[Rational choice of a diagnostic test for the detection of bone metastases in breast cancer as a function of prevalence (based on the Bayes theorem)].

Abstract:

:Since 1976 to 1978 inclusive, 465 patients with primary breast cancers underwent whole body analogical scintiscans, 456 numerical scans, and 453 were X-rayed. Ninety per cent received axillary node ablation, 62% presented adenopathies of which a third were capsular ruptures and 54% were T3 and T4. In 53 patients, the presence of metastasis was estimated by clinical evaluation. In 38 patients, metastasis were confirmed. Probability for the patient to present metastasis when the test is positive, is: P (M/T +) = Se.p/(Se.p) + (1-p) + (1-p) (1-Spe) Probability when the test is negative is: P (M/T -) = p(1-Spe)/p(1-Se) + (1-p)Spe p = prevalence Se = sensibility Spe = specificity Performance of the test is the probability of obtaining a correct result is: P = (f1) - (f2) = (f3) The (f3) curves were plotted for each of the three tests. For a prevalence of 11% (clinical estimate) the X-ray or analogical scintiscans tests achieve the same performance, but that for a prevalence of 8% (exact number) the radiological examination yields the best. In two cases, numerical scan is better.

journal_name

Bull Cancer

journal_title

Bulletin du cancer

authors

Robillard J,Ly Van Hoa,Switzers O,Couette JE,Brune D

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

82-7

issue

1

eissn

0007-4551

issn

1769-6917

journal_volume

74

pub_type

杂志文章
  • [Prevention and treatment of antineoplastic drug-induced nausea and vomiting in pediatric onco-hematology: An update].

    abstract::Antineoplastic drug induced nausea and vomiting are common adverse events in cancer care of paediatric patients ; therefore, prevention and management of these adverse events is a major concern for healthcare professionals. There are common features between paediatric and adult patients in terms of the emetogenic leve...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2020.03.015

    authors: Delmotte M,Mouffak S,Mongaret C,Michelet-Huot E,Roques G,Slimano F

    更新日期:2020-01-01 00:00:00

  • Early diagnosis of gastrointestinal cancer.

    abstract::The earlier a gastro-intestinal cancer is treated the better will be the prospects of cure for the patient. It is therefore important to study the early clinical stages of the pathway which leads to the diagnosis of gastro-intestinal cancer in order to make this pathway short and quick. This paper identifies the delay...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Mac Adam DB

    更新日期:1980-01-01 00:00:00

  • [Primary non-Hodgkin's high grade malignant lymphoma of the digestive system. A prospective study of the combination of surgery-chemotherapy-radiotherapy].

    abstract::We report a prospective study concerning the association of surgery-chemotherapy and radiotherapy in the treatment of primary high grade digestive non-Hodgkin's lymphomas in 19 patients. The analysis of 11 stages IE, 5 stages II1E and 3 stages II2E allowed us to evaluate the efficacy and the tolerance of this triple t...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Renou P,Colombat P,Fetissof F,Calais G,Metman EH,Combe M,Dugay J,Martin JF,Linassier C,Lamagnere JP

    更新日期:1990-01-01 00:00:00

  • [Standards, Options and Recommendations: good practice for the management and shipment of histological and cytopathological cancer specimens].

    abstract:CONTEXT:The "Standards, Options and Recommendations" (SOR) collaborative project was initiated in 1993 by the Federation of the French Cancer Centres (FNCLCC), with the 20 French Regional Cancer Centres, several French public university and general hospitals, as well as private clinics and medical specialty societies. ...

    journal_title:Bulletin du cancer

    pub_type: 指南,杂志文章,实务指引

    doi:

    authors: Denoux Y,Blanc-Vincent MP,Simony-Lafontaine Jl,Verriele-Beurrier V,Briffod M,Voigt JJ

    更新日期:2002-04-01 00:00:00

  • [Gastrointestinal stromal tumours in pediatrics: a summary of the literature on this orphan disease].

    abstract::Recommendations for the management of gastrointestinal stromal tumours (GIST) in children and adolescents do presently not exist. Thus, a summary of the current literature was conducted serving as a basis for the development of optimal management strategies for childhood GIST. Pediatric cases of GIST may occur sporadi...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2010.1296

    authors: Verschuur A,André N,Blay JY

    更新日期:2011-01-01 00:00:00

  • [Unresolved questions in the indications for the conservative treatment of invasive cancer of the breast].

    abstract::The majority of patients with breast cancer can be treated by partial mastectomy and radiation therapy. The choice of the treatment involves the estimation of the risk for intramammary recurrence and the ability to achieve satisfactory cosmetic result. Patient selection in breast conserving therapy is dependent on cli...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Zinzindohoué C,Bobin JY

