Abstract:
:Despite great improvements in the outcome of patients with lymphoma, some may still relapse or present with primary refractory disease. In these situations, allogeneic haematopoietic cell transplantation (allo-HCT) is a potentially curative option, in particular in the case of relapse after autologous stem cell transplantation. Recently, novel agents such as anti-PD1 and BTK inhibitors have started to challenge the use of allo-HCT for relapsed or refractory lymphoma. During the 2016 annual workshop of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC), we performed a comprehensive review of the literature published in the last 10 years and established guidelines to clarify the indications and transplant modalities in this setting. This manuscript reports on general considerations regarding allo-HCT for lymphoma and elaborates on the use of alternative donors in this setting.
journal_name
Bull Cancerjournal_title
Bulletin du cancerauthors
Gauthier J,Chantepie S,Bouabdallah K,Jost E,Nguyen S,Gac AC,Damaj G,Duléry R,Michallet M,Delage J,Lewalle P,Morschhauser F,Salles G,Yakoub-Agha I,Cornillon Jdoi
10.1016/j.bulcan.2017.08.008subject
Has Abstractpub_date
2017-12-01 00:00:00pages
S106-S111issue
12Seissn
0007-4551issn
1769-6917pii
S0007-4551(17)30269-2journal_volume
104pub_type
共识发展会议,杂志文章,实务指引,评审abstract::This study is devoted to the analysis of the surgical treatment of cancer of the uterine cervix, stage III. Three circumstances are evaluated: - Stage III with urinary disease the purpose of the surgical treatment is most often to save the renal function;--Recurrences after radiotherapy where surgery is the only poss...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Statistical, biological and chemical data on the carcinogenic effect of tobacco smoke are given and are discussed. The epidemiological studies have clearly shown the particularly noxious action of inhalation, and the direct ratio between the risk and the number of cigarettes smoked. The laboratory experiments on biolo...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::Treatment of metastatic renal cell carcinoma with interleukin 2 (IL2) remains controversial despite the authorization from the French government for IL2 with the West schedule in this disease. We report herein the study of the Institute Gustave-Roussy of 73 patients, who received from 1989 to 1991 a new schedule of hi...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract::Occupational risk factors represent a significant part of cancer causes and are involved in all type of cancers. Nonetheless, the frequency of these cancers is largely under-estimated. Parallel to the epidemiological approach (collective), the concept of occupational cancer is often linked (at the individual level) to...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract::Advances in medical imaging have greatly enhanced the speciality of radiation oncology by allowing more healthy tissue to be speared for better tumour coverage. Positron emission tomography (PET) with the glucose analogue [18F]-fluoro-2-deoxy-D-glucose (FDG) is a functional imaging method that has become widely used i...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2007-01-01 00:00:00
abstract::Over the last few years evaluation of quality of diagnostic and therapeutic care has become one of the most controversial and fastest growing fields of research in many areas of medicine. In this situation, oncology represents a model case as the conditions in which new therapeutic strategies are tested and implemente...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::There are very few active drugs in the treatment of metastatic gastric carcinoma. Among new drugs, docetaxel has shown one of the most important activity. With precise evaluation of objective response, this drug has demonstrated a 20% response rate in monotherapy. The favorable toxicity profile of this compound allowe...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2004-03-01 00:00:00
abstract::When confluent human skin cultures are ultraviolet (UV)-irradiated before infection with Herpes Simplex type 1 virus (HSV), their capacity to support virus growth is impaired. When the time interval between UV-exposure and infection is increased up to 36 hours, different recoveries of HSV production capacity are obser...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::Gangliosides are glycosphingolipids which contain neuraminic acid. Although they are present in the plasma membranes of all cells, gangliosides are expressed differently, both quantitatively and qualitatively, in certain types of cancer. Modifications in ganglioside composition may account for some of the abnormal int...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract::The estimated number of cancers diagnosed in 2002 is 150,000 in the male population and 120,000 in the female population and there were close to 88,000 cancer deaths among men and 59,000 cancer deaths among women in France. The most frequent cancer sites in the male population are prostate, lung, colon, intestine and ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::The oncornaviruses share several biological, biochemical, and structural properties that distinguish them from other RNA viruses. Rous sarcoma virus, a representative of avian oncornaviruses, manifests two major functions: cell transformation and virus replication. Both functions are independent, and are expressed sep...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract::The proliferation and the differentiation of B lymphocytes is under the control of T cell and macrophage produced cytokines which drive resting B cells to the state of antibody-producing plasma cells. Antibodies exert a feedback control of their own production via their interaction with Fc receptor (FcR) bearing cells...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract::Colorectal cancer (CRC) is the second leading cause of cancer-related mortality in France. Recently, colorectal cancer subtyping consortium (CRCSC) identified 4 consensus molecular subtypes (CMS). CMS1 is enriched for CRC with deficient DNA mismatch repair system (dMMR) and tumors with mutated BRAF. Intriguingly, CMS1...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1016/S0007-4551(15)31220-0
更新日期:2015-06-01 00:00:00
abstract::Indications and choice of antiepileptic drugs (AED), treatments for cerebral edema and prophylactic and curative treatments of thromboembolic complications of brain metastasis are discussed. ...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2012.1689
