Abstract：
:In our hospital, most of the patients with a cancer received palliative chemotherapy. Then, we wanted to know in which conditions these therapies were realised and most specially for patients with lung cancer. We noted the stage of the disease at the diagnosis, the median survival duration after diagnosis and the median time between the last treatment and death. We also noticed the chemotherapy incidents: decrease of dosage, postpone or cancel of a treatment, change of drugs. For the year 2000, 84 patients received chemotherapy, 30 died whom 17 with lung cancer. Diagnosis was done at a metastatic disease (stage IV) in 70.6% of patients with lung cancer. Then, median duration between diagnosis and death is 4 months, median time between last treatment and death is 13 days. Platinium's salts were chiefly used, combined with vinorelbine. 64.7% of patients with lung cancer had either toxicity or outlet, and 70.6% received a chemotherapy treatment during the last month before death. In our hospital, diagnosis of cancers specially lung cancers are late. Then, patients are treated palliatively with a small improvement and a not negligible toxicity. Therefore chemotherapy is carried on, even if it is hopeless.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Demange C,Thiébaux Isubject
Has Abstractpub_date
2003-03-01 00:00:00pages
284-8issue
3eissn
0007-4551issn
1769-6917journal_volume
90pub_type
杂志文章abstract：:Hodgkin's and non-Hodgkin's lymphomas are frequent and represent a heterogenic group of haematologic diseases. Prognostic factors allow to classify patients into homogeneic risk groups, to adapt treatment proposal to disease's risk and, in some cases, to avoid over-treatment. For all lymphomas, the first step is to de...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2009.0844
更新日期：2009-04-01 00:00:00
abstract：:Basal-like carcinomas represent 10 to 15% of invasive breast carcinomas and have been identified from gene expression studies. Morphologically, these tumors are undifferentiated histopronostic grade 3 carcinomas, identified in clinical practice according to their immunophenotype "triple zero" (estrogen, progesterone a...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2010.1062
更新日期：2010-03-01 00:00:00
abstract：UNLABELLED:This CORCAN study is concerned with the way patients hospitalised for peritoneal carcinosis perceive surgical treatment and hyperthermic intraperitoneal chemotherapy (HIPEC). OBJECTIVES:(1) To identify and analyse, using concepts of social representation and accounts of the illness, characteristics of the w...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/j.bulcan.2015.10.015
更新日期：2016-02-01 00:00:00
abstract：:This paper recalls the definition of the Gleason index and describes the five architectural types that enable a calculation of the index. The conditions of the practical application of the index are defined, with a discussion of reproducibility of results based on current literature and the author's experience. The in...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:With 2 436 deaths in 1979, ovarian cancer is relatively infrequent in France comprising but 5 per cent of female mortality from malignant disease. However, the rate of increase in mortality is considerable, 70 per cent between 1955 and 1979 or 2,9 per cent per year, greater than that for female bladder and breast canc...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Announcing a cancer diagnosis, but also a relapse, a progression of the disease, or transition towards palliative care constitute particularly difficult communication issues for the patient as well as for the clinician, during the trajectory of care. The objectives of this article is to present the clinical stakes of ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2010.1197
更新日期：2010-10-01 00:00:00
abstract：:This paper reviewed the 2002 guidelines established by the National Federation of Cancer Centres. A group of experts nominated by the 3 French Societies involved in the treatment of cancer pain (AFSOS, SFAP, SFETD), established new guidelines ratios for morphine switching and/or changing of route of administration, in...
journal_title：Bulletin du cancer
pub_type： 杂志文章,实务指引,评审
doi：10.1016/j.bulcan.2018.06.011
更新日期：2018-11-01 00:00:00
abstract：:The organization of the management of pain and other symptoms all along the cancer disease, of psychological support and palliative care is a complex question that does not correspond to any perfectly established model, both in France and abroad. Different structures are implied in there care and coexist with an insuf...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：:Due to immunotherapy, a new era of treatment is opening up for the treatment of solid cancers and hematological tumors. T cells genetically modified with a chimeric antigen receptor (CAR-T cells) have recently been proved efficient in hematological malignancies expressing CD19. On June 20th 2018, the European Medicine...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/j.bulcan.2018.08.001
更新日期：2018-09-01 00:00:00
abstract：:The relationships involved in host resistance to tumor development were studied. Animals were pretreated by local hyperthermia, local irradiation and combined local hyperthermia and x-irradiation. After treatment, the animals were inoculated with tumor cells 0--96 or 0--120 hours post treatment. (BALB/c X C57B1/6)F1 m...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:A retrospective, morphological and immunochemical study was performed on 60 bone marrow biopsies (BOM) and 12 tumor specimens surgically excised, from 9 patients with neuroblastoma (NB). Immunochemistry concerned "neuron-specific enolase" (NSE), chromogranin A (CGA) and synaptophysin (SP). The results of immunochemica...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Breast cancer (BC) has the highest incidence rate in women in industrialized countries. Statistically, it is estimated that one out of 10 women will develop BC during her life. Evidence is accumulating for the role of ion channels in the development of cancer. Most studied ion channels in BC are K(+) channels, which a...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2012.1595
更新日期：2012-06-01 00:00:00
abstract：:Tamoxifen is widely used nowadays in the management of breast cancer, having established its efficacy in this indication, especially for postmenopausal patients with ER-positive breast tumours. However, tamoxifen has recently been recognized as carcinogenic for the human endometrium, probably with an effect of duratio...