    更新日期:1998-09-01 00:00:00

  • [Treatment of locally extensive soft tissue sarcomas. Value of intra-arterial chemotherapy (author's transl)].

    abstract::Between 1964 and 1978, 21 patients with locally extensive soft tissue sarcoma received intal-arterial regional chemotherapy (IAC), combined with radiotherapy. Some patients were also submitted to conservative surgery. Although there were three serious accidents, one of which was lethal, the tolerance was considered ac...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Marée D,Bui NB,Chauvergne J,Avril A,Richaud P

    更新日期:1980-01-01 00:00:00

  • [Adjuvant treatment of colon cancer MOSAIC study's main results].

    abstract::Oxaliplatin in combination with 5-fluorouracil/leucovorin (LV5FU) improves the response rate and survival of patients with metastatic colorectal cancer. The objective of the Mosaic study was to evaluate the efficacy of this association in the adjuvant treatment of stage II and III colon cancer. This international stud...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: André T,Tournigand C,Achille E,Tubiana-Mathieu N,Lledo G,Raoul Y,Carola E,Flesch M,Muron T,Boutan-Laroze A,Guérin Meyer V,Boaziz C,Maigre M,Ganem G,Mousseau M,Mounedji-Boudiaf L,de Gramont A

    更新日期:2006-02-01 00:00:00

  • [Management of analgesics in cancer patients with renal impairment].

    abstract::Pain is frequent in cancer patients. To date, there is a consequent therapeutic arsenal so to manage pain; the different treatment strategies are the subject of various recommendations. Patients with cancer also frequently suffer from renal insufficiency, and this comorbidity may disrupt or jeopardize the analgesic st...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2011.1488

    authors: Rey JB,Tran T,Ammar D,Parent D,Janus N,Launay-Vacher V

    更新日期:2012-03-01 00:00:00

  • [Renal failure after allogeneic hematopoietic stem cell transplantation: Recommendations of the Francophone Society of Bone Marrow transplantation and cellular Therapy (SFGM-TC)].

    abstract::Acute and chronic renal failures are very common after allogeneic HSCT. These complications have a real impact on mortality and morbidity of transplant recipients. Within the framework of the ninth workshops of practice harmonization of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-...

    journal_title:Bulletin du cancer

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1016/j.bulcan.2019.05.002

    authors: Detrait M,de Berranger E,Dulery R,Ménard AL,Thépot S,Toprak SK,Turlure P,Yakoub-Agha I,Guillaume T

    更新日期:2020-01-01 00:00:00

  • [Image guided radiation therapy (IGRT)].

    abstract::Image guided radiation therapy (IGRT) is a major technical innovation of radiotherapy. It allows locating the tumor under the linear accelerator just before the irradiation, by direct visualization (3D mode soft tissue) or indirect visualization (2D mode and radio-opaque markers). The technical implementation of IGRT ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2010.1140

    authors: Lagrange JL,de Crevoisier R

    更新日期:2010-07-01 00:00:00

  • [Value of thymidine kinase in the prediction of response to treatment by chemotherapy or hormone therapy in breast cancer].

    abstract::Thymidine kinase (TK) was assayed in the cytosol of 210 primary breast cancers to assess its predictive value for response to first line chemotherapy and hormonotherapy. We performed correlations between TK and the other prognosis factors of breast cancer. TK activity is correlated with SBR grading and estrogen recept...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Bennini N,Mauriac L,Wafflart J,Bonichon F,Durand M

    更新日期:1992-01-01 00:00:00

  • [Statistical study of a series of 672 cases of carcinoma of the uterine cervix. Results and complications according to age and modalities of treatment].

    abstract::The study bears on 672 infiltrating carcinomas of the cervix treated from 1977 until the end of 1991, by a radiosurgical combination (311 patients) or by exclusive irradiation (361 patients). The radiosurgical series includes mostly stages IB and II and patients under 50 years because of the therapeutic protocol. Most...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Pernot M,Hoffstetter S,Peiffert D,Carolus JM,Guillemin F,Verhaeghe JL,Marchal C,Luporsi E,Beckendorf V,Stines J

    更新日期:1995-07-01 00:00:00

  • [Cervical cancer screening for high risk women: is it possible? Results of a cervical cancer screening program in three suburban districts of Lyon].

    abstract::Between november 1993 and october 1996, a cervical screening program was proposed for women 25-65-year-old who tend to have little or no medical supervision, in three suburban districts of Lyon. The data and results of the two last Pap-smears have been collected together with details of gynecological follow-up. Both g...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Mignotte H,Perol D,Fontanière B,Nachury LP,Blanc-Jouvand A,Fouillat V,Chauvin F,Lasset C

