Abstract:
:The relationships involved in host resistance to tumor development were studied. Animals were pretreated by local hyperthermia, local irradiation and combined local hyperthermia and x-irradiation. After treatment, the animals were inoculated with tumor cells 0--96 or 0--120 hours post treatment. (BALB/c X C57B1/6)F1 mice were inoculated with the SV40 local fibrosarcoma, and (C3H/eB/B1)F1 mice were inoculated with the metastatic Lewis lung carcinoma. The results show an enhanced resistance to tumor development in animals pretreated by the combined simultaneous local heat and x-irradiation, as compared to animals only preirradiated, only preheated, or to control untreated tumor-bearing animals.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Yerushalmi Asubject
Has Abstractpub_date
1978-01-01 00:00:00pages
475-8issue
4eissn
0007-4551issn
1769-6917journal_volume
65pub_type
杂志文章abstract::Endometrial cancer is a common cancer in older women and is often associated with comorbidities. Management of metastatic disease and/or relapse requires a multidisciplinary approach. Recent advances in the understanding of oncogenesis and molecular classification of endometrial cancers offer new therapeutic perspecti...
journal_title:Bulletin du cancer
pub_type: 杂志文章,实务指引
doi:10.1016/j.bulcan.2020.06.006
更新日期:2020-10-01 00:00:00
abstract::THE ROLE OF RUXOLITINIB IN THE TREATMENT OF MYELOPROLIFERATIVE NEOPLASMS: The discovery of the JAK2V617F mutation in 2005, present in 95% of polycythemia vera (PV) and in 55% of myelofibrosis (MF) patients, opened the way for a new era of targeted therapies for myeloproliferative neoplasms. Ruxolitinib was the first-i...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/S0007-4551(16)30143-6
更新日期:2016-06-01 00:00:00
abstract::The retrospective evaluation of the dose after an irradiation accident is of paramount importance; it allows an adequate selection of patients and the most appropriate treatment can then be proposed. Classical physical dosimetry often lacks precision for dose assessment in such accidents. Cytogenetics, usually more re...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION:Oral anticancer drugs have raised the question of how to follow-up these patients and how to coordinate this follow-up. The CHIMORAL study evaluated the involvement of primary care providers and a coordination by territorial health networks. Training/information tools were provided, as well as weekly nursi...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2020.08.014
更新日期:2020-12-01 00:00:00
abstract::This survey, conducted in region Rhône-Alpes (France), aims to assess some data in thoracic oncology practice including availability of specialized equipments. This study is based on a questionnaire mailed to oncologists and pulmonologists in the region. Of 401 questionnaires, the response rate was 56%. Responses of 7...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2011.1366
更新日期:2011-06-09 00:00:00
abstract::Gangliosides are glycosphingolipids which contain neuraminic acid. Although they are present in the plasma membranes of all cells, gangliosides are expressed differently, both quantitatively and qualitatively, in certain types of cancer. Modifications in ganglioside composition may account for some of the abnormal int...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract::The considerable progress of molecular biology within the past twenty years has permitted a more and more detailed characterization of the molecular mechanisms regulating cell proliferation. The corollary to these discoveries has been the identification of different deregulations yielding to cell transformation and ca...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-04-01 00:00:00
abstract:INTRODUCTION:Systematic metastasis staging in early breast cancer is no longer recommended. However, it is still performed before adjuvant chemotherapy. MATERIALS AND METHODS:We assessed metastasis screening of asymptomatic women with a local breast cancer without lymph node involvement when adjuvant chemotherapy was ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2015.02.018
更新日期:2015-05-01 00:00:00
abstract::Chemotherapy has dramatically improved the prognosis of non-seminomatous germ cell tumors (NSGCT). However, some patients relapse and others are refractory to first line chemotherapy. We studied a salvage chemotherapeutic regimen with etoposide 75 gm/m2/day, and cisplatin 40 mg/m2/day, days 1-5 and Ifosfamide 3 g/m2/d...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND AND AIM:CABYR, a calcium-binding tyrosine phosphorylation regulated fibrous sheath protein, was initially reported to be testis-specific and subsequently shown to be present in brain tumors, pancreas cancer and lung cancer. This study aimed to investigate the expression and effects of the CABYR-c transcript ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2011.1538
更新日期:2012-03-01 00:00:00
abstract::Does radical mastectomy for cancer remain needed? Breast conserving treatment may be achieved by surgery, primary chemotherapy followed by radiotherapy and surgery. This article attempts at defining (according to clinical and pathological parameters of the tumor and patient's characteristics), when conservative treatm...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::For most diseases, one observes great variability in clinical course and response to therapy which should be taken into account in the design and the analysis of clinical trials. Eligibility criteria and stratified randomization use prognostic knowledge. A suitable analysis of randomized studies includes: (1) checking...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Between november 1993 and october 1996, a cervical screening program was proposed for women 25-65-year-old who tend to have little or no medical supervision, in three suburban districts of Lyon. The data and results of the two last Pap-smears have been collected together with details of gynecological follow-up. Both g...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::Two criteria are firstly used in the selection of new anticancer agents:--originality of the mechanism of action and significant experimental antitumor activity in an in vivo animal model. Murine tumors grafted in syngenic mice and human tumor xenografts implanted in nude mice are old models which continue to be widel...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::Adjuvant chemotherapy after apparently complete resection of gastrointestinal cancer may be theoretically justified by the high rate of local and metastatic recurrences. However, the results of controlled trials are generally disappointing, even if some of them have recently suggested some hope, chiefly for adjuvant t...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Oncotype DX® has been validated as quantifying the likelihood of distant recurrence at 10 years and overall chemotherapy benefit in patients with estrogen-receptor-positive and HER-2-negative early breast cancer. In 2012, this genomic signature was routinely available for patients in Franche-Comté, France. Patients el...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2014.1923
