the event of ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:An increasing number of patients with prostate cancer (PC) are diagnosed and treated. The aim of this study was to investigate urinary incontinence (UI) and sexual dysfunction (SD) two years after treatment for localized prostate cancer (PC). METHODS:This study followed all cases of localized PC diagnosed...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2016.09.011
更新日期:2016-10-01 00:00:00
abstract::The potential doubling time (Tpot) is defined as the time necessary to double the number of proliferating tumor cells in the absence of spontaneous cell loss. Tpot is thought to be a better index of tumor proliferation than clinically observed tumour volume doubling time. The in vivo measurement of Tpot is a possible ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::A suspension of CE "44" embryoïd-bodies obtained from a transplanted OTT 60-50 subline was injected into the abdominal cavity of syngeneic L 129 mice. Terato-carcinoma and ascitic fluid were produced the latter containing embryoïds. In situ examinations were made by serial transverse sectioning of the entire abdomen. ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::In the last ten years considerable progress has been made in small-cell lung carcinoma (SCLC) biology, along with the technical progress made in molecular biology. This progress now allows us to propose a model for the genesis and the development of this type of tumor. Tobacco, the principal causal factor plays a dual...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Asbestos is known as mutagenic and carcinogenic for human and is responsible for many pulmonary diseases including asbestosis, bronchogenic carcinoma and malignant pleural mesothelioma. Occupational exposure to asbestos is involved in 70-80% of all malignant pleural mesothelioma. The later presents a growing challenge...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2005-11-01 00:00:00
abstract::The higher human and material costs induced by the development of conformal radiotherapy and other innovative techniques have to be evaluated. Different studies reflect benefit for three-dimensional conformal radiation therapy. This needs appropriate economic analyses (cost/benefit, cost/utility). Conclusions from stu...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract::Gemtuzumab ozogamicin (GO) is a humanized monoclonal antibody anti-CD33 conjugated with calicheamicin and was indicated for acute myeloid leukemia (AML) patients. It was initially approved in 2000 by FDA thank to promising results from a phase II trial including elderly relapsing AML patients. Numerous studies evaluat...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2014.1886
更新日期:2014-02-01 00:00:00
abstract:CONTEXT:The maxillo-facial attack was the first described in the Burkitt lymphoma in 1958 by Denis Pearsons Burkitt. Abdominopelvic disorders, particularly ovarian localization are observed more and more by the developments of imagery technics. Our study aimed to describe the epidemiologic, clinical, therapeutic and ev...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2018.12.011
更新日期:2019-03-01 00:00:00
abstract::The network of cancer care units in Lorraine area (Oncolor) developed management training for people working in chemotherapy units, and cytotoxic drug preparation. The programme was framed both for staff of executives (pharmacists), and technicians. Firstly, comparison between practices and theoretical recommendations...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract::Despite surgery, post-operative irradiation and adjuvant conventional chemotherapy, prognosis of high-grade gliomas remains poor. Carmustine (BCNU) has been shown to have limited activity at conventional dosage but is still the standard chemotherapy. Activity of chemotherapy is limited by the blood-brain barrier imper...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-09-01 00:00:00
abstract::The diet of the cancer patient is a major focus of prevention and treatment strategy of the recent plans that fight against cancer. It is sometimes reduced to a rapid series of more or less general advice, often interfered by other sources of information, more or less conventional. In this pathological situation where...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2014.1905
更新日期:2014-03-01 00:00:00
abstract::Cancer growth and metastasis require the coordinate change in gene expression of different sets of genes. While genetic alterations can account for some of these changes, many of the changes in gene expression observed in cancer are caused by epigenetic modifications. The epigenome consists of the chromatin and its mo...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::Thymidine kinase (TK) was assayed in the cytosol of 210 primary breast cancers to assess its predictive value for response to first line chemotherapy and hormonotherapy. We performed correlations between TK and the other prognosis factors of breast cancer. TK activity is correlated with SBR grading and estrogen recept...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Metastases are responsible for the majority of deaths from solid cancers. Metastatic phenomenon, complex, is a multi-step process where interactions between cells and with the microenvironment are essential. The organ tropism, that is the propensity of a cancer to metastasize to specific organs, can be explained by se...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2014.1889
更新日期:2014-02-01 00:00:00
abstract::Twenty-five adult patients, 15 men and 10 women, with a median age of 49, and presenting with metastatic or locally advanced soft tissue sarcomas, have been treated with chemotherapy protocol combining cisplatinum, 100 mg/m2, vindesine, 4 mg/m2, and either adriamycin, 50 mg/m2 (APEL) (16 patients), or epirubicin, 100 ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Having to start chemotherapy during pregnancy remains a rare event. The decision to proceed this treatment relies on the drugs used, the time of exposure for the foetus and the gestational age at the time of exposure. As a matter of fact, the mutagenicity potential of the chosen medicine has to be known, and consequen...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract::The biological diagnosis of prostatic carcinoma in relation with benign prostatic hypertrophy is essentially realized by the evaluation of plasma PAP or medullar PAP, the increase of which rises to 70% of the cases. This evaluation contains also other biochemical markers such as CK-BB, glucose-6-phosphate dehydrogenas...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::The estimated number of cancers diagnosed in 2002 is 150,000 in the male population and 120,000 in the female population and there were close to 88,000 cancer deaths among men and 59,000 cancer deaths among women in France. The most frequent cancer sites in the male population are prostate, lung, colon, intestine and ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Urothelial tumors are very rare in children (to date, only about 150 cases have been reported worlwide). Only 20% occur before the age of ten. The aim of this study is to specify the clinicopathologic features of urothelial tumor in young patients, which require a slightly different approach to treatment. On the basis...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2016.11.018
更新日期:2017-02-01 00:00:00