    更新日期:1999-06-01 00:00:00

  • [Gangliosides and cancer].

    abstract::Gangliosides are glycosphingolipids which contain neuraminic acid. Although they are present in the plasma membranes of all cells, gangliosides are expressed differently, both quantitatively and qualitatively, in certain types of cancer. Modifications in ganglioside composition may account for some of the abnormal int...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Dumontet C,Portoukalian J

    更新日期:1991-01-01 00:00:00

  • [Natural history of the cervical precancerous lesions (author's transl)].

    abstract::The histogenesis of precancerous lesions and of carcinoma in situ has undergone deep changes over the past ten years. In particular, concepts of re-epidermisation by indirect metaplasia has made it possible to understand the progressive process which results what are generally described as dysplasias. These lesions we...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: de Brux J

    更新日期:1979-01-01 00:00:00

  • [The impact of gynaecological cancers on woman's sexuality and her couple].

    abstract::This article, devoted specifically to gynaecological cancers and their impact on the sexual and marital lives, is a collaboration between the psychologists and onco-gynaecologist within a cancer center. In oncology, gynaecological cancers' treatments involve at the same time anatomical, physiological and functional mo...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1016/j.bulcan.2015.02.008

    authors: Vanlerenberghe E,Sedda AL,Ait-Kaci F

    更新日期:2015-05-01 00:00:00

  • [Colorectal cancer in the elderly].

    abstract::Colorectal cancer occurs after the age of 75 in 50% of the case, but elderly patients are under-treated and far from an optimal management of their disease. Principles of colorectal cancer management after the age of 75 are theoretically the same than for younger patients, but physiological age, comorbidities and pati...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2007.0545

    authors: Mitry E

    更新日期:2008-05-28 00:00:00

  • [Gliomas and BRCA genes mutations: fortuitous association or imputability?].

    abstract::BRCA is a tumor suppressor gene implicated in the major mechanisms of cellular stability in every type of cell. Its mutations are described in numerous cancers, mainly breast and ovarian in women. It was also found an increase of lifetime risk of pancreas, colon, prostate cancer or lymphoma in men carriers. We report ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2014.1952

    authors: Girardstein-Boccara L,Mari V,Met-Domestici M,Burel-Vandenbos F,Berthet P,Paquis P,Frenay MP,Lebrun-Frenay C

    更新日期:2014-09-01 00:00:00

  • [Translation and validation of Brief Edinburgh Depression Scale (BEDS) in French].

    abstract:BACKGROUND:Depression is an important symptom for many palliative care patients but is rarely identified. It's known to reduce quality of life and impact on palliation of physical symptom. These physical symptoms can be improved by an adequate treatment of depression. Many depressed cancer patients are not treated due ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2011.1310

    authors: Rhondali W,Perceau E,Saltel P,Girard R,Filbet M

    更新日期:2011-02-01 00:00:00

  • [Surgical treatment of carcinomas of the cervix stage III (author's transl)].

    abstract::This study is devoted to the analysis of the surgical treatment of cancer of the uterine cervix, stage III. Three circumstances are evaluated: - Stage III with urinary disease the purpose of the surgical treatment is most often to save the renal function;--Recurrences after radiotherapy where surgery is the only poss...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Rochard F,Michel G,Castaigne D,Lacour J

    更新日期:1980-01-01 00:00:00

  • [DNA form of the genome of oncornaviruses].

    abstract::The oncornaviruses share several biological, biochemical, and structural properties that distinguish them from other RNA viruses. Rous sarcoma virus, a representative of avian oncornaviruses, manifests two major functions: cell transformation and virus replication. Both functions are independent, and are expressed sep...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:

    authors: Hill M,Hillova J,Goubin G,Mariage R,Dantchev D

    更新日期:1975-04-01 00:00:00

  • [Understanding positon emission tomography (PET) with [18F]-FDG in clinical oncology. Informations dedicated to patients and relatives].

    abstract::In response to the evolution of the information-seeking behaviour of patients and concerns from health professionals regarding cancer patient information, the French National Federation of Comprehensive Cancer Centres (FNCLCC) introduced, in 1998, an information and education program dedicated to patients and relative...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,病人教育讲义

    doi:

    authors: Bourguet P,Brusco S,Corone C,Devillers A,Foehrenbach H,Lumbroso JD,Maszelin P,Montravers F,Moretti JL,Rain JD,Talbot JN,Carretier J,Leichtnam-Dugarin L,Delavigne V,Philip T,Fervers B,Fédération nationale des centres de lu

