Abstract：
:Pain is frequent in cancer patients. To date, there is a consequent therapeutic arsenal so to manage pain; the different treatment strategies are the subject of various recommendations. Patients with cancer also frequently suffer from renal insufficiency, and this comorbidity may disrupt or jeopardize the analgesic strategy by changing the risk-benefit ratio of treatment options. This article provides recommendations for the use of drugs used for pain treatment after pointing out: 1) etiological and pathophysiological elements of pain; 2) therapeutic strategies for pain management; 3) data regarding renal failure in cancer and; 4) a point on drugs pharmacokinetics.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Rey JB,Tran T,Ammar D,Parent D,Janus N,Launay-Vacher Vdoi
10.1684/bdc.2011.1488subject
Has Abstractpub_date
2012-03-01 00:00:00pages
345-69issue
3eissn
0007-4551issn
1769-6917pii
S0007-4551(15)30483-5journal_volume
99pub_type
杂志文章,评审abstract：:To show the nature and magnitude of EKG anomalies subsequent to 5-fluorouracil (5FU) administration and determine whether the onset is dependent on a pre-existing cardiovascular pathological condition. 1,350 patients were treated by 5FU between 1995 and 2000. EKG were recorded in all patients before each administratio...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
abstract：:Sentinel lymph node (SLN) biopsy is fast becoming the standard for testing lymph node involvement in many institutions. However questions remain as to stage underestimation. The aim of this study was to analyse this specific risk in a retrospective study. Between 1975 to 1999, 1,636 patients underwent a breast cancer ...
journal_title：Bulletin du cancer
pub_type： 临床试验,杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：:Gemcitabine has demonstrated a good efficacy in number of tumor types. Thanks to its favourable toxicity profile, gemcitabine can be used in combination with a number of drugs. Single agent gemcitabine and gemcitabine-based combinations have been evaluated in metastatic breast cancer. Some of these combinations, such ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2002-08-01 00:00:00
abstract：:Chemoprevention is the use of natural or synthetic compounds in order to reverse, suppress or prevent the carcinogenic process. Among the many pathways dysregulated during the carcinogenic process, cyclooxygenase-2 (Cox2) seems to be one of the most promising pathways to target in order to achieve chemopreventive and ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2004-05-01 00:00:00
abstract：:Propensity score, an indicator of the propensity to get one treatment among two (or more), is encountered in non randomized studies (prospective or retrospective). It is calculated after the research of predictive factors for treatment attribution, and corresponds to the probability to receive one of the treatments co...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：:Fifty-one patients with non-Hodgkin's lymphoma refractory or relapsing after CHOP-like regimen, underwent a salvage chemotherapy by VPH: etoposide 100 mg/m2/d, D1 to D3, cisplatin 20 mg/m2/d, D1 to D5, ifosfamide 1 g/m2/d D1 to D5, mesna 1.2 g/m2/d D1 to D5, every 4 weeks. Among 46 evaluable patients for efficacy, 21 ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：SURGICAL DE-ESCALATION FOR INVASIVE BREAST CANCER TREATMENT:A surgical therapeutic de-escalation is going to continue but necessarily has to design in a progressive careful way and especially arranged with the other practitioners and therapeutic methods. These strategies concern as well the surgery of the breast as tha...
journal_title：Bulletin du cancer
pub_type： 社论
doi：10.1016/S0007-4551(16)30151-5
更新日期：2016-06-01 00:00:00
abstract：:Between 1964 and 1978, 21 patients with locally extensive soft tissue sarcoma received intal-arterial regional chemotherapy (IAC), combined with radiotherapy. Some patients were also submitted to conservative surgery. Although there were three serious accidents, one of which was lethal, the tolerance was considered ac...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Two hundred and twenty-three patients with disseminated breast cancer entered in a randomized trial: Group I: 130 patients were given a monthly 5 day- course of a cytotoxic chemotherapy protocol including Adriamycine, Vincristine, Cyclophosphamide, 5 Fluoro-uracile (A.V.L.F.); Group II: 93 patients were given alternat...
