Abstract：
:The registry of digestive tumors of the department of Cote-d'Or recorded between 1976 and 1982, among 1543 colorectal cancers, 142 cases (9.2%) diagnosed with acute obstruction. Distribution of the tumors along the large bowel was as follows: rectal cancers were rarely obstructive (3.8%) whereas it was a more common feature in the sigmoid (14.2%), the caecum (12.2%) and the transverse colon (15.8%). Symptoms preceded the acute obstruction in 39.7% of the cases. Limited tumors were rare in obstructive cancers, 2.8% were Dukes A, 30.3% Dukes B; the corresponding data for non obstructive cancers were 15.6 and 27.7% respectively (P less than 0.01). Treatment was surgical in 97.9% of obstructive cancers. Surgery was more often palliative in obstructive tumors (45.8%) than in the other types of tumors (21.3%; P less than 0.01). The postoperative mortality rate was 30.9%, ie 21.6% after curative surgery, 30% after palliative surgery, 43.6% after derivative surgery. The overall survival rates for obstructive cancers were 42.7% after one year and 17.6% after 5 years; they were respectively 59.1 and 31.1% for non obstructive cancers (P less than 0.001). After curative surgery and excluding postoperative mortality prognosis was the same for obstructive and obstructive cancers within the same Dukes' stage. This study permitted to highlight the rather high frequency of obstructive colorectal cancers, and their bad prognosis linked to the extension of the tumors and to high postoperative mortality rates.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Boutron MC,Faivre J,Rallier du Baty H,Meny B,Bedenne L,Hillon P,Klepping Csubject
Has Abstractpub_date
1988-01-01 00:00:00pages
347-54issue
4eissn
0007-4551issn
1769-6917journal_volume
75pub_type
杂志文章abstract：:Pain is frequent in the course of cancer and can have negative consequences on patients quality of life. The great majority of patients can be helped by simple treatments. The prescription of morphine (M) must be preceded by some explanations. In order to verify the reality of these explanations, a study was done in a...
journal_title：Bulletin du cancer
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1998-04-01 00:00:00
abstract：:Seventy-five patients with locally advanced non small cell lung carcinoma were entered in a phase II study combining chemotherapy (vindesine, lomustine, cisplatin and cyclophosphamide) and radical thoracic radiotherapy delivering a total dose of 60-65 Gy. Patients were regularly assessed by radiological and fiberoptic...
journal_title：Bulletin du cancer
pub_type： 临床试验,杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Thymidine kinase (TK) was assayed in the cytosol of 210 primary breast cancers to assess its predictive value for response to first line chemotherapy and hormonotherapy. We performed correlations between TK and the other prognosis factors of breast cancer. TK activity is correlated with SBR grading and estrogen recept...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:In a dozen years of development, irinotecan (CPT11) became one of major therapeutics in the taking care of the metastatic colorectal cancer (CCRM). First used in monotherapy every three weeks, irinotecan has been later developed in association with 5FU and folinic acid according to two modalities of administration (bo...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2006-05-01 00:00:00
abstract：:Fifty-one patients with non-Hodgkin's lymphoma refractory or relapsing after CHOP-like regimen, underwent a salvage chemotherapy by VPH: etoposide 100 mg/m2/d, D1 to D3, cisplatin 20 mg/m2/d, D1 to D5, ifosfamide 1 g/m2/d D1 to D5, mesna 1.2 g/m2/d D1 to D5, every 4 weeks. Among 46 evaluable patients for efficacy, 21 ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：:Statistical, biological and chemical data on the carcinogenic effect of tobacco smoke are given and are discussed. The epidemiological studies have clearly shown the particularly noxious action of inhalation, and the direct ratio between the risk and the number of cigarettes smoked. The laboratory experiments on biolo...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：OBJECTIVE:Describe the implementation and preliminary results of the “Experimental Program Personalized care” in patients with Head and Neck cancer. MATERIALS AND METHODS:After being selected a graduate nurse status, called coordination, participated in the development of forms of detection needs and concerns of patie...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2014.2040
更新日期：2014-10-01 00:00:00
