[Symptomatic management of brain metastasis].

abstract：OBJECTIVE:To assess the feasibility and efficacy of cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) without adjuvant chemotherapy for relapsed or persistent advanced ovarian cancer. METHODS:This observational study included stage IIIC ovarian cancer patients due to undergo CRS...

journal_title：Bulletin du cancer

authors： Carrabin N,Mithieux F,Meeus P,Trédan O,Guastalla JP,Bachelot T,Labidi SI,Treilleux I,Rivoire M,Ray-Coquard I

更新日期：2010-04-01 00:00:00

abstract：:Between October 1987 and June 1992, 244 patients with metastatic renal carcinoma were referred to our Institute. One hundred and sixty-nine were included in immunotherapy protocols. The 40 most recent patients were included in the ongoing multicentric randomised Crecy study. The previous patients were treated with IL2...

journal_title：Bulletin du cancer

authors： Négrier S,Mercatello A,Coronel B,Lanier F,Merrouche Y,Bret M,Blay JY,Lasset C,Thiesse P,Carrie C

更新日期：1993-07-01 00:00:00

abstract：:Announcing a cancer diagnosis, but also a relapse, a progression of the disease, or transition towards palliative care constitute particularly difficult communication issues for the patient as well as for the clinician, during the trajectory of care. The objectives of this article is to present the clinical stakes of ...

journal_title：Bulletin du cancer

authors： Dolbeault S,Brédart A

更新日期：2010-10-01 00:00:00

abstract：:Adjuvant chemotherapy after apparently complete resection of gastrointestinal cancer may be theoretically justified by the high rate of local and metastatic recurrences. However, the results of controlled trials are generally disappointing, even if some of them have recently suggested some hope, chiefly for adjuvant t...

journal_title：Bulletin du cancer

authors： Martin F

更新日期：1984-01-01 00:00:00

abstract：:Apparition of new tools in the therapy of multiple (MM) strengthens the need for valuable prognostic categorization of each patient in order to propose the most adequate treatment. Prognostic factors in MM can be divided in four groups. The first, including beta 2 microglobulin (beta 2m), hemopoiesis impairment, osteo...

journal_title：Bulletin du cancer

authors： Bauduer F,Troussard X,Delmer A

更新日期：1993-12-01 00:00:00

abstract：:The concentrations of cellular retinoic acid binding protein (cRABP) and free cellular retinol binding protein (cRBP) were determined by ultracentrifugation in sucrose gradient in the cytosol of 41 human skin tumours (14 melanomas, 19 basal cell carcinomas, 8 squamous cell carcinomas). cRBP was found respectively in 3...

journal_title：Bulletin du cancer

authors： Delarue JC,Avril MF,Prade M,Petit JY

更新日期：1986-01-01 00:00:00

abstract：:When cells are exposed to ionizing radiation, they initiate a complex response that includes the arrest of cell cycle progression in G1 and G2, apoptosis and DNA repair. DNA is an important subcellular target of ionizing radiation, but oxydative damage to plasma membrane lipids initiates signal transduction pathways t...

journal_title：Bulletin du cancer

authors： Teyssier F,Bay JO,Dionet C,Verrelle P

更新日期：1999-04-01 00:00:00

abstract：:Cells in spleens from tumor bearing animals were found to inhibit in vitro reactivity of lymphocytes to a variety of stimulants. These suppressor cells inhibited the stimulation of normal lymphocytes by mitogens : P.H.A.-Con A-L.P.S. They were adherent cells, bore immunoglobulins at their surface and did not bear the ...

journal_title：Bulletin du cancer

authors： Lespinats G,Poupon MF

更新日期：1976-04-01 00:00:00

abstract：:With the objective of improvement of quality in oncology, an assessment of chemotherapy practice in hospital pharmacies in public and private hospitals was carried out by the regional committee of oncology in Lorraine. The 36 hospitals reporting using chemotherapy, had varied practices. The results of this survey lead...

journal_title：Bulletin du cancer

authors： May I,Paulus C,Vigneron J,Watelet M,Veyrier B,Bichet F,Bideaux S,Bey P

更新日期：2001-04-01 00:00:00

abstract：:Cancerogenesis is believed to be a multistep process composed of different alterations that drive the transformation of normal human cells into highly malignant derivatives. These changes include self-sufficiency in growth signals, insensitivity to growth-inhibitory signals, the evasion of programmed cell death, a lim...

