Abstract:
:The psychological consequences of cancer are most frequently reactive and do not constitute a major psychiatric illness. Anxiety and depression are the two main psychological disorders which occur frequently but with variable intensity according to the type of disease, its course, as well as the individual and social background of the patient. Physical factors such as digestive disorders, pain, mutilation and sterility can undermine the psychological adaptation. Cognitive impairment is generally due to neurological localizations of the disease or to metabolic abnormalities. The interrelationship between somatic and psychological factors must be carefully analyzed in order to recognize the determinants of suffering and abnormal coping or behavior.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Zittoun R,Ruszniewski Msubject
Has Abstractpub_date
1988-01-01 00:00:00pages
943-8issue
10eissn
0007-4551issn
1769-6917journal_volume
75pub_type
杂志文章abstract:INTRODUCTION:Breast cancer of young women has medico-psychological issues, particularly in the perspective of "after cancer" period. The objective of the study was to analyze the changes in management, in a decade including the publication of Cancer Plans I and II. METHODS:This retrospective unicentric study involved ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/S0007-4551(20)30049-7
更新日期:2019-12-01 00:00:00
abstract::We report on a case of 5-fluorouracil induced neurotoxicity during 5-fluorouracil cisplatin combination chemotherapy for advanced head and neck squamous cell carcinoma. The initial manifestations included an acute cerebellar syndrome and peripheral neuropathy. Computed tomography of the brain was normal. The results o...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The dependency between the risk of death and age is analysed, and the contribution of cancer to the overall risk of death is evaluated as a function of age. The frequency of the different cancer sites is described in different age groups. Lastly cancer mortality trends are presented by age. The risk of death from canc...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2007.0531
更新日期:2008-05-28 00:00:00
abstract::The considerable progress of molecular biology within the past twenty years has permitted a more and more detailed characterization of the molecular mechanisms regulating cell proliferation. The corollary to these discoveries has been the identification of different deregulations yielding to cell transformation and ca...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-04-01 00:00:00
abstract:INTRODUCTION:French national guidelines lead us to increase the part of one-day breast cancer conservative surgery. Our objective was to check if we can enhance our outpatient part and to identify solutions to improve our practices. METHODS:From 01/01/2013 to 31/12/2014, we conducted a monocentric and retrospective re...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2015.09.010
更新日期:2015-12-01 00:00:00
abstract::A retrospective review was made of 1 400 cases of cancer of the esophagus treated at the Centre "Francois Baclesse" between 1964 and 1975. The disease appeared at an earlier age and more frequently in men (95%) than in women. The lesions were located predominantly in the middle third of the esophagus. There was a high...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::Ataxia telangiectasia (AT) is a hereditary disease transmitted in a recessive mode and characterized by chromosomal instability and radiosensitivity. AT patients have a 100-fold higher risk of cancer than the general population. Although AT is a rare disease of which the frequency has been estimated to be 1/40,000, th...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::The first study evaluating directly by the referring physician the clinical impact of [18F]-FDG-PET on modification of patient's management was performed only recently in California by means of a questionnaire. We have used the same methodology to evaluate this clinical impact during the opening year of our PET centre...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::THE ROLE OF RUXOLITINIB IN THE TREATMENT OF MYELOPROLIFERATIVE NEOPLASMS: The discovery of the JAK2V617F mutation in 2005, present in 95% of polycythemia vera (PV) and in 55% of myelofibrosis (MF) patients, opened the way for a new era of targeted therapies for myeloproliferative neoplasms. Ruxolitinib was the first-i...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/S0007-4551(16)30143-6
更新日期:2016-06-01 00:00:00
abstract:FOCAL TREATMENT AND SYSTEMIC THERAPY IN METASTATIC KIDNEY CANCER:COMPLEMENTARY APPROACHES: To treat metastatic renal cell carcinoma, therapies used are with an oral intake, for the vast majority, and have many side effects that may compromise observance. Strategies of drug holiday have been studied and, in case of an i...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/S0007-4551(18)30376-X
更新日期:2018-12-01 00:00:00
abstract::The oncornaviruses share several biological, biochemical, and structural properties that distinguish them from other RNA viruses. Rous sarcoma virus, a representative of avian oncornaviruses, manifests two major functions: cell transformation and virus replication. Both functions are independent, and are expressed sep...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract::CAR T-cells are autologous or allogeneic human lymphocytes that are genetically engineered to express a chimeric antigen receptor targeting an antigen expressed on tumor cells such as CD19. CAR T-cells represent a new class of medicinal products, and belong to the broad category of Advanced Therapy Medicinal Products ...