abstract：:Doxifluridine, a new fluorouracil analog with a low myelosuppressive effect, has recently been subject to various disease-oriented, Phase II trials. For the present evaluation of drug tolerance, the Phase II data of 114 patients having received 376 doxifluridine cycles has been used. The treatment cycles consisted of ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Malnutrition is frequently observed in oncology. The consequences on patient survival, chemotherapy toxicities and quality of life need to be identified and treated appropriately. A set of tools are available that enable clinicians to diagnose and detect malnutrition. Each tool must consider three items: the patient's...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1016/j.bulcan.2016.06.003
更新日期：2016-09-01 00:00:00
abstract：:For most diseases, one observes great variability in clinical course and response to therapy which should be taken into account in the design and the analysis of clinical trials. Eligibility criteria and stratified randomization use prognostic knowledge. A suitable analysis of randomized studies includes: (1) checking...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) is now an entire part of treatment of peritoneal dissemination of colorectal malignancy, and it's possible to hope prolonged survival. This treatment is more and more codified. Four indications are recognized by some tree national evaluation committees: ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2008.0553
更新日期：2008-01-01 00:00:00
abstract：FOCAL TREATMENT AND SYSTEMIC THERAPY IN METASTATIC KIDNEY CANCER:COMPLEMENTARY APPROACHES: To treat metastatic renal cell carcinoma, therapies used are with an oral intake, for the vast majority, and have many side effects that may compromise observance. Strategies of drug holiday have been studied and, in case of an i...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/S0007-4551(18)30376-X
更新日期：2018-12-01 00:00:00
abstract：:The clinico-pathological and epidemiological features of 119 cases of Kaposi's sarcoma diagnosed during the years 1979-1986 in the main pathology department of Rwanda are presented. Skin involvement (89%) was predominant with almost 70% of cutaneous lesions localised on the lower limbs; 11% of cases presented with ext...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1989-01-01 00:00:00
abstract：:From a series of 89 clinically inflammatory breast cancers, the authors settle a subgroup of tumors, the infiltrative ductal carcinomas with a pleomorphic structure. They have better histological and hormonal prognostic criteria than the other carcinomas, especially the infiltrative ductal carcinomas with an atypical ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：UNLABELLED:Experimental study of rhabdomyosarcoma with successive transplantation upon C3H/He mice, treated by irradiation (Co 60) and combined irradiation-hyperbaric oxygen (HBO), dating from 3, 14 and 15 days after transplantation. The data (tumor volume evolution, histological modifications, pulmonary metastases) ar...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:In our hospital, most of the patients with a cancer received palliative chemotherapy. Then, we wanted to know in which conditions these therapies were realised and most specially for patients with lung cancer. We noted the stage of the disease at the diagnosis, the median survival duration after diagnosis and the medi...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:Newly synthesized dipyrido [4,3-b] [3,4-f] indole compounds have a structural similarity with the DNA intercalating agents ellipticines (pyrido-carbazoles). The procedure of synthesis of these compounds allows the addition of a lateral chain in position 1 of the nucleus. Comparison is made between different substituti...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Glioblastoma multiforme still remains, at present, the most frequent and deadly primary malignant glioma in adult. Despite safer and larger neurosurgical resections, patients almost always relapse very close or inside the tumor bed. Since more than 20 years, radiation therapy (RT) continue delivering the same dose of ...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2005-04-01 00:00:00
abstract：:The study of cases treated between 1970 and 1984 at the Institut Curie, in women aged 40 years and under, was undertaken in order to determine the influence of age on prognosis. The incidence of these cases was stable throughout the 15 years study period as was the very high incidence of earlier cases: 84.5%. Earlier ...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Merkel cell carcinoma (MCC) is an uncommon neuro-endocrine tumor of the sun-exposed skin predominantly observed in white patients in the sixth decade of the life. In electron microscopy MCC characteristically contains dense core secretory granules. This tumor expresses both epithelial (keratins of low molecular weight...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：:Acute and chronic renal failures are very common after allogeneic HSCT. These complications have a real impact on mortality and morbidity of transplant recipients. Within the framework of the ninth workshops of practice harmonization of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-...
