[Value of thymidine kinase in the prediction of response to treatment by chemotherapy or hormone therapy in breast cancer].

Abstract:

:Thymidine kinase (TK) was assayed in the cytosol of 210 primary breast cancers to assess its predictive value for response to first line chemotherapy and hormonotherapy. We performed correlations between TK and the other prognosis factors of breast cancer. TK activity is correlated with SBR grading and estrogen receptors. It has a low predictive value for response to chemotherapy and is not useful for hormonotherapy.

journal_name

Bull Cancer

journal_title

Bulletin du cancer

authors

Bennini N,Mauriac L,Wafflart J,Bonichon F,Durand M

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

773-9

issue

8

eissn

0007-4551

issn

1769-6917

journal_volume

79

pub_type

杂志文章
  • [Adjuvant chemotherapy in cancers of the stomach, pancreas and intestine].

    abstract::Adjuvant chemotherapy after apparently complete resection of gastrointestinal cancer may be theoretically justified by the high rate of local and metastatic recurrences. However, the results of controlled trials are generally disappointing, even if some of them have recently suggested some hope, chiefly for adjuvant t...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Martin F

    更新日期:1984-01-01 00:00:00

  • [Results of a combination of platinum-vindesin-ametycin-bleomycin (CEMB) in the treatment of stage IV non-small-cell lung cancers].

    abstract::From July 1987 to July 1988, 35 patients with non small cell lung cancer, stage IV, were included in a phase II trial (GLOT NPC 87/01). The treatment was as follows: cisplatin 50 mg/m2 day 1, vindesin 3 mg/m2 day 1, mitomycin 6 mg/m2 day 2, and bleomycin 15 mg/day, day 1 + 2 by continuous infusion. The evaluation for ...

    journal_title:Bulletin du cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Souquet PJ,Fournel P,Jorda M,Laennec E,Piperno D,Trillet V,Rebattu P,Bernard JP

    更新日期:1993-01-01 00:00:00

  • [Histological and immunohistochemical diagnosis of bone marrow metastases of neuroblastomas].

    abstract::A retrospective, morphological and immunochemical study was performed on 60 bone marrow biopsies (BOM) and 12 tumor specimens surgically excised, from 9 patients with neuroblastoma (NB). Immunochemistry concerned "neuron-specific enolase" (NSE), chromogranin A (CGA) and synaptophysin (SP). The results of immunochemica...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Boman F,Chastagner P,Floquet J,Sommelet D,Aymard B,Palau R,Kleinclaus I

    更新日期:1991-01-01 00:00:00

  • [Limitations of palliative chemotherapy, application to lung cancer: the point of view of hospital pharmacists].

    abstract::In our hospital, most of the patients with a cancer received palliative chemotherapy. Then, we wanted to know in which conditions these therapies were realised and most specially for patients with lung cancer. We noted the stage of the disease at the diagnosis, the median survival duration after diagnosis and the medi...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Demange C,Thiébaux I

    更新日期:2003-03-01 00:00:00

  • [Prognostic factors in multiple myeloma. Review of the literature].

    abstract::Apparition of new tools in the therapy of multiple (MM) strengthens the need for valuable prognostic categorization of each patient in order to propose the most adequate treatment. Prognostic factors in MM can be divided in four groups. The first, including beta 2 microglobulin (beta 2m), hemopoiesis impairment, osteo...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Bauduer F,Troussard X,Delmer A

    更新日期:1993-12-01 00:00:00

  • Altered glucose metabolism in intact and tumor bearing rats subjected to local hyperthermia.

    abstract::Blood glucose levels were temporarily elevated in normal and in tumor bearing Lewis rats subjected to one local hyperthermic treatment in the leg or in the upper abdomen. Serum transferred from locally heated animals or serum heated in-vitro and injected to normal recipients resulted in elevated blood glucose levels. ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Beer-Gabel M,Yerushalmi A

    更新日期:1981-01-01 00:00:00

  • [Magnetic resonance imaging of desmoid-type fibromatosis: Current evaluation criteria].

