Abstract:
:This paper reviewed the 2002 guidelines established by the National Federation of Cancer Centres. A group of experts nominated by the 3 French Societies involved in the treatment of cancer pain (AFSOS, SFAP, SFETD), established new guidelines ratios for morphine switching and/or changing of route of administration, in patients for whom either pain was not adequatly managed or adverse effects were unbearable. After a rapid reminder of the pharmacokinetics and metabolism properties of morphine, experts explained why the theory of opioid rotation (oxycodone, hydromorphone, fentanyl, methadone, tapentadol) using fixed equianalgesic ratios is not any more appropriate for a secure clinical practice. In the light of recent publications enhancing our knowledge on the efficacy of new drug switching ratios and for changing the route of administration of morphine, the group of experts recommended to use reconsidered switching ratios favoring security upon efficacy, to minimize overdosing and adverse effects. Consequently, after the new conversion ratio (using slow release opioids) was applied, a second titration should be done by means of normal release rescue formulations for breakthrough pain episodes. A smartphone App. OpioConvert® will be available for rapid and secure dose conversions.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Michenot N,Rostaing S,Baron L,Faure S,Jovenin N,Hubault P,Delorme T,Collin E,Filbet M,Chvetzoff G,Delorme C,Minello C,Magnet M,Ammar D,Krakowski I,Poulain Pdoi
10.1016/j.bulcan.2018.06.011subject
Has Abstractpub_date
2018-11-01 00:00:00pages
1052-1073issue
11eissn
0007-4551issn
1769-6917pii
S0007-4551(18)30225-Xjournal_volume
105pub_type
杂志文章,实务指引,评审abstract::Urothelial tumors are very rare in children (to date, only about 150 cases have been reported worlwide). Only 20% occur before the age of ten. The aim of this study is to specify the clinicopathologic features of urothelial tumor in young patients, which require a slightly different approach to treatment. On the basis...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2016.11.018
更新日期:2017-02-01 00:00:00
abstract::According to the point 7.6 and 7.7 of the Cancer Plan 2014, all cancer patients should have access to supportive care. Indeed, the supportive care consultation in oncology is an important tool for the symptom management of cancer patients at all times of treatment. This consultation can be mono-disciplinary or multi-d...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2015.04.019
更新日期:2015-09-01 00:00:00
abstract::Theoretical teaching of oncology was improved, 15 years ago, by individualizing a special university course during medical studies in France. However medical students need also practical exercising by relation with cancer patients. The main goals may be defined and given to students at the beginning of practical cours...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Cancerogenesis is believed to be a multistep process composed of different alterations that drive the transformation of normal human cells into highly malignant derivatives. These changes include self-sufficiency in growth signals, insensitivity to growth-inhibitory signals, the evasion of programmed cell death, a lim...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2008.0600
更新日期:2008-03-01 00:00:00
abstract::The evaluation of the risk-benefit balance in public health is an ethical commitment, based on the imperative of not harming people. Screening is a probabilistic approach, which, in order to serve the needs of a few, involves the largest number to share the potential harmful effects. Improvement of scientific knowledg...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2018.04.008
更新日期:2019-01-01 00:00:00
abstract::Angiogenin is one of the most potent inducers of neovascularization in experimental models in vivo. Angiogenin is normally present in plasma but overexpressed in cancer patients. The possible involvement of angiogenin in the development of cancer is suggested by its overexpression in patients with a variety of tumours...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-08-01 00:00:00
abstract::The discovery of oncogenes and tumor suppressors has established the original concept of cancer development based on a cascade of spontaneously occurring somatic mutations. It is now well known that genomes of cancer cells are deeply rearranged and that these rearrangements have devastating consequences on their organ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2010.1200
更新日期:2010-11-01 00:00:00
abstract::In order to understand the kinetics of this experimental model, we studied the influence of age and sex on primary tumoral and pulmonary metastatic yields and on the growth kinetics parameters. Connective tissue tumors were induced by DMBA in male and female Swiss mice of various ages (pre and postpubertal, adult and ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::From 1970 to 1982, 79 cases of nasopharyngeal carcinomas were treated at the Regional Cancer Center of Lille (France). At the term of the study, it appears that patients of Central Europe origin have a rather high risk of NPC (17% of cases, that ethnic population representing about 8% of all superior aerodigestive tra...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::We report on a case of 5-fluorouracil induced neurotoxicity during 5-fluorouracil cisplatin combination chemotherapy for advanced head and neck squamous cell carcinoma. The initial manifestations included an acute cerebellar syndrome and peripheral neuropathy. Computed tomography of the brain was normal. The results o...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The radiobiological properties of the hadrons (neutrons, protons, carbon ions) led to their therapeutic use in sarcomas, as a referent therapy or as an alternative to photon therapy. An extensive review of the literature has been conducted to assess the present indications and the perspectives for hadrontherapy. Compa...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2010.1125
更新日期:2010-06-01 00:00:00
abstract::From a series of 89 clinically inflammatory breast cancers, the authors settle a subgroup of tumors, the infiltrative ductal carcinomas with a pleomorphic structure. They have better histological and hormonal prognostic criteria than the other carcinomas, especially the infiltrative ductal carcinomas with an atypical ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Breast cancer remains a potentially lethal disease, which requires aggressive treatments and is associated with long-term consequences. Its prognosis is linked to both tumor biology and burden at diagnosis. Although treatments have allowed important improvements in prognosis over the past 20 years, breast cancer scree...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2016.06.005
更新日期:2016-09-01 00:00:00
abstract::Despite great improvements in the outcome of patients with lymphoma, some may still relapse or present with primary refractory disease. In these situations, allogeneic hematopoietic cell transplantation is a potentially curative option, this is true particularly in the case of after autologous stem cell transplantatio...