    更新日期:2005-07-01 00:00:00

  • [Allogeneic haematopoietic cell transplantation for diffuse large B cell lymphoma: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].

    abstract::Despite great improvements in the outcome of patients with lymphoma, some may still relapse or present with primary refractory disease. In these situations, allogeneic hematopoietic cell transplantation is a potentially curative option, this is true particularly in the case of after autologous stem cell transplantatio...

    journal_title:Bulletin du cancer

    pub_type: 共识发展会议,杂志文章,实务指引,评审

    doi:10.1016/j.bulcan.2017.10.018

    authors: Gauthier J,Chantepie S,Bouabdallah K,Jost E,Nguyen S,Gac AC,Damaj G,Duléry R,Michallet M,Delage J,Lewalle P,Morschhauser F,Salles G,Yakoub-Agha I,Cornillon J

    更新日期:2017-12-01 00:00:00

  • [Advances in adults' gliomas biology, imaging and treatment].

    abstract::A better understanding of gliomas biology is now leading to a combined histo-molecular classification of these tumors. In anaplastic gliomas ongoing studies depend on 1p/19q codeletion status and in glioblastomas on MGMT methylation status. Advanced brain tumor imaging elicits a better identification of gliomas evolut...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章,评审

    doi:10.1684/bdc.2009.1019

    authors: Ducray F,Dutertre G,Ricard D,Gontier E,Idbaih A,Massard C

    更新日期:2010-01-01 00:00:00

  • [Withholding and withdrawal decisions in oncology: legal frame and practice].

    abstract::Whereas medicine is progressing in illness treatment that used to be incurable, physicians are still faced with treatment failure. Hippocrates used to say: "primum non nocere" [1]. When the patient cannot expect benefit from potentially aggressive care, current or possible treatments have to be challenged to leave jus...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1684/bdc.2009.0910

    authors: Laude C,Deygas S

    更新日期:2009-07-01 00:00:00

  • A phase II trial of early intensive chemotherapy with autologous bone marrow transplantation in the treatment of poor prognosis non seminomatous germ cell tumors.

    abstract::Twenty-eight patients with poor prognosis, advanced metastatic non seminomatous germ cell tumors (NSGCT) were treated with early high dose chemotherapy and autologous bone marrow transplantation (ABMT) rescue. The primary tumor was testicular in 19 patients and extragonadal in nine patients. For 19 patients with a tes...

    journal_title:Bulletin du cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Droz JP,Pico JL,Ghosn M,Kramar A,Rey A,Ostronoff M,Baume D

    更新日期:1992-01-01 00:00:00

  • [Metastatic screening before adjuvant chemotherapy in breast cancer].

    abstract:INTRODUCTION:Systematic metastasis staging in early breast cancer is no longer recommended. However, it is still performed before adjuvant chemotherapy. MATERIALS AND METHODS:We assessed metastasis screening of asymptomatic women with a local breast cancer without lymph node involvement when adjuvant chemotherapy was ...

    journal_title:Bulletin du cancer

    pub_type: 杂志文章

    doi:10.1016/j.bulcan.2015.02.018

    authors: Thonnon C,Faure C,Chopin N,Beurrier F,Ho Quoc C,Tredan O,Carrabin N

    更新日期:2015-05-01 00:00:00

  • [Polymorphism in HLA and KIR genes and the impact on hematopoietic stem cell transplantation outcomes and unrelated donor selection: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].

    abstract::In an attempt to harmonize clinical practices among French hematopoietic stem cell transplantation centers, the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) held its sixth annual workshop series in September 2015 in Lille. This event brought together practitioners from across the c...

    journal_title:Bulletin du cancer

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1016/j.bulcan.2016.09.005

    authors: Dubois V,Brignier A,Elsermans V,Gagne K,Kennel A,Pedron B,Picard C,Ravinet A,Varlet P,Cesbron A,Delbos F,Yakoub-Agha I,Loiseau P

    更新日期:2016-11-01 00:00:00

  • Chemoresistance in the clinic: overview 1994.

    abstract::One of the most exciting areas in clinical oncology today is the translation of laboratory research in drug resistance into therapeutic tools to improve responses to antineoplastic drugs. Two areas of investigation are currently under study in both the laboratory and clinic: reversal of gluthathione-mediated resistanc...

    journal_title:Bulletin du cancer

    pub_type: 临床试验,杂志文章,评审

    doi:

    authors: Bates SE,Regis JI,Robey RW,Zhan Z,Scala S,Meadows BJ

    更新日期:1994-12-01 00:00:00