journal_title：Bulletin du cancer
pub_type： 共识发展会议,杂志文章,实务指引
doi：10.1016/j.bulcan.2019.05.002
更新日期：2020-01-01 00:00:00
abstract：:The first endoscopic gall-bladder ablation was performed in France, twenty years ago. NOTES (natural orifices transluminal endoscopic surgery) is a new step towards surgery leaving no scar. Is surgery's paradigm changing now ? This short study will focus on the epistemologic and ethical changes which have been generat...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1684/bdc.2007.0518
更新日期：2007-12-01 00:00:00
abstract：:Pulmonary sarcomatoid carcinomas are a rare group of tumors accounting for about 1 % of non-small cell lung carcinoma (NSCLC). In 2004, World Health Organization classification united under this name all the carcinomas with sarcomatous or sarcomatous-like component with spindle cell or giant cell appearance. There are...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1684/bdc.2012.1619
更新日期：2012-10-01 00:00:00
abstract：:296 intraoral minor salivary gland tumors were observed among 702 salivary tumors. The study emphasizes a frequent palatine location, observed in more than 50 per cent of theses tumors. Pleiomorphic adenomas (or so called mixed tumors), are frequently encountered; but it is noteworthy that the proportion of muco-epide...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Serotonin (5-Hydroxytryptamine) seems to play a dominant role in triggering vomiting induced by cytotoxic agents through the stimulation of 5-HT3 receptors. They have been observed in the GI tract as well as in the brain (area postrema). Ondansetron is a specific antagonist of 5-HT3 serotonin receptors. Its anti-emeti...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to explore the risk factors that were associated with central lymph node metastasis (CLNM) in patients with clinical nodal negative differentiated thyroid carcinoma (cN0 DTC) after prophylactic central neck dissection (pCND). The influence of pCND on TNM staging and recurrence ri...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：10.1016/j.bulcan.2016.04.003
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:To establish the recommended dose (RD) of the thymidylate-synthase inhibitor ZD9331 administered with irinotecan (CPT-11) in patients with pretreated metastatic colorectal cancer, and to assess toxicity profile, pharmacokinetics (PK), and anti-tumor activity in a phase I/II open, multicenter, intrapatient ch...
journal_title：Bulletin du cancer
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：2004-12-01 00:00:00
abstract：:Colorectal primary signet ring cell carcinoma (SRCC) is a rare entity accounting for nearly 1% of all colorectal carcinomas. It is an independent prognostic factor associated with less favorable outcome. This aggressiveness is mainly due to the intrinsic biology of these tumors. Here is an overview of the literature r...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：10.1016/j.bulcan.2015.07.005
更新日期：2015-10-01 00:00:00
abstract：:Non transformed epithelial hepatic cells (established cell line and adult rat hepatocytes) treated by liver tumor promoters, phenobarbital and biliverdin, for 24 and 48 h showed a fragmentation and loss of F-actin and a depolymerisation of microtubules. This pattern closely resembles that of transformed cells which we...
journal_title：Bulletin du cancer
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Cell immunotherapy aims at treating patients by stimulating their own immune system using appropriate cells. This approach is one of the most promising therapeutic strategy against cancer. The use of cells, the mobilization of a system, the targeting of interactions between the immune system and the tumor constitute t...
journal_title：Bulletin du cancer
pub_type： 杂志文章,评审
doi：
更新日期：2003-08-01 00:00:00
