Abstract:
:Colorectal cancer occurs after the age of 75 in 50% of the case, but elderly patients are under-treated and far from an optimal management of their disease. Principles of colorectal cancer management after the age of 75 are theoretically the same than for younger patients, but physiological age, comorbidities and patient's wishes should be taking into account. Treatment should be individually based and discussed during multidisciplinary meeting with oncologists and geriatrics after a complete geriatric evaluation. Surgery remains the only curative treatment and should be discussed when feasible.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Mitry Edoi
10.1684/bdc.2007.0545subject
Has Abstractpub_date
2008-05-28 00:00:00pages
F70-3eissn
0007-4551issn
1769-6917pii
bdc.2007.0545journal_volume
95 FMC Oncopub_type
杂志文章abstract::Whereas medicine is progressing in illness treatment that used to be incurable, physicians are still faced with treatment failure. Hippocrates used to say: "primum non nocere" [1]. When the patient cannot expect benefit from potentially aggressive care, current or possible treatments have to be challenged to leave jus...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2009.0910
更新日期:2009-07-01 00:00:00
abstract::We report a case of renal cell carcinoma presenting with bilateral adrenal masses diagnosed by ultrasonography four years after nephrectomy. The histopathological examination of the trucut biopsy specimens obtained percutaneously by ultrasound guidance revealed bilateral adrenal mestastases of renal cell carcinoma. ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1994-02-01 00:00:00
abstract::Hodgkin's and non-Hodgkin's lymphomas are frequent and represent a heterogenic group of haematologic diseases. Prognostic factors allow to classify patients into homogeneic risk groups, to adapt treatment proposal to disease's risk and, in some cases, to avoid over-treatment. For all lymphomas, the first step is to de...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2009.0844
更新日期:2009-04-01 00:00:00
abstract::The aims of this study was to estimate and describe the reasons of use of complementary medicine in patients with a cancer treated in a French oncology department. An anonymous questionnaire was proposed to patients during treatment or follow-up in an oncology department. It was a descriptive study over 207 questionna...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2007-11-01 00:00:00
abstract::Cytogenetic, molecular and phenotyping features of malignant hematologic diseases succeeded in improving their management by a more accurate stratification of patients according to several groups of risk and by providing a rational for targeted therapy. Three major types of treatment (excluding cellular therapy) are c...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2011.1412
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The standard treatment in first line of advanced or metastatic urothelial bladder cancer (MBC) is the association of Gemcitabine and Cisplatin (GC). Avelumab, an anti-PD-L1 agent, has recently demonstrated efficacy. The objective is to evaluate the combination of these 3 agents. METHODS:This phase II random...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/S0007-4551(20)30280-0
更新日期:2020-06-01 00:00:00
abstract:PURPOSES:Analyze the relationship and expectations of cancer patients towards the community pharmacist in a pharmaceutical care coordination project. METHODS:In November 2014, a questionnaire was distributed to ambulatory patients of a university hospital specialized in oncology. Thirteen questions explored the consum...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2017.11.017
更新日期:2018-03-01 00:00:00
abstract::In this review, we will summarize the guidelines on the evaluation of anticancer medicinal products in man and definitions for genomic biomarkers (FDA validated), pharmacogenomics, pharmacogenetics, genomic data and sample coding categories. ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2008.0733
更新日期:2008-10-01 00:00:00
abstract::In response to the evolution of the information-seeking behaviour of patients and concerns from health professionals regarding cancer patient information, the French National Federation of Comprehensive Cancer Centres (FNCLCC) introduced, in 1998, an information and education program dedicated to patients and relative...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract::Despite great improvements in the outcome of patients with lymphoma, some may still relapse or present with primary refractory disease. In these situations, allogeneic haematopoietic cell transplantation (allo-HCT) is a potentially curative option, in particular in the case of relapse after autologous stem cell transp...