journal_title：Bulletin du cancer
pub_type： 临床试验,杂志文章,多中心研究,评审
doi：
更新日期：1997-01-01 00:00:00
abstract：:The rising incidence of cancers affecting the kidney emphasizes the need to identify the molecular pathways involved in the initiation and progression of kidney tumors in order to counter this phenomenon. For many years, genes belonging to the PAX family have been the focus of intensive studies in the fields of organo...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2006-09-01 00:00:00
abstract：BACKGROUND AND AIM:CABYR, a calcium-binding tyrosine phosphorylation regulated fibrous sheath protein, was initially reported to be testis-specific and subsequently shown to be present in brain tumors, pancreas cancer and lung cancer. This study aimed to investigate the expression and effects of the CABYR-c transcript ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2011.1538
更新日期：2012-03-01 00:00:00
abstract：:PDQ is an online database that provides information about the prognosis and treatment of all major types of cancer. It represents a major effort by the NCI to communicate advances in cancer treatment using computer technology, and serves as a major component of the Institute's program to reduce cancer mortality nation...
journal_title：Bulletin du cancer
pub_type： 临床试验,杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:From 1941, estrogens are usually used in the treatment of prostatic carcinoma, wrongly in case of adjuvant hormonotherapy and exceedingly because of cardiovascular toxicity from over dosages. A recall of their mechanism of action and toxicity allows to argue about the palliative treatment and to look to their use for ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:When a metastatic disease is localized and slowly evolving either spontaneously or after a general treatment, a local treatment may be proposed. For about 15 years, image-guided percutaneous ablation has been developed which allows to treat tumors with temperature modifications. These mini-invasive techniques may be r...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2013.1728
更新日期：2013-04-01 00:00:00
abstract：:The study bears on 672 infiltrating carcinomas of the cervix treated from 1977 until the end of 1991, by a radiosurgical combination (311 patients) or by exclusive irradiation (361 patients). The radiosurgical series includes mostly stages IB and II and patients under 50 years because of the therapeutic protocol. Most...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1995-07-01 00:00:00
abstract：:A multidisciplinary expert group had reviewed all scientific data available of post mastectomy pain syndrome. Seventy six publications were retained and thirty evidence based diagnosis, treatment and follow-up recommendations are listed. Few of theses recommendations are classed level A. Datas analysis make possible t...
journal_title：Bulletin du cancer
pub_type： 杂志文章,实务指引,评审
doi：
更新日期：2007-03-01 00:00:00
abstract：:Gemcitabine has demonstrated a good efficacy in number of tumor types. Thanks to its favourable toxicity profile, gemcitabine can be used in combination with a number of drugs. Single agent gemcitabine and gemcitabine-based combinations have been evaluated in metastatic breast cancer. Some of these combinations, such ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2002-08-01 00:00:00
abstract：:Cell signalling represents the network of cell communication pathways. Reception of a message by a cell results in the implementation of various direct and indirect actions, especially through the transcription of the genes required for carrying out the orders received. The signals exchanged by cells may concern proli...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2010.1199
更新日期：2010-11-01 00:00:00
abstract：:In part I of this article, we reviewed the general aspects of childhood brain tumors. In part II, we present the most common neoplasms and their treatment. The quality of the surgical resection appears to be of first importance in the prognosis. Progress in radiotherapy and chemotherapy have contributed to the improve...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1989-01-01 00:00:00
abstract：:The increasing complexity of present day medicine--with highly effective and yet risky treatments, individual and collective expectations, and evolving ideological and cultural landmarks--often gives rise to difficult ethical problems. Specific meetings are valuable for understanding such problems, acquiring the relev...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：:Two criteria are firstly used in the selection of new anticancer agents:--originality of the mechanism of action and significant experimental antitumor activity in an in vivo animal model. Murine tumors grafted in syngenic mice and human tumor xenografts implanted in nude mice are old models which continue to be widel...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：:Should we consider surgery for pancreatic cancer when resectability seems initially uncertain? The answer is no consensual as illustrated by the controversy presented here. This article presents the key arguments against surgery. ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/S0007-4551(15)31231-5
更新日期：2015-06-01 00:00:00
abstract：:Apparition of new tools in the therapy of multiple (MM) strengthens the need for valuable prognostic categorization of each patient in order to propose the most adequate treatment. Prognostic factors in MM can be divided in four groups. The first, including beta 2 microglobulin (beta 2m), hemopoiesis impairment, osteo...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：INTRODUCTION:Adapted physical activity (APA) is recognized as an effective supportive care for asthenia and quality of life in oncology. Before an APA program was organized, the feasibility of such a program was evaluated among the patients. METHODS:Descriptive, prospective, semi-qualitative, single-center study over ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/j.bulcan.2017.11.011
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:The standard treatment in first line of advanced or metastatic urothelial bladder cancer (MBC) is the association of Gemcitabine and Cisplatin (GC). Avelumab, an anti-PD-L1 agent, has recently demonstrated efficacy. The objective is to evaluate the combination of these 3 agents. METHODS:This phase II random...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/S0007-4551(20)30280-0
更新日期：2020-06-01 00:00:00
abstract：:Between 1959 and 1974, two hundred and ninety six carcinomas of the nasopharynx were seen at the Institut Gustave-Roussy, in adults. 78% were in man. The most frequently encountered were undifferentiated or poorly differentiated forms, 76% of cases. 38% only of the patients had their birthplace in France. On the first...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1975-07-01 00:00:00