journal_title：Bulletin du cancer

authors： Caers J,Van Valckenborgh E,Menu E,Van Camp B,Vanderkerken K

更新日期：2008-03-01 00:00:00

abstract：:The tolerance and the clinical and histological efficacy of a neoadjuvant chemotherapy FEC-HD including hematopoietic growth factors have been studied in 40 patients with stade II or III breast cancer between February 1991 and February 1997. Four courses were given, every 21 days, with 5-fluorouracil (750 mg/m2/day D1...

journal_title：Bulletin du cancer

authors： Darut-Jouve A,Coudert B,Jolimoy G,Belichard C,Arnoud L,Guerrin J

更新日期：1999-02-01 00:00:00

abstract：:Whole brain radiotherapy remains standard in the management of breast cancer patients with brain metastases. It allows for symptomatic improvement and good local control in most patients. However, its results remain suboptimal in terms of both efficacy and toxicity. In highly selected patients, stereotactic radiothera...

journal_title：Bulletin du cancer

authors： Kirova YM,Chargari C,Mazeron JJ

更新日期：2011-04-01 00:00:00

abstract：CONTEXT:The "Standards, Options and Recommendations" (SOR) collaborative project was initiated in 1993 by the Federation of the French Cancer Centres (FNCLCC), with the 20 French Regional Cancer Centres, several French public university and general hospitals, as well as private clinics and medical specialty societies. ...

journal_title：Bulletin du cancer

authors： Denoux Y,Blanc-Vincent MP,Simony-Lafontaine Jl,Verriele-Beurrier V,Briffod M,Voigt JJ

更新日期：2002-04-01 00:00:00

abstract：:Despite surgery, post-operative irradiation and adjuvant conventional chemotherapy, prognosis of high-grade gliomas remains poor. Carmustine (BCNU) has been shown to have limited activity at conventional dosage but is still the standard chemotherapy. Activity of chemotherapy is limited by the blood-brain barrier imper...

journal_title：Bulletin du cancer

authors： Linassier C,Destrieux C,Benboubker L,Alcaraz L,Bergemer-Fouquet AM,Jan M,Calais G,Colombat P

更新日期：2001-09-01 00:00:00

abstract：:Chemotherapy-induced peripheral neuropathy (CIPN) is common with specific semiological characteristics. When CIPN appears, there are many difficulties in guaranteeing sustained treatment, especially with optimal protocol. Moreover, CIPN have bad repercussions on quality of life after cancer disease. In this article, w...

journal_title：Bulletin du cancer

authors： Kerckhove N,Collin A,Condé S,Chaleteix C,Pezet D,Balayssac D,Guastella V

更新日期：2018-11-01 00:00:00

abstract：:CYP2D6 enzyme is implicated in the metabolism of drugs and nicotine. Genetic variability within CYP2D6, results in different CYP2D6 phenotypes. Inheritance of polymorphic CYP2D6 metabolizing enzyme is likely to be an important determinant of inter-individual variations in susceptibility to cancer. In this work, we hav...

journal_title：Bulletin du cancer

authors： Ouerhani S,Marrakchi R,Bouhaha R,Ben Slama MR,Sfaxi M,Ayed M,Chebil M,El Gaaied AB

更新日期：2008-02-01 00:00:00

abstract：:Geriatric oncology represents a novel specialty which can be defined as specific older cancer patients management. It includes a validated geriatric procedure, the comprehensive geriatric assessment, which is the best way of approaching the complex interacting medical problems of frail older patients. Geriatric assess...

journal_title：Bulletin du cancer

authors： Terret C,Gaujard S,Droz JP

更新日期：2003-01-01 00:00:00

abstract：:Since the 1980's, women treated for breast cancer are reporting moderate cognitive impairments during and after chemotherapy. These cognitive impairments may be related to chemotherapy but also to hormone therapy, psychological distress, fatigue... This work is a critical review of the literature, which reports types ...

journal_title：Bulletin du cancer

authors： Vandenbossche S,Fery P,Razavi D

更新日期：2009-02-01 00:00:00

abstract：:For more than a decade, Transforming Growth Factor Beta (TGF beta) has been intensively studied. Such studies have led to the identification of many related polypeptides which constitute the TGF beta family. These factors modulate many animal cell processes such as cell cycle progression, differentiation, adhesion, mi...

journal_title：Bulletin du cancer

authors： Benzakour O

更新日期：1994-12-01 00:00:00

abstract：:Ataxia telangiectasia (AT) is a hereditary disease transmitted in a recessive mode and characterized by chromosomal instability and radiosensitivity. AT patients have a 100-fold higher risk of cancer than the general population. Although AT is a rare disease of which the frequency has been estimated to be 1/40,000, th...