    abstract::The management of desmoid-type fibromatosis has considerably evolved these last years, toward first-line active surveillance then systemic or local symptomatic treatment in case of aggressive tumor. Magnetic resonance imaging is the modality of choice in each of these treatment settings. It needs multiparametric appro...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1016/j.bulcan.2019.11.009

    authors: Ben Haj Amor M,Ploton L,Ceugnart L,Taïeb S

    更新日期:2020-03-01 00:00:00

  • [Fertility and the progeny of children surviving cancer treatment (author's transl)].

    abstract::Little is known about the late effects of damage to the gonads in children treated for cancer. This investigation requires a prolonged surveillance. Radiotherapy sterilizes the ovaries above a dose of about 500 rads in an adult. Therefore, to protect at least one ovary in partial irradiation of a child's abdomen in ma...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Flamant F,Schweisguth O

    更新日期:1979-01-01 00:00:00

  • [Medicinal plants in cancer patients: current practices and evaluation data].

    abstract::Many complementary and alternatives medicines are offered to patients with cancer. Among them, herbal medicines have a substantial place. These plants are mainly used to reduce adverse effects of anticancer treatments and for specific anticancer properties. Our review shows that only few clinical data support medicina...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2013.1741

    authors: Huet M

    更新日期:2013-05-01 00:00:00

  • [Role of adjuvant chemotherapy in the treatment of soft tissue sarcoma].

    abstract::Important improvements in local control with increasing function-sparing treatment have been achieved in adult soft tissue sarcomas (STS). However, the global prognosis of these diseases remains poor and 40% of patients with STS currently die of metastases within 5 years. In fact, the impact of chemotherapy remains de...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,meta分析

    doi:

    authors: Debled M,Ravaud A,Stöckle E,Nguyen BB

    更新日期:1997-06-01 00:00:00

  • [Squamous cell anal carcinoma. What's next ?]

    abstract::Despite its status as a rare disease, the incidence of the squamous cell carcinoma of the anus (SCCA) is surging, especially in its metastatic form. In addition, the prognosis of initially localized diseases has not substantially changed since the 1970s with a recurrence rate of between 25-40 % after the chemoradiothe...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2020.12.001

    authors: Kim S,Spehner L,Cabel L,Bidard FC,Borg C

    更新日期:2021-01-01 00:00:00

  • [Experimental terato-carcinoma: behavior of embryoid bodies inoculated into the abdominal cavity of syngeneic mice].

    abstract::A suspension of CE "44" embryoïd-bodies obtained from a transplanted OTT 60-50 subline was injected into the abdominal cavity of syngeneic L 129 mice. Terato-carcinoma and ascitic fluid were produced the latter containing embryoïds. In situ examinations were made by serial transverse sectioning of the entire abdomen. ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Gaillard JA

    更新日期:1976-07-01 00:00:00

  • [Cured after an intraocular tumor].

    abstract::We describe the psychological reactions after diagnosis and treatment of the malignant intraocular tumors: uveal melanoma and retinoblastoma. The chapter on uveal melanoma includes general consideration on the treatment of these tumors, the psychological effects on the patients, the professional and social problems, t...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Desjardins L,Delage M,Lumbroso L,Levy C,Doz F

    更新日期:2001-11-01 00:00:00

  • [Molecular biology of sarcoma and therapeutic choices].

    abstract::Soft tissue sarcomas (STS) are a set of very heterogeneous tumors with numerous histological categories. The development of the molecular biology allowed identifying recurring molecular anomalies in certain subgroups of sarcomas, being able to represent diagnostic, prognosis and therapeutic tools. The molecular classi...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2014.12.005

    authors: Dufresne A,Cassier P,Heudel P,Pissaloux D,Wang Q,Blay JY,Ray-Coquard I

    更新日期:2015-01-01 00:00:00

  • [The cost of radiotherapy].

    abstract::The higher human and material costs induced by the development of conformal radiotherapy and other innovative techniques have to be evaluated. Different studies reflect benefit for three-dimensional conformal radiation therapy. This needs appropriate economic analyses (cost/benefit, cost/utility). Conclusions from stu...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Martin P