journal_title：Bulletin du cancer
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1984-01-01 00:00:00
abstract：:Bisphosphonates are potent osteoclastic inhibitors that are indicated in the prevention of bone complications. They could also be of interest in the prevention of bone metastases. Several recent international publications have highlighted the onset of osteonecrosis of the jaw (ONJ) in patients treated with bisphosphon...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2008.0617
更新日期：2008-04-01 00:00:00
abstract：:With over 70,000 patients treated worldwide, protontherapy has an evolution on their clinical applications and technological developments. The ballistic advantage of the Bragg peak gives the possibility of getting a high conformation of the dose distribution to the target volume. Protontherapy has accumulated a consid...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2010.1149
更新日期：2010-07-01 00:00:00
abstract：:Since the 1980's, women treated for breast cancer are reporting moderate cognitive impairments during and after chemotherapy. These cognitive impairments may be related to chemotherapy but also to hormone therapy, psychological distress, fatigue... This work is a critical review of the literature, which reports types ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2008.0818
更新日期：2009-02-01 00:00:00
abstract：:The presence of hypoxic regions within solid tumours is associated with a more malignant tumour phenotype and worse prognosis. To obtain a blood supply and protect against cellular damage and death, oxygen-deprived cells in tumours alter gene expression, resulting in resistance to therapy. Hypoxia is sensed at the cel...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：:The most recent cancer mortality and morbidity data available for France are presented. In 1999, cancers are the first cause of death among men (87,000 deaths) and the second most common among women (57,000 deaths) after cardiovascular diseases. Lung cancer is the most common cause of cancer death (21,000) in the male...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Immunotherapy alone or in combination with chemotherapy is now an integral part of the treatment of metastatic NSCLC. This treatment is transforming the management of these cancers, with 20-30% of patients achieving long survival. However, disease progression under treatment is still the rule for the majority of patie...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1016/j.bulcan.2020.04.018
更新日期：2020-01-01 00:00:00
abstract：:Metastases are responsible for the majority of deaths from solid cancers. Metastatic phenomenon, complex, is a multi-step process where interactions between cells and with the microenvironment are essential. The organ tropism, that is the propensity of a cancer to metastasize to specific organs, can be explained by se...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2014.1889
更新日期：2014-02-01 00:00:00
abstract：:The discovery of oncogenes and tumor suppressors has established the original concept of cancer development based on a cascade of spontaneously occurring somatic mutations. It is now well known that genomes of cancer cells are deeply rearranged and that these rearrangements have devastating consequences on their organ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2010.1200
更新日期：2010-11-01 00:00:00
abstract：:The treatment of the advanced ovarian adenocarcinoma, most frequently stage at diagnostic, relies on association of surgery and chemotherapy. The current standard is the association carboplatine-paclitaxel. In spite of this treatment, relapses are frequent, and the prognosis thus remains very reserved. Presently the c...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2009.0987
更新日期：2009-12-01 00:00:00
abstract：PURPOSE:GemOx was defined as a D1-D2 schedule, based on preclinical data. In order to improve convenience for patients, we evaluated a simplified D1-D1 GemOx regimen (S-GemOx) in MPA. PATIENTS AND METHODS:Patients (pts) with MPA were 2:1 randomly assigned for first-line treatment to S-GemOx (gemcitabine 1,000 mg/m(2),...
journal_title：Bulletin du cancer
pub_type： 杂志文章,随机对照试验
doi：10.1684/bdc.2009.0871
更新日期：2009-05-01 00:00:00
abstract：:The evidence that genetic factors are of some importance in the etiology of cancer originates has been determined by genetic epidemiology, molecular biology, cytogenetics. Genetic counselling is one of the possible strategies for controlling cancer through genetics. Genetic counselling in this field more often concern...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:The first endoscopic gall-bladder ablation was performed in France, twenty years ago. NOTES (natural orifices transluminal endoscopic surgery) is a new step towards surgery leaving no scar. Is surgery's paradigm changing now ? This short study will focus on the epistemologic and ethical changes which have been generat...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2007.0518
更新日期：2007-12-01 00:00:00
abstract：:Local control and sphincter preservation are the two challenges of anal canal cancer treatment. These tumors are radio- and chemo-sensitive and treatment moved from surgical approach, with abdominoperineal resection, to definitive radiation therapy with or without concurrent chemotherapy. Randomised trials proved the ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：:The tolerance and the clinical and histological efficacy of a neoadjuvant chemotherapy FEC-HD including hematopoietic growth factors have been studied in 40 patients with stade II or III breast cancer between February 1991 and February 1997. Four courses were given, every 21 days, with 5-fluorouracil (750 mg/m2/day D1...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1999-02-01 00:00:00
abstract：INTRODUCTION:Surgical treatment of malignant primitive tumors of bone needs a precise preoperative assessment of tumor local extension. Joint involvement (JI) represents the most important finding to determine, for the choice of surgical procedure (intra- or extra-articular resection). OBJECTIVE:To determine the value...
journal_title：Bulletin du cancer
pub_type： 杂志文章,多中心研究
doi：10.1016/j.bulcan.2016.09.018
更新日期：2016-11-01 00:00:00
abstract：:The publication of the new WHO classification of head and neck tumours in 2017 brought major modifications. Especially, a new chapter is dedicated to the oropharynx, focusing on the description of squamous cell carcinoma induced by the virus Human Papilloma Virus (HPV), and new entities of tumors are described in nasa...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1016/j.bulcan.2018.04.004
更新日期：2018-06-01 00:00:00
abstract：:Oncolor, the French regional cancer network of Lorraine, proposes clinical guidelines for the diagnosis, the treatment and the follow-up of cancers. In addition to paper documents, two computerized supports, a web site and the Kasimir software have been developed to make the use of these guidelines and their updating ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2003-04-01 00:00:00
abstract：:The biological diagnosis of prostatic carcinoma in relation with benign prostatic hypertrophy is essentially realized by the evaluation of plasma PAP or medullar PAP, the increase of which rises to 70% of the cases. This evaluation contains also other biochemical markers such as CK-BB, glucose-6-phosphate dehydrogenas...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:The registry of digestive tumors of the department of Cote-d'Or recorded between 1976 and 1982, among 1543 colorectal cancers, 142 cases (9.2%) diagnosed with acute obstruction. Distribution of the tumors along the large bowel was as follows: rectal cancers were rarely obstructive (3.8%) whereas it was a more common f...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:The provision of medical care consumes resources, and the resources available for the provision of medical care are limited. Decisions are being made at many levels of the Health Care System, including providers and fiscal intermediaries, to allocate these resources. Such decisions, however, are often inconsistent wit...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：BACKGROUND AND AIM:CABYR, a calcium-binding tyrosine phosphorylation regulated fibrous sheath protein, was initially reported to be testis-specific and subsequently shown to be present in brain tumors, pancreas cancer and lung cancer. This study aimed to investigate the expression and effects of the CABYR-c transcript ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2011.1538
更新日期：2012-03-01 00:00:00