journal_title：Bulletin du cancer

authors： Stoppa-Lyonnet D,Aurias A

更新日期：1992-01-01 00:00:00

abstract：:With 2 436 deaths in 1979, ovarian cancer is relatively infrequent in France comprising but 5 per cent of female mortality from malignant disease. However, the rate of increase in mortality is considerable, 70 per cent between 1955 and 1979 or 2,9 per cent per year, greater than that for female bladder and breast canc...

journal_title：Bulletin du cancer

authors： Berlie J,Tournade MF,Chauvergne J,Bastien H

更新日期：1983-01-01 00:00:00

abstract：INTRODUCTION:Since the last cancer plan 2014-2019, the assessment of the impact of the disease on caregivers became essential. The quality of caregiving represents an important part of the patient's quality of life. The main objective was to describe the evolution of caregiver's attachment style during the first three ...

journal_title：Bulletin du cancer

authors： Bonnet M,Vadam F,Belot RA,Quibel C,Pozet A,Nerich V

更新日期：2020-11-01 00:00:00

abstract：:The authors analyze the respiratory sequelae in 19 patients with limited small cell lung carcinoma who survived for more than 30 months following an alternating chemo-radiotherapeutic combined regimen. The clinical tolerance measured with respiratory functional test is acceptable. In two patients an effort dyspnea is ...

journal_title：Bulletin du cancer

authors： de Cremoux H,Baldeyrou P,Martin M,Ruffié P,Arriagada R,Le Chevalier T

更新日期：1987-01-01 00:00:00

abstract：:Beside human papilloma virus infection, several genetic factors have been involved in susceptibility to cervical cancer. The arginine allele at codon 72 in p53 tumor suppressor gene has been reported to be a risk-factor in different ethnic groups. Our aim was to study this polymorphism as a risk-factor in Senegal. We ...

journal_title：Bulletin du cancer

authors： Ndiaye R,Dem A,Mbaye PM,Guèye PM,Diop G,Diop PA,Faye O

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:An increasing number of patients with prostate cancer (PC) are diagnosed and treated. The aim of this study was to investigate urinary incontinence (UI) and sexual dysfunction (SD) two years after treatment for localized prostate cancer (PC). METHODS:This study followed all cases of localized PC diagnosed...

journal_title：Bulletin du cancer

authors： Bessaoud F,Orsini M,Iborra F,Rebillard X,Faix A,Soulier M,Daurès JP,Trétarre B

更新日期：2016-10-01 00:00:00

abstract：:Cytogenetic, molecular and phenotyping features of malignant hematologic diseases succeeded in improving their management by a more accurate stratification of patients according to several groups of risk and by providing a rational for targeted therapy. Three major types of treatment (excluding cellular therapy) are c...

journal_title：Bulletin du cancer

authors： Baleydier F,Domenech C,Thomas X

更新日期：2011-08-01 00:00:00

abstract：:Since January 1981, 58 patients with postoperative recurrences or inoperable rectal cancer have been included in a trial featuring a neutron boost after an initial series of irradiation given by the classical high energy photon procedure. This group irradiated at the Neutrontherapy Unit in Orléans was compared to a hi...

journal_title：Bulletin du cancer

authors： Breteau N,Destembert B,Favre A,Sabattier R,Schlienger M

更新日期：1986-01-01 00:00:00

abstract：:Small cell lung carcinoma is the most frequent cancer in man. In France, the geographic distribution is not homogenous and the frequency is time-dependent. The main risk factors are smoking and some professional exposures. ...

journal_title：Bulletin du cancer

authors： Flamant R,Hill C,Benhamou S

更新日期：1987-01-01 00:00:00

abstract：INTRODUCTION:The French Patient Advocacy Group SOS Desmoid conducted a survey to measure the pain burden of desmoid tumor patients. MATERIAL AND METHODS:We used a structured questionnaire to measure the occurrence and consequences of pain. RESULTS:The pain occurrence was approximately 63%. In one-third of the cases, ...

journal_title：Bulletin du cancer

authors： Rigaux P,Lefebvre-Kuntz D,Penel N,“SOS Desmoïde”.

更新日期：2015-03-01 00:00:00

abstract：:Treatment of patients with small-cell lung cancer (SCLC) remains disappointing despite high initial complete response rates. The dramatic initial chemosensitivity of tumor cells is frustrated by the early emergence of chemoresistant clonogenic cells, regardless of front line treatments. Although the dose relationship ...

journal_title：Bulletin du cancer

authors： Le Chevalier T,Le Cesne A,Arriagada R

更新日期：1995-01-01 00:00:00