journal_title:Bulletin du cancer
pub_type: 共识发展会议,杂志文章,实务指引,评审
doi:10.1016/j.bulcan.2017.08.008
更新日期:2017-12-01 00:00:00
abstract::In a case of glioblastoma, the following karyotype was determined: 47, X, - Y, + der(1) t(1;9)(p21;p23), t(1;9)(p21;p23), + 3, + 7, der(9) t(Y;9)(q11;p21), - 13, t(13;16)(p13,p11), del(14)(q11q22). Classical satellite DNAs are mainly located in chromosomes 1, 9, 15, 16 and Y. Because, most of these chromosomes were im...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::Soft tissue sarcomas (STS) are a set of very heterogeneous tumors with numerous histological categories. The development of the molecular biology allowed identifying recurring molecular anomalies in certain subgroups of sarcomas, being able to represent diagnostic, prognosis and therapeutic tools. The molecular classi...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/j.bulcan.2014.12.005
更新日期:2015-01-01 00:00:00
abstract::Based upon the literature, we discuss epidemiological, histopathological, clinical and treatment aspects of postirradiation sarcomas. The risk of postirradiation sarcoma is very low and negligible in comparison with the beneficial effect of radiotherapy, and it should not be a major factor influencing treatment decisi...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1997-09-01 00:00:00
abstract::A retrospective study of 337 cases of cervix cancers in women aged 35 years and under, treated between 1980-1990 at the Ibn Rochd Oncology Center in Casablanca, was analyzed in order to determine the main characteristics of this disease and the influence of age on prognosis. The incidence of these cases was stable thr...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1997-04-01 00:00:00
abstract::We report a prospective study concerning the association of surgery-chemotherapy and radiotherapy in the treatment of primary high grade digestive non-Hodgkin's lymphomas in 19 patients. The analysis of 11 stages IE, 5 stages II1E and 3 stages II2E allowed us to evaluate the efficacy and the tolerance of this triple t...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::Adhesion molecules play a major role in the regulation of normal hematopoiesis. Precursor/cell matrix/endothelial interactions determine retainment or release of hematopoietic cells from the bone marrow microenvironment. Consequently, changes in the affinity or quantitative expression of adhesion molecules on either t...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1999-03-01 00:00:00
abstract::296 intraoral minor salivary gland tumors were observed among 702 salivary tumors. The study emphasizes a frequent palatine location, observed in more than 50 per cent of theses tumors. Pleiomorphic adenomas (or so called mixed tumors), are frequently encountered; but it is noteworthy that the proportion of muco-epide...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::As compared to conventional axillary dissection, the sentinel node technique is accompanied by reduced morbidity and shorter hospital stay. Based on available data, the use of this technique does not seem to yield higher rates of axillary recurrence. A combination of both radioisotope detection and blue dye increases ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2009.0879
更新日期:2009-06-01 00:00:00
abstract::Recommendations for the management of gastrointestinal stromal tumours (GIST) in children and adolescents do presently not exist. Thus, a summary of the current literature was conducted serving as a basis for the development of optimal management strategies for childhood GIST. Pediatric cases of GIST may occur sporadi...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2010.1296
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Sorafenib is the standard treatment for advanced hepatocellular carcinoma (HCC). Due to its peculiar toxicities, improving patient's tolerance may need close follow-up. Nurses can play a crucial role, by driving a patient education program (EP). We aimed to prove that adding EP to usual care (UC) improves pa...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1016/j.bulcan.2016.09.017
更新日期:2016-11-01 00:00:00
abstract::Forty-six tumors from patients with oropharyngeal carcinoma were analysed by flow cytometry after injection of bromodeoxyuridine (Budr) for the labelling index, the duration of S phase and the potential doubling time (Tpot). The results show large variations in Tpot (from 2.6 to 16.7 days) among these tumors from the ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::Cancer patients are often moved inside the hospital to different examination clinics, such as radiology, CT scan, MRI... and to treatment clinics, such as radiotherapy. These transports induce important pain phenomena, not really recognized by professional teams. As these kinds of pains are expected and can be prevent...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2008.0638
更新日期:2008-05-01 00:00:00
abstract::A retrospective, morphological and immunochemical study was performed on 60 bone marrow biopsies (BOM) and 12 tumor specimens surgically excised, from 9 patients with neuroblastoma (NB). Immunochemistry concerned "neuron-specific enolase" (NSE), chromogranin A (CGA) and synaptophysin (SP). The results of immunochemica...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::In 2003, there was 147,000 deaths attributed to cancer in France, 88,000 in men and 59,000 in women. Cancer mortality rates have been decreasing since 1987 in the male population and since the late 60's in the female population, the decrease is larger for the male population. This decrease is observed for most sites o...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Macroautophagy or autophagy is a degradative pathway terminating in the lysosomal compartment after the formation of a cytoplasmic vacuole that engulfs macromolecules and organelles. The recent discovery of the molecular controls of autophagy that are common to eukaryotic cells from yeast to human suggests that the ro...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2006-05-01 00:00:00
abstract::DNA methylation is known to be related to the regulation of gene expression. DNA methylation patterns are modified in tumors compared to normal tissue, and in some cases, these variations are linked to cancer progression. Molecular biology techniques are generally used to evaluate DNA methylation status. We describe h...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::Surgical oncology requires an indispensable cultural and interdisciplinary approach of cancer. It needs a solid surgical formation combined with knowledges in biology, pathology, radiology, chemotherapy, and radiotherapy so oncologist surgeons are better able to define the limits of intervention according to the natur...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::Between October 1987 and June 1992, 244 patients with metastatic renal carcinoma were referred to our Institute. One hundred and sixty-nine were included in immunotherapy protocols. The 40 most recent patients were included in the ongoing multicentric randomised Crecy study. The previous patients were treated with IL2...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-07-01 00:00:00
abstract::Ewing tumours are characterised as tumours consisting of small, blue, round malignant cells that may exhibit varying degrees of neural differentiation. Most of them arise in bony sites, and they represent the second commonest primary osseous malignancy in and adolescence and young adults. During the past 30 years, che...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2010.1120
更新日期:2010-06-01 00:00:00
abstract::This study is devoted to the analysis of the surgical treatment of cancer of the uterine cervix, stage III. Three circumstances are evaluated: - Stage III with urinary disease the purpose of the surgical treatment is most often to save the renal function;--Recurrences after radiotherapy where surgery is the only poss...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00