journal_title:Bulletin du cancer
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1016/j.bulcan.2017.10.017
更新日期:2017-12-01 00:00:00
abstract::Alveolar soft part sarcoma, ASPS, is a rare malignant tumor, with preferential primary localization in limbs, usually occurring in adolescents and young adults. This sarcoma, well defined histologically and at molecular level, has an indolent course, but a high potential metastatic pulmonary and cerebral evolution, so...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2015.05.004
更新日期:2015-09-01 00:00:00
abstract::When cells are exposed to ionizing radiation, they initiate a complex response that includes the arrest of cell cycle progression in G1 and G2, apoptosis and DNA repair. DNA is an important subcellular target of ionizing radiation, but oxydative damage to plasma membrane lipids initiates signal transduction pathways t...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1999-04-01 00:00:00
abstract::The treatment of chronic myeloid leukemia (CML) has considerably evolved since imatinib mesylate has been introduced as a new therapeutic weapon for this disease. The 5-year updated results of the IRIS study confirmed that imatinib mesylate is the best first line therapy for chronic phase CML with an overall survival ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2007-10-01 00:00:00
abstract::Chemotherapy has dramatically improved the prognosis of non-seminomatous germ cell tumors (NSGCT). However, some patients relapse and others are refractory to first line chemotherapy. We studied a salvage chemotherapeutic regimen with etoposide 75 gm/m2/day, and cisplatin 40 mg/m2/day, days 1-5 and Ifosfamide 3 g/m2/d...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Death still occurs in Hodgkin's disease (HD) patients with advanced stages, but also in early stages. Therefore, the identification of the population of HD patients who would best benefit from an intensification of treatment is a prerequisite in all stages. The best known prognostic factors are bulky mediastinum, B sy...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::BRCA is a tumor suppressor gene implicated in the major mechanisms of cellular stability in every type of cell. Its mutations are described in numerous cancers, mainly breast and ovarian in women. It was also found an increase of lifetime risk of pancreas, colon, prostate cancer or lymphoma in men carriers. We report ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2014.1952
更新日期:2014-09-01 00:00:00
abstract::Diagnosis of brain metastases should aim to identify anatomoclinical entities for which a specific treatment is more accurate. Growing numbers of targeted therapies have shown to be effective against specific cancers. Several studies have reported that targeted therapies are capable of reducing brain metastases in mel...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2012.1677
更新日期:2013-01-01 00:00:00
abstract::In the French administrative "departement" of Côte-d'Or, between 1982 and 1990, the crude incidence rate and the age-adjusted world standardised incidence rate (ASR) for corpus uteri cancer were respectively 16.0 +/- 0.8 and 10.7 +/- 0.6 per 100,000 women per year. The incidence increased after 50 years of age, reachi...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1994-08-01 00:00:00
abstract::Since 1976 to 1978 inclusive, 465 patients with primary breast cancers underwent whole body analogical scintiscans, 456 numerical scans, and 453 were X-rayed. Ninety per cent received axillary node ablation, 62% presented adenopathies of which a third were capsular ruptures and 54% were T3 and T4. In 53 patients, the ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::With over 70,000 patients treated worldwide, protontherapy has an evolution on their clinical applications and technological developments. The ballistic advantage of the Bragg peak gives the possibility of getting a high conformation of the dose distribution to the target volume. Protontherapy has accumulated a consid...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2010.1149
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To assess the feasibility and efficacy of cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) without adjuvant chemotherapy for relapsed or persistent advanced ovarian cancer. METHODS:This observational study included stage IIIC ovarian cancer patients due to undergo CRS...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2010.1063
更新日期:2010-04-01 00:00:00
abstract::The evaluation of the risk-benefit balance in public health is an ethical commitment, based on the imperative of not harming people. Screening is a probabilistic approach, which, in order to serve the needs of a few, involves the largest number to share the potential harmful effects. Improvement of scientific knowledg...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2018.04.008
更新日期:2019-01-01 00:00:00
abstract::Radiation therapy may have deleterious effects on female fertility. It can cause ovarian dysfunction, uterine damages or disrupt the hypothalamic-pituitary axis. These effects occur at varying dose levels usually relatively low compared to the prescribed doses. Other co-factors influence the effects of radiation thera...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2015.03.015
更新日期:2015-05-01 00:00:00
abstract::The great majority of breast cancer cases are not associated with a mutated gene of high penetrance such as BRCA1, BRCA2 and TP53. Genes of low penetrance, frequently mutated in the general population, might play an important role in breast cancer development. The ATM gene, which encodes the ATM protein, mutated in th...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2001-07-01 00:00:00
abstract::Estrogen receptors (ER) were investigated using immunohistochemical techniques in 54 cases and biochemical techniques in 38 cases on a series of biopsy specimens of normal, hyperplasic and malignant mammary tissue (intraductal carcinoma). Immunohistochemical data were submitted to quantitative and semi-quantitative an...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::A better understanding of gliomas biology is now leading to a combined histo-molecular classification of these tumors. In anaplastic gliomas ongoing studies depend on 1p/19q codeletion status and in glioblastomas on MGMT methylation status. Advanced brain tumor imaging elicits a better identification of gliomas evolut...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2009.1019
更新日期:2010-01-01 00:00:00
abstract::Leiomyosarcoma of the larynx is extremely rare, only 21 cases were reported in the literature. The authors report a personal case in a 26 years old patient treated by a total laryngectomy and analyse all cases of the literature. It comes in relative young man (42 years old) in regard to the others ORL localisations. T...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1996-10-01 00:00:00
abstract::Stereotactic radiation therapy, consisting in irradiating the tumor with a high dose per fraction, has a therapeutic potential because of excellent local control. This technique requires a high accuracy level in order to minimize the risk of normal tissue toxicity. Initially used for cerebral localization, the stereot...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2010.1144
更新日期:2010-07-01 00:00:00