    更新日期:2003-11-01 00:00:00

  • [Colorectal cancers disclosed by an obstruction. Frequency and prognosis in a population].

    abstract::The registry of digestive tumors of the department of Cote-d'Or recorded between 1976 and 1982, among 1543 colorectal cancers, 142 cases (9.2%) diagnosed with acute obstruction. Distribution of the tumors along the large bowel was as follows: rectal cancers were rarely obstructive (3.8%) whereas it was a more common f...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Boutron MC,Faivre J,Rallier du Baty H,Meny B,Bedenne L,Hillon P,Klepping C

    更新日期:1988-01-01 00:00:00

  • A phase I-II, dose-escalating trial of ZD9331 in combination with irinotecan (CPT11) in previously pretreated metastatic colorectal cancer patients.

    abstract:BACKGROUND:To establish the recommended dose (RD) of the thymidylate-synthase inhibitor ZD9331 administered with irinotecan (CPT-11) in patients with pretreated metastatic colorectal cancer, and to assess toxicity profile, pharmacokinetics (PK), and anti-tumor activity in a phase I/II open, multicenter, intrapatient ch...

    journal_title:Bulletin du cancer

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Louvet C,André T,Gamelin E,Garcia ML,Saavedra A,Lenaers G,de Gramont A,Méry-Mignard D,Kalla S

    更新日期:2004-12-01 00:00:00

  • [DNA mismatch repair and BRAF status in colorectal cancer: Interest for the therapeutic management?].

    abstract::Colorectal cancer (CRC) is the second leading cause of cancer-related mortality in France. Recently, colorectal cancer subtyping consortium (CRCSC) identified 4 consensus molecular subtypes (CMS). CMS1 is enriched for CRC with deficient DNA mismatch repair system (dMMR) and tumors with mutated BRAF. Intriguingly, CMS1...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/S0007-4551(15)31220-0

    authors: Cohen R,Cervera P,Svrcek M,Dumont C,Garcia ML,Chibaudel B,de Gramont A,Pocard M,Duval A,Fléjou JF,André T

    更新日期:2015-06-01 00:00:00

  • [Invasive cancer of the uterine cervix in young women: retrospective study of 236 cases].

    abstract::The study of cases treated between 1970 and 1984 at the Institut Curie, in women aged 40 years and under, was undertaken in order to determine the influence of age on prognosis. The incidence of these cases was stable throughout the 15 years study period as was the very high incidence of earlier cases: 84.5%. Earlier ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Fenton J,Chevret S,Asselain B,de La Rochefordière A,Mathieu G,Labib A,Durand JC,Salmon RJ

    更新日期:1990-01-01 00:00:00

  • [Improving doctor's communication skills in oncology: review and future perspectives].

    abstract::The aim of this review is to discuss the different communication skills training designed to physician interactions with cancer patients. The development of medicine and chronic cancer treatments indicates the need to improve communication skills that combine appropriate assessment, information and support. Literature...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Libert Y,Conradt S,Reynaert C,Janne P,Tordeurs D,Delvaux N,Fontaine O,Razavi D

    更新日期:2001-12-01 00:00:00

  • [Chemotherapy-induced peripheral neuropathy: Symptomatology and epidemiology].

    abstract::Chemotherapy-induced peripheral neuropathy (CIPN) is common with specific semiological characteristics. When CIPN appears, there are many difficulties in guaranteeing sustained treatment, especially with optimal protocol. Moreover, CIPN have bad repercussions on quality of life after cancer disease. In this article, w...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2018.07.009

    authors: Kerckhove N,Collin A,Condé S,Chaleteix C,Pezet D,Balayssac D,Guastella V

    更新日期:2018-11-01 00:00:00

  • Evaluating the influence of prophylactic central neck dissection on TNM staging and the recurrence risk stratification of cN0 differentiated thyroid carcinoma.

