[Carcinoma of the nasopharynx (cavum) : clinical and developmental aspects].

abstract：:Radiation oncologist often faced cancer pain, regardless the stage of cancer. Given the high prevalence of cancer pain, and its potential for profound adverse consequences, all patients with active malignancy should be routinely screened and treated for pain. Using a questionnaire developed by the pain center of the I...

journal_title：Bulletin du cancer

authors： Auberdiac P,Levy A,Guy JB,Malkoun N,Moncharmont C,Chargari C,Michaud P,De Laroche G,Magné N

更新日期：2012-09-01 00:00:00

abstract：:The treatment of the advanced ovarian adenocarcinoma, most frequently stage at diagnostic, relies on association of surgery and chemotherapy. The current standard is the association carboplatine-paclitaxel. In spite of this treatment, relapses are frequent, and the prognosis thus remains very reserved. Presently the c...

journal_title：Bulletin du cancer

authors： Lhommé C,Even C,Morice P,Balleyguier C,Petrella M,Gouy S,Uzan C,Duvillard P,Pautier P

更新日期：2009-12-01 00:00:00

abstract：:Despite development and widespread of PSA, current tools evaluating prostate cancer still give inconsistent or insufficiently relevant results. As encouraging data raised from circulating tumor cells detection in colon or breast cancer, they were evaluated as a surrogate prostate cancer biomarker. Tumor cells need to ...

journal_title：Bulletin du cancer

authors： Murez T,Droupy S,Rebillard X,Alix-Panabieres C

更新日期：2012-07-01 00:00:00

abstract：:Seventy five human breast cancers were examined in order to search for the presence of thymidine kinase of the fetal-type (TK-F). The presence of TK-F was evidenced in all tumors. Its activity varied from one to another tumor, but it was evident that the increased TK activity observed in mammary cancers could exclusiv...

journal_title：Bulletin du cancer

authors： Javre JL,Hannouche N,Samperez S,Jouan P

更新日期：1986-01-01 00:00:00

abstract：:Colorectal cancer (CRC) is the second leading cause of cancer-related mortality in France. Recently, colorectal cancer subtyping consortium (CRCSC) identified 4 consensus molecular subtypes (CMS). CMS1 is enriched for CRC with deficient DNA mismatch repair system (dMMR) and tumors with mutated BRAF. Intriguingly, CMS1...

journal_title：Bulletin du cancer

authors： Cohen R,Cervera P,Svrcek M,Dumont C,Garcia ML,Chibaudel B,de Gramont A,Pocard M,Duval A,Fléjou JF,André T

更新日期：2015-06-01 00:00:00

abstract：:The authors analyze the respiratory sequelae in 19 patients with limited small cell lung carcinoma who survived for more than 30 months following an alternating chemo-radiotherapeutic combined regimen. The clinical tolerance measured with respiratory functional test is acceptable. In two patients an effort dyspnea is ...

journal_title：Bulletin du cancer

authors： de Cremoux H,Baldeyrou P,Martin M,Ruffié P,Arriagada R,Le Chevalier T

更新日期：1987-01-01 00:00:00

abstract：:Distinct clinicopathologic acute lymphoblastic leukemia (ALL) entities have been identified, resulting in the adoption of risk-oriented treatment approaches. In Philadelphia chromosome-positive (Ph(+)) ALL, the optimal treatment requires the addition of BCR-ABL tyrosine kinase inhibitors, as imatinib. However, the out...

journal_title：Bulletin du cancer

authors： Thomas X

更新日期：2011-07-01 00:00:00

abstract：:To have a better understanding of the poor participation rate among general practitioners (GPs) in cervical cancer screening, we have conducted a survey in the department of Bas-Rhin on a small sample of GPs. This helped to explain how they perceived this technical act, the problems or barriers related to it: rate, fu...

journal_title：Bulletin du cancer

authors： Weil O,Schaffer P

更新日期：1994-04-01 00:00:00

abstract：INTRODUCTION:Genetic predisposition to familial hematological malignancies was previously described through several epidemiological analyses, but the genetic basis remains unclear. The tumor-suppressor ARLTS1 gene was previously described in sporadic hematological malignancies and familial cancer context. METHODS:In t...

journal_title：Bulletin du cancer

authors： Hamadou WS,Besbes S,Mani R,Bourdon V,Ben Youssef Y,Achour B,Regaieg H,Eisinger F,Mari V,Gesta P,Dreyfus H,Bonadona V,Dugast C,Zattara H,Faivre L,Noguchi T,Khélif A,Sobol H,Soua Z