journal_title:Bulletin du cancer
pub_type: 共识发展会议,杂志文章,实务指引,评审
doi:10.1016/j.bulcan.2017.10.018
更新日期:2017-12-01 00:00:00
abstract:INTRODUCTION:Since the last cancer plan 2014-2019, the assessment of the impact of the disease on caregivers became essential. The quality of caregiving represents an important part of the patient's quality of life. The main objective was to describe the evolution of caregiver's attachment style during the first three ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2020.08.011
更新日期:2020-11-01 00:00:00
abstract:INTRODUCTION:French national guidelines lead us to increase the part of one-day breast cancer conservative surgery. Our objective was to check if we can enhance our outpatient part and to identify solutions to improve our practices. METHODS:From 01/01/2013 to 31/12/2014, we conducted a monocentric and retrospective re...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2015.09.010
更新日期:2015-12-01 00:00:00
abstract::Infection of secondary mouse fibroblast cultures with human cytomegalovirus (HCMV) led to the production of viral antigens in the absence of detectable virus replication. Antigen production was not dependent on viral DNA synthesis since it was not inhibited by cytosine arabinoside. Beginning at 15 days post-infection,...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::Doxifluridine, a new fluorouracil analog with a low myelosuppressive effect, has recently been subject to various disease-oriented, Phase II trials. For the present evaluation of drug tolerance, the Phase II data of 114 patients having received 376 doxifluridine cycles has been used. The treatment cycles consisted of ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:UNLABELLED:This CORCAN study is concerned with the way patients hospitalised for peritoneal carcinosis perceive surgical treatment and hyperthermic intraperitoneal chemotherapy (HIPEC). OBJECTIVES:(1) To identify and analyse, using concepts of social representation and accounts of the illness, characteristics of the w...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2015.10.015
更新日期:2016-02-01 00:00:00
abstract::Advanced stage follicular lymphoma is incurable by conventional treatment. Important progress has been observed with the development of new therapies based on monoclonal antibodies and on the use of radioimmunotherapy (RIT) in the treatment of non-Hodgkin lymphomas (NHL). Rituximab in combination with chemotherapy in ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2007-09-01 00:00:00
abstract::Advances in medical imaging have greatly enhanced the speciality of radiation oncology by allowing more healthy tissue to be speared for better tumour coverage. Positron emission tomography (PET) with the glucose analogue [18F]-fluoro-2-deoxy-D-glucose (FDG) is a functional imaging method that has become widely used i...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2007-01-01 00:00:00
abstract::Chemoprevention is the use of natural or synthetic compounds in order to reverse, suppress or prevent the carcinogenic process. Among the many pathways dysregulated during the carcinogenic process, cyclooxygenase-2 (Cox2) seems to be one of the most promising pathways to target in order to achieve chemopreventive and ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2004-05-01 00:00:00
abstract::Ewing tumours are characterised as tumours consisting of small, blue, round malignant cells that may exhibit varying degrees of neural differentiation. Most of them arise in bony sites, and they represent the second commonest primary osseous malignancy in and adolescence and young adults. During the past 30 years, che...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2010.1120
更新日期:2010-06-01 00:00:00
abstract::The purpose of external beam radiotherapy is to sterilize malignant tumours and at the same time to avoid complications by radiation injury to the surrounding healthy tissues. Modern radiation techniques in recent years have allowed to safely escalate the dose by approximately 10% for the treatment of prostate cancer,...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2008.0599
更新日期:2008-03-01 00:00:00
abstract::UPDATED 2016 RECOMMENDATIONS FOR THE CLINICAL PRACTICE OF NICE/SAINT-PAUL-DE-VENCE IN OVARIAN CANCER AND ADVANCED CERVICAL CANCER: Since the first edition of the 2012-2013 Clinical Practice Recommendations Nice-Saint-Paul for gynecological cancers, the management of ovarian cancer has become more complex with a better...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/S0007-4551(17)30156-X
更新日期:2017-05-01 00:00:00
abstract::This article, devoted specifically to gynaecological cancers and their impact on the sexual and marital lives, is a collaboration between the psychologists and onco-gynaecologist within a cancer center. In oncology, gynaecological cancers' treatments involve at the same time anatomical, physiological and functional mo...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2015.02.008
更新日期:2015-05-01 00:00:00
abstract::Margin status in cervical pathology is one of most important predictive factor of recurrent disease. Even if management of surgical biopsy is standardized, quality of surgical procedure is fundamental. Frozen section can be realise in order to complete surgical procedure if margins are involved. Extemporaneous exam of...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2008.0756
更新日期:2008-12-01 00:00:00
abstract::Colorectal primary signet ring cell carcinoma (SRCC) is a rare entity accounting for nearly 1% of all colorectal carcinomas. It is an independent prognostic factor associated with less favorable outcome. This aggressiveness is mainly due to the intrinsic biology of these tumors. Here is an overview of the literature r...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2015.07.005
更新日期:2015-10-01 00:00:00
abstract::Leiomyosarcoma of the larynx is extremely rare, only 21 cases were reported in the literature. The authors report a personal case in a 26 years old patient treated by a total laryngectomy and analyse all cases of the literature. It comes in relative young man (42 years old) in regard to the others ORL localisations. T...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1996-10-01 00:00:00
abstract::The network of cancer care units in Lorraine area (Oncolor) developed management training for people working in chemotherapy units, and cytotoxic drug preparation. The programme was framed both for staff of executives (pharmacists), and technicians. Firstly, comparison between practices and theoretical recommendations...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00