    abstract:OBJECTIVE:The purpose of this study was to explore the risk factors that were associated with central lymph node metastasis (CLNM) in patients with clinical nodal negative differentiated thyroid carcinoma (cN0 DTC) after prophylactic central neck dissection (pCND). The influence of pCND on TNM staging and recurrence ri...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1016/j.bulcan.2016.04.003

    authors: Lin X,Chen X,Jiru Y,Du J,Zhao G,Wu Z

    更新日期:2016-06-01 00:00:00

  • On the value of response criteria in therapeutic research.

    abstract::Primary chemotherapy is the use of anticancer drugs as the first treatment in patients with localized tumor presentations for which there is an alternative but less than satisfactory treatment. Its most important feature is the preservation of the primary tumor mass as a biologic marker of response, and in this sense ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Devita VT Jr

    更新日期:1988-01-01 00:00:00

  • [What's new in the treatment of cancer pain?].

    abstract::Improvements have been made recently in the treatment of cancer pain. First of all, this symptom is better recognized and evaluated in cancer patients. Then new therapeutic options have became available in France : tramadol, WHO level II analgesic, for intermediate to severe pain; gabapentine, a new anticonvulsivant d...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Di Palma M,Poulain P,Pichard E

    更新日期:2004-01-01 00:00:00

  • [Treatment of peritoneal carcinomatosis with surgery and hyperthermic peroperative intraperitoneal chemotherapy (HIPEC): new aspects and validated indications].

    abstract::Hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) is now an entire part of treatment of peritoneal dissemination of colorectal malignancy, and it's possible to hope prolonged survival. This treatment is more and more codified. Four indications are recognized by some tree national evaluation committees: ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2008.0553

    authors: Eveno C,Dagois S,Guillot E,Gornet JM,Pocard M

    更新日期:2008-01-01 00:00:00

  • [Colorectal liver metastases: history, sciences and clinical practices].

    abstract::Colorectal liver metastasis is one of the best-known clinical models of multidisciplinary approach. Chemotherapy, targeted therapies, surgery and interventional radiology permitted to obtain up to 40 months of survival in palliative intent for liver metastases only and between 40 to 50% of overall survival in curative...

    journal_title:Bulletin du cancer

    pub_type: 历史文章,杂志文章,评审

    doi:10.1684/bdc.2014.1930

    authors: Evrard S

    更新日期:2014-04-01 00:00:00

  • Quality of care assessment for breast cancer: how to measure benefits of prevention and therapy in oncology.

    abstract::Over the last few years evaluation of quality of diagnostic and therapeutic care has become one of the most controversial and fastest growing fields of research in many areas of medicine. In this situation, oncology represents a model case as the conditions in which new therapeutic strategies are tested and implemente...

    journal_title:Bulletin du cancer

    pub_type: 临床试验,杂志文章

    doi:

    authors: Liberati A,Fossati R,Torri W

    更新日期:1987-01-01 00:00:00

  • [Gemcitabine and pemetrexed in genito-urinary tumors treatment].

    abstract::Among genito-urinary tumors, gemcitabine is indicated only for the treatment of locally advanced and metastatic urothelial cancer. The combination of gemcitabine and cisplatin is a new standard in this disease. Gemcitabine shows activity in refractory germ cell tumors. In salvage treatment its role is ongoing evaluati...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Fléchon A

    更新日期:2007-01-01 00:00:00

  • [Role of surgery in the treatment of cancer. Surgical oncology].

    abstract::Surgical oncology requires an indispensable cultural and interdisciplinary approach of cancer. It needs a solid surgical formation combined with knowledges in biology, pathology, radiology, chemotherapy, and radiotherapy so oncologist surgeons are better able to define the limits of intervention according to the natur...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Bobin JY,Delay E,Rivoire M

    更新日期:1995-01-01 00:00:00

  • [Methodology and limitations of pre-clinical models for the development of anticarcinogenic chemotherapy combinations].

    abstract::In chemosensitive tumors, cancer chemotherapy is active as drug combinations. During the development of new anticancer drugs, preclinical experimental models may help to design drug combinations. Indeed, in vitro models are able to define drug interactions in terms of synergism, additivity or antagonism, while in vivo...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Vassal G

    更新日期:1998-11-01 00:00:00