更新日期:2014-07-01 00:00:00
abstract::The French Northern Oncology Group carried out a randomised, cross-over study comparing two anti-emetic treatment strategies in 150 chemotherapy-naive patients, receiving their first two courses of moderately-emetogenic drugs. Nausea and vomiting were assessed using a self-administered questionnaire for five days. Ant...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-12-01 00:00:00
abstract::The treatment of chronic myeloid leukemia (CML) has considerably evolved since imatinib mesylate has been introduced as a new therapeutic weapon for this disease. The 5-year updated results of the IRIS study confirmed that imatinib mesylate is the best first line therapy for chronic phase CML with an overall survival ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2007-10-01 00:00:00
abstract::Oxaliplatin in combination with 5-fluorouracil/leucovorin (LV5FU) improves the response rate and survival of patients with metastatic colorectal cancer. The objective of the Mosaic study was to evaluate the efficacy of this association in the adjuvant treatment of stage II and III colon cancer. This international stud...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2006-02-01 00:00:00
abstract:INTRODUCTION:Adapted physical activity (APA) is recognized as an effective supportive care for asthenia and quality of life in oncology. Before an APA program was organized, the feasibility of such a program was evaluated among the patients. METHODS:Descriptive, prospective, semi-qualitative, single-center study over ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2017.11.011
更新日期:2018-03-01 00:00:00
abstract::Geriatric oncology represents a novel specialty which can be defined as specific older cancer patients management. It includes a validated geriatric procedure, the comprehensive geriatric assessment, which is the best way of approaching the complex interacting medical problems of frail older patients. Geriatric assess...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:CONTEXT:The "Standards, Options and Recommendations" (SOR) project, started in 1993, is a collaboration between the Federation of French Cancer Centers (FNCLCC), the 20 French Cancer Centers, and specialists from French Public Universities, General Hospitals and Private Clinics. The main objective is the development of...
journal_title:Bulletin du cancer
pub_type: 指南,杂志文章,实务指引
doi:
更新日期:2002-02-01 00:00:00
abstract::With 2 436 deaths in 1979, ovarian cancer is relatively infrequent in France comprising but 5 per cent of female mortality from malignant disease. However, the rate of increase in mortality is considerable, 70 per cent between 1955 and 1979 or 2,9 per cent per year, greater than that for female bladder and breast canc...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Combination of radiotherapy and androgen deprivation is now considered as the standard of care for patients with a localized prostate cancer but poor prognostic factors. Two groups of randomized trials have led to this recommendation. Some have compared radiotherapy alone versus hormonal treatment and radiotherapy: th...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2012.1567
更新日期:2012-07-01 00:00:00
abstract::In order to understand the kinetics of this experimental model, we studied the influence of age and sex on primary tumoral and pulmonary metastatic yields and on the growth kinetics parameters. Connective tissue tumors were induced by DMBA in male and female Swiss mice of various ages (pre and postpubertal, adult and ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Ten years after the discovery of the predictive value of KRAS status for anti-EGFR antibodies, other genes involved in oncogenesis and therapeutic responses were identified and are now systematically sought. Molecular diagnosis often requires invasive procedures, sometimes iatrogenic, and is limited by feasibility pro...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2015.10.017
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:The standard treatment in first line of advanced or metastatic urothelial bladder cancer (MBC) is the association of Gemcitabine and Cisplatin (GC). Avelumab, an anti-PD-L1 agent, has recently demonstrated efficacy. The objective is to evaluate the combination of these 3 agents. METHODS:This phase II random...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/S0007-4551(20)30280-0
更新日期:2020-06-01 00:00:00
abstract::As soon as they get accepted into medical school, students find themselves facing numerous expectations: coping with tremendous study burden, competing with others for the best rank, completing internships and participating in the race for publishing are only to name a few. This big juggle makes it hard for the medica...
journal_title:Bulletin du cancer
pub_type: 社论
doi:10.1016/j.bulcan.2018.04.005
更新日期:2018-06-01 00:00:00
abstract::Taxoids and platinum derivatives display a true activity against many types of solid tumors. Their relatively non overlapping toxicity profiles and their different mechanisms of action made their combination attractive. Actually, the frequency and the severity of the toxicity appeared schedule-dependent. Thus, cisplat...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2000-08-01 00:00:00
abstract::Pain is frequent in the course of cancer and can have negative consequences on patients quality of life. The great majority of patients can be helped by simple treatments. The prescription of morphine (M) must be preceded by some explanations. In order to verify the reality of these explanations, a study was done in a...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-04-01 00:00:00