更新日期：2017-02-01 00:00:00

abstract：:This article briefly outlines three major biochemical problems in relation to the presence of chemical carcinogens in mammalian cells: (a) the enzymatic systems responsible for the chemical carcinogen metabolism; (b) the nature of the reactive metabolites and (c) the cellular target(s). References and examples are onl...

journal_title：Bulletin du cancer

authors： Gielen JE

更新日期：1978-01-01 00:00:00

abstract：:The epidemiology of cancers is known in France through mortality data provided by Inserm and morbidity data obtained by French tumor registries. The purpose of this study was to compare the incidence of laryngeal cancers in 9 French departments and to give an estimate of this incidence for the whole of France, based o...

journal_title：Bulletin du cancer

authors： Peng J,Ménégoz F,Lesec'h JM,Remontet L,Grosclaude P,Buémi A,Guizard AV,Tretarre B,Danzon A,Velten M,Maarouf N,Jougla E,Launoy G,Dubreuil A

更新日期：2004-04-01 00:00:00

abstract：:Infectious complications associated with granulocytopenia during the treatment of poor risk or relapsed germ cell tumors were studied in order to assess the frequency, morbidity and characteristics of these complications. Thirty-three cases were investigated at the Institut Gustave-Roussy; 63 episodes of granulocytope...

journal_title：Bulletin du cancer

authors： Ribrag V,Droz JP,Kattan J,Andremont A

更新日期：1992-01-01 00:00:00

abstract：:Basal-like carcinomas represent 10 to 15% of invasive breast carcinomas and have been identified from gene expression studies. Morphologically, these tumors are undifferentiated histopronostic grade 3 carcinomas, identified in clinical practice according to their immunophenotype "triple zero" (estrogen, progesterone a...

journal_title：Bulletin du cancer

authors： Vincent-Salomon A,Macgrogan G,Charaffe-Jauffret E,Jacquemier J,Arnould L

更新日期：2010-03-01 00:00:00

abstract：:The psychological consequences of cancer are most frequently reactive and do not constitute a major psychiatric illness. Anxiety and depression are the two main psychological disorders which occur frequently but with variable intensity according to the type of disease, its course, as well as the individual and social ...

journal_title：Bulletin du cancer

authors： Zittoun R,Ruszniewski M

更新日期：1988-01-01 00:00:00

abstract：:Iatrogenic pain is a common problem for cancer patients, including those due to hospital internal transport. An original prospective study conducted in 2006 allowed risk factor identification, and from 2007, a pluri-annual progress plan was implemented. Its actions were systematically evaluated and all phases of trans...

journal_title：Bulletin du cancer

authors： Nebbak JM,Vignozzi A,Bussy C,Charleux D,Laplanche A,Mathivon D,Di Palma M

更新日期：2013-07-01 00:00:00

abstract：:Neoadjuvant chemoradiotherapy is considered at the present time as the standard treatment of most T3-4 rectal cancer. In France a combination of radiotherapy (45 Gy/5 weeks) with concurrent capecitabine (1,600 mg/m2) is the most popular protocol. Randomized trials try to optimize this approach using new cytotoxic drug...

journal_title：Bulletin du cancer

authors： Gérard JP,Francois E,Deustch E,Rostom Y,Douar N,Benezery K,Milano G

更新日期：2009-03-01 00:00:00

abstract：:Sequencing the human genome brings new tools for the individualisation of cancer chemotherapy, especially thanks to the identification of polymorphisms of genes involved in anticancer drug metabolism or activity (pharmacogenetics). A few functional polymorphisms have been known for a long time (thiopurine methyltransf...

journal_title：Bulletin du cancer

authors： Robert J,Le Morvan V

更新日期：2008-10-01 00:00:00

abstract：:If chemotherapy beyond the third line often gives sum clinical benefits, it is sometimes prescribed only to avoid telling bad news to patients. Palliative chemotherapy can lead to symptom reduction and greater health related quality-of-live, but longer survival is unlikely. Physician's questioning about chemotherapy c...

journal_title：Bulletin du cancer

authors： Bouleuc C,Chvetzoff G

更新日期：2009-09-01 00:00:00

abstract：INTRODUCTION:The treatment of chronic myeloid leukemia (CML) has been revolutionized by the advent of tyrosine kinase inhibitors. The results of the IRIS trial demonstrated the efficacy and long-term safety profile of Imatinib. The objective of our work is to report the results at 15 years of treatment of CML in chroni...

journal_title：Bulletin du cancer

authors： Dakkoune M,Qachouh M,Zoukal S,Hassoune S,Khoubila N,Cherkaoui S,Lamchahab M,Rachid M,Madani A,Quessar A