更新日期:2013-01-01 00:00:00
abstract::Since January 1981, 58 patients with postoperative recurrences or inoperable rectal cancer have been included in a trial featuring a neutron boost after an initial series of irradiation given by the classical high energy photon procedure. This group irradiated at the Neutrontherapy Unit in Orléans was compared to a hi...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::From a series of 89 clinically inflammatory breast cancers, the authors settle a subgroup of tumors, the infiltrative ductal carcinomas with a pleomorphic structure. They have better histological and hormonal prognostic criteria than the other carcinomas, especially the infiltrative ductal carcinomas with an atypical ...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::The objective of this study is to compare morbidity between 2 surgical procedures of axillary clearance: functional lymphadenectomy by classical dissection versus axillary dissection prepared by liposuction (Suzanne's procedure). Two hundred consecutive patients treated for breast cancer were included in a prospective...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1997-03-01 00:00:00
abstract::In a case of glioblastoma, the following karyotype was determined: 47, X, - Y, + der(1) t(1;9)(p21;p23), t(1;9)(p21;p23), + 3, + 7, der(9) t(Y;9)(q11;p21), - 13, t(13;16)(p13,p11), del(14)(q11q22). Classical satellite DNAs are mainly located in chromosomes 1, 9, 15, 16 and Y. Because, most of these chromosomes were im...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::Important progress have been recently achieved in the management of Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL). Prognostic factors are now better defined in HD thanks to new biologic and radiologic information which complete old and relevant clinical factors. These parameters are expected to improve decis...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract::We report on a case of 5-fluorouracil induced neurotoxicity during 5-fluorouracil cisplatin combination chemotherapy for advanced head and neck squamous cell carcinoma. The initial manifestations included an acute cerebellar syndrome and peripheral neuropathy. Computed tomography of the brain was normal. The results o...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Surgical oncology requires an indispensable cultural and interdisciplinary approach of cancer. It needs a solid surgical formation combined with knowledges in biology, pathology, radiology, chemotherapy, and radiotherapy so oncologist surgeons are better able to define the limits of intervention according to the natur...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:GemOx was defined as a D1-D2 schedule, based on preclinical data. In order to improve convenience for patients, we evaluated a simplified D1-D1 GemOx regimen (S-GemOx) in MPA. PATIENTS AND METHODS:Patients (pts) with MPA were 2:1 randomly assigned for first-line treatment to S-GemOx (gemcitabine 1,000 mg/m(2),...
journal_title:Bulletin du cancer
pub_type: 杂志文章,随机对照试验
doi:10.1684/bdc.2009.0871
更新日期:2009-05-01 00:00:00
abstract::The diet of the cancer patient is a major focus of prevention and treatment strategy of the recent plans that fight against cancer. It is sometimes reduced to a rapid series of more or less general advice, often interfered by other sources of information, more or less conventional. In this pathological situation where...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2014.1905
更新日期:2014-03-01 00:00:00
abstract::Testicle germ cells tumors are the most common young men neoplasm. The incidence is maximal in Scandinavian countries. Cryptorchidism is a predisposing factor. Diagnosis is clinic, first treatment is radical orchidectomy by inguinal incision, after study of tumor markers. Histology shows seminoma or non seminomatous t...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:
更新日期:1998-09-01 00:00:00
abstract::Sentinel lymph node (SLN) biopsy is fast becoming the standard for testing lymph node involvement in many institutions. However questions remain as to stage underestimation. The aim of this study was to analyse this specific risk in a retrospective study. Between 1975 to 1999, 1,636 patients underwent a breast cancer ...
journal_title:Bulletin du cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::The treatment of the advanced ovarian adenocarcinoma, most frequently stage at diagnostic, relies on association of surgery and chemotherapy. The current standard is the association carboplatine-paclitaxel. In spite of this treatment, relapses are frequent, and the prognosis thus remains very reserved. Presently the c...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:10.1684/bdc.2009.0987
更新日期:2009-12-01 00:00:00
abstract::The dismal outcome of ovarian, fallopian tube, and primary peritoneal carcinomas calls for an increase in surgical aggressiveness. After a long era during which incomplete cytoreduction was considered acceptable, it has been established that the outcome is directly related to the amount of diseased tissue left in plac...
journal_title:Bulletin du cancer
pub_type: 杂志文章,评审
doi:10.1684/bdc.2009.0989
更新日期:2009-12-01 00:00:00
abstract::In man, the period of maximum risk for the embryo and foetus is between the second and tenth week after conception. The most frequent and most severe malformation is microcephaly which in extreme cases is accompanied by mental retardation. The results of studies in experimental animals and man agree that it is impossi...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::The results obtained in the treatment of 45 cases of soft tissue sarcomas are presented. All cases were reviewed and classified according to the modern criteria of malignancy. The treatment schedule comprised: (1) preoperative irradiation: 2 sessions of 6.50 Gy in 48 hours, target volume: whole limb segment; (2) surgi...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::The evolution of anti-cancer chemotherapy has led to long duration treatments, which preferentially are given at home, with the participation of the general practitionner (G.P.). The indications and general supervision of these belong to the oncologist, so thus necessitates a coordinated effort between the many physic...
journal_title:Bulletin du cancer
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00