更新日期：2020-09-01 00:00:00

abstract：:Superficial bladder tumor defined as pTa, pT1 and pTis stage is one of the most common cancer disease in the world. Intravesical BCGtherapy represents the best treatment when combined with transurethral resection to prevent tumor recurrence or progression and to lengthen the interval between recurrence. The toxicity i...

journal_title：Bulletin du cancer

authors： Prapotnich D

更新日期：1998-02-01 00:00:00

abstract：:Robotic assisted surgery is a new field of developing program for many specialties. As to head and neck oncology, the new procedure potentially offers alternatives to conventional surgery with decreased morbidity. The aim of this article is a description of the state of the art via a review of the literature. We empha...

journal_title：Bulletin du cancer

authors： Mallet Y,Moriniere S,Ceruse P,El Bedoui S

更新日期：2010-01-01 00:00:00

abstract：:The evolution of a high grade glioblastoma of a patient undergoing radio-therapy has been analysed by considering a mathematical model which simulates the brain tumour growth within a two-dimensional domain defined by the brain and ventricles geometry. This simulated behaviour was compared with morphological data obta...

journal_title：Bulletin du cancer

authors： Tracqui P,Leitner F,Esteve F

更新日期：1995-12-01 00:00:00

abstract：:Patients wish to be fully informed about their health, but some information and its disclosure may pose special challenges depending on the severity of the illness. This prospective observational study investigates the content of information about the disease and treatment, as well as the process by which information ...

journal_title：Bulletin du cancer

authors： Marcoux I

更新日期：2012-02-01 00:00:00

abstract：:From a series of 89 clinically inflammatory breast cancers, the authors settle a subgroup of tumors, the infiltrative ductal carcinomas with a pleomorphic structure. They have better histological and hormonal prognostic criteria than the other carcinomas, especially the infiltrative ductal carcinomas with an atypical ...

journal_title：Bulletin du cancer

authors： Mauriac L,Wafflart J,Trojani M,Durand M

更新日期：1983-01-01 00:00:00

abstract：:Over the past decade, trastuzumab was the only available monoclonal anti-HER2 antibody for the treatment of HER2 positive breast and gastric cancer. Recently, pertuzumab added to docetaxel and trastuzumab showed dramatic overall survival improvement in first line treatment of HER2 positive metastatic breast cancer. Pe...

journal_title：Bulletin du cancer

authors： Barthélémy P,Leblanc J,Wendling F,Wissler MP,Bergerat JP

更新日期：2014-12-01 00:00:00

abstract：:Many complementary and alternatives medicines are offered to patients with cancer. Among them, herbal medicines have a substantial place. These plants are mainly used to reduce adverse effects of anticancer treatments and for specific anticancer properties. Our review shows that only few clinical data support medicina...

journal_title：Bulletin du cancer

authors： Huet M

更新日期：2013-05-01 00:00:00

abstract：:The evaluation of the risk-benefit balance in public health is an ethical commitment, based on the imperative of not harming people. Screening is a probabilistic approach, which, in order to serve the needs of a few, involves the largest number to share the potential harmful effects. Improvement of scientific knowledg...

journal_title：Bulletin du cancer

authors： Launoy G,Duchange N,Darquy S,Moutel G

更新日期：2019-01-01 00:00:00

abstract：:The first study evaluating directly by the referring physician the clinical impact of [18F]-FDG-PET on modification of patient's management was performed only recently in California by means of a questionnaire. We have used the same methodology to evaluate this clinical impact during the opening year of our PET centre...

journal_title：Bulletin du cancer

authors： Talbot JN,Rain JD,Meignan M,Askienazy S,Grall Y,Bok B,Misset JL

更新日期：2002-03-01 00:00:00

abstract：:Tamoxifen is widely used nowadays in the management of breast cancer, having established its efficacy in this indication, especially for postmenopausal patients with ER-positive breast tumours. However, tamoxifen has recently been recognized as carcinogenic for the human endometrium, probably with an effect of duratio...

journal_title：Bulletin du cancer

authors： Sasco AJ,Ah-Song R,Gendre I,Zlatoff P,Bobin JY,Hallonet P,Leduc B

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Depression is an important symptom for many palliative care patients but is rarely identified. It's known to reduce quality of life and impact on palliation of physical symptom. These physical symptoms can be improved by an adequate treatment of depression. Many depressed cancer patients are not treated due ...

journal_title：Bulletin du cancer

authors： Rhondali W,Perceau E,Saltel P,Girard R,Filbet M

更新日期：2011-